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Angioma

MedGen UID:
409516
•Concept ID:
C1959588
•
Neoplastic Process
Synonym: Angiomas

Definition

A vascular anomaly due to proliferation of blood or lymphatic vessels that forms a tumor-like mass. Vessels in the angioma may or may not be dilated. [from MeSH]

Professional guidelines

PubMed

S2k guideline: Laser therapy of the skin.
Paasch U, Zidane M, Baron JM, Bund T, Cappius HJ, Drosner M, Feise K, Fischer T, Gauglitz G, Gerber PA, Grunewald S, Herberger K, Jung A, Karsai S, Kautz G, Philipp C, Schädel D, Seitz AT, Nast A
J Dtsch Dermatol Ges 2022 Sep;20(9):1248-1267. Epub 2022 Sep 13 doi: 10.1111/ddg.14879. PMID: 36098675
Clinical Management of Cavernous Malformations.
Flemming KD
Curr Cardiol Rep 2017 Oct 18;19(12):122. doi: 10.1007/s11886-017-0931-1. PMID: 29046973
Synopsis of Guidelines for the Clinical Management of Cerebral Cavernous Malformations: Consensus Recommendations Based on Systematic Literature Review by the Angioma Alliance Scientific Advisory Board Clinical Experts Panel.
Akers A, Al-Shahi Salman R, A Awad I, Dahlem K, Flemming K, Hart B, Kim H, Jusue-Torres I, Kondziolka D, Lee C, Morrison L, Rigamonti D, Rebeiz T, Tournier-Lasserve E, Waggoner D, Whitehead K
Neurosurgery 2017 May 1;80(5):665-680. doi: 10.1093/neuros/nyx091. PMID: 28387823Free PMC Article

Recent clinical studies

Etiology

The limitations of dermoscopy: false-positive and false-negative tumours.
Papageorgiou V, Apalla Z, Sotiriou E, Papageorgiou C, Lazaridou E, Vakirlis S, Ioannides D, Lallas A
J Eur Acad Dermatol Venereol 2018 Jun;32(6):879-888. Epub 2018 Jan 24 doi: 10.1111/jdv.14782. PMID: 29314288
Clinical Management of Cavernous Malformations.
Flemming KD
Curr Cardiol Rep 2017 Oct 18;19(12):122. doi: 10.1007/s11886-017-0931-1. PMID: 29046973
Developmental venous anomalies.
Mooney MA, Zabramski JM
Handb Clin Neurol 2017;143:279-282. doi: 10.1016/B978-0-444-63640-9.00026-6. PMID: 28552150
Synopsis of Guidelines for the Clinical Management of Cerebral Cavernous Malformations: Consensus Recommendations Based on Systematic Literature Review by the Angioma Alliance Scientific Advisory Board Clinical Experts Panel.
Akers A, Al-Shahi Salman R, A Awad I, Dahlem K, Flemming K, Hart B, Kim H, Jusue-Torres I, Kondziolka D, Lee C, Morrison L, Rigamonti D, Rebeiz T, Tournier-Lasserve E, Waggoner D, Whitehead K
Neurosurgery 2017 May 1;80(5):665-680. doi: 10.1093/neuros/nyx091. PMID: 28387823Free PMC Article
Sturge-Weber syndrome.
Baselga E
Semin Cutan Med Surg 2004 Jun;23(2):87-98. doi: 10.1016/j.sder.2004.01.002. PMID: 15295918

Diagnosis

Angioma serpiginosum.
Kanji A, Laguda B, Roberts N
Br J Hosp Med (Lond) 2023 Jul 2;84(7):1. Epub 2023 Jul 18 doi: 10.12968/hmed.2023.0030. PMID: 37490440
Neonatal incontinentia pigmenti.
Herzum A, Viglizzo G, Gariazzo L, Garibeh E, Occella C
Ital J Dermatol Venerol 2023 Apr;158(2):164-166. Epub 2023 Mar 17 doi: 10.23736/S2784-8671.23.07474-1. PMID: 36930459
The limitations of dermoscopy: false-positive and false-negative tumours.
Papageorgiou V, Apalla Z, Sotiriou E, Papageorgiou C, Lazaridou E, Vakirlis S, Ioannides D, Lallas A
J Eur Acad Dermatol Venereol 2018 Jun;32(6):879-888. Epub 2018 Jan 24 doi: 10.1111/jdv.14782. PMID: 29314288
Sturge-Weber syndrome: from the past to the present.
Sudarsanam A, Ardern-Holmes SL
Eur J Paediatr Neurol 2014 May;18(3):257-66. Epub 2013 Nov 7 doi: 10.1016/j.ejpn.2013.10.003. PMID: 24275166
Sturge-Weber syndrome.
Nabbout R, Juhász C
Handb Clin Neurol 2013;111:315-21. doi: 10.1016/B978-0-444-52891-9.00037-3. PMID: 23622182

Therapy

Sirolimus as initial therapy for kaposiform hemangioendothelioma and tufted angioma.
Wang H, Guo X, Duan Y, Zheng B, Gao Y
Pediatr Dermatol 2018 Sep;35(5):635-638. Epub 2018 Jul 12 doi: 10.1111/pde.13600. PMID: 29999213
Clinical Management of Cavernous Malformations.
Flemming KD
Curr Cardiol Rep 2017 Oct 18;19(12):122. doi: 10.1007/s11886-017-0931-1. PMID: 29046973
Synopsis of Guidelines for the Clinical Management of Cerebral Cavernous Malformations: Consensus Recommendations Based on Systematic Literature Review by the Angioma Alliance Scientific Advisory Board Clinical Experts Panel.
Akers A, Al-Shahi Salman R, A Awad I, Dahlem K, Flemming K, Hart B, Kim H, Jusue-Torres I, Kondziolka D, Lee C, Morrison L, Rigamonti D, Rebeiz T, Tournier-Lasserve E, Waggoner D, Whitehead K
Neurosurgery 2017 May 1;80(5):665-680. doi: 10.1093/neuros/nyx091. PMID: 28387823Free PMC Article
The clinical spectrum of kaposiform hemangioendothelioma and tufted angioma.
Croteau SE, Gupta D
Semin Cutan Med Surg 2016 Sep;35(3):147-52. doi: 10.12788/j.sder.2016.048. PMID: 27607323
Treatment of kaposiform hemangioendothelioma and tufted angioma.
Liu XH, Li JY, Qu XH, Yan WL, Zhang L, Yang C, Zheng JW
Int J Cancer 2016 Oct 1;139(7):1658-66. Epub 2016 Jun 28 doi: 10.1002/ijc.30216. PMID: 27252149

Prognosis

Perfusion and Permeability MRI Predicts Future Cavernous Angioma Hemorrhage and Growth.
Sone JY, Hobson N, Srinath A, Romanos SG, Li Y, Carrión-Penagos J, Shkoukani A, Stadnik A, Piedad K, Lightle R, Moore T, DeBiasse D, Bi D, Shenkar R, Carroll T, Ji Y, Girard R, Awad IA
J Magn Reson Imaging 2022 May;55(5):1440-1449. Epub 2021 Sep 24 doi: 10.1002/jmri.27935. PMID: 34558140Free PMC Article
Vascular neoplasms and non-neoplastic vascular lesions of the spleen.
Sangiorgio VFI, Arber DA
Semin Diagn Pathol 2021 Mar;38(2):154-158. Epub 2020 Jul 8 doi: 10.1053/j.semdp.2020.07.001. PMID: 32674844
Sturge-Weber syndrome: from the past to the present.
Sudarsanam A, Ardern-Holmes SL
Eur J Paediatr Neurol 2014 May;18(3):257-66. Epub 2013 Nov 7 doi: 10.1016/j.ejpn.2013.10.003. PMID: 24275166
Sturge-Weber syndrome.
Nabbout R, Juhász C
Handb Clin Neurol 2013;111:315-21. doi: 10.1016/B978-0-444-52891-9.00037-3. PMID: 23622182
Cerebral developmental venous anomalies.
San Millán Ruíz D, Gailloud P
Childs Nerv Syst 2010 Oct;26(10):1395-406. Epub 2010 Aug 12 doi: 10.1007/s00381-010-1253-4. PMID: 20703485

Clinical prediction guides

Clinical characteristics of familial and sporadic pediatric cerebral cavernous malformations and outcomes.
Jaman E, Abdallah HM, Zhang X, Greene S
J Neurosurg Pediatr 2023 Oct 1;32(4):506-513. Epub 2023 Jul 21 doi: 10.3171/2023.5.PEDS22397. PMID: 37503918
Perfusion and Permeability MRI Predicts Future Cavernous Angioma Hemorrhage and Growth.
Sone JY, Hobson N, Srinath A, Romanos SG, Li Y, Carrión-Penagos J, Shkoukani A, Stadnik A, Piedad K, Lightle R, Moore T, DeBiasse D, Bi D, Shenkar R, Carroll T, Ji Y, Girard R, Awad IA
J Magn Reson Imaging 2022 May;55(5):1440-1449. Epub 2021 Sep 24 doi: 10.1002/jmri.27935. PMID: 34558140Free PMC Article
The Bone Does Not Predict the Brain in Sturge-Weber Syndrome.
Warne RR, Carney OM, Wang G, Bhattacharya D, Chong WK, Aylett SE, Mankad K
AJNR Am J Neuroradiol 2018 Aug;39(8):1543-1549. Epub 2018 Jul 19 doi: 10.3174/ajnr.A5722. PMID: 30026385Free PMC Article
Cerebral developmental venous anomalies.
San Millán Ruíz D, Gailloud P
Childs Nerv Syst 2010 Oct;26(10):1395-406. Epub 2010 Aug 12 doi: 10.1007/s00381-010-1253-4. PMID: 20703485
Cavernous angioma: a clinical study of 35 cases with review of the literature.
Ebrahimi A, Etemadifar M, Ardestani PM, Maghzi AH, Jaffe S, Nejadnik H
Neurol Res 2009 Oct;31(8):785-93. doi: 10.1179/016164109X12445505689445. PMID: 19723446

Recent systematic reviews

Radiation-Induced Cerebral Cavernous Malformations: A Single-Center Experience and Systematic Literature Review.
Koester SW, Rhodenhiser EG, Dabrowski SJ, Benner D, Rumalla K, Scherschinski L, Catapano JS, Graffeo CS, Srinivasan VM, Lawton MT
World Neurosurg 2023 Nov;179:222-232.e2. Epub 2023 Aug 17 doi: 10.1016/j.wneu.2023.08.036. PMID: 37595838
Treatment Modalities for Cherry Angiomas: A Systematic Review.
Buslach N, Foulad DP, Saedi N, Mesinkovska NA
Dermatol Surg 2020 Dec;46(12):1691-1697. doi: 10.1097/DSS.0000000000002791. PMID: 33252464
Synopsis of Guidelines for the Clinical Management of Cerebral Cavernous Malformations: Consensus Recommendations Based on Systematic Literature Review by the Angioma Alliance Scientific Advisory Board Clinical Experts Panel.
Akers A, Al-Shahi Salman R, A Awad I, Dahlem K, Flemming K, Hart B, Kim H, Jusue-Torres I, Kondziolka D, Lee C, Morrison L, Rigamonti D, Rebeiz T, Tournier-Lasserve E, Waggoner D, Whitehead K
Neurosurgery 2017 May 1;80(5):665-680. doi: 10.1093/neuros/nyx091. PMID: 28387823Free PMC Article
Treatment of kaposiform hemangioendothelioma and tufted angioma.
Liu XH, Li JY, Qu XH, Yan WL, Zhang L, Yang C, Zheng JW
Int J Cancer 2016 Oct 1;139(7):1658-66. Epub 2016 Jun 28 doi: 10.1002/ijc.30216. PMID: 27252149
Visual outcome in Sturge-Weber syndrome: a systematic review and Dutch multicentre cohort.
Koenraads Y, van Egmond-Ebbeling MB, de Boer JH, Imhof SM, Braun KP, Porro GL; SWS study group
Acta Ophthalmol 2016 Nov;94(7):638-645. Epub 2016 May 30 doi: 10.1111/aos.13074. PMID: 27238857

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