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Gastric choriocarcinoma

MedGen UID:
459624
•Concept ID:
C2987398
•
Neoplastic Process
Synonyms: Gastric Choriocarcinoma; gastric choriocarcinoma
 
Monarch Initiative: MONDO:0006222

Definition

A malignant germ cell tumor that arises from the stomach. It is characterized by the presence of syncytiotrophoblast and cytotrophoblast cellular components. It is often associated with lymph node and hematogenous metastases. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGastric choriocarcinoma

Professional guidelines

PubMed

Surgical management for metastatic liver tumors.
Hirai I, Kimura W, Fuse A, Isobe H, Hachiya O, Moriya T, Suto K, Mizutani M
Hepatogastroenterology 2006 Sep-Oct;53(71):757-63. PMID: 17086883
Transcatheter arterial embolization in the management of bleeding in the cancer patient.
Goldstein HM, Medellin H, Ben-Menachem Y, Wallace S
Radiology 1975 Jun;115(3):603-8. doi: 10.1148/15.3.603. PMID: 1079352

Recent clinical studies

Diagnosis

Severe thyrotoxicosis as initial presentation of gastric choriocarcinoma: a case report.
Iñiguez-Ariza NM, Cuenca D, Franco-Granillo J, Villalobos-Prieto A, Pineda-Díaz J, Baquera-Heredia J
J Med Case Rep 2022 Apr 21;16(1):159. doi: 10.1186/s13256-022-03343-5. PMID: 35443720Free PMC Article
Primary gastric choriocarcinoma.
Picazo Ferrera K, Herrera Servin MÁ, Hernández Guerrero AI
Rev Esp Enferm Dig 2020 Mar;112(3):241. doi: 10.17235/reed.2020.6478/2019. PMID: 32022576
Primary Gastric Choriocarcinoma Coexisting with Adenocarcinoma.
Lee JH, Lee JK, Kang DB
Korean J Gastroenterol 2019 Jun 25;73(6):350-354. doi: 10.4166/kjg.2019.73.6.350. PMID: 31234625
Primary gastric choriocarcinoma.
Ates O, Altundag K, Gullu I
J BUON 2018 Mar-Apr;23(2):534. PMID: 29745105
A case of primary gastric choriocarcinoma and a review of the Japanese literature.
Imai Y, Kawabe T, Takahashi M, Matsumura M, Komatsu Y, Hamada E, Niwa Y, Kurita M, Shiina S, Shimada T
J Gastroenterol 1994 Oct;29(5):642-6. doi: 10.1007/BF02365449. PMID: 8000514

Therapy

Severe thyrotoxicosis as initial presentation of gastric choriocarcinoma: a case report.
Iñiguez-Ariza NM, Cuenca D, Franco-Granillo J, Villalobos-Prieto A, Pineda-Díaz J, Baquera-Heredia J
J Med Case Rep 2022 Apr 21;16(1):159. doi: 10.1186/s13256-022-03343-5. PMID: 35443720Free PMC Article
Complete response to multidisciplinary therapy in a patient with primary gastric choriocarcinoma.
Takahashi K, Tsukamoto S, Saito K, Ohkohchi N, Hirayama K
World J Gastroenterol 2013 Aug 21;19(31):5187-94. doi: 10.3748/wjg.v19.i31.5187. PMID: 23964157Free PMC Article
Pathological complete response and two-year disease-free survival in a primary gastric choriocarcinoma patient with advanced liver metastases treated with germ cell tumor-based chemotherapy: a case report.
Waseda Y, Komai Y, Yano A, Fujii Y, Noguchi N, Kihara K
Jpn J Clin Oncol 2012 Dec;42(12):1197-201. Epub 2012 Oct 15 doi: 10.1093/jjco/hys164. PMID: 23071288
A patient with primary gastric choriocarcinoma who received a correct preoperative diagnosis and achieved prolonged survival.
Noguchi T, Takeno S, Sato T, Takahashi Y, Uchida Y, Yokoyama S
Gastric Cancer 2002;5(2):112-7. doi: 10.1007/s101200200019. PMID: 12111588
Primary gastric choriocarcinoma: a case report and review of the literature.
Liu Z, Mira JL, Cruz-Caudillo JC
Arch Pathol Lab Med 2001 Dec;125(12):1601-4. doi: 10.5858/2001-125-1601-PGC. PMID: 11735700

Prognosis

Primary Gastric Choriocarcinoma Presenting as a Pregnancy of Unknown Location.
Larish A, Kumar A, Kerr S, Langstraat C
Obstet Gynecol 2017 Feb;129(2):281-284. doi: 10.1097/AOG.0000000000001808. PMID: 28079767
Gastric choriocarcinoma admixed with an alpha-fetoprotein-producing adenocarcinoma and separated adenocarcinoma.
Eom BW, Jung SY, Yoon H, Kook MC, Ryu KW, Lee JH, Kim YW
World J Gastroenterol 2009 Oct 28;15(40):5106-8. doi: 10.3748/wjg.15.5106. PMID: 19860007Free PMC Article
Coexistent gastric primary choriocarcinoma and adenocarcinoma.
Pai MR, Mathai AM, Kumar S, Prabhu S
Indian J Pathol Microbiol 2009 Oct-Dec;52(4):537-9. doi: 10.4103/0377-4929.56155. PMID: 19805966
Primary coexistent adenocarcinoma and choriocarcinoma of the stomach. A case report and review of the literature.
Jan YJ, Chen JT, Ho WL, Wu CC, Yeh DC
J Clin Gastroenterol 1997 Oct;25(3):550-4. doi: 10.1097/00004836-199710000-00016. PMID: 9412977
A case of primary gastric choriocarcinoma and a review of the Japanese literature.
Imai Y, Kawabe T, Takahashi M, Matsumura M, Komatsu Y, Hamada E, Niwa Y, Kurita M, Shiina S, Shimada T
J Gastroenterol 1994 Oct;29(5):642-6. doi: 10.1007/BF02365449. PMID: 8000514

Clinical prediction guides

Gastric choriocarcinoma admixed with an alpha-fetoprotein-producing adenocarcinoma and separated adenocarcinoma.
Eom BW, Jung SY, Yoon H, Kook MC, Ryu KW, Lee JH, Kim YW
World J Gastroenterol 2009 Oct 28;15(40):5106-8. doi: 10.3748/wjg.15.5106. PMID: 19860007Free PMC Article
Placental alkaline phosphatase-like isoenzymes produced by human gastric cancer cells.
Aizawa K, Motoyama T, Watanabe H
Acta Pathol Jpn 1989 Oct;39(10):630-7. doi: 10.1111/j.1440-1827.1989.tb02409.x. PMID: 2686348
An autopsy case of primary gastric choriocarcinoma.
Okada K, Yokoyama S, Mochizuki Y, Moriuchi A, Yamashita H, Yasunaga A, Uchida Y, Nakayama I
Jpn J Clin Oncol 1987 Sep;17(3):263-73. PMID: 3669367
Gastric choriocarcinoma and yolk sac tumor in a man: observations about its possible origin.
Garcia RL, Ghali VS
Hum Pathol 1985 Sep;16(9):955-8. doi: 10.1016/s0046-8177(85)80137-4. PMID: 4040885
Primary gastric choriocarcinoma: immunohistochemistry, postmortem documentation, and hormonal effects in a postmenopausal female.
Wurzel J, Brooks JJ
Cancer 1981 Dec 15;48(12):2756-61. doi: 10.1002/1097-0142(19811215)48:12<2756::aid-cncr2820481233>3.0.co;2-6. PMID: 6171335

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