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Long QT syndrome, bradycardia-induced

MedGen UID:
864685
•Concept ID:
C4016248
•
Finding
Synonym: LONG QT SYNDROME, BRADYCARDIA-INDUCED
 
OMIM®: 152427

Professional guidelines

PubMed

Contribution of a KCNH2 variant in genotyped long QT syndrome: Romano-Ward syndrome under double mutations and acquired long QT syndrome under heterozygote.
Fujii Y, Matsumoto Y, Hayashi K, Ding WG, Tomita Y, Fukumoto D, Wada Y, Ichikawa M, Sonoda K, Ozawa J, Makiyama T, Ohno S, Yamagishi M, Matsuura H, Horie M, Itoh H
J Cardiol 2017 Jul;70(1):74-79. Epub 2016 Nov 3 doi: 10.1016/j.jjcc.2016.09.010. PMID: 27816319

Recent clinical studies

Etiology

Electrocardiographic predictors of bradycardia-induced torsades de pointes in patients with acquired atrioventricular block.
Cho MS, Nam GB, Kim YG, Hwang KW, Kim YR, Choi H, Kim SH, Rhee KS, Kim NJ, Kim JS, Kim J, Choi KJ, Kim YH
Heart Rhythm 2015 Mar;12(3):498-505. Epub 2014 Nov 18 doi: 10.1016/j.hrthm.2014.11.018. PMID: 25460857
Long QT syndrome complicating atrioventricular block: arrhythmogenic effects of cardiac memory.
Rosso R, Adler A, Strasberg B, Guevara-Valdivia ME, Somani R, Baranchuk A, Halkin A, Márquez MF, Scheinman M, Steinvil A, Belhassen B, Kazatsker M, Katz A, Viskin S
Circ Arrhythm Electrophysiol 2014 Dec;7(6):1129-35. Epub 2014 Oct 13 doi: 10.1161/CIRCEP.114.002085. PMID: 25313259
Is gender a risk factor for adverse drug reactions? The example of drug-induced long QT syndrome.
Drici MD, Clément N
Drug Saf 2001;24(8):575-85. doi: 10.2165/00002018-200124080-00002. PMID: 11480490
Increased propensity of women to develop torsades de pointes during complete heart block.
Kawasaki R, Machado C, Reinoehl J, Fromm B, Baga JJ, Steinman RT, Lehmann MH
J Cardiovasc Electrophysiol 1995 Nov;6(11):1032-8. doi: 10.1111/j.1540-8167.1995.tb00380.x. PMID: 8589872

Diagnosis

Contribution of a KCNH2 variant in genotyped long QT syndrome: Romano-Ward syndrome under double mutations and acquired long QT syndrome under heterozygote.
Fujii Y, Matsumoto Y, Hayashi K, Ding WG, Tomita Y, Fukumoto D, Wada Y, Ichikawa M, Sonoda K, Ozawa J, Makiyama T, Ohno S, Yamagishi M, Matsuura H, Horie M, Itoh H
J Cardiol 2017 Jul;70(1):74-79. Epub 2016 Nov 3 doi: 10.1016/j.jjcc.2016.09.010. PMID: 27816319
Electrocardiographic predictors of bradycardia-induced torsades de pointes in patients with acquired atrioventricular block.
Cho MS, Nam GB, Kim YG, Hwang KW, Kim YR, Choi H, Kim SH, Rhee KS, Kim NJ, Kim JS, Kim J, Choi KJ, Kim YH
Heart Rhythm 2015 Mar;12(3):498-505. Epub 2014 Nov 18 doi: 10.1016/j.hrthm.2014.11.018. PMID: 25460857
Long QT syndrome complicating atrioventricular block: arrhythmogenic effects of cardiac memory.
Rosso R, Adler A, Strasberg B, Guevara-Valdivia ME, Somani R, Baranchuk A, Halkin A, Márquez MF, Scheinman M, Steinvil A, Belhassen B, Kazatsker M, Katz A, Viskin S
Circ Arrhythm Electrophysiol 2014 Dec;7(6):1129-35. Epub 2014 Oct 13 doi: 10.1161/CIRCEP.114.002085. PMID: 25313259
Torsade de pointes associated with bradycardia and takotsubo cardiomyopathy.
Kurisu S, Inoue I, Kawagoe T, Ishihara M, Shimatani Y, Nakama Y, Ohkawa K, Maruhashi T, Kagawa E, Dai K, Aokage T
Can J Cardiol 2008 Aug;24(8):640-2. doi: 10.1016/s0828-282x(08)70653-6. PMID: 18685745Free PMC Article
Assessing QT prolongation in conscious dogs: validation of a beat-to-beat method.
Fossa AA
Pharmacol Ther 2008 May;118(2):231-8. Epub 2008 Mar 7 doi: 10.1016/j.pharmthera.2008.02.006. PMID: 18420278

Therapy

Is gender a risk factor for adverse drug reactions? The example of drug-induced long QT syndrome.
Drici MD, Clément N
Drug Saf 2001;24(8):575-85. doi: 10.2165/00002018-200124080-00002. PMID: 11480490

Prognosis

Electrocardiographic predictors of bradycardia-induced torsades de pointes in patients with acquired atrioventricular block.
Cho MS, Nam GB, Kim YG, Hwang KW, Kim YR, Choi H, Kim SH, Rhee KS, Kim NJ, Kim JS, Kim J, Choi KJ, Kim YH
Heart Rhythm 2015 Mar;12(3):498-505. Epub 2014 Nov 18 doi: 10.1016/j.hrthm.2014.11.018. PMID: 25460857
Long QT syndrome complicating atrioventricular block: arrhythmogenic effects of cardiac memory.
Rosso R, Adler A, Strasberg B, Guevara-Valdivia ME, Somani R, Baranchuk A, Halkin A, Márquez MF, Scheinman M, Steinvil A, Belhassen B, Kazatsker M, Katz A, Viskin S
Circ Arrhythm Electrophysiol 2014 Dec;7(6):1129-35. Epub 2014 Oct 13 doi: 10.1161/CIRCEP.114.002085. PMID: 25313259

Clinical prediction guides

Electrocardiographic predictors of bradycardia-induced torsades de pointes in patients with acquired atrioventricular block.
Cho MS, Nam GB, Kim YG, Hwang KW, Kim YR, Choi H, Kim SH, Rhee KS, Kim NJ, Kim JS, Kim J, Choi KJ, Kim YH
Heart Rhythm 2015 Mar;12(3):498-505. Epub 2014 Nov 18 doi: 10.1016/j.hrthm.2014.11.018. PMID: 25460857
Long QT syndrome complicating atrioventricular block: arrhythmogenic effects of cardiac memory.
Rosso R, Adler A, Strasberg B, Guevara-Valdivia ME, Somani R, Baranchuk A, Halkin A, Márquez MF, Scheinman M, Steinvil A, Belhassen B, Kazatsker M, Katz A, Viskin S
Circ Arrhythm Electrophysiol 2014 Dec;7(6):1129-35. Epub 2014 Oct 13 doi: 10.1161/CIRCEP.114.002085. PMID: 25313259
Role of HCN4 channel in preventing ventricular arrhythmia.
Ueda K, Hirano Y, Higashiuesato Y, Aizawa Y, Hayashi T, Inagaki N, Tana T, Ohya Y, Takishita S, Muratani H, Hiraoka M, Kimura A
J Hum Genet 2009 Feb;54(2):115-21. Epub 2009 Jan 23 doi: 10.1038/jhg.2008.16. PMID: 19165230
Assessing QT prolongation in conscious dogs: validation of a beat-to-beat method.
Fossa AA
Pharmacol Ther 2008 Aug;119(2):133-40. doi: 10.1016/j.pharmthera.2008.02.013. PMID: 18938261
Assessing QT prolongation in conscious dogs: validation of a beat-to-beat method.
Fossa AA
Pharmacol Ther 2008 May;118(2):231-8. Epub 2008 Mar 7 doi: 10.1016/j.pharmthera.2008.02.006. PMID: 18420278

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