U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Angioma

MedGen UID:
409516
•Concept ID:
C1959588
•
Neoplastic Process
Synonym: Angiomas

Definition

A vascular anomaly due to proliferation of blood or lymphatic vessels that forms a tumor-like mass. Vessels in the angioma may or may not be dilated. [from MeSH]

Professional guidelines

PubMed

S2k guideline: Laser therapy of the skin.
Paasch U, Zidane M, Baron JM, Bund T, Cappius HJ, Drosner M, Feise K, Fischer T, Gauglitz G, Gerber PA, Grunewald S, Herberger K, Jung A, Karsai S, Kautz G, Philipp C, Schädel D, Seitz AT, Nast A
J Dtsch Dermatol Ges 2022 Sep;20(9):1248-1267. Epub 2022 Sep 13 doi: 10.1111/ddg.14879. PMID: 36098675
Clinical Management of Cavernous Malformations.
Flemming KD
Curr Cardiol Rep 2017 Oct 18;19(12):122. doi: 10.1007/s11886-017-0931-1. PMID: 29046973
Synopsis of Guidelines for the Clinical Management of Cerebral Cavernous Malformations: Consensus Recommendations Based on Systematic Literature Review by the Angioma Alliance Scientific Advisory Board Clinical Experts Panel.
Akers A, Al-Shahi Salman R, A Awad I, Dahlem K, Flemming K, Hart B, Kim H, Jusue-Torres I, Kondziolka D, Lee C, Morrison L, Rigamonti D, Rebeiz T, Tournier-Lasserve E, Waggoner D, Whitehead K
Neurosurgery 2017 May 1;80(5):665-680. doi: 10.1093/neuros/nyx091. PMID: 28387823Free PMC Article

Recent clinical studies

Etiology

Treatment practices and response in kaposiform hemangioendothelioma: A multicenter cohort study.
Borst AJ, Eng W, Griffin M, Ricci KW, Engel E, Adams DM, Dayneka J, Cohen-Cutler SJ, Andreoli SM, Wu MD, Wheeler AP, Heym KM, Crary SE, Nakano TA, Schulte RR, Setty BA, McLean TW, Pahl KS, Intzes S, Pateva I, Teitelbaum M, Zong Z, Li Y, Jeng MR
Pediatr Blood Cancer 2024 Mar;71(3):e30779. Epub 2023 Dec 10 doi: 10.1002/pbc.30779. PMID: 38073018
Clinical Management of Cavernous Malformations.
Flemming KD
Curr Cardiol Rep 2017 Oct 18;19(12):122. doi: 10.1007/s11886-017-0931-1. PMID: 29046973
Developmental venous anomalies.
Mooney MA, Zabramski JM
Handb Clin Neurol 2017;143:279-282. doi: 10.1016/B978-0-444-63640-9.00026-6. PMID: 28552150
Synopsis of Guidelines for the Clinical Management of Cerebral Cavernous Malformations: Consensus Recommendations Based on Systematic Literature Review by the Angioma Alliance Scientific Advisory Board Clinical Experts Panel.
Akers A, Al-Shahi Salman R, A Awad I, Dahlem K, Flemming K, Hart B, Kim H, Jusue-Torres I, Kondziolka D, Lee C, Morrison L, Rigamonti D, Rebeiz T, Tournier-Lasserve E, Waggoner D, Whitehead K
Neurosurgery 2017 May 1;80(5):665-680. doi: 10.1093/neuros/nyx091. PMID: 28387823Free PMC Article
Sturge-Weber syndrome.
Baselga E
Semin Cutan Med Surg 2004 Jun;23(2):87-98. doi: 10.1016/j.sder.2004.01.002. PMID: 15295918

Diagnosis

Angioma serpiginosum.
Kanji A, Laguda B, Roberts N
Br J Hosp Med (Lond) 2023 Jul 2;84(7):1. Epub 2023 Jul 18 doi: 10.12968/hmed.2023.0030. PMID: 37490440
Neonatal incontinentia pigmenti.
Herzum A, Viglizzo G, Gariazzo L, Garibeh E, Occella C
Ital J Dermatol Venerol 2023 Apr;158(2):164-166. Epub 2023 Mar 17 doi: 10.23736/S2784-8671.23.07474-1. PMID: 36930459
Sturge-Weber syndrome: from the past to the present.
Sudarsanam A, Ardern-Holmes SL
Eur J Paediatr Neurol 2014 May;18(3):257-66. Epub 2013 Nov 7 doi: 10.1016/j.ejpn.2013.10.003. PMID: 24275166
Sturge-Weber syndrome.
Nabbout R, Juhász C
Handb Clin Neurol 2013;111:315-21. doi: 10.1016/B978-0-444-52891-9.00037-3. PMID: 23622182
Eruptive pseudoangiomatosis.
Yang JH, Kim JW, Park HS, Jang SJ, Choi JC
J Dermatol 2006 Dec;33(12):873-6. doi: 10.1111/j.1346-8138.2006.00199.x. PMID: 17169093

Therapy

Comorbidities in Angioedema Due to C1-Inhibitor Deficiency: An Italian Survey.
Zanichelli A, Senter R, Merlo A, Gidaro A, Popescu Janu V, Cogliati CB, Cancian M
J Allergy Clin Immunol Pract 2024 Apr;12(4):1029-1036. Epub 2024 Jan 3 doi: 10.1016/j.jaip.2023.12.046. PMID: 38182098
A retrospective 10 years- experience overview of dye laser treatments for vascular pathologies.
Giovanni C, Marina PB, Tiziano Z
Skin Res Technol 2023 Aug;29(8):e13427. doi: 10.1111/srt.13427. PMID: 37632184Free PMC Article
Safety and efficacy of propranolol for treatment of familial cerebral cavernous malformations (Treat_CCM): a randomised, open-label, blinded-endpoint, phase 2 pilot trial.
Lanfranconi S, Scola E, Meessen JMTA, Pallini R, Bertani GA, Al-Shahi Salman R, Dejana E, Latini R; Treat_CCM Investigators
Lancet Neurol 2023 Jan;22(1):35-44. Epub 2022 Nov 17 doi: 10.1016/S1474-4422(22)00409-4. PMID: 36403580
Clinical Management of Cavernous Malformations.
Flemming KD
Curr Cardiol Rep 2017 Oct 18;19(12):122. doi: 10.1007/s11886-017-0931-1. PMID: 29046973
Synopsis of Guidelines for the Clinical Management of Cerebral Cavernous Malformations: Consensus Recommendations Based on Systematic Literature Review by the Angioma Alliance Scientific Advisory Board Clinical Experts Panel.
Akers A, Al-Shahi Salman R, A Awad I, Dahlem K, Flemming K, Hart B, Kim H, Jusue-Torres I, Kondziolka D, Lee C, Morrison L, Rigamonti D, Rebeiz T, Tournier-Lasserve E, Waggoner D, Whitehead K
Neurosurgery 2017 May 1;80(5):665-680. doi: 10.1093/neuros/nyx091. PMID: 28387823Free PMC Article

Prognosis

Littoral cell angioma of the spleen: A study of 10 cases case series and literature review.
Shen H, Zhu Y, Zhong J, Shen Y, Huang Y, Song P, He J, Zhou S, Wu X
Medicine (Baltimore) 2024 Mar 29;103(13):e37550. doi: 10.1097/MD.0000000000037550. PMID: 38552075Free PMC Article
Vascular neoplasms and non-neoplastic vascular lesions of the spleen.
Sangiorgio VFI, Arber DA
Semin Diagn Pathol 2021 Mar;38(2):154-158. Epub 2020 Jul 8 doi: 10.1053/j.semdp.2020.07.001. PMID: 32674844
Sturge-Weber syndrome: from the past to the present.
Sudarsanam A, Ardern-Holmes SL
Eur J Paediatr Neurol 2014 May;18(3):257-66. Epub 2013 Nov 7 doi: 10.1016/j.ejpn.2013.10.003. PMID: 24275166
Sturge-Weber syndrome.
Nabbout R, Juhász C
Handb Clin Neurol 2013;111:315-21. doi: 10.1016/B978-0-444-52891-9.00037-3. PMID: 23622182
Cerebral developmental venous anomalies.
San Millán Ruíz D, Gailloud P
Childs Nerv Syst 2010 Oct;26(10):1395-406. Epub 2010 Aug 12 doi: 10.1007/s00381-010-1253-4. PMID: 20703485

Clinical prediction guides

Littoral cell angioma of the spleen: A study of 10 cases case series and literature review.
Shen H, Zhu Y, Zhong J, Shen Y, Huang Y, Song P, He J, Zhou S, Wu X
Medicine (Baltimore) 2024 Mar 29;103(13):e37550. doi: 10.1097/MD.0000000000037550. PMID: 38552075Free PMC Article
Clinical characteristics of familial and sporadic pediatric cerebral cavernous malformations and outcomes.
Jaman E, Abdallah HM, Zhang X, Greene S
J Neurosurg Pediatr 2023 Oct 1;32(4):506-513. Epub 2023 Jul 21 doi: 10.3171/2023.5.PEDS22397. PMID: 37503918
Safety and efficacy of propranolol for treatment of familial cerebral cavernous malformations (Treat_CCM): a randomised, open-label, blinded-endpoint, phase 2 pilot trial.
Lanfranconi S, Scola E, Meessen JMTA, Pallini R, Bertani GA, Al-Shahi Salman R, Dejana E, Latini R; Treat_CCM Investigators
Lancet Neurol 2023 Jan;22(1):35-44. Epub 2022 Nov 17 doi: 10.1016/S1474-4422(22)00409-4. PMID: 36403580
The Bone Does Not Predict the Brain in Sturge-Weber Syndrome.
Warne RR, Carney OM, Wang G, Bhattacharya D, Chong WK, Aylett SE, Mankad K
AJNR Am J Neuroradiol 2018 Aug;39(8):1543-1549. Epub 2018 Jul 19 doi: 10.3174/ajnr.A5722. PMID: 30026385Free PMC Article
The Baller-Gerold syndrome.
Van Maldergem L, Verloes A, Lejeune L, Gillerot Y
J Med Genet 1992 Apr;29(4):266-8. doi: 10.1136/jmg.29.4.266. PMID: 1583650Free PMC Article

Recent systematic reviews

Radiation-Induced Cerebral Cavernous Malformations: A Single-Center Experience and Systematic Literature Review.
Koester SW, Rhodenhiser EG, Dabrowski SJ, Benner D, Rumalla K, Scherschinski L, Catapano JS, Graffeo CS, Srinivasan VM, Lawton MT
World Neurosurg 2023 Nov;179:222-232.e2. Epub 2023 Aug 17 doi: 10.1016/j.wneu.2023.08.036. PMID: 37595838
Treatment Modalities for Cherry Angiomas: A Systematic Review.
Buslach N, Foulad DP, Saedi N, Mesinkovska NA
Dermatol Surg 2020 Dec;46(12):1691-1697. doi: 10.1097/DSS.0000000000002791. PMID: 33252464
Synopsis of Guidelines for the Clinical Management of Cerebral Cavernous Malformations: Consensus Recommendations Based on Systematic Literature Review by the Angioma Alliance Scientific Advisory Board Clinical Experts Panel.
Akers A, Al-Shahi Salman R, A Awad I, Dahlem K, Flemming K, Hart B, Kim H, Jusue-Torres I, Kondziolka D, Lee C, Morrison L, Rigamonti D, Rebeiz T, Tournier-Lasserve E, Waggoner D, Whitehead K
Neurosurgery 2017 May 1;80(5):665-680. doi: 10.1093/neuros/nyx091. PMID: 28387823Free PMC Article
Treatment of kaposiform hemangioendothelioma and tufted angioma.
Liu XH, Li JY, Qu XH, Yan WL, Zhang L, Yang C, Zheng JW
Int J Cancer 2016 Oct 1;139(7):1658-66. Epub 2016 Jun 28 doi: 10.1002/ijc.30216. PMID: 27252149
Visual outcome in Sturge-Weber syndrome: a systematic review and Dutch multicentre cohort.
Koenraads Y, van Egmond-Ebbeling MB, de Boer JH, Imhof SM, Braun KP, Porro GL; SWS study group
Acta Ophthalmol 2016 Nov;94(7):638-645. Epub 2016 May 30 doi: 10.1111/aos.13074. PMID: 27238857

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...