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Staphylococcal toxic-shock syndrome

MedGen UID:
811401
•Concept ID:
C3714602
•
Disease or Syndrome
Synonyms: Bacterial toxic-shock syndrome; Shock, Toxic
SNOMED CT: Staphylococcal toxic shock syndrome (240450004)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
•Concept ID:
CN307044
•
Finding
Source: Orphanet
clinical entity without genetic inheritance.
See: This record
Not genetically inherited (Orphanet)
 
Monarch Initiative: MONDO:0020545
Orphanet: ORPHA99919

Definition

Staphylococcal toxic shock syndrome (staphylococcal TSS) is an acute disease mediated by the production of superantigenic toxins, characterized by high fever, skin rash followed by skin peeling, hypotension, vomiting, diarrhea and potentially leading to multisystem organ failure and caused by a <i>Staphylococcus aureus</i> bacterial infection. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVStaphylococcal toxic-shock syndrome

Professional guidelines

PubMed

Optimum treatment of staphylococcal infections.
Turnidge J, Grayson ML
Drugs 1993 Mar;45(3):353-66. doi: 10.2165/00003495-199345030-00004. PMID: 7682906

Recent clinical studies

Etiology

Clinical and Molecular Epidemiology of Staphylococcal Toxic Shock Syndrome in the United Kingdom.
Sharma H, Smith D, Turner CE, Game L, Pichon B, Hope R, Hill R, Kearns A, Sriskandan S
Emerg Infect Dis 2018 Feb;24(2):258-66. doi: 10.3201/eid2402.170606. PMID: 29350159Free PMC Article
Toxic shock syndrome.
Dass R, Nishad P, Singhi S
Indian J Pediatr 2004 May;71(5):433-5. doi: 10.1007/BF02725635. PMID: 15163875
Infectious exanthems and unusual infections.
Vincent JM, Demers DM, Bass JW
Adolesc Med 2000 Jun;11(2):327-58. PMID: 10916128
The toxic shock syndromes.
Stevens DL
Infect Dis Clin North Am 1996 Dec;10(4):727-46. doi: 10.1016/s0891-5520(05)70324-x. PMID: 8958166
Staphylococcal toxin-mediated syndromes in childhood.
Resnick SD
Semin Dermatol 1992 Mar;11(1):11-8. PMID: 1550711

Diagnosis

Staphylococcal toxic shock syndrome.
Barros Pinto MP
J Hematop 2023 Sep;16(3):189-190. Epub 2023 May 11 doi: 10.1007/s12308-023-00547-6. PMID: 38175396
Clinical and Molecular Epidemiology of Staphylococcal Toxic Shock Syndrome in the United Kingdom.
Sharma H, Smith D, Turner CE, Game L, Pichon B, Hope R, Hill R, Kearns A, Sriskandan S
Emerg Infect Dis 2018 Feb;24(2):258-66. doi: 10.3201/eid2402.170606. PMID: 29350159Free PMC Article
Toxic shock syndrome.
Dass R, Nishad P, Singhi S
Indian J Pediatr 2004 May;71(5):433-5. doi: 10.1007/BF02725635. PMID: 15163875
Staphylococcal toxic shock syndrome. Suspicion and prevention are keys to control.
Issa NC, Thompson RL
Postgrad Med 2001 Oct;110(4):55-6, 59-62. doi: 10.3810/pgm.2001.10.1045. PMID: 11675982
The toxic shock syndromes.
Stevens DL
Infect Dis Clin North Am 1996 Dec;10(4):727-46. doi: 10.1016/s0891-5520(05)70324-x. PMID: 8958166

Therapy

Epithelial proinflammatory response and curcumin-mediated protection from staphylococcal toxic shock syndrome toxin-1.
Schaefers MM, Breshears LM, Anderson MJ, Lin YC, Grill AE, Panyam J, Southern PJ, Schlievert PM, Peterson ML
PLoS One 2012;7(3):e32813. Epub 2012 Mar 14 doi: 10.1371/journal.pone.0032813. PMID: 22431984Free PMC Article
Toxic shock syndrome.
Dass R, Nishad P, Singhi S
Indian J Pediatr 2004 May;71(5):433-5. doi: 10.1007/BF02725635. PMID: 15163875
The toxic shock syndromes.
Stevens DL
Infect Dis Clin North Am 1996 Dec;10(4):727-46. doi: 10.1016/s0891-5520(05)70324-x. PMID: 8958166
Optimum treatment of staphylococcal infections.
Turnidge J, Grayson ML
Drugs 1993 Mar;45(3):353-66. doi: 10.2165/00003495-199345030-00004. PMID: 7682906
Staphylococcal toxic shock syndrome.
Sorrell TC, Packham DR, Helprin G, Munro R, Gibson JS
Aust N Z J Obstet Gynaecol 1981 Nov;21(4):248-51. doi: 10.1111/j.1479-828x.1981.tb00143.x. PMID: 6951568

Prognosis

COVID-19 and the clinical course of rheumatic manifestations.
Ahmed S, Zimba O, Gasparyan AY
Clin Rheumatol 2021 Jul;40(7):2611-2619. Epub 2021 Mar 17 doi: 10.1007/s10067-021-05691-x. PMID: 33733315Free PMC Article
Fatal endocarditis with methicilin-sensible Staphylococcus aureus and major complications: rhabdomyolysis, pericarditis, and intracerebral hematoma: A case report and review of the literature.
Georgescu AM, Azamfirei L, Szalman K, Szekely E
Medicine (Baltimore) 2016 Oct;95(41):e5125. doi: 10.1097/MD.0000000000005125. PMID: 27741135Free PMC Article
Staphylococcal Purpura Fulminans: Report of a Case.
Honarpisheh H, Camp R, Lazova R
Am J Dermatopathol 2015 Aug;37(8):643-6. doi: 10.1097/DAD.0000000000000175. PMID: 25099358
Toxic shock syndrome.
Dass R, Nishad P, Singhi S
Indian J Pediatr 2004 May;71(5):433-5. doi: 10.1007/BF02725635. PMID: 15163875
Infectious exanthems and unusual infections.
Vincent JM, Demers DM, Bass JW
Adolesc Med 2000 Jun;11(2):327-58. PMID: 10916128

Clinical prediction guides

COVID-19 and the clinical course of rheumatic manifestations.
Ahmed S, Zimba O, Gasparyan AY
Clin Rheumatol 2021 Jul;40(7):2611-2619. Epub 2021 Mar 17 doi: 10.1007/s10067-021-05691-x. PMID: 33733315Free PMC Article
Staphylococcal toxic shock syndrome 2000-2006: epidemiology, clinical features, and molecular characteristics.
DeVries AS, Lesher L, Schlievert PM, Rogers T, Villaume LG, Danila R, Lynfield R
PLoS One 2011;6(8):e22997. Epub 2011 Aug 10 doi: 10.1371/journal.pone.0022997. PMID: 21860665Free PMC Article
Staphylococcal toxic-shock-syndrome-toxin-1 as a risk factor for disease relapse in Wegener's granulomatosis.
Popa ER, Stegeman CA, Abdulahad WH, van der Meer B, Arends J, Manson WM, Bos NA, Kallenberg CG, Tervaert JW
Rheumatology (Oxford) 2007 Jun;46(6):1029-33. Epub 2007 Apr 4 doi: 10.1093/rheumatology/kem022. PMID: 17409134
Lack of muco-cutaneous signs of toxic shock syndrome when T cells are absent: S. aureus shock in immunodeficient adults with multiple myeloma.
Kamel NS, Banks MC, Dosik A, Ursea D, Yarilina AA, Posnett DN
Clin Exp Immunol 2002 Apr;128(1):131-9. doi: 10.1046/j.1365-2249.2002.01805.x. PMID: 12033193Free PMC Article
Influence of surgery on in-vitro cytokine production by human monocytes.
Cabié A, Fitting C, Farkas JC, Laurian C, Cormier JM, Carlet J, Cavaillon JM
Cytokine 1992 Nov;4(6):576-80. doi: 10.1016/1043-4666(92)90022-j. PMID: 1292641

Recent systematic reviews

Systemic infections associated with tattoos or permanent makeup: A systematic review.
Rello J, Tejada S, Campogiani L, Adebanjo AG, Tammaro A
Med Clin (Barc) 2022 Feb 25;158(4):159-166. Epub 2021 Apr 24 doi: 10.1016/j.medcli.2021.01.014. PMID: 33902933

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