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Locally Recurrent Malignant Neoplasm

MedGen UID:
458908
•Concept ID:
C2986682
•
Neoplastic Process
Synonyms: Locally Recurrent Cancer; Locoregional Recurrence

Definition

The reemergence of a malignant neoplasm after a period of remission at the site of the original tumor or adjacent to it. [from NCI]

Professional guidelines

PubMed

European consensus-based interdisciplinary guideline for diagnosis and treatment of basal cell carcinoma-update 2023.
Peris K, Fargnoli MC, Kaufmann R, Arenberger P, Bastholt L, Seguin NB, Bataille V, Brochez L, Del Marmol V, Dummer R, Forsea AM, Gaudy-Marqueste C, Harwood CA, Hauschild A, Höller C, Kandolf L, Kellerners-Smeets NWJ, Lallas A, Leiter U, Malvehy J, Marinović B, Mijuskovic Z, Moreno-Ramirez D, Nagore E, Nathan P, Stratigos AJ, Stockfleth E, Tagliaferri L, Trakatelli M, Vieira R, Zalaudek I, Garbe C; EADO”A, EDF”B, ESTRO”C, UEMS”D and EADV”E
Eur J Cancer 2023 Oct;192:113254. Epub 2023 Jul 28 doi: 10.1016/j.ejca.2023.113254. PMID: 37604067
Expert consensus document: Clinical and molecular diagnosis, screening and management of Beckwith-Wiedemann syndrome: an international consensus statement.
Brioude F, Kalish JM, Mussa A, Foster AC, Bliek J, Ferrero GB, Boonen SE, Cole T, Baker R, Bertoletti M, Cocchi G, Coze C, De Pellegrin M, Hussain K, Ibrahim A, Kilby MD, Krajewska-Walasek M, Kratz CP, Ladusans EJ, Lapunzina P, Le Bouc Y, Maas SM, Macdonald F, Õunap K, Peruzzi L, Rossignol S, Russo S, Shipster C, Skórka A, Tatton-Brown K, Tenorio J, Tortora C, Grønskov K, Netchine I, Hennekam RC, Prawitt D, Tümer Z, Eggermann T, Mackay DJG, Riccio A, Maher ER
Nat Rev Endocrinol 2018 Apr;14(4):229-249. Epub 2018 Jan 29 doi: 10.1038/nrendo.2017.166. PMID: 29377879Free PMC Article
Clinical Diagnosis and Management of Breast Cancer.
McDonald ES, Clark AS, Tchou J, Zhang P, Freedman GM
J Nucl Med 2016 Feb;57 Suppl 1:9S-16S. doi: 10.2967/jnumed.115.157834. PMID: 26834110

Recent clinical studies

Etiology

Immune Checkpoint Inhibitors in Patients with Pre-existing Neurologic Autoimmune Disorders.
Aoun R, Gratch D, Kaminetzky D, Kister I
Curr Neurol Neurosci Rep 2023 Nov;23(11):735-750. Epub 2023 Oct 23 doi: 10.1007/s11910-023-01306-x. PMID: 37870664
Spatially restricted tumour-associated and host-associated immune drivers correlate with the recurrence sites of pancreatic cancer.
Karamitopoulou E, Wenning AS, Acharjee A, Zlobec I, Aeschbacher P, Perren A, Gloor B
Gut 2023 Aug;72(8):1523-1533. Epub 2023 Feb 15 doi: 10.1136/gutjnl-2022-329371. PMID: 36792355
Management of locally recurrent nasopharyngeal carcinoma.
Lee AWM, Ng WT, Chan JYW, Corry J, Mäkitie A, Mendenhall WM, Rinaldo A, Rodrigo JP, Saba NF, Strojan P, Suárez C, Vermorken JB, Yom SS, Ferlito A
Cancer Treat Rev 2019 Sep;79:101890. Epub 2019 Aug 21 doi: 10.1016/j.ctrv.2019.101890. PMID: 31470314
Early Detection of Metastatic Relapse and Monitoring of Therapeutic Efficacy by Ultra-Deep Sequencing of Plasma Cell-Free DNA in Patients With Urothelial Bladder Carcinoma.
Christensen E, Birkenkamp-Demtröder K, Sethi H, Shchegrova S, Salari R, Nordentoft I, Wu HT, Knudsen M, Lamy P, Lindskrog SV, Taber A, Balcioglu M, Vang S, Assaf Z, Sharma S, Tin AS, Srinivasan R, Hafez D, Reinert T, Navarro S, Olson A, Ram R, Dashner S, Rabinowitz M, Billings P, Sigurjonsson S, Andersen CL, Swenerton R, Aleshin A, Zimmermann B, Agerbæk M, Lin CJ, Jensen JB, Dyrskjøt L
J Clin Oncol 2019 Jun 20;37(18):1547-1557. Epub 2019 May 6 doi: 10.1200/JCO.18.02052. PMID: 31059311
Esthesioneuroblastoma.
Elkon D, Hightower SI, Lim ML, Cantrell RW, Constable WC
Cancer 1979 Sep;44(3):1087-94. doi: 10.1002/1097-0142(197909)44:3<1087::aid-cncr2820440343>3.0.co;2-a. PMID: 383268

Diagnosis

PSMA PET for Detection of Recurrence.
Duan H, Iagaru A
Semin Nucl Med 2024 Jan;54(1):77-86. Epub 2023 Aug 9 doi: 10.1053/j.semnuclmed.2023.07.002. PMID: 37567795
Central Nervous System Lymphoma.
Schaff L
Continuum (Minneap Minn) 2023 Dec 1;29(6):1710-1726. doi: 10.1212/CON.0000000000001356. PMID: 38085895
Management of locally recurrent nasopharyngeal carcinoma.
Lee AWM, Ng WT, Chan JYW, Corry J, Mäkitie A, Mendenhall WM, Rinaldo A, Rodrigo JP, Saba NF, Strojan P, Suárez C, Vermorken JB, Yom SS, Ferlito A
Cancer Treat Rev 2019 Sep;79:101890. Epub 2019 Aug 21 doi: 10.1016/j.ctrv.2019.101890. PMID: 31470314
Early Detection of Metastatic Relapse and Monitoring of Therapeutic Efficacy by Ultra-Deep Sequencing of Plasma Cell-Free DNA in Patients With Urothelial Bladder Carcinoma.
Christensen E, Birkenkamp-Demtröder K, Sethi H, Shchegrova S, Salari R, Nordentoft I, Wu HT, Knudsen M, Lamy P, Lindskrog SV, Taber A, Balcioglu M, Vang S, Assaf Z, Sharma S, Tin AS, Srinivasan R, Hafez D, Reinert T, Navarro S, Olson A, Ram R, Dashner S, Rabinowitz M, Billings P, Sigurjonsson S, Andersen CL, Swenerton R, Aleshin A, Zimmermann B, Agerbæk M, Lin CJ, Jensen JB, Dyrskjøt L
J Clin Oncol 2019 Jun 20;37(18):1547-1557. Epub 2019 May 6 doi: 10.1200/JCO.18.02052. PMID: 31059311
Esthesioneuroblastoma.
Elkon D, Hightower SI, Lim ML, Cantrell RW, Constable WC
Cancer 1979 Sep;44(3):1087-94. doi: 10.1002/1097-0142(197909)44:3<1087::aid-cncr2820440343>3.0.co;2-a. PMID: 383268

Therapy

Immune-checkpoint inhibitors for glioblastoma: what have we learned?
Omuro A
Arq Neuropsiquiatr 2022 May;80(5 Suppl 1):266-269. doi: 10.1590/0004-282X-ANP-2022-S129. PMID: 35976319Free PMC Article
Phase 3, randomized, open-label study of pembrolizumab plus lenvatinib versus chemotherapy for first-line treatment of advanced or recurrent endometrial cancer: ENGOT-en9/LEAP-001.
Marth C, Tarnawski R, Tyulyandina A, Pignata S, Gilbert L, Kaen D, Rubio MJ, Frentzas S, Beiner M, Magallanes-Maciel M, Farrelly L, Choi CH, Berger R, Lee C, Vulsteke C, Hasegawa K, Braicu EI, Wu X, McKenzie J, Lee JJ, Makker V
Int J Gynecol Cancer 2022 Jan;32(1):93-100. Epub 2021 Nov 19 doi: 10.1136/ijgc-2021-003017. PMID: 34799418Free PMC Article
How did lomustine become standard of care in recurrent glioblastoma?
Weller M, Le Rhun E
Cancer Treat Rev 2020 Jul;87:102029. Epub 2020 May 4 doi: 10.1016/j.ctrv.2020.102029. PMID: 32408220
Post-prostatectomy radiation therapy for locally recurrent prostate cancer.
Isharwal S, Stephenson AJ
Expert Rev Anticancer Ther 2017 Nov;17(11):1003-1012. Epub 2017 Sep 18 doi: 10.1080/14737140.2017.1378575. PMID: 28922958
Malignant pericardial effusion.
Burazor I, Imazio M, Markel G, Adler Y
Cardiology 2013;124(4):224-32. Epub 2013 Apr 5 doi: 10.1159/000348559. PMID: 23571453

Prognosis

Atypical meningioma: patterns of postradiotherapy recurrences.
Schuring-Pereira M, Hagenbeek R, Mast M, Nandoe Tewarie R, van Santvoort JPC, van Duinen S, Wiggenraad R
Br J Neurosurg 2021 Oct;35(5):591-596. Epub 2021 Jun 1 doi: 10.1080/02688697.2021.1922606. PMID: 34074192
Prognosis of Primary and Recurrent Chondrosarcoma of the Rib.
Roos E, van Coevorden F, Verhoef C, Wouters MW, Kroon HM, Hogendoorn PC, van Houdt WJ
Ann Surg Oncol 2016 Mar;23(3):811-7. Epub 2015 Oct 23 doi: 10.1245/s10434-015-4932-2. PMID: 26498768
Follow-up: the evidence.
D'Ugo D, Biondi A, Tufo A, Persiani R
Dig Surg 2013;30(2):159-68. Epub 2013 Jul 18 doi: 10.1159/000350878. PMID: 23867593
Recurrent well-differentiated thyroid carcinoma.
Magarey MJ, Freeman JL
Oral Oncol 2013 Jul;49(7):689-94. Epub 2013 Apr 25 doi: 10.1016/j.oraloncology.2013.03.434. PMID: 23623403
Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer.
Veronesi U, Cascinelli N, Mariani L, Greco M, Saccozzi R, Luini A, Aguilar M, Marubini E
N Engl J Med 2002 Oct 17;347(16):1227-32. doi: 10.1056/NEJMoa020989. PMID: 12393819

Clinical prediction guides

Spatially Resolved Tumor Microenvironment Predicts Treatment Outcomes in Relapsed/Refractory Hodgkin Lymphoma.
Aoki T, Jiang A, Xu A, Yin Y, Gamboa A, Milne K, Takata K, Miyata-Takata T, Chung S, Rai S, Wu S, Warren M, Strong C, Goodyear T, Morris K, Chong LC, Hav M, Colombo AR, Telenius A, Boyle M, Ben-Neriah S, Power M, Gerrie AS, Weng AP, Karsan A, Roth A, Farinha P, Scott DW, Savage KJ, Nelson BH, Merchant A, Steidl C
J Clin Oncol 2024 Mar 20;42(9):1077-1087. Epub 2023 Dec 19 doi: 10.1200/JCO.23.01115. PMID: 38113419Free PMC Article
Low-Grade Uterine Leiomyosarcoma Is Highly Sensitive to Hormonal Treatment.
Sanfilippo R, Sbaraglia M, Fabbroni C, Croce S, Ray-Coquard I, Guermazi F, Paolini B, Blanc-Durand F, Lecesne A, Chiappa V, Dei Tos AP, Casali PG
Clin Cancer Res 2023 Nov 14;29(22):4679-4684. doi: 10.1158/1078-0432.CCR-23-0692. PMID: 37699075
Assessment of 68Ga-PSMA-11 PET Accuracy in Localizing Recurrent Prostate Cancer: A Prospective Single-Arm Clinical Trial.
Fendler WP, Calais J, Eiber M, Flavell RR, Mishoe A, Feng FY, Nguyen HG, Reiter RE, Rettig MB, Okamoto S, Emmett L, Zacho HD, Ilhan H, Wetter A, Rischpler C, Schoder H, Burger IA, Gartmann J, Smith R, Small EJ, Slavik R, Carroll PR, Herrmann K, Czernin J, Hope TA
JAMA Oncol 2019 Jun 1;5(6):856-863. doi: 10.1001/jamaoncol.2019.0096. PMID: 30920593Free PMC Article
Recurrent well-differentiated thyroid carcinoma.
Magarey MJ, Freeman JL
Oral Oncol 2013 Jul;49(7):689-94. Epub 2013 Apr 25 doi: 10.1016/j.oraloncology.2013.03.434. PMID: 23623403
Nephrogenic adenoma.
Amin W, Parwani AV
Pathol Res Pract 2010 Oct 15;206(10):659-62. Epub 2010 Jul 8 doi: 10.1016/j.prp.2010.06.001. PMID: 20619548

Recent systematic reviews

Management of phyllodes tumor: A systematic review and meta-analysis of real-world evidence.
Yu CY, Huang TW, Tam KW
Int J Surg 2022 Nov;107:106969. Epub 2022 Oct 31 doi: 10.1016/j.ijsu.2022.106969. PMID: 36328344
Malignant phyllodes tumor of the breast: a systematic review.
Lissidini G, Mulè A, Santoro A, Papa G, Nicosia L, Cassano E, Ashoor AA, Veronesi P, Pantanowitz L, Hornick JL, Rossi ED
Pathologica 2022 Apr;114(2):111-120. Epub 2022 Apr 13 doi: 10.32074/1591-951X-754. PMID: 35414723Free PMC Article
Radical vs conservative treatment of intraosseous ameloblastoma: Systematic review and meta-analysis.
Hendra FN, Natsir Kalla DS, Van Cann EM, de Vet HCW, Helder MN, Forouzanfar T
Oral Dis 2019 Oct;25(7):1683-1696. Epub 2019 Jan 1 doi: 10.1111/odi.13014. PMID: 30548549
Neuroendocrine carcinoma of the cervix: a systematic review of the literature.
Tempfer CB, Tischoff I, Dogan A, Hilal Z, Schultheis B, Kern P, Rezniczek GA
BMC Cancer 2018 May 4;18(1):530. doi: 10.1186/s12885-018-4447-x. PMID: 29728073Free PMC Article
The management of menopause in women with a history of endometriosis: a systematic review.
Gemmell LC, Webster KE, Kirtley S, Vincent K, Zondervan KT, Becker CM
Hum Reprod Update 2017 Jul 1;23(4):481-500. doi: 10.1093/humupd/dmx011. PMID: 28498913Free PMC Article

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