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Obesity, Visceral

MedGen UID:
423468
•Concept ID:
C2936179
•
Sign or Symptom
Synonyms: Obesities, Visceral; Visceral Obesities; Visceral Obesity

Definition

Obesity due to excessive deposition of INTRA-ABDOMINAL FAT in the abdominal VISCERA and OMENTUM. [from MeSH]

Professional guidelines

PubMed

Assessment of causal effects of visceral adipose tissue on risk of cancers: a Mendelian randomization study.
Lu Y, Tang H, Huang P, Wang J, Deng P, Li Y, Zheng J, Weng L
Int J Epidemiol 2022 Aug 10;51(4):1204-1218. doi: 10.1093/ije/dyac025. PMID: 35218345Free PMC Article
Waist circumference as a vital sign in clinical practice: a Consensus Statement from the IAS and ICCR Working Group on Visceral Obesity.
Ross R, Neeland IJ, Yamashita S, Shai I, Seidell J, Magni P, Santos RD, Arsenault B, Cuevas A, Hu FB, Griffin BA, Zambon A, Barter P, Fruchart JC, Eckel RH, Matsuzawa Y, Després JP
Nat Rev Endocrinol 2020 Mar;16(3):177-189. Epub 2020 Feb 4 doi: 10.1038/s41574-019-0310-7. PMID: 32020062Free PMC Article
Visceral and ectopic fat, atherosclerosis, and cardiometabolic disease: a position statement.
Neeland IJ, Ross R, Després JP, Matsuzawa Y, Yamashita S, Shai I, Seidell J, Magni P, Santos RD, Arsenault B, Cuevas A, Hu FB, Griffin B, Zambon A, Barter P, Fruchart JC, Eckel RH; International Atherosclerosis Society; International Chair on Cardiometabolic Risk Working Group on Visceral Obesity
Lancet Diabetes Endocrinol 2019 Sep;7(9):715-725. Epub 2019 Jul 10 doi: 10.1016/S2213-8587(19)30084-1. PMID: 31301983

Recent clinical studies

Etiology

AI-based CT Body Composition Identifies Myosteatosis as Key Mortality Predictor in Asymptomatic Adults.
Nachit M, Horsmans Y, Summers RM, Leclercq IA, Pickhardt PJ
Radiology 2023 Jun;307(5):e222008. Epub 2023 May 16 doi: 10.1148/radiol.222008. PMID: 37191484Free PMC Article
Computed Tomography-Derived Myosteatosis and Metabolic Disorders.
Miljkovic I, Vella CA, Allison M
Diabetes Metab J 2021 Jul;45(4):482-491. Epub 2021 Jul 30 doi: 10.4093/dmj.2020.0277. PMID: 34352985Free PMC Article
Metabolic Syndrome in Hypopituitarism.
Miljić D, Popovic V
Front Horm Res 2018;49:1-19. Epub 2018 Apr 5 doi: 10.1159/000485997. PMID: 29895033
Cardiovascular risk of adipokines: a review.
Dutheil F, Gordon BA, Naughton G, Crendal E, Courteix D, Chaplais E, Thivel D, Lac G, Benson AC
J Int Med Res 2018 Jun;46(6):2082-2095. Epub 2017 Sep 25 doi: 10.1177/0300060517706578. PMID: 28974138Free PMC Article
ASH and NASH.
Scaglioni F, Ciccia S, Marino M, Bedogni G, Bellentani S
Dig Dis 2011;29(2):202-10. Epub 2011 Jul 5 doi: 10.1159/000323886. PMID: 21734385

Diagnosis

Effects of additive interactions among obesity, visceral adiposity, and sarcopenia on nonalcoholic fatty liver disease.
Chung GE, Oh S, Ahn DW, Kim SH, Jung YJ, Kim JW, Kim BG, Lee KL, Jeong JB
Sci Rep 2023 Mar 3;13(1):3628. doi: 10.1038/s41598-023-30833-3. PMID: 36869158Free PMC Article
Obesity, visceral adiposity and carotid atherosclerosis.
Haberka M, Skilton M, Biedroń M, Szóstak-Janiak K, Partyka M, Matla M, Gąsior Z
J Diabetes Complications 2019 Apr;33(4):302-306. Epub 2019 Jan 17 doi: 10.1016/j.jdiacomp.2019.01.002. PMID: 30770289
Cardiovascular risk of adipokines: a review.
Dutheil F, Gordon BA, Naughton G, Crendal E, Courteix D, Chaplais E, Thivel D, Lac G, Benson AC
J Int Med Res 2018 Jun;46(6):2082-2095. Epub 2017 Sep 25 doi: 10.1177/0300060517706578. PMID: 28974138Free PMC Article
MicroRNAs as controlled systems and controllers in non-alcoholic fatty liver disease.
Panera N, Gnani D, Crudele A, Ceccarelli S, Nobili V, Alisi A
World J Gastroenterol 2014 Nov 7;20(41):15079-86. doi: 10.3748/wjg.v20.i41.15079. PMID: 25386056Free PMC Article
ASH and NASH.
Scaglioni F, Ciccia S, Marino M, Bedogni G, Bellentani S
Dig Dis 2011;29(2):202-10. Epub 2011 Jul 5 doi: 10.1159/000323886. PMID: 21734385

Therapy

Adipose tissue macrophage-derived microRNA-210-3p disrupts systemic insulin sensitivity by silencing GLUT4 in obesity.
Patra D, Ramprasad P, Sharma S, Dey U, Kumar V, Singh S, Dasgupta S, Kumar A, Tikoo K, Pal D
J Biol Chem 2024 Jun;300(6):107328. Epub 2024 Apr 26 doi: 10.1016/j.jbc.2024.107328. PMID: 38679332Free PMC Article
Metabolic Syndrome in Hypopituitarism.
Miljić D, Popovic V
Front Horm Res 2018;49:1-19. Epub 2018 Apr 5 doi: 10.1159/000485997. PMID: 29895033
Visceral Adiposity and Sarcopenic Visceral Obesity are Associated with Poor Prognosis After Resection of Pancreatic Cancer.
Okumura S, Kaido T, Hamaguchi Y, Kobayashi A, Shirai H, Yao S, Yagi S, Kamo N, Hatano E, Okajima H, Takaori K, Uemoto S
Ann Surg Oncol 2017 Nov;24(12):3732-3740. Epub 2017 Sep 5 doi: 10.1245/s10434-017-6077-y. PMID: 28871520
Obesity, Visceral Adipose Tissue, and Cognitive Function in Childhood.
Raine LB, Khan NA, Drollette ES, Pontifex MB, Kramer AF, Hillman CH
J Pediatr 2017 Aug;187:134-140.e3. Epub 2017 Jun 13 doi: 10.1016/j.jpeds.2017.05.023. PMID: 28622956Free PMC Article
The future of obesity reduction: beyond weight loss.
Ross R, Bradshaw AJ
Nat Rev Endocrinol 2009 Jun;5(6):319-25. doi: 10.1038/nrendo.2009.78. PMID: 19421242

Prognosis

Obesity/cardiometabolic phenotype of heart failure with preserved ejection fraction: mechanisms to recent trials.
Verma R, Dhingra NK, Connelly KA
Curr Opin Cardiol 2024 Mar 1;39(2):92-97. Epub 2024 Jan 25 doi: 10.1097/HCO.0000000000001113. PMID: 38294186
AI-based CT Body Composition Identifies Myosteatosis as Key Mortality Predictor in Asymptomatic Adults.
Nachit M, Horsmans Y, Summers RM, Leclercq IA, Pickhardt PJ
Radiology 2023 Jun;307(5):e222008. Epub 2023 May 16 doi: 10.1148/radiol.222008. PMID: 37191484Free PMC Article
Computed Tomography-Derived Myosteatosis and Metabolic Disorders.
Miljkovic I, Vella CA, Allison M
Diabetes Metab J 2021 Jul;45(4):482-491. Epub 2021 Jul 30 doi: 10.4093/dmj.2020.0277. PMID: 34352985Free PMC Article
Obesity, visceral adiposity and carotid atherosclerosis.
Haberka M, Skilton M, Biedroń M, Szóstak-Janiak K, Partyka M, Matla M, Gąsior Z
J Diabetes Complications 2019 Apr;33(4):302-306. Epub 2019 Jan 17 doi: 10.1016/j.jdiacomp.2019.01.002. PMID: 30770289
The obesity paradox: is it really a paradox? Hypertension.
Lechi A
Eat Weight Disord 2017 Mar;22(1):43-48. Epub 2016 Nov 4 doi: 10.1007/s40519-016-0330-4. PMID: 27812911

Clinical prediction guides

AI-based CT Body Composition Identifies Myosteatosis as Key Mortality Predictor in Asymptomatic Adults.
Nachit M, Horsmans Y, Summers RM, Leclercq IA, Pickhardt PJ
Radiology 2023 Jun;307(5):e222008. Epub 2023 May 16 doi: 10.1148/radiol.222008. PMID: 37191484Free PMC Article
Association of obesity, visceral adiposity, and sarcopenia with an increased risk of metabolic syndrome: A retrospective study.
Kim SH, Kang HW, Jeong JB, Lee DS, Ahn DW, Kim JW, Kim BG, Lee KL, Oh S, Yoon SH, Park SJ
PLoS One 2021;16(8):e0256083. Epub 2021 Aug 17 doi: 10.1371/journal.pone.0256083. PMID: 34403431Free PMC Article
Computed Tomography-Derived Myosteatosis and Metabolic Disorders.
Miljkovic I, Vella CA, Allison M
Diabetes Metab J 2021 Jul;45(4):482-491. Epub 2021 Jul 30 doi: 10.4093/dmj.2020.0277. PMID: 34352985Free PMC Article
Obesity, visceral adiposity and carotid atherosclerosis.
Haberka M, Skilton M, Biedroń M, Szóstak-Janiak K, Partyka M, Matla M, Gąsior Z
J Diabetes Complications 2019 Apr;33(4):302-306. Epub 2019 Jan 17 doi: 10.1016/j.jdiacomp.2019.01.002. PMID: 30770289
The obesity paradox: is it really a paradox? Hypertension.
Lechi A
Eat Weight Disord 2017 Mar;22(1):43-48. Epub 2016 Nov 4 doi: 10.1007/s40519-016-0330-4. PMID: 27812911

Supplemental Content

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