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Hypertension, salt-sensitive essential, susceptibility to

MedGen UID:
854224
•Concept ID:
C3837651
•
Disease or Syndrome
Synonym: HYPERTENSION, SALT-SENSITIVE ESSENTIAL, SUSCEPTIBILITY TO
 
OMIM®: 102680; 605325

Recent clinical studies

Etiology

Genes involved in vasoconstriction and vasodilation system affect salt-sensitive hypertension.
Citterio L, Simonini M, Zagato L, Salvi E, Delli Carpini S, Lanzani C, Messaggio E, Casamassima N, Frau F, D'Avila F, Cusi D, Barlassina C, Manunta P
PLoS One 2011 May 9;6(5):e19620. doi: 10.1371/journal.pone.0019620. PMID: 21573014Free PMC Article
Computational analysis of candidate disease genes and variants for salt-sensitive hypertension in indigenous Southern Africans.
Tiffin N, Meintjes A, Ramesar R, Bajic VB, Rayner B
PLoS One 2010 Sep 27;5(9):e12989. doi: 10.1371/journal.pone.0012989. PMID: 20886000Free PMC Article
WNK kinases and essential hypertension.
Huang CL, Kuo E, Toto RD
Curr Opin Nephrol Hypertens 2008 Mar;17(2):133-7. doi: 10.1097/MNH.0b013e3282f4e4fd. PMID: 18277144
Nephron number and renal risk in hypertension and diabetes.
Gross ML, Amann K, Ritz E
J Am Soc Nephrol 2005 Mar;16 Suppl 1:S27-9. doi: 10.1681/asn.2004110967. PMID: 15938029
Salt and hypertension at the close of the millenium.
Luft FC
Wien Klin Wochenschr 1998 Jul 31;110(13-14):459-66. PMID: 9746958

Diagnosis

Genes involved in vasoconstriction and vasodilation system affect salt-sensitive hypertension.
Citterio L, Simonini M, Zagato L, Salvi E, Delli Carpini S, Lanzani C, Messaggio E, Casamassima N, Frau F, D'Avila F, Cusi D, Barlassina C, Manunta P
PLoS One 2011 May 9;6(5):e19620. doi: 10.1371/journal.pone.0019620. PMID: 21573014Free PMC Article
WNK kinases and essential hypertension.
Huang CL, Kuo E, Toto RD
Curr Opin Nephrol Hypertens 2008 Mar;17(2):133-7. doi: 10.1097/MNH.0b013e3282f4e4fd. PMID: 18277144
Nephron number and renal risk in hypertension and diabetes.
Gross ML, Amann K, Ritz E
J Am Soc Nephrol 2005 Mar;16 Suppl 1:S27-9. doi: 10.1681/asn.2004110967. PMID: 15938029
Salt and hypertension at the close of the millenium.
Luft FC
Wien Klin Wochenschr 1998 Jul 31;110(13-14):459-66. PMID: 9746958
Glomeruli and blood pressure. Less of one, more the other?
Brenner BM, Garcia DL, Anderson S
Am J Hypertens 1988 Oct;1(4 Pt 1):335-47. doi: 10.1093/ajh/1.4.335. PMID: 3063284

Therapy

Genes involved in vasoconstriction and vasodilation system affect salt-sensitive hypertension.
Citterio L, Simonini M, Zagato L, Salvi E, Delli Carpini S, Lanzani C, Messaggio E, Casamassima N, Frau F, D'Avila F, Cusi D, Barlassina C, Manunta P
PLoS One 2011 May 9;6(5):e19620. doi: 10.1371/journal.pone.0019620. PMID: 21573014Free PMC Article
WNK kinases and essential hypertension.
Huang CL, Kuo E, Toto RD
Curr Opin Nephrol Hypertens 2008 Mar;17(2):133-7. doi: 10.1097/MNH.0b013e3282f4e4fd. PMID: 18277144
Role of sodium and volume in the pathogenesis of hypertension in dialysis patients. Reflections on pathophysiological mechanisms.
Kooman JP, van der Sande FM, Leunissen KM
Blood Purif 2004;22(1):55-9. doi: 10.1159/000074924. PMID: 14732812
Salt and hypertension at the close of the millenium.
Luft FC
Wien Klin Wochenschr 1998 Jul 31;110(13-14):459-66. PMID: 9746958
Inverse regulation of alpha-2 and beta-2 adrenoceptors in salt-sensitive hypertension: an hypothesis.
Skrabal F, Kotanko P, Luft FC
Life Sci 1989;45(22):2061-76. doi: 10.1016/0024-3205(89)90071-4. PMID: 2557514

Prognosis

Interaction of alpha(1)-Na,K-ATPase and Na,K,2Cl-cotransporter genes in human essential hypertension.
Glorioso N, Filigheddu F, Troffa C, Soro A, Parpaglia PP, Tsikoudakis A, Myers RH, Herrera VL, Ruiz-Opazo N
Hypertension 2001 Aug;38(2):204-9. doi: 10.1161/01.hyp.38.2.204. PMID: 11509477
The interrelationships among filtration surface area, blood pressure, and chronic renal disease.
Brenner BM, Anderson S
J Cardiovasc Pharmacol 1992;19 Suppl 6:S1-7. doi: 10.1097/00005344-199219006-00002. PMID: 1382155
Glomeruli and blood pressure. Less of one, more the other?
Brenner BM, Garcia DL, Anderson S
Am J Hypertens 1988 Oct;1(4 Pt 1):335-47. doi: 10.1093/ajh/1.4.335. PMID: 3063284

Clinical prediction guides

Salt-sensitive men show reduced heart rate variability, lower norepinephrine and enhanced cortisol during mental stress.
Weber CS, Thayer JF, Rudat M, Sharma AM, Perschel FH, Buchholz K, Deter HC
J Hum Hypertens 2008 Jun;22(6):423-31. Epub 2008 Mar 13 doi: 10.1038/jhh.2008.11. PMID: 18337758
Role of sodium and volume in the pathogenesis of hypertension in dialysis patients. Reflections on pathophysiological mechanisms.
Kooman JP, van der Sande FM, Leunissen KM
Blood Purif 2004;22(1):55-9. doi: 10.1159/000074924. PMID: 14732812
Interaction of alpha(1)-Na,K-ATPase and Na,K,2Cl-cotransporter genes in human essential hypertension.
Glorioso N, Filigheddu F, Troffa C, Soro A, Parpaglia PP, Tsikoudakis A, Myers RH, Herrera VL, Ruiz-Opazo N
Hypertension 2001 Aug;38(2):204-9. doi: 10.1161/01.hyp.38.2.204. PMID: 11509477
Inverse regulation of alpha-2 and beta-2 adrenoceptors in salt-sensitive hypertension: an hypothesis.
Skrabal F, Kotanko P, Luft FC
Life Sci 1989;45(22):2061-76. doi: 10.1016/0024-3205(89)90071-4. PMID: 2557514
Glomeruli and blood pressure. Less of one, more the other?
Brenner BM, Garcia DL, Anderson S
Am J Hypertens 1988 Oct;1(4 Pt 1):335-47. doi: 10.1093/ajh/1.4.335. PMID: 3063284

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