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APOLIPOPROTEIN A-I (NORWAY)

MedGen UID:
866150
•Concept ID:
C4017713
•
Finding
OMIM®: 107680

Professional guidelines

PubMed

Long-term Low-Density Lipoprotein Cholesterol-Lowering Efficacy, Persistence, and Safety of Evolocumab in Treatment of Hypercholesterolemia: Results Up to 4 Years From the Open-Label OSLER-1 Extension Study.
Koren MJ, Sabatine MS, Giugliano RP, Langslet G, Wiviott SD, Kassahun H, Ruzza A, Ma Y, Somaratne R, Raal FJ
JAMA Cardiol 2017 Jun 1;2(6):598-607. doi: 10.1001/jamacardio.2017.0747. PMID: 28291870Free PMC Article
The Metabolic Risk in Patients Newly Diagnosed with Acromegaly Is Related to Fat Distribution and Circulating Adipokines and Improves after Treatment.
Olarescu NC, Heck A, Godang K, Ueland T, Bollerslev J
Neuroendocrinology 2016;103(3-4):197-206. Epub 2015 Jan 9 doi: 10.1159/000371818. PMID: 25592241
Cardiovascular risk factors in people with different genotypes in the insertion/deletion (I/D) polymorphism at the locus for angiotensin I-converting enzyme (ACE).
Berge KE, Berg K
Clin Genet 1997 Dec;52(6):422-6. doi: 10.1111/j.1399-0004.1997.tb02562.x. PMID: 9520252

Recent clinical studies

Etiology

Effects on physical activity, physical fitness and well-being in a 36-months randomized controlled study, comparing a multimodal hospital-based intervention programme for primary cardiovascular prevention with usual care.
Bergum H, Grimsmo J, Anderssen SA, Klemsdal TO
BMC Cardiovasc Disord 2024 Apr 25;24(1):225. doi: 10.1186/s12872-024-03892-1. PMID: 38664620Free PMC Article
Proteomic analysis of vitreous humour of eyes with diabetic macular oedema: a systematic review.
Hansen MS, Rasmussen M, Grauslund J, Subhi Y, Cehofski LJ
Acta Ophthalmol 2022 Aug;100(5):e1043-e1051. Epub 2022 May 4 doi: 10.1111/aos.15168. PMID: 35507578
Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease.
Zheng J, Zhang Y, Rasheed H, Walker V, Sugawara Y, Li J, Leng Y, Elsworth B, Wootton RE, Fang S, Yang Q, Burgess S, Haycock PC, Borges MC, Cho Y, Carnegie R, Howell A, Robinson J, Thomas LF, Brumpton BM, Hveem K, Hallan S, Franceschini N, Morris AP, Köttgen A, Pattaro C, Wuttke M, Yamamoto M, Kashihara N, Akiyama M, Kanai M, Matsuda K, Kamatani Y, Okada Y, Walters R, Millwood IY, Chen Z, Davey Smith G, Barbour S, Yu C, Åsvold BO, Zhang H, Gaunt TR
Int J Epidemiol 2022 Jan 6;50(6):1995-2010. Epub 2021 Oct 20 doi: 10.1093/ije/dyab203. PMID: 34999880Free PMC Article
Increased Endothelial Activation in Patients with Mixed Connective Tissue Disease.
Skjelland M, Zamani M, Hetlevik S, Lilleby V, Halvorsen B, Skagen K
J Stroke Cerebrovasc Dis 2020 Feb;29(2):104563. Epub 2019 Dec 9 doi: 10.1016/j.jstrokecerebrovasdis.2019.104563. PMID: 31831329
The apolipoprotein B/apolipoprotein A-I ratio as a potential marker of plasma atherogenicity.
Kaneva AM, Potolitsyna NN, Bojko ER, Odland JØ
Dis Markers 2015;2015:591454. Epub 2015 Mar 23 doi: 10.1155/2015/591454. PMID: 25852220Free PMC Article

Diagnosis

Effects on physical activity, physical fitness and well-being in a 36-months randomized controlled study, comparing a multimodal hospital-based intervention programme for primary cardiovascular prevention with usual care.
Bergum H, Grimsmo J, Anderssen SA, Klemsdal TO
BMC Cardiovasc Disord 2024 Apr 25;24(1):225. doi: 10.1186/s12872-024-03892-1. PMID: 38664620Free PMC Article
Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease.
Zheng J, Zhang Y, Rasheed H, Walker V, Sugawara Y, Li J, Leng Y, Elsworth B, Wootton RE, Fang S, Yang Q, Burgess S, Haycock PC, Borges MC, Cho Y, Carnegie R, Howell A, Robinson J, Thomas LF, Brumpton BM, Hveem K, Hallan S, Franceschini N, Morris AP, Köttgen A, Pattaro C, Wuttke M, Yamamoto M, Kashihara N, Akiyama M, Kanai M, Matsuda K, Kamatani Y, Okada Y, Walters R, Millwood IY, Chen Z, Davey Smith G, Barbour S, Yu C, Åsvold BO, Zhang H, Gaunt TR
Int J Epidemiol 2022 Jan 6;50(6):1995-2010. Epub 2021 Oct 20 doi: 10.1093/ije/dyab203. PMID: 34999880Free PMC Article
Increased Endothelial Activation in Patients with Mixed Connective Tissue Disease.
Skjelland M, Zamani M, Hetlevik S, Lilleby V, Halvorsen B, Skagen K
J Stroke Cerebrovasc Dis 2020 Feb;29(2):104563. Epub 2019 Dec 9 doi: 10.1016/j.jstrokecerebrovasdis.2019.104563. PMID: 31831329
Lipoprotein subfractions by nuclear magnetic resonance are associated with tumor characteristics in breast cancer.
Flote VG, Vettukattil R, Bathen TF, Egeland T, McTiernan A, Frydenberg H, Husøy A, Finstad SE, Lømo J, Garred Ø, Schlichting E, Wist EA, Thune I
Lipids Health Dis 2016 Mar 12;15:56. doi: 10.1186/s12944-016-0225-4. PMID: 26970778Free PMC Article
Plasma Glycine and Risk of Acute Myocardial Infarction in Patients With Suspected Stable Angina Pectoris.
Ding Y, Svingen GF, Pedersen ER, Gregory JF, Ueland PM, Tell GS, Nygård OK
J Am Heart Assoc 2015 Dec 31;5(1) doi: 10.1161/JAHA.115.002621. PMID: 26722126Free PMC Article

Therapy

Effects on physical activity, physical fitness and well-being in a 36-months randomized controlled study, comparing a multimodal hospital-based intervention programme for primary cardiovascular prevention with usual care.
Bergum H, Grimsmo J, Anderssen SA, Klemsdal TO
BMC Cardiovasc Disord 2024 Apr 25;24(1):225. doi: 10.1186/s12872-024-03892-1. PMID: 38664620Free PMC Article
Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease.
Zheng J, Zhang Y, Rasheed H, Walker V, Sugawara Y, Li J, Leng Y, Elsworth B, Wootton RE, Fang S, Yang Q, Burgess S, Haycock PC, Borges MC, Cho Y, Carnegie R, Howell A, Robinson J, Thomas LF, Brumpton BM, Hveem K, Hallan S, Franceschini N, Morris AP, Köttgen A, Pattaro C, Wuttke M, Yamamoto M, Kashihara N, Akiyama M, Kanai M, Matsuda K, Kamatani Y, Okada Y, Walters R, Millwood IY, Chen Z, Davey Smith G, Barbour S, Yu C, Åsvold BO, Zhang H, Gaunt TR
Int J Epidemiol 2022 Jan 6;50(6):1995-2010. Epub 2021 Oct 20 doi: 10.1093/ije/dyab203. PMID: 34999880Free PMC Article
Plasma Glycine and Risk of Acute Myocardial Infarction in Patients With Suspected Stable Angina Pectoris.
Ding Y, Svingen GF, Pedersen ER, Gregory JF, Ueland PM, Tell GS, Nygård OK
J Am Heart Assoc 2015 Dec 31;5(1) doi: 10.1161/JAHA.115.002621. PMID: 26722126Free PMC Article
Levels and changes of HDL cholesterol and apolipoprotein A-I in relation to risk of cardiovascular events among statin-treated patients: a meta-analysis.
Boekholdt SM, Arsenault BJ, Hovingh GK, Mora S, Pedersen TR, Larosa JC, Welch KM, Amarenco P, Demicco DA, Tonkin AM, Sullivan DR, Kirby A, Colhoun HM, Hitman GA, Betteridge DJ, Durrington PN, Clearfield MB, Downs JR, Gotto AM Jr, Ridker PM, Kastelein JJ
Circulation 2013 Oct 1;128(14):1504-12. Epub 2013 Aug 21 doi: 10.1161/CIRCULATIONAHA.113.002670. PMID: 23965489Free PMC Article
Cholesterol efflux mediators in homozygous familial hypercholesterolemia patients on low-density lipoprotein apheresis.
Nenseter MS, Narverud I, Græsdal A, Bogsrud MP, Aukrust P, Retterstøl K, Ose L, Halvorsen B, Holven KB
J Clin Lipidol 2013 Mar-Apr;7(2):109-16. Epub 2012 Aug 8 doi: 10.1016/j.jacl.2012.08.001. PMID: 23415429

Prognosis

Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease.
Zheng J, Zhang Y, Rasheed H, Walker V, Sugawara Y, Li J, Leng Y, Elsworth B, Wootton RE, Fang S, Yang Q, Burgess S, Haycock PC, Borges MC, Cho Y, Carnegie R, Howell A, Robinson J, Thomas LF, Brumpton BM, Hveem K, Hallan S, Franceschini N, Morris AP, Köttgen A, Pattaro C, Wuttke M, Yamamoto M, Kashihara N, Akiyama M, Kanai M, Matsuda K, Kamatani Y, Okada Y, Walters R, Millwood IY, Chen Z, Davey Smith G, Barbour S, Yu C, Åsvold BO, Zhang H, Gaunt TR
Int J Epidemiol 2022 Jan 6;50(6):1995-2010. Epub 2021 Oct 20 doi: 10.1093/ije/dyab203. PMID: 34999880Free PMC Article
Gestational Diabetes But Not Prepregnancy Overweight Predicts for Cardiometabolic Markers in Offspring Twenty Years Later.
Kaseva N, Vääräsmäki M, Sundvall J, Matinolli HM, Sipola M, Tikanmäki M, Heinonen K, Lano A, Wehkalampi K, Wolke D, Ruokonen A, Andersson S, Järvelin MR, Räikkönen K, Eriksson JG, Kajantie E
J Clin Endocrinol Metab 2019 Jul 1;104(7):2785-2795. doi: 10.1210/jc.2018-02743. PMID: 30835282
Plasma Glycine and Risk of Acute Myocardial Infarction in Patients With Suspected Stable Angina Pectoris.
Ding Y, Svingen GF, Pedersen ER, Gregory JF, Ueland PM, Tell GS, Nygård OK
J Am Heart Assoc 2015 Dec 31;5(1) doi: 10.1161/JAHA.115.002621. PMID: 26722126Free PMC Article
Maternal inheritance does not predict cholesterol levels in children with familial hypercholesterolemia.
Narverud I, van Lennep JR, Christensen JJ, Versmissen J, Gran JM, Iversen PO, Aukrust P, Halvorsen B, Ueland T, Ulven SM, Ose L, Veierød MB, Sijbrands E, Retterstøl K, Holven KB
Atherosclerosis 2015 Nov;243(1):155-60. Epub 2015 Sep 9 doi: 10.1016/j.atherosclerosis.2015.09.014. PMID: 26386212
The apolipoprotein B/apolipoprotein A-I ratio as a potential marker of plasma atherogenicity.
Kaneva AM, Potolitsyna NN, Bojko ER, Odland JØ
Dis Markers 2015;2015:591454. Epub 2015 Mar 23 doi: 10.1155/2015/591454. PMID: 25852220Free PMC Article

Clinical prediction guides

Effects on physical activity, physical fitness and well-being in a 36-months randomized controlled study, comparing a multimodal hospital-based intervention programme for primary cardiovascular prevention with usual care.
Bergum H, Grimsmo J, Anderssen SA, Klemsdal TO
BMC Cardiovasc Disord 2024 Apr 25;24(1):225. doi: 10.1186/s12872-024-03892-1. PMID: 38664620Free PMC Article
Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease.
Zheng J, Zhang Y, Rasheed H, Walker V, Sugawara Y, Li J, Leng Y, Elsworth B, Wootton RE, Fang S, Yang Q, Burgess S, Haycock PC, Borges MC, Cho Y, Carnegie R, Howell A, Robinson J, Thomas LF, Brumpton BM, Hveem K, Hallan S, Franceschini N, Morris AP, Köttgen A, Pattaro C, Wuttke M, Yamamoto M, Kashihara N, Akiyama M, Kanai M, Matsuda K, Kamatani Y, Okada Y, Walters R, Millwood IY, Chen Z, Davey Smith G, Barbour S, Yu C, Åsvold BO, Zhang H, Gaunt TR
Int J Epidemiol 2022 Jan 6;50(6):1995-2010. Epub 2021 Oct 20 doi: 10.1093/ije/dyab203. PMID: 34999880Free PMC Article
Children with familial hypercholesterolemia display changes in LDL and HDL function: A cross-sectional study.
Christensen JJ, Narverud I, Ruuth M, Heier M, Jauhiainen M, Ulven SM, Bogsrud MP, Kovanen PT, Halvorsen B, Oda MN, Wium C, Retterstøl K, Öörni K, Holven KB
J Intern Med 2021 Nov;290(5):1083-1097. doi: 10.1111/joim.13383. PMID: 34506681
Gestational Diabetes But Not Prepregnancy Overweight Predicts for Cardiometabolic Markers in Offspring Twenty Years Later.
Kaseva N, Vääräsmäki M, Sundvall J, Matinolli HM, Sipola M, Tikanmäki M, Heinonen K, Lano A, Wehkalampi K, Wolke D, Ruokonen A, Andersson S, Järvelin MR, Räikkönen K, Eriksson JG, Kajantie E
J Clin Endocrinol Metab 2019 Jul 1;104(7):2785-2795. doi: 10.1210/jc.2018-02743. PMID: 30835282
The apolipoprotein B/apolipoprotein A-I ratio as a potential marker of plasma atherogenicity.
Kaneva AM, Potolitsyna NN, Bojko ER, Odland JØ
Dis Markers 2015;2015:591454. Epub 2015 Mar 23 doi: 10.1155/2015/591454. PMID: 25852220Free PMC Article

Recent systematic reviews

Proteomic analysis of vitreous humour of eyes with diabetic macular oedema: a systematic review.
Hansen MS, Rasmussen M, Grauslund J, Subhi Y, Cehofski LJ
Acta Ophthalmol 2022 Aug;100(5):e1043-e1051. Epub 2022 May 4 doi: 10.1111/aos.15168. PMID: 35507578

Supplemental Content

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