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Primary Hyperthyroidism

MedGen UID:
811409
•Concept ID:
C3714618
•
Disease or Syndrome
Synonym: Hyperthyroidism, Primary

Definition

Overproduction of thyroid hormone due to a disorder originating within the thyroid gland. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPrimary Hyperthyroidism

Professional guidelines

PubMed

Diagnosis and treatment of TSH-secreting adenomas: review of a longtime experience in a reference center.
Nazato DM, Abucham J
J Endocrinol Invest 2018 Apr;41(4):447-454. Epub 2017 Oct 11 doi: 10.1007/s40618-017-0770-3. PMID: 29022276
Clinical and morphological characteristics, diagnostic criteria, and outcomes of surgical treatment of TSH-secreting pituitary adenomas.
Astaf'eva LI, Kadashev BA, Shishkina LV, Kalinin PL, Fomichev DV, Kutin MA, Aref'eva IA, Dzeranova LK, Sidneva YG, Klochkova IS, Rotin DL
Zh Vopr Neirokhir Im N N Burdenko 2016;80(6):24-35. doi: 10.17116/neiro201680624-35. PMID: 28139570
Primary hyperthyroidism--diagnosis and treatment. Indications and contraindications for radioiodine therapy.
Gurgul E, Sowinski J
Nucl Med Rev Cent East Eur 2011;14(1):29-32. PMID: 21751169

Recent clinical studies

Etiology

Acute effect of propranolol on resting energy expenditure in hyperthyroid patients.
Senn JR, Löliger RC, Fischer JGW, Bur F, Maushart CI, Betz MJ
Front Endocrinol (Lausanne) 2022;13:1026998. Epub 2023 Jan 19 doi: 10.3389/fendo.2022.1026998. PMID: 36743920Free PMC Article
Risk of perioperative thyroid storm in hyperthyroid patients: a systematic review.
de Mul N, Damstra J, Nieveen van Dijkum EJM, Fischli S, Kalkman CJ, Schellekens WM, Immink RV
Br J Anaesth 2021 Dec;127(6):879-889. Epub 2021 Aug 11 doi: 10.1016/j.bja.2021.06.043. PMID: 34389171
Concomitant thyroid disease in patients operated for primary hyperparathyroidism.
Libánský P, Adámek S, Broulík P, Fialová M, Šedý J, Tvrdoň J, Vaculová M, Lischke R
Rozhl Chir 2021 Winter;100(1):17-20. doi: 10.33699/PIS.2021.100.1.17-20. PMID: 33691418
Genetic hypercalcemia.
Cormier C
Joint Bone Spine 2019 Jul;86(4):459-466. Epub 2018 Oct 6 doi: 10.1016/j.jbspin.2018.10.001. PMID: 30300686
Renal lithiasis in patients with primary hyperparathyroidism. Evolution and treatment.
Valle Díaz de la Guardia F, Arrabal Martín M, Arrabal Polo MA, Quirosa Flores S, Miján Ortiz JL, Zuluaga Gómez A
Arch Esp Urol 2010 Jan-Feb;63(1):32-40. PMID: 20157217

Diagnosis

Assessment of Thyroid Dysfunction During Different Trimester of Pregnancy.
Prajapati S, Prajapati G, Shrestha V, Shrestha S
J Nepal Health Res Counc 2023 Jul 20;20(4):830-833. doi: 10.33314/jnhrc.v20i4.3712. PMID: 37489662
Assessment of Thyroid Function in Patients With Alkaptonuria.
Avadhanula S, Introne WJ, Auh S, Soldin SJ, Stolze B, Regier D, Ciccone C, Hannah-Shmouni F, Filie AC, Burman KD, Klubo-Gwiezdzinska J
JAMA Netw Open 2020 Mar 2;3(3):e201357. doi: 10.1001/jamanetworkopen.2020.1357. PMID: 32202644Free PMC Article
Genetic hypercalcemia.
Cormier C
Joint Bone Spine 2019 Jul;86(4):459-466. Epub 2018 Oct 6 doi: 10.1016/j.jbspin.2018.10.001. PMID: 30300686
Primary hyperthyroidism--diagnosis and treatment. Indications and contraindications for radioiodine therapy.
Gurgul E, Sowinski J
Nucl Med Rev Cent East Eur 2011;14(1):29-32. PMID: 21751169
Central hyperthyroidism.
McDermott MT, Ridgway EC
Endocrinol Metab Clin North Am 1998 Mar;27(1):187-203. doi: 10.1016/s0889-8529(05)70306-6. PMID: 9534036

Therapy

Acute effect of propranolol on resting energy expenditure in hyperthyroid patients.
Senn JR, Löliger RC, Fischer JGW, Bur F, Maushart CI, Betz MJ
Front Endocrinol (Lausanne) 2022;13:1026998. Epub 2023 Jan 19 doi: 10.3389/fendo.2022.1026998. PMID: 36743920Free PMC Article
Risk of perioperative thyroid storm in hyperthyroid patients: a systematic review.
de Mul N, Damstra J, Nieveen van Dijkum EJM, Fischli S, Kalkman CJ, Schellekens WM, Immink RV
Br J Anaesth 2021 Dec;127(6):879-889. Epub 2021 Aug 11 doi: 10.1016/j.bja.2021.06.043. PMID: 34389171
Primary hyperthyroidism--diagnosis and treatment. Indications and contraindications for radioiodine therapy.
Gurgul E, Sowinski J
Nucl Med Rev Cent East Eur 2011;14(1):29-32. PMID: 21751169
Hyperthyroidism (primary).
Nygaard B
BMJ Clin Evid 2010 Jul 19;2010 PMID: 21418670Free PMC Article
Hyperthyroidism (primary).
Nygaard B
BMJ Clin Evid 2008 Mar 25;2008 PMID: 19450325Free PMC Article

Prognosis

Thyroid dysfunctions in adult patients after allogeneic hematopoietic stem cell transplantation.
Ataca Atilla P, Akkus E, Atilla E, Gokmen N, Civriz Bozdag S, Kurt Yuksel M, Toprak SK, Baskal N, Akan H, Demirer T, Topcuoglu P, Arslan O, Ilhan O, Ozcan M, Beksac M, Gurman G
Clin Transplant 2020 Oct;34(10):e14049. Epub 2020 Aug 29 doi: 10.1111/ctr.14049. PMID: 32713042
Genetic hypercalcemia.
Cormier C
Joint Bone Spine 2019 Jul;86(4):459-466. Epub 2018 Oct 6 doi: 10.1016/j.jbspin.2018.10.001. PMID: 30300686
Hyperthyroidism (primary).
Nygaard B
BMJ Clin Evid 2010 Jul 19;2010 PMID: 21418670Free PMC Article
Hyperthyroidism (primary).
Nygaard B
BMJ Clin Evid 2008 Mar 25;2008 PMID: 19450325Free PMC Article
Thyrotropin receptor autoantibodies (TSHRAbs): epitopes, origins and clinical significance.
Kohn LD, Harii N
Autoimmunity 2003 Sep-Nov;36(6-7):331-7. doi: 10.1080/08916930310001604199. PMID: 14669940

Clinical prediction guides

Thyroid Hormones Regulate the Thermoregulatory Mechanisms of the Body: Review.
Filfilan WM
Pak J Biol Sci 2023 Aug;26(9):453-457. doi: 10.3923/pjbs.2023.453.457. PMID: 38044694
Effects of thyroid hormones on thermogenesis and energy partitioning.
Iwen KA, Oelkrug R, Brabant G
J Mol Endocrinol 2018 Apr;60(3):R157-R170. Epub 2018 Feb 6 doi: 10.1530/JME-17-0319. PMID: 29434028
Primary hyperthyroidism--diagnosis and treatment. Indications and contraindications for radioiodine therapy.
Gurgul E, Sowinski J
Nucl Med Rev Cent East Eur 2011;14(1):29-32. PMID: 21751169
Hyperthyroidism (primary).
Nygaard B
BMJ Clin Evid 2010 Jul 19;2010 PMID: 21418670Free PMC Article
Hyperthyroidism (primary).
Nygaard B
BMJ Clin Evid 2008 Mar 25;2008 PMID: 19450325Free PMC Article

Recent systematic reviews

Risk of perioperative thyroid storm in hyperthyroid patients: a systematic review.
de Mul N, Damstra J, Nieveen van Dijkum EJM, Fischli S, Kalkman CJ, Schellekens WM, Immink RV
Br J Anaesth 2021 Dec;127(6):879-889. Epub 2021 Aug 11 doi: 10.1016/j.bja.2021.06.043. PMID: 34389171
Hyperthyroidism (primary).
Nygaard B
BMJ Clin Evid 2010 Jul 19;2010 PMID: 21418670Free PMC Article
Hyperthyroidism (primary).
Nygaard B
BMJ Clin Evid 2008 Mar 25;2008 PMID: 19450325Free PMC Article

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