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Hypothalamic-pituitary-adrenal axis dysfunction

MedGen UID:
750802
•Concept ID:
C2711029
•
Disease or Syndrome
SNOMED CT: Hypothalamic-pituitary-adrenal axis dysfunction (442762009)

Professional guidelines

PubMed

Cortisol and Subjective Stress Responses to Acute Psychosocial Stress in Fibromyalgia Patients and Control Participants.
Coppens E, Kempke S, Van Wambeke P, Claes S, Morlion B, Luyten P, Van Oudenhove L
Psychosom Med 2018 Apr;80(3):317-326. doi: 10.1097/PSY.0000000000000551. PMID: 29232329
Impact of depression and its treatment on the bones of growing children.
Weller EB, Weller RA, Kloos AL, Hitchcock S, Kim WJ, Zemel B
Curr Psychiatry Rep 2007 Apr;9(2):94-8. doi: 10.1007/s11920-007-0077-8. PMID: 17389117

Recent clinical studies

Etiology

Adrenal insufficiency in patients with Prader-Willi syndrome.
Kusz MJ, Gawlik AM
Front Endocrinol (Lausanne) 2022;13:1021704. Epub 2022 Nov 17 doi: 10.3389/fendo.2022.1021704. PMID: 36465638Free PMC Article
Hypothalamic-pituitary-adrenal axis suppression and intranasal corticosteroid use: A systematic review and meta-analysis.
Sampieri G, Namavarian A, Lee JJW, Hamour AF, Lee JM
Int Forum Allergy Rhinol 2022 Jan;12(1):11-27. Epub 2021 Jul 14 doi: 10.1002/alr.22863. PMID: 34260153
Hypothalamic-Pituitary-Adrenal axis dysfunction by early life stress.
Juruena MF, Bourne M, Young AH, Cleare AJ
Neurosci Lett 2021 Aug 10;759:136037. Epub 2021 Jun 8 doi: 10.1016/j.neulet.2021.136037. PMID: 34116195
DHEA, DHEAS and PCOS.
Goodarzi MO, Carmina E, Azziz R
J Steroid Biochem Mol Biol 2015 Jan;145:213-25. Epub 2014 Jul 5 doi: 10.1016/j.jsbmb.2014.06.003. PMID: 25008465
Hypothalamic-pituitary-adrenal axis dysfunction as a neurobiological correlate of emotion dysregulation in adolescent suicide.
Braquehais MD, Picouto MD, Casas M, Sher L
World J Pediatr 2012 Aug;8(3):197-206. Epub 2012 Aug 12 doi: 10.1007/s12519-012-0358-0. PMID: 22886191

Diagnosis

Identification of biopsychological trait markers in functional neurological disorders.
Weber S, Bühler J, Vanini G, Loukas S, Bruckmaier R, Aybek S
Brain 2023 Jun 1;146(6):2627-2641. doi: 10.1093/brain/awac442. PMID: 36417451Free PMC Article
Adrenal insufficiency in patients with Prader-Willi syndrome.
Kusz MJ, Gawlik AM
Front Endocrinol (Lausanne) 2022;13:1021704. Epub 2022 Nov 17 doi: 10.3389/fendo.2022.1021704. PMID: 36465638Free PMC Article
Psychological sequelae of myocardial infarction.
Kumar M, Nayak PK
Biomed Pharmacother 2017 Nov;95:487-496. Epub 2017 Sep 12 doi: 10.1016/j.biopha.2017.08.109. PMID: 28866415
Hypothalamic-pituitary-adrenal axis suppression in asthmatic school children.
Zöllner EW, Lombard CJ, Galal U, Hough FS, Irusen EM, Weinberg E
Pediatrics 2012 Dec;130(6):e1512-9. Epub 2012 Nov 12 doi: 10.1542/peds.2012-1147. PMID: 23147980
The role of the hypothalamic-pituitary-adrenal axis dysfunction in the pathophysiology of alcohol misuse and suicidal behavior in adolescents.
Sher L
Int J Adolesc Med Health 2007 Jan-Mar;19(1):3-9. doi: 10.1515/ijamh.2007.19.1.3. PMID: 17458318

Therapy

Adrenal insufficiency in patients with Prader-Willi syndrome.
Kusz MJ, Gawlik AM
Front Endocrinol (Lausanne) 2022;13:1021704. Epub 2022 Nov 17 doi: 10.3389/fendo.2022.1021704. PMID: 36465638Free PMC Article
Hypothalamic-pituitary-adrenal axis suppression and intranasal corticosteroid use: A systematic review and meta-analysis.
Sampieri G, Namavarian A, Lee JJW, Hamour AF, Lee JM
Int Forum Allergy Rhinol 2022 Jan;12(1):11-27. Epub 2021 Jul 14 doi: 10.1002/alr.22863. PMID: 34260153
Environmental factors in the development and progression of late-onset Alzheimer's disease.
Wainaina MN, Chen Z, Zhong C
Neurosci Bull 2014 Apr;30(2):253-70. Epub 2014 Mar 24 doi: 10.1007/s12264-013-1425-9. PMID: 24664867Free PMC Article
Hypothalamic-pituitary-adrenal axis suppression in asthmatic school children.
Zöllner EW, Lombard CJ, Galal U, Hough FS, Irusen EM, Weinberg E
Pediatrics 2012 Dec;130(6):e1512-9. Epub 2012 Nov 12 doi: 10.1542/peds.2012-1147. PMID: 23147980
Model-based therapeutic correction of hypothalamic-pituitary-adrenal axis dysfunction.
Ben-Zvi A, Vernon SD, Broderick G
PLoS Comput Biol 2009 Jan;5(1):e1000273. Epub 2009 Jan 23 doi: 10.1371/journal.pcbi.1000273. PMID: 19165314Free PMC Article

Prognosis

Examining the interrelationships between mindfulness-based interventions, depression, inflammation, and cancer survival.
Marinovic DA, Hunter RL
CA Cancer J Clin 2022 Sep;72(5):490-502. Epub 2022 Jun 16 doi: 10.3322/caac.21733. PMID: 35709081
Thyroid complications of SARS and coronavirus disease 2019 (COVID-19).
Speer G, Somogyi P
Endocr J 2021 Feb 28;68(2):129-136. Epub 2021 Jan 19 doi: 10.1507/endocrj.EJ20-0443. PMID: 33473054
Hypothalamic-pituitary-adrenal axis suppression in asthmatic school children.
Zöllner EW, Lombard CJ, Galal U, Hough FS, Irusen EM, Weinberg E
Pediatrics 2012 Dec;130(6):e1512-9. Epub 2012 Nov 12 doi: 10.1542/peds.2012-1147. PMID: 23147980
Preconceptional stress and racial disparities in preterm birth: an overview.
Kramer MR, Hogue CJ, Dunlop AL, Menon R
Acta Obstet Gynecol Scand 2011 Dec;90(12):1307-16. Epub 2011 May 20 doi: 10.1111/j.1600-0412.2011.01136.x. PMID: 21446927Free PMC Article
Model-based therapeutic correction of hypothalamic-pituitary-adrenal axis dysfunction.
Ben-Zvi A, Vernon SD, Broderick G
PLoS Comput Biol 2009 Jan;5(1):e1000273. Epub 2009 Jan 23 doi: 10.1371/journal.pcbi.1000273. PMID: 19165314Free PMC Article

Clinical prediction guides

Hypothalamic-pituitary-adrenal axis suppression and intranasal corticosteroid use: A systematic review and meta-analysis.
Sampieri G, Namavarian A, Lee JJW, Hamour AF, Lee JM
Int Forum Allergy Rhinol 2022 Jan;12(1):11-27. Epub 2021 Jul 14 doi: 10.1002/alr.22863. PMID: 34260153
Psychological sequelae of myocardial infarction.
Kumar M, Nayak PK
Biomed Pharmacother 2017 Nov;95:487-496. Epub 2017 Sep 12 doi: 10.1016/j.biopha.2017.08.109. PMID: 28866415
DHEA, DHEAS and PCOS.
Goodarzi MO, Carmina E, Azziz R
J Steroid Biochem Mol Biol 2015 Jan;145:213-25. Epub 2014 Jul 5 doi: 10.1016/j.jsbmb.2014.06.003. PMID: 25008465
Hypothalamic-pituitary-adrenal axis suppression in asthmatic school children.
Zöllner EW, Lombard CJ, Galal U, Hough FS, Irusen EM, Weinberg E
Pediatrics 2012 Dec;130(6):e1512-9. Epub 2012 Nov 12 doi: 10.1542/peds.2012-1147. PMID: 23147980
Hypothalamic-pituitary-adrenal axis dysfunction in chronic fatigue syndrome.
Papadopoulos AS, Cleare AJ
Nat Rev Endocrinol 2011 Sep 27;8(1):22-32. doi: 10.1038/nrendo.2011.153. PMID: 21946893

Recent systematic reviews

Early Morning Cortisol Level as a Predictive Factor for Long-Term Glucocorticoid Replacement After Pituitary Surgery: A Systematic Review and Meta-Analysis.
Abdollahifard S, Taherifard E, Sadeghi A, Farrokhi A, Cohen-Gadol AA, Palmisciano P
World Neurosurg 2023 Aug;176:168-178. Epub 2023 May 16 doi: 10.1016/j.wneu.2023.05.029. PMID: 37201788
Potential peripheral biomarkers associated with the emergence and presence of posttraumatic stress disorder symptomatology: A systematic review.
Sbisa AM, Madden K, Toben C, McFarlane AC, Dell L, Lawrence-Wood E
Psychoneuroendocrinology 2023 Jan;147:105954. Epub 2022 Oct 20 doi: 10.1016/j.psyneuen.2022.105954. PMID: 36308820
Hypothalamic-pituitary-adrenal axis suppression and intranasal corticosteroid use: A systematic review and meta-analysis.
Sampieri G, Namavarian A, Lee JJW, Hamour AF, Lee JM
Int Forum Allergy Rhinol 2022 Jan;12(1):11-27. Epub 2021 Jul 14 doi: 10.1002/alr.22863. PMID: 34260153

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