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Pathergy reaction

MedGen UID:
1715810
•Concept ID:
C3804968
•
Sign or Symptom
SNOMED CT: Pathergy reaction (844581009)

Professional guidelines

PubMed

Validation of the classification criteria commonly used in Korea and a modified set of preliminary criteria for Behçet's disease: a multi-center study.
Chang HK, Lee SS, Bai HJ, Lee YW, Yoon BY, Lee CH, Lee YH, Song GG, Chung WT, Lee SW, Choe JY, Kim CG, Chang DK
Clin Exp Rheumatol 2004 Jul-Aug;22(4 Suppl 34):S21-6. PMID: 15515778

Recent clinical studies

Etiology

Clinical features of Behçet's disease and prediction of the use of biologics in 488 cases: a single tertiary center study.
Çakan ZK, Yağız B, Pehlivan Y
Rheumatol Int 2023 Nov;43(11):2089-2097. Epub 2023 Aug 22 doi: 10.1007/s00296-023-05416-0. PMID: 37604938
Improved sensitivity of the skin pathergy test with polysaccharide pneumococcal vaccine antigens in the diagnosis of Behçet disease.
Deniz R, Emrence Z, Yalçınkaya Y, Artım Esen B, İnanç M, Öcal ML, Gül A
Rheumatology (Oxford) 2023 May 2;62(5):1903-1909. doi: 10.1093/rheumatology/keac543. PMID: 36171681
Coronary involvement in patients with Behçet's disease.
Chen H, Zhang Y, Li C, Wu W, Liu J, Zhang F, Zheng W
Clin Rheumatol 2019 Oct;38(10):2835-2841. Epub 2019 Jun 28 doi: 10.1007/s10067-019-04640-z. PMID: 31273636
The skin pathergy test: innately useful?
Varol A, Seifert O, Anderson CD
Arch Dermatol Res 2010 Apr;302(3):155-68. Epub 2009 Dec 12 doi: 10.1007/s00403-009-1008-9. PMID: 20012749
Pathergy reaction in Behçet's disease: lack of correlation with mucocutaneous manifestations and systemic disease expression.
Krause I, Molad Y, Mitrani M, Weinberger A
Clin Exp Rheumatol 2000 Jan-Feb;18(1):71-4. PMID: 10728447

Diagnosis

Histopathological comparison of pathergy positive and negative areas of newly diagnosed Behçet patients.
Temiz SA, Balevi S, Oltulu P, Ozer I
Int J Clin Pract 2021 Dec;75(12):e14994. Epub 2021 Nov 6 doi: 10.1111/ijcp.14994. PMID: 34710265
The Pathergy Test as a Diagnostic Tool.
Kutlubay Z, Tüzün Y, Wolf R
Skinmed 2017;15(2):97-104. Epub 2017 Apr 1 PMID: 28528602
Behçet syndrome: is it one condition?
Yazici H, Ugurlu S, Seyahi E
Clin Rev Allergy Immunol 2012 Dec;43(3):275-80. doi: 10.1007/s12016-012-8319-x. PMID: 22674015
The skin pathergy test: innately useful?
Varol A, Seifert O, Anderson CD
Arch Dermatol Res 2010 Apr;302(3):155-68. Epub 2009 Dec 12 doi: 10.1007/s00403-009-1008-9. PMID: 20012749
Mucocutaneous lesions of Behcet's disease.
Alpsoy E, Zouboulis CC, Ehrlich GE
Yonsei Med J 2007 Aug 31;48(4):573-85. doi: 10.3349/ymj.2007.48.4.573. PMID: 17722228Free PMC Article

Therapy

Laser-Induced Koebner-Related Skin Reactions: A Clinical Overview.
Karampinis E, Georgopoulou KE, Goudouras G, Lianou V, Kampra E, Roussaki Schulze AV, Zafiriou E
Medicina (Kaunas) 2024 Jul 20;60(7) doi: 10.3390/medicina60071177. PMID: 39064606Free PMC Article
Case Report: Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne: A Single-Center Experience and Literature Review.
Wang Y, Wu N, Yu K, Shen M
Front Immunol 2021;12:735851. Epub 2021 Oct 22 doi: 10.3389/fimmu.2021.735851. PMID: 34745107Free PMC Article
A novel case of renal pathergy reaction in a Behçet's disease patient complicated by IgA vasculitis.
Higashihara T, Okada A, Kusano T, Ishigaki K, Shimizu A, Takano H
BMC Nephrol 2017 Jan 28;18(1):40. doi: 10.1186/s12882-017-0451-7. PMID: 28129738Free PMC Article
Behçet's syndrome and micro-organisms.
Hatemi G, Yazici H
Best Pract Res Clin Rheumatol 2011 Jun;25(3):389-406. doi: 10.1016/j.berh.2011.05.002. PMID: 22100288
Comparison of argon laser photocoagulation-induced cutaneous inflammation and skin pathergy test in Behçet's disease.
Sayarlioglu M, Calka O, Cinal A, Sayarlioglu H, Akdeniz N, Topcu N, Durmus AC, Demirok A, Ilhan B, Gul A
Clin Rheumatol 2010 Jan;29(1):59-63. Epub 2009 Oct 11 doi: 10.1007/s10067-009-1294-9. PMID: 19821068

Prognosis

Clinical features of Behçet's disease and prediction of the use of biologics in 488 cases: a single tertiary center study.
Çakan ZK, Yağız B, Pehlivan Y
Rheumatol Int 2023 Nov;43(11):2089-2097. Epub 2023 Aug 22 doi: 10.1007/s00296-023-05416-0. PMID: 37604938
Behçet's syndrome and micro-organisms.
Hatemi G, Yazici H
Best Pract Res Clin Rheumatol 2011 Jun;25(3):389-406. doi: 10.1016/j.berh.2011.05.002. PMID: 22100288
The skin pathergy test: innately useful?
Varol A, Seifert O, Anderson CD
Arch Dermatol Res 2010 Apr;302(3):155-68. Epub 2009 Dec 12 doi: 10.1007/s00403-009-1008-9. PMID: 20012749
Behçet's disease in southern Chinese patients.
Mok CC, Cheung TC, Ho CT, Lee KW, Lau CS, Wong RW
J Rheumatol 2002 Aug;29(8):1689-93. PMID: 12180731
Pathergy reaction in Behçet's disease: lack of correlation with mucocutaneous manifestations and systemic disease expression.
Krause I, Molad Y, Mitrani M, Weinberger A
Clin Exp Rheumatol 2000 Jan-Feb;18(1):71-4. PMID: 10728447

Clinical prediction guides

Clinical features of Behçet's disease and prediction of the use of biologics in 488 cases: a single tertiary center study.
Çakan ZK, Yağız B, Pehlivan Y
Rheumatol Int 2023 Nov;43(11):2089-2097. Epub 2023 Aug 22 doi: 10.1007/s00296-023-05416-0. PMID: 37604938
Improved sensitivity of the skin pathergy test with polysaccharide pneumococcal vaccine antigens in the diagnosis of Behçet disease.
Deniz R, Emrence Z, Yalçınkaya Y, Artım Esen B, İnanç M, Öcal ML, Gül A
Rheumatology (Oxford) 2023 May 2;62(5):1903-1909. doi: 10.1093/rheumatology/keac543. PMID: 36171681
Behçet syndrome: is it one condition?
Yazici H, Ugurlu S, Seyahi E
Clin Rev Allergy Immunol 2012 Dec;43(3):275-80. doi: 10.1007/s12016-012-8319-x. PMID: 22674015
The skin pathergy test: innately useful?
Varol A, Seifert O, Anderson CD
Arch Dermatol Res 2010 Apr;302(3):155-68. Epub 2009 Dec 12 doi: 10.1007/s00403-009-1008-9. PMID: 20012749
The clinical significance of a pathergy reaction in patients with Behcet's disease.
Chang HK, Cheon KS
J Korean Med Sci 2002 Jun;17(3):371-4. doi: 10.3346/jkms.2002.17.3.371. PMID: 12068142Free PMC Article

Recent systematic reviews

Case Report: Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne: A Single-Center Experience and Literature Review.
Wang Y, Wu N, Yu K, Shen M
Front Immunol 2021;12:735851. Epub 2021 Oct 22 doi: 10.3389/fimmu.2021.735851. PMID: 34745107Free PMC Article

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