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Locally advanced breast cancer

MedGen UID:
1696434
•Concept ID:
C3495949
•
Neoplastic Process
Synonym: LABC - locally advanced breast cancer
SNOMED CT: LABC - locally advanced breast cancer (1082701000112100); Locally advanced breast cancer (1082701000112100)

Professional guidelines

PubMed

Local management after neoadjuvant treatment for breast cancer.
Sakai T, Ueno T
Chin Clin Oncol 2020 Jun;9(3):34. Epub 2020 Jun 11 doi: 10.21037/cco-20-164. PMID: 32576022
Novel radiation therapy approaches for breast cancer treatment.
Shah C, Bauer-Nilsen K, McNulty RH, Vicini F
Semin Oncol 2020 Aug;47(4):209-216. Epub 2020 May 29 doi: 10.1053/j.seminoncol.2020.05.003. PMID: 32513420
Neoadjuvant Chemoradiation in the Treatment of Locally Advanced Breast Cancer.
Chakravarthy AB
Int J Radiat Oncol Biol Phys 2017 Nov 15;99(4):784-786. doi: 10.1016/j.ijrobp.2017.08.002. PMID: 29063848

Recent clinical studies

Etiology

Impact of (18)F-Labeled Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography Versus Conventional Staging in Patients With Locally Advanced Breast Cancer.
Dayes IS, Metser U, Hodgson N, Parpia S, Eisen AF, George R, Blanchette P, Cil TD, Arnaout A, Chan A, Levine MN
J Clin Oncol 2023 Aug 10;41(23):3909-3916. Epub 2023 May 26 doi: 10.1200/JCO.23.00249. PMID: 37235845
Yoga Therapy During Chemotherapy for Early-Stage and Locally Advanced Breast Cancer.
Greaney SK, Amin N, Prudner BC, Compernolle M, Sandell LJ, Tebb SC, Weilbaecher KN, Abeln P, Luo J, Tao Y, Hirbe AC, Peterson LL
Integr Cancer Ther 2022 Jan-Dec;21:15347354221137285. doi: 10.1177/15347354221137285. PMID: 36412916Free PMC Article
Radiomics predicts the prognosis of patients with locally advanced breast cancer by reflecting the heterogeneity of tumor cells and the tumor microenvironment.
Wang X, Xie T, Luo J, Zhou Z, Yu X, Guo X
Breast Cancer Res 2022 Mar 15;24(1):20. doi: 10.1186/s13058-022-01516-0. PMID: 35292076Free PMC Article
Locally advanced breast cancer.
Aebi S, Karlsson P, Wapnir IL
Breast 2022 Mar;62 Suppl 1(Suppl 1):S58-S62. Epub 2021 Dec 15 doi: 10.1016/j.breast.2021.12.011. PMID: 34930650Free PMC Article
Ultrasound-based deep learning radiomics in the assessment of pathological complete response to neoadjuvant chemotherapy in locally advanced breast cancer.
Jiang M, Li CL, Luo XM, Chuan ZR, Lv WZ, Li X, Cui XW, Dietrich CF
Eur J Cancer 2021 Apr;147:95-105. Epub 2021 Feb 24 doi: 10.1016/j.ejca.2021.01.028. PMID: 33639324

Diagnosis

Diffuse unilateral MRI breast entities.
Sivarajah RT, Bean TR, Chetlen AL
Clin Imaging 2024 Nov;115:110305. Epub 2024 Sep 23 doi: 10.1016/j.clinimag.2024.110305. PMID: 39342818
Development and validation of a radiopathomic model for predicting pathologic complete response to neoadjuvant chemotherapy in breast cancer patients.
Zhang J, Wu Q, Yin W, Yang L, Xiao B, Wang J, Yao X
BMC Cancer 2023 May 12;23(1):431. doi: 10.1186/s12885-023-10817-2. PMID: 37173635Free PMC Article
Ultrasound-based deep learning radiomics in the assessment of pathological complete response to neoadjuvant chemotherapy in locally advanced breast cancer.
Jiang M, Li CL, Luo XM, Chuan ZR, Lv WZ, Li X, Cui XW, Dietrich CF
Eur J Cancer 2021 Apr;147:95-105. Epub 2021 Feb 24 doi: 10.1016/j.ejca.2021.01.028. PMID: 33639324
Neoadjuvant systemic therapy in breast cancer: Challenges and uncertainties.
Van de Wiel M, Dockx Y, Van den Wyngaert T, Stroobants S, Tjalma WAA, Huizing MT
Eur J Obstet Gynecol Reprod Biol 2017 Mar;210:144-156. Epub 2016 Dec 14 doi: 10.1016/j.ejogrb.2016.12.014. PMID: 28039758
Locally advanced breast cancer.
Sikov WM
Curr Treat Options Oncol 2000 Aug;1(3):228-38. doi: 10.1007/s11864-000-0034-9. PMID: 12057165

Therapy

Neoadjuvant pyrotinib, trastuzumab, and docetaxel for HER2-positive breast cancer (PHEDRA): a double-blind, randomized phase 3 trial.
Wu J, Jiang Z, Liu Z, Yang B, Yang H, Tang J, Wang K, Liu Y, Wang H, Fu P, Zhang S, Liu Q, Wang S, Huang J, Wang C, Wang S, Wang Y, Zhen L, Zhu X, Wu F, Lin X, Zou J
BMC Med 2022 Dec 27;20(1):498. doi: 10.1186/s12916-022-02708-3. PMID: 36575513Free PMC Article
Yoga Therapy During Chemotherapy for Early-Stage and Locally Advanced Breast Cancer.
Greaney SK, Amin N, Prudner BC, Compernolle M, Sandell LJ, Tebb SC, Weilbaecher KN, Abeln P, Luo J, Tao Y, Hirbe AC, Peterson LL
Integr Cancer Ther 2022 Jan-Dec;21:15347354221137285. doi: 10.1177/15347354221137285. PMID: 36412916Free PMC Article
Locally advanced breast cancer.
Aebi S, Karlsson P, Wapnir IL
Breast 2022 Mar;62 Suppl 1(Suppl 1):S58-S62. Epub 2021 Dec 15 doi: 10.1016/j.breast.2021.12.011. PMID: 34930650Free PMC Article
Ultrasound-based deep learning radiomics in the assessment of pathological complete response to neoadjuvant chemotherapy in locally advanced breast cancer.
Jiang M, Li CL, Luo XM, Chuan ZR, Lv WZ, Li X, Cui XW, Dietrich CF
Eur J Cancer 2021 Apr;147:95-105. Epub 2021 Feb 24 doi: 10.1016/j.ejca.2021.01.028. PMID: 33639324
Efficacy, Safety, and Tolerability of Pertuzumab, Trastuzumab, and Docetaxel for Patients With Early or Locally Advanced ERBB2-Positive Breast Cancer in Asia: The PEONY Phase 3 Randomized Clinical Trial.
Shao Z, Pang D, Yang H, Li W, Wang S, Cui S, Liao N, Wang Y, Wang C, Chang YC, Wang H, Kang SY, Seo JH, Shen K, Laohawiriyakamol S, Jiang Z, Li J, Zhou J, Althaus B, Mao Y, Eng-Wong J
JAMA Oncol 2020 Mar 1;6(3):e193692. Epub 2020 Mar 12 doi: 10.1001/jamaoncol.2019.3692. PMID: 31647503Free PMC Article

Prognosis

Yoga Therapy During Chemotherapy for Early-Stage and Locally Advanced Breast Cancer.
Greaney SK, Amin N, Prudner BC, Compernolle M, Sandell LJ, Tebb SC, Weilbaecher KN, Abeln P, Luo J, Tao Y, Hirbe AC, Peterson LL
Integr Cancer Ther 2022 Jan-Dec;21:15347354221137285. doi: 10.1177/15347354221137285. PMID: 36412916Free PMC Article
Radiomics predicts the prognosis of patients with locally advanced breast cancer by reflecting the heterogeneity of tumor cells and the tumor microenvironment.
Wang X, Xie T, Luo J, Zhou Z, Yu X, Guo X
Breast Cancer Res 2022 Mar 15;24(1):20. doi: 10.1186/s13058-022-01516-0. PMID: 35292076Free PMC Article
Ultrasound-based deep learning radiomics in the assessment of pathological complete response to neoadjuvant chemotherapy in locally advanced breast cancer.
Jiang M, Li CL, Luo XM, Chuan ZR, Lv WZ, Li X, Cui XW, Dietrich CF
Eur J Cancer 2021 Apr;147:95-105. Epub 2021 Feb 24 doi: 10.1016/j.ejca.2021.01.028. PMID: 33639324
Definition and consequences of locally advanced breast cancer.
Simos D, Clemons M, Ginsburg OM, Jacobs C
Curr Opin Support Palliat Care 2014 Mar;8(1):33-8. doi: 10.1097/SPC.0000000000000020. PMID: 24270749
Neoadjuvant chemotherapy with trastuzumab followed by adjuvant trastuzumab versus neoadjuvant chemotherapy alone, in patients with HER2-positive locally advanced breast cancer (the NOAH trial): a randomised controlled superiority trial with a parallel HER2-negative cohort.
Gianni L, Eiermann W, Semiglazov V, Manikhas A, Lluch A, Tjulandin S, Zambetti M, Vazquez F, Byakhow M, Lichinitser M, Climent MA, Ciruelos E, Ojeda B, Mansutti M, Bozhok A, Baronio R, Feyereislova A, Barton C, Valagussa P, Baselga J
Lancet 2010 Jan 30;375(9712):377-84. doi: 10.1016/S0140-6736(09)61964-4. PMID: 20113825

Clinical prediction guides

Locally advanced breast cancer in Eastern European developing countries.
Marian D, Fulop ZZ, Fulop RL, Molnar AH, Scurtu A, Andercou O
Ann Ital Chir 2023;94:346-350. PMID: 37794812
Yoga Therapy During Chemotherapy for Early-Stage and Locally Advanced Breast Cancer.
Greaney SK, Amin N, Prudner BC, Compernolle M, Sandell LJ, Tebb SC, Weilbaecher KN, Abeln P, Luo J, Tao Y, Hirbe AC, Peterson LL
Integr Cancer Ther 2022 Jan-Dec;21:15347354221137285. doi: 10.1177/15347354221137285. PMID: 36412916Free PMC Article
Radiomics predicts the prognosis of patients with locally advanced breast cancer by reflecting the heterogeneity of tumor cells and the tumor microenvironment.
Wang X, Xie T, Luo J, Zhou Z, Yu X, Guo X
Breast Cancer Res 2022 Mar 15;24(1):20. doi: 10.1186/s13058-022-01516-0. PMID: 35292076Free PMC Article
Ultrasound-based deep learning radiomics in the assessment of pathological complete response to neoadjuvant chemotherapy in locally advanced breast cancer.
Jiang M, Li CL, Luo XM, Chuan ZR, Lv WZ, Li X, Cui XW, Dietrich CF
Eur J Cancer 2021 Apr;147:95-105. Epub 2021 Feb 24 doi: 10.1016/j.ejca.2021.01.028. PMID: 33639324
Neo-adjuvant hormonal therapy.
Valenzuela M, Julian TB
Breast J 2008 May-Jun;14(3):279-83. Epub 2008 Mar 27 doi: 10.1111/j.1524-4741.2008.00575.x. PMID: 18373643

Recent systematic reviews

Psychological distress and coping strategies in breast cancer patients under neoadjuvant therapy: A systematic review.
Omari M, Amaadour L, El Asri A, Benbrahim Z, Mellas N, El Rhazi K, Ragala MEA, El Hilaly J, Halim K, Zarrouq B
Womens Health (Lond) 2024 Jan-Dec;20:17455057241276232. doi: 10.1177/17455057241276232. PMID: 39287572Free PMC Article
Proton therapy for locally advanced breast cancer: A systematic review of the literature.
Kammerer E, Guevelou JL, Chaikh A, Danhier S, Geffrelot J, Levy C, Saloux E, Habrand JL, Thariat J
Cancer Treat Rev 2018 Feb;63:19-27. Epub 2017 Nov 24 doi: 10.1016/j.ctrv.2017.11.006. PMID: 29197746
Primary systemic therapy and whole breast irradiation for locally advanced breast cancer: a systematic review.
Kaidar-Person O, Kuten A, Belkacemi Y; AROME
Crit Rev Oncol Hematol 2014 Nov;92(2):143-52. Epub 2014 May 2 doi: 10.1016/j.critrevonc.2014.04.005. PMID: 24881492
Breast cancer (non-metastatic).
Stebbing J, Delaney G, Thompson A
BMJ Clin Evid 2011 Feb 8;2011 PMID: 21718560Free PMC Article
Breast cancer (non-metastatic).
Stebbing J, Delaney G, Thompson A
BMJ Clin Evid 2007 Dec 4;2007 PMID: 19450345Free PMC Article

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