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Bone mineral density quantitative trait locus 8(BMND8)

MedGen UID:
394842
Concept ID:
C2678504
Finding
Synonym: BMND8
 
OMIM®: 611739

Recent clinical studies

Etiology

Kemper KE, Sidorenko J, Wang H, Hayes BJ, Wray NR, Yengo L, Keller MC, Goddard M, Visscher PM
Nat Commun 2024 May 6;15(1):3776. doi: 10.1038/s41467-024-47802-7. PMID: 38710707Free PMC Article
Yu XH, Yang YQ, Cao RR, Cai MK, Zhang L, Deng FY, Lei SF
Hum Mol Genet 2021 Oct 13;30(21):1932-1940. doi: 10.1093/hmg/ddab158. PMID: 34132789
Trajanoska K, Seppala LJ, Medina-Gomez C, Hsu YH, Zhou S, van Schoor NM, de Groot LCPGM, Karasik D, Richards JB, Kiel DP, Uitterlinden AG, Perry JRB, van der Velde N, Day FR, Rivadeneira F
Commun Biol 2020 Sep 30;3(1):543. doi: 10.1038/s42003-020-01256-x. PMID: 32999390Free PMC Article
Liu L, Zhao M, Xie ZG, Liu J, Peng HP, Pei YF, Sun HP, Zhang L
Front Endocrinol (Lausanne) 2020;11:243. Epub 2020 Apr 22 doi: 10.3389/fendo.2020.00243. PMID: 32390946Free PMC Article
Liu CT, Estrada K, Yerges-Armstrong LM, Amin N, Evangelou E, Li G, Minster RL, Carless MA, Kammerer CM, Oei L, Zhou Y, Alonso N, Dailiana Z, Eriksson J, García-Giralt N, Giroux S, Husted LB, Khusainova RI, Koromila T, Kung AW, Lewis JR, Masi L, Mencej-Bedrac S, Nogues X, Patel MS, Prezelj J, Richards JB, Sham PC, Spector T, Vandenput L, Xiao SM, Zheng HF, Zhu K, Balcells S, Brandi ML, Frost M, Goltzman D, González-Macías J, Karlsson M, Khusnutdinova EK, Kollia P, Langdahl BL, Ljunggren O, Lorentzon M, Marc J, Mellström D, Ohlsson C, Olmos JM, Ralston SH, Riancho JA, Rousseau F, Urreizti R, Van Hul W, Zarrabeitia MT, Castano-Betancourt M, Demissie S, Grundberg E, Herrera L, Kwan T, Medina-Gómez C, Pastinen T, Sigurdsson G, Thorleifsson G, Vanmeurs JB, Blangero J, Hofman A, Liu Y, Mitchell BD, O'Connell JR, Oostra BA, Rotter JI, Stefansson K, Streeten EA, Styrkarsdottir U, Thorsteinsdottir U, Tylavsky FA, Uitterlinden A, Cauley JA, Harris TB, Ioannidis JP, Psaty BM, Robbins JA, Zillikens MC, Vanduijn CM, Prince RL, Karasik D, Rivadeneira F, Kiel DP, Cupples LA, Hsu YH
J Bone Miner Res 2012 Oct;27(10):2051-64. doi: 10.1002/jbmr.1679. PMID: 22692763Free PMC Article

Diagnosis

Zhang Z, Duan Y, Huo J
Calcif Tissue Int 2024 Feb;114(2):147-156. Epub 2023 Dec 10 doi: 10.1007/s00223-023-01160-6. PMID: 38071623
Rivadeneira F, Styrkársdottir U, Estrada K, Halldórsson BV, Hsu YH, Richards JB, Zillikens MC, Kavvoura FK, Amin N, Aulchenko YS, Cupples LA, Deloukas P, Demissie S, Grundberg E, Hofman A, Kong A, Karasik D, van Meurs JB, Oostra B, Pastinen T, Pols HA, Sigurdsson G, Soranzo N, Thorleifsson G, Thorsteinsdottir U, Williams FM, Wilson SG, Zhou Y, Ralston SH, van Duijn CM, Spector T, Kiel DP, Stefansson K, Ioannidis JP, Uitterlinden AG; Genetic Factors for Osteoporosis (GEFOS) Consortium
Nat Genet 2009 Nov;41(11):1199-206. Epub 2009 Oct 4 doi: 10.1038/ng.446. PMID: 19801982Free PMC Article

Therapy

Kemper KE, Sidorenko J, Wang H, Hayes BJ, Wray NR, Yengo L, Keller MC, Goddard M, Visscher PM
Nat Commun 2024 May 6;15(1):3776. doi: 10.1038/s41467-024-47802-7. PMID: 38710707Free PMC Article
Zhang Z, Duan Y, Huo J
Calcif Tissue Int 2024 Feb;114(2):147-156. Epub 2023 Dec 10 doi: 10.1007/s00223-023-01160-6. PMID: 38071623
Yu XH, Yang YQ, Cao RR, Cai MK, Zhang L, Deng FY, Lei SF
Hum Mol Genet 2021 Oct 13;30(21):1932-1940. doi: 10.1093/hmg/ddab158. PMID: 34132789
Oei L, Estrada K, Duncan EL, Christiansen C, Liu CT, Langdahl BL, Obermayer-Pietsch B, Riancho JA, Prince RL, van Schoor NM, McCloskey E, Hsu YH, Evangelou E, Ntzani E, Evans DM, Alonso N, Husted LB, Valero C, Hernandez JL, Lewis JR, Kaptoge SK, Zhu K, Cupples LA, Medina-Gómez C, Vandenput L, Kim GS, Hun Lee S, Castaño-Betancourt MC, Oei EH, Martinez J, Daroszewska A, van der Klift M, Mellström D, Herrera L, Karlsson MK, Hofman A, Ljunggren Ö, Pols HA, Stolk L, van Meurs JB, Ioannidis JP, Zillikens MC, Lips P, Karasik D, Uitterlinden AG, Styrkarsdottir U, Brown MA, Koh JM, Richards JB, Reeve J, Ohlsson C, Ralston SH, Kiel DP, Rivadeneira F
Bone 2014 Feb;59:20-7. PMID: 24516880Free PMC Article

Prognosis

Liu L, Zhao M, Xie ZG, Liu J, Peng HP, Pei YF, Sun HP, Zhang L
Front Endocrinol (Lausanne) 2020;11:243. Epub 2020 Apr 22 doi: 10.3389/fendo.2020.00243. PMID: 32390946Free PMC Article
Hsu YH, Estrada K, Evangelou E, Ackert-Bicknell C, Akesson K, Beck T, Brown SJ, Capellini T, Carbone L, Cauley J, Cheung CL, Cummings SR, Czerwinski S, Demissie S, Econs M, Evans D, Farber C, Gautvik K, Harris T, Kammerer C, Kemp J, Koller DL, Kung A, Lawlor D, Lee M, Lorentzon M, McGuigan F, Medina-Gomez C, Mitchell B, Newman A, Nielson C, Ohlsson C, Peacock M, Reppe S, Richards JB, Robbins J, Sigurdsson G, Spector TD, Stefansson K, Streeten E, Styrkarsdottir U, Tobias J, Trajanoska K, Uitterlinden A, Vandenput L, Wilson SG, Yerges-Armstrong L, Young M, Zillikens MC, Rivadeneira F, Kiel DP, Karasik D
J Bone Miner Res 2019 Jul;34(7):1284-1296. Epub 2019 Mar 19 doi: 10.1002/jbmr.3698. PMID: 30888730Free PMC Article
Martínez-Gil N, Roca-Ayats N, Monistrol-Mula A, García-Giralt N, Díez-Pérez A, Nogués X, Mellibovsky L, Grinberg D, Balcells S
Sci Rep 2018 Jul 19;8(1):10951. doi: 10.1038/s41598-018-29242-8. PMID: 30026596Free PMC Article
Estrada K, Styrkarsdottir U, Evangelou E, Hsu YH, Duncan EL, Ntzani EE, Oei L, Albagha OM, Amin N, Kemp JP, Koller DL, Li G, Liu CT, Minster RL, Moayyeri A, Vandenput L, Willner D, Xiao SM, Yerges-Armstrong LM, Zheng HF, Alonso N, Eriksson J, Kammerer CM, Kaptoge SK, Leo PJ, Thorleifsson G, Wilson SG, Wilson JF, Aalto V, Alen M, Aragaki AK, Aspelund T, Center JR, Dailiana Z, Duggan DJ, Garcia M, Garcia-Giralt N, Giroux S, Hallmans G, Hocking LJ, Husted LB, Jameson KA, Khusainova R, Kim GS, Kooperberg C, Koromila T, Kruk M, Laaksonen M, Lacroix AZ, Lee SH, Leung PC, Lewis JR, Masi L, Mencej-Bedrac S, Nguyen TV, Nogues X, Patel MS, Prezelj J, Rose LM, Scollen S, Siggeirsdottir K, Smith AV, Svensson O, Trompet S, Trummer O, van Schoor NM, Woo J, Zhu K, Balcells S, Brandi ML, Buckley BM, Cheng S, Christiansen C, Cooper C, Dedoussis G, Ford I, Frost M, Goltzman D, González-Macías J, Kähönen M, Karlsson M, Khusnutdinova E, Koh JM, Kollia P, Langdahl BL, Leslie WD, Lips P, Ljunggren Ö, Lorenc RS, Marc J, Mellström D, Obermayer-Pietsch B, Olmos JM, Pettersson-Kymmer U, Reid DM, Riancho JA, Ridker PM, Rousseau F, Slagboom PE, Tang NL, Urreizti R, Van Hul W, Viikari J, Zarrabeitia MT, Aulchenko YS, Castano-Betancourt M, Grundberg E, Herrera L, Ingvarsson T, Johannsdottir H, Kwan T, Li R, Luben R, Medina-Gómez C, Palsson ST, Reppe S, Rotter JI, Sigurdsson G, van Meurs JB, Verlaan D, Williams FM, Wood AR, Zhou Y, Gautvik KM, Pastinen T, Raychaudhuri S, Cauley JA, Chasman DI, Clark GR, Cummings SR, Danoy P, Dennison EM, Eastell R, Eisman JA, Gudnason V, Hofman A, Jackson RD, Jones G, Jukema JW, Khaw KT, Lehtimäki T, Liu Y, Lorentzon M, McCloskey E, Mitchell BD, Nandakumar K, Nicholson GC, Oostra BA, Peacock M, Pols HA, Prince RL, Raitakari O, Reid IR, Robbins J, Sambrook PN, Sham PC, Shuldiner AR, Tylavsky FA, van Duijn CM, Wareham NJ, Cupples LA, Econs MJ, Evans DM, Harris TB, Kung AW, Psaty BM, Reeve J, Spector TD, Streeten EA, Zillikens MC, Thorsteinsdottir U, Ohlsson C, Karasik D, Richards JB, Brown MA, Stefansson K, Uitterlinden AG, Ralston SH, Ioannidis JP, Kiel DP, Rivadeneira F
Nat Genet 2012 Apr 15;44(5):491-501. doi: 10.1038/ng.2249. PMID: 22504420Free PMC Article
Szumska D, Benes H, Kang P, Weinstein RS, Jilka RL, Manolagas SC, Shmookler Reis RJ
Bone 2007 Mar;40(3):758-66. Epub 2006 Dec 19 doi: 10.1016/j.bone.2006.10.012. PMID: 17185055Free PMC Article

Clinical prediction guides

Zhang Z, Duan Y, Huo J
Calcif Tissue Int 2024 Feb;114(2):147-156. Epub 2023 Dec 10 doi: 10.1007/s00223-023-01160-6. PMID: 38071623
Yu XH, Yang YQ, Cao RR, Cai MK, Zhang L, Deng FY, Lei SF
Hum Mol Genet 2021 Oct 13;30(21):1932-1940. doi: 10.1093/hmg/ddab158. PMID: 34132789
Trajanoska K, Seppala LJ, Medina-Gomez C, Hsu YH, Zhou S, van Schoor NM, de Groot LCPGM, Karasik D, Richards JB, Kiel DP, Uitterlinden AG, Perry JRB, van der Velde N, Day FR, Rivadeneira F
Commun Biol 2020 Sep 30;3(1):543. doi: 10.1038/s42003-020-01256-x. PMID: 32999390Free PMC Article
Liu CT, Estrada K, Yerges-Armstrong LM, Amin N, Evangelou E, Li G, Minster RL, Carless MA, Kammerer CM, Oei L, Zhou Y, Alonso N, Dailiana Z, Eriksson J, García-Giralt N, Giroux S, Husted LB, Khusainova RI, Koromila T, Kung AW, Lewis JR, Masi L, Mencej-Bedrac S, Nogues X, Patel MS, Prezelj J, Richards JB, Sham PC, Spector T, Vandenput L, Xiao SM, Zheng HF, Zhu K, Balcells S, Brandi ML, Frost M, Goltzman D, González-Macías J, Karlsson M, Khusnutdinova EK, Kollia P, Langdahl BL, Ljunggren O, Lorentzon M, Marc J, Mellström D, Ohlsson C, Olmos JM, Ralston SH, Riancho JA, Rousseau F, Urreizti R, Van Hul W, Zarrabeitia MT, Castano-Betancourt M, Demissie S, Grundberg E, Herrera L, Kwan T, Medina-Gómez C, Pastinen T, Sigurdsson G, Thorleifsson G, Vanmeurs JB, Blangero J, Hofman A, Liu Y, Mitchell BD, O'Connell JR, Oostra BA, Rotter JI, Stefansson K, Streeten EA, Styrkarsdottir U, Thorsteinsdottir U, Tylavsky FA, Uitterlinden A, Cauley JA, Harris TB, Ioannidis JP, Psaty BM, Robbins JA, Zillikens MC, Vanduijn CM, Prince RL, Karasik D, Rivadeneira F, Kiel DP, Cupples LA, Hsu YH
J Bone Miner Res 2012 Oct;27(10):2051-64. doi: 10.1002/jbmr.1679. PMID: 22692763Free PMC Article
Shaffer JR, Kammerer CM, Bruder JM, Cole SA, Dyer TD, Almasy L, Maccluer JW, Blangero J, Bauer RL, Mitchell BD
Calcif Tissue Int 2009 Feb;84(2):75-84. Epub 2008 Dec 9 doi: 10.1007/s00223-008-9197-3. PMID: 19067020Free PMC Article

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