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Metastatic Ocular Melanoma

MedGen UID:: 1732756
•Concept ID:: C2242657
•: Neoplastic Process

Definition

Ocular melanoma that has spread from its original site of growth to another anatomic site. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVMetastatic Ocular Melanoma

Disease
- Neoplasm
  - Malignant neoplastic disease
    - Melanoma
      - Metastatic melanoma
        Metastatic Non-Cutaneous Melanoma
        Metastatic Ocular Melanoma
        Locally Advanced Ocular Melanoma
        Metastatic Uveal Melanoma
        Advanced Uveal Melanoma
        Uveal Melanoma Metastatic in the Liver
        Metastatic Choroid Melanoma

Professional guidelines

PubMed

Combined surgical resection and radiofrequency ablation as treatment for metastatic ocular melanoma.

Derek E, Matsuoka L, Alexopoulos S, Fedenko A, Genyk Y, Selby R
Surg Today 2013 Apr;43(4):367-71. Epub 2012 Jul 6 doi: 10.1007/s00595-012-0244-3. PMID: 22766897

Regional treatment options for patients with ocular melanoma metastatic to the liver.

Feldman ED, Pingpank JF, Alexander HR Jr
Ann Surg Oncol 2004 Mar;11(3):290-7. doi: 10.1245/aso.2004.07.004. PMID: 14993024

Treatment of uveal melanoma metastatic to the liver: a review of the M. D. Anderson Cancer Center experience and prognostic factors.

Bedikian AY, Legha SS, Mavligit G, Carrasco CH, Khorana S, Plager C, Papadopoulos N, Benjamin RS
Cancer 1995 Nov 1;76(9):1665-70. doi: 10.1002/1097-0142(19951101)76:9<1665::aid-cncr2820760925>3.0.co;2-j. PMID: 8635073

See all (3)

Recent clinical studies

Etiology

Treatment of metastatic uveal melanoma with adoptive transfer of tumour-infiltrating lymphocytes: a single-centre, two-stage, single-arm, phase 2 study.

Chandran SS, Somerville RPT, Yang JC, Sherry RM, Klebanoff CA, Goff SL, Wunderlich JR, Danforth DN, Zlott D, Paria BC, Sabesan AC, Srivastava AK, Xi L, Pham TH, Raffeld M, White DE, Toomey MA, Rosenberg SA, Kammula US
Lancet Oncol 2017 Jun;18(6):792-802. Epub 2017 Apr 7 doi: 10.1016/S1470-2045(17)30251-6. PMID: 28395880 Free PMC Article

Metastatic melanoma to the liver: a contemporary and comprehensive review of surgical, systemic, and regional therapeutic options.

Agarwala SS, Eggermont AM, O'Day S, Zager JS
Cancer 2014 Mar 15;120(6):781-9. Epub 2013 Dec 2 doi: 10.1002/cncr.28480. PMID: 24301420

Combined surgical resection and radiofrequency ablation as treatment for metastatic ocular melanoma.

Derek E, Matsuoka L, Alexopoulos S, Fedenko A, Genyk Y, Selby R
Surg Today 2013 Apr;43(4):367-71. Epub 2012 Jul 6 doi: 10.1007/s00595-012-0244-3. PMID: 22766897

Germline BAP1 inactivation is preferentially associated with metastatic ocular melanoma and cutaneous-ocular melanoma families.

Njauw CN, Kim I, Piris A, Gabree M, Taylor M, Lane AM, DeAngelis MM, Gragoudas E, Duncan LM, Tsao H
PLoS One 2012;7(4):e35295. Epub 2012 Apr 24 doi: 10.1371/journal.pone.0035295. PMID: 22545102 Free PMC Article

Qualitative assessment of undetectable melanin distribution in lightly pigmented irides.

Baranoski GV, Lam MW
J Biomed Opt 2007 May-Jun;12(3):030501. doi: 10.1117/1.2747205. PMID: 17614705

See all (14)

Diagnosis

Combined surgical resection and radiofrequency ablation as treatment for metastatic ocular melanoma.

Derek E, Matsuoka L, Alexopoulos S, Fedenko A, Genyk Y, Selby R
Surg Today 2013 Apr;43(4):367-71. Epub 2012 Jul 6 doi: 10.1007/s00595-012-0244-3. PMID: 22766897

Qualitative assessment of undetectable melanin distribution in lightly pigmented irides.

Baranoski GV, Lam MW
J Biomed Opt 2007 May-Jun;12(3):030501. doi: 10.1117/1.2747205. PMID: 17614705

Metastatic ocular melanoma to the kidney 20 years after initial diagnosis.

Levin BM, Boulos FI, Herrell SD
Urology 2005 Sep;66(3):658. doi: 10.1016/j.urology.2005.03.035. PMID: 16140107

Indications for surgical resection of metastatic ocular melanoma. A case report and review of the literature.

Cunningham JD, Cirincione E, Ryan A, Canin-Endres J, Brower S
Int J Pancreatol 1998 Aug;24(1):49-53. doi: 10.1007/BF02787531. PMID: 9746890

The prevalence and location of metastases from ocular melanoma: imaging study in 110 patients.

Lorigan JG, Wallace S, Mavligit GM
AJR Am J Roentgenol 1991 Dec;157(6):1279-81. doi: 10.2214/ajr.157.6.1950883. PMID: 1950883

See all (13)

Therapy

Chemosaturation of the Liver - an Update.

Ebel S, Struck MF, van Boemmel F, Beeskow AB, Gößmann H, Denecke T
Rofo 2023 Jan;195(1):30-37. Epub 2022 Aug 17 doi: 10.1055/a-1858-3418. PMID: 35977553

Treatment of metastatic uveal melanoma with adoptive transfer of tumour-infiltrating lymphocytes: a single-centre, two-stage, single-arm, phase 2 study.

Metastatic melanoma to the liver: a contemporary and comprehensive review of surgical, systemic, and regional therapeutic options.

Agarwala SS, Eggermont AM, O'Day S, Zager JS
Cancer 2014 Mar 15;120(6):781-9. Epub 2013 Dec 2 doi: 10.1002/cncr.28480. PMID: 24301420

Isolated hepatic perfusion for metastatic melanoma.

Yamamoto M, Zager JS
J Surg Oncol 2014 Mar;109(4):383-8. Epub 2013 Oct 25 doi: 10.1002/jso.23474. PMID: 24166748

A pilot study of bevacizumab and interferon-α2b in ocular melanoma.

Guenterberg KD, Grignol VP, Relekar KV, Varker KA, Chen HX, Kendra KL, Olencki TE, Carson WE 3rd
Am J Clin Oncol 2011 Feb;34(1):87-91. doi: 10.1097/COC.0b013e3181d2ed67. PMID: 20458209 Free PMC Article

See all (19)

Prognosis

Isolated hepatic perfusion for metastatic melanoma.

Yamamoto M, Zager JS
J Surg Oncol 2014 Mar;109(4):383-8. Epub 2013 Oct 25 doi: 10.1002/jso.23474. PMID: 24166748

Combined surgical resection and radiofrequency ablation as treatment for metastatic ocular melanoma.

Derek E, Matsuoka L, Alexopoulos S, Fedenko A, Genyk Y, Selby R
Surg Today 2013 Apr;43(4):367-71. Epub 2012 Jul 6 doi: 10.1007/s00595-012-0244-3. PMID: 22766897

A pilot study of bevacizumab and interferon-α2b in ocular melanoma.

Metastatic ocular melanoma.

Abramson DH, Kerestzes R, Shamonki J
Arch Ophthalmol 2004 Apr;122(4):658-9. doi: 10.1001/archopht.122.4.658. PMID: 15078690

The prevalence and location of metastases from ocular melanoma: imaging study in 110 patients.

Lorigan JG, Wallace S, Mavligit GM
AJR Am J Roentgenol 1991 Dec;157(6):1279-81. doi: 10.2214/ajr.157.6.1950883. PMID: 1950883

See all (19)

Clinical prediction guides

Metastatic melanoma to the liver: a contemporary and comprehensive review of surgical, systemic, and regional therapeutic options.

Agarwala SS, Eggermont AM, O'Day S, Zager JS
Cancer 2014 Mar 15;120(6):781-9. Epub 2013 Dec 2 doi: 10.1002/cncr.28480. PMID: 24301420

A pilot study of bevacizumab and interferon-α2b in ocular melanoma.

Clinical study of [123I] N-(2-diethylaminoethyl)-4-iodobenzamide in the diagnosis of primary and metastatic ocular melanoma.

Bacin F, Michelot J, Bonafous J, Veyre A, Moreau MF, Kemeny JL, Chossat F, Bekhechi D
Acta Ophthalmol Scand 1998 Feb;76(1):56-61. doi: 10.1034/j.1600-0420.1998.760110.x. PMID: 9541435

Treatment of uveal melanoma metastatic to the liver: a review of the M. D. Anderson Cancer Center experience and prognostic factors.

Survival in metastatic ocular melanoma.

Rajpal S, Moore R, Karakousis CP
Cancer 1983 Jul 15;52(2):334-6. doi: 10.1002/1097-0142(19830715)52:2<334::aid-cncr2820520225>3.0.co;2-e. PMID: 6190546

See all (6)

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Metastatic Ocular Melanoma

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Supplemental Content

Table of contents

Practice guidelines

Related information

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