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Auditory neuropathy spectrum disorder

MedGen UID:
751969
Concept ID:
C2732267
Disease or Syndrome
Synonyms: Auditory Neuropathy; Auditory Neuropathy Spectrum Disorder; Auditory neuropathy with dys-synchrony
SNOMED CT: Auditory neuropathy spectrum disorder (443805006); Auditory neuropathy with dys-synchrony (443805006)

Definition

A hearing disorder characterized by impaired transmission of signals through the auditory nerve, resulting in mild to severe hearing loss and poor speech perception. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Auditory neuropathy spectrum disorder

Professional guidelines

PubMed

Acke FRE, De Vriese C, Van Hoecke H, De Leenheer EMR
Eur Arch Otorhinolaryngol 2022 Jul;279(7):3371-3378. Epub 2021 Aug 31 doi: 10.1007/s00405-021-07060-5. PMID: 34463816
Ezzeldin ZM, Sharaf E, Hamdy HS, Abdelwahab Selim YA
Int J Pediatr Otorhinolaryngol 2021 Mar;142:110591. Epub 2020 Dec 23 doi: 10.1016/j.ijporl.2020.110591. PMID: 33360868
Pham NS
Curr Opin Otolaryngol Head Neck Surg 2017 Oct;25(5):396-399. doi: 10.1097/MOO.0000000000000390. PMID: 28708635

Recent clinical studies

Etiology

Almishaal AA, Saleh S, Alferaih H, Alhelo O
Int J Audiol 2022 Dec;61(12):1018-1026. Epub 2021 Dec 20 doi: 10.1080/14992027.2021.2014074. PMID: 34928752
Mahomva C, Liu YC, Raol N, Anne S
Otolaryngol Head Neck Surg 2022 May;166(5):964-969. Epub 2021 Jul 27 doi: 10.1177/01945998211029836. PMID: 34311620
Myers K, Nicholson N
Am J Audiol 2021 Sep 10;30(3):777-789. Epub 2021 Jul 23 doi: 10.1044/2021_AJA-20-00175. PMID: 34297601
James AL, Chakraborty P, Tomlinson C, Harrison RV
Int J Pediatr Otorhinolaryngol 2020 Oct;137:110238. Epub 2020 Jul 2 doi: 10.1016/j.ijporl.2020.110238. PMID: 32896351
Harrison RV, Gordon KA, Papsin BC, Negandhi J, James AL
Int J Pediatr Otorhinolaryngol 2015 Dec;79(12):1980-7. Epub 2015 Oct 17 doi: 10.1016/j.ijporl.2015.10.006. PMID: 26545793

Diagnosis

Mahomva C, Liu YC, Raol N, Anne S
Otolaryngol Head Neck Surg 2022 May;166(5):964-969. Epub 2021 Jul 27 doi: 10.1177/01945998211029836. PMID: 34311620
Yawn RJ, Nassiri AM, Rivas A
Otolaryngol Clin North Am 2019 Apr;52(2):349-355. Epub 2019 Feb 12 doi: 10.1016/j.otc.2018.11.016. PMID: 30765091
Harrison RV, Gordon KA, Papsin BC, Negandhi J, James AL
Int J Pediatr Otorhinolaryngol 2015 Dec;79(12):1980-7. Epub 2015 Oct 17 doi: 10.1016/j.ijporl.2015.10.006. PMID: 26545793
Sharma A, Cardon G
Hear Res 2015 Dec;330(Pt B):221-32. Epub 2015 Jun 10 doi: 10.1016/j.heares.2015.06.001. PMID: 26070426Free PMC Article
Norrix LW, Velenovsky DS
J Speech Lang Hear Res 2014 Aug;57(4):1564-76. doi: 10.1044/2014_JSLHR-H-13-0213. PMID: 24686491

Therapy

Mahomva C, Liu YC, Raol N, Anne S
Otolaryngol Head Neck Surg 2022 May;166(5):964-969. Epub 2021 Jul 27 doi: 10.1177/01945998211029836. PMID: 34311620
West AN, Kuan EC, Peng KA
Laryngoscope 2021 Mar;131(3):671-674. Epub 2020 Jul 1 doi: 10.1002/lary.28904. PMID: 32609896
Brough H
Trop Doct 2020 Jul;50(3):246-248. Epub 2020 Apr 14 doi: 10.1177/0049475520917236. PMID: 32290759
Wasson JD, Briggs RJ
Int J Audiol 2016;55 Suppl 2:S77-87. Epub 2016 Jun 7 doi: 10.1080/14992027.2016.1184765. PMID: 27266370
Sharma A, Cardon G
Hear Res 2015 Dec;330(Pt B):221-32. Epub 2015 Jun 10 doi: 10.1016/j.heares.2015.06.001. PMID: 26070426Free PMC Article

Prognosis

Chen K, Liu M, Wu X, Zong L, Jiang H
Int J Pediatr Otorhinolaryngol 2018 Dec;115:19-23. Epub 2018 Sep 14 doi: 10.1016/j.ijporl.2018.09.008. PMID: 30368385
Harrison RV, Gordon KA, Papsin BC, Negandhi J, James AL
Int J Pediatr Otorhinolaryngol 2015 Dec;79(12):1980-7. Epub 2015 Oct 17 doi: 10.1016/j.ijporl.2015.10.006. PMID: 26545793
Sharma A, Cardon G
Hear Res 2015 Dec;330(Pt B):221-32. Epub 2015 Jun 10 doi: 10.1016/j.heares.2015.06.001. PMID: 26070426Free PMC Article
Norrix LW, Velenovsky DS
J Speech Lang Hear Res 2014 Aug;57(4):1564-76. doi: 10.1044/2014_JSLHR-H-13-0213. PMID: 24686491
Zhang QJ, Lan L, Shi W, Wang DY, Qi Y, Zong L, Li Q, Wang H, Ding HN, Li N, Han B, Wang QJ
Acta Otolaryngol 2012 Jan;132(1):72-9. Epub 2011 Nov 10 doi: 10.3109/00016489.2011.629630. PMID: 22073929

Clinical prediction guides

Myers K, Nicholson N
Am J Audiol 2021 Sep 10;30(3):777-789. Epub 2021 Jul 23 doi: 10.1044/2021_AJA-20-00175. PMID: 34297601
West AN, Kuan EC, Peng KA
Laryngoscope 2021 Mar;131(3):671-674. Epub 2020 Jul 1 doi: 10.1002/lary.28904. PMID: 32609896
Fontenot TE, Giardina CK, Teagle HF, Park LR, Adunka OF, Buchman CA, Brown KD, Fitzpatrick DC
Int J Pediatr Otorhinolaryngol 2017 Aug;99:120-127. Epub 2017 Jun 5 doi: 10.1016/j.ijporl.2017.05.026. PMID: 28688553Free PMC Article
Sharma A, Cardon G
Hear Res 2015 Dec;330(Pt B):221-32. Epub 2015 Jun 10 doi: 10.1016/j.heares.2015.06.001. PMID: 26070426Free PMC Article
Norrix LW, Velenovsky DS
J Speech Lang Hear Res 2014 Aug;57(4):1564-76. doi: 10.1044/2014_JSLHR-H-13-0213. PMID: 24686491

Recent systematic reviews

Sahwan M, Abdelsamad Y, Alasfoor F, Alfayez F, Binkhamis G, Nichani J
Eur Arch Otorhinolaryngol 2024 Mar;281(3):1149-1162. Epub 2023 Aug 28 doi: 10.1007/s00405-023-08194-4. PMID: 37638998
Burdo S, Di Berardino F, Bruno G
Acta Otorhinolaryngol Ital 2021 Dec;41(6):496-506. Epub 2021 Nov 26 doi: 10.14639/0392-100X-N0932. PMID: 34825666Free PMC Article
Myers K, Nicholson N
Am J Audiol 2021 Sep 10;30(3):777-789. Epub 2021 Jul 23 doi: 10.1044/2021_AJA-20-00175. PMID: 34297601
Harrison RV, Gordon KA, Papsin BC, Negandhi J, James AL
Int J Pediatr Otorhinolaryngol 2015 Dec;79(12):1980-7. Epub 2015 Oct 17 doi: 10.1016/j.ijporl.2015.10.006. PMID: 26545793
Roush P, Frymark T, Venediktov R, Wang B
Am J Audiol 2011 Dec;20(2):159-70. Epub 2011 Sep 22 doi: 10.1044/1059-0889(2011/10-0032). PMID: 21940978

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