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Wide femoral metaphysis

MedGen UID:
355309
•Concept ID:
C1864854
•
Finding
Synonym: Broad femoral metaphyses
 
HPO: HP:0006417

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVWide femoral metaphysis

Conditions with this feature

Camptodactyly-tall stature-scoliosis-hearing loss syndrome
MedGen UID:
355844
•Concept ID:
C1864852
•
Disease or Syndrome
This syndrome has characteristics of camptodactyly, tall stature, scoliosis, and hearing loss (CATSHL). It has been described in around 30 individuals from seven generations of the same family. The syndrome is caused by a missense mutation in the FGFR3 gene, leading to a partial loss of function of the encoded protein, which is a negative regulator of bone growth.
See: Condition Record
Camptodactyly-tall stature-scoliosis-hearing loss syndrome

Recent clinical studies

Etiology

Does the Clinical Presentation of Secondary Osteosarcoma in Patients Who Survive Retinoblastoma Differ From That of Conventional Osteosarcoma and How Do We Detect Them?
Kim Y, Park JW, Cho HS, Jang WY, Han I, Kim HS
Clin Orthop Relat Res 2023 Nov 1;481(11):2154-2163. Epub 2023 May 5 doi: 10.1097/CORR.0000000000002667. PMID: 37145140Free PMC Article
Vascularized Medial Femoral Condyle Bone Graft for Resistant Nonunion of the Distal Radius.
Henry M
J Hand Surg Asian Pac Vol 2017 Mar;22(1):23-28. doi: 10.1142/S0218810417500046. PMID: 28205468
The short stem: promises and pitfalls.
Stulberg SD, Patel RM
Bone Joint J 2013 Nov;95-B(11 Suppl A):57-62. doi: 10.1302/0301-620X.95B11.32936. PMID: 24187354
Stable, dependable fixation of short-stem femoral implants at 5 years.
Patel RM, Lo WM, Cayo MA, Dolan MM, Stulberg SD
Orthopedics 2013 Mar;36(3):e301-7. doi: 10.3928/01477447-20130222-18. PMID: 23464949
The periphysis and its effect on the metaphysis: I. Definition and normal radiographic pattern.
Oestreich AE, Ahmad BS
Skeletal Radiol 1992;21(5):283-6. doi: 10.1007/BF00241764. PMID: 1502578

Diagnosis

Does the Clinical Presentation of Secondary Osteosarcoma in Patients Who Survive Retinoblastoma Differ From That of Conventional Osteosarcoma and How Do We Detect Them?
Kim Y, Park JW, Cho HS, Jang WY, Han I, Kim HS
Clin Orthop Relat Res 2023 Nov 1;481(11):2154-2163. Epub 2023 May 5 doi: 10.1097/CORR.0000000000002667. PMID: 37145140Free PMC Article
Intramedullary Well-differentiated Osteosarcoma: Imaging and Pathologic Findings in 17 Patients.
Han SM, Wu Y, Wen JX, Wu TH, Sun T, Yu BH, Wu WJ, Gao BL
Curr Med Imaging 2022;18(14):1453-1461. doi: 10.2174/1573405618666211222160039. PMID: 34951370
What's New in Pediatric Hip?
Schmitz MR, Blumberg TJ, Nelson SE, Sees JP, Sankar WN
J Pediatr Orthop 2018 Jul;38(6):e300-e304. doi: 10.1097/BPO.0000000000001166. PMID: 29554020
Use of Massive Allografts to Manage Hydatid Bone Disease of the Femur.
Muscolo DL, Zaidenberg EE, Farfalli GL, Aponte-Tinao LA, Ayerza MA
Orthopedics 2015 Oct;38(10):e943-6. doi: 10.3928/01477447-20151002-92. PMID: 26488793
Primary alveolar soft part sarcoma of bone.
Park YK, Unni KK, Kim YW, Han CS, Yang MH, Wenger DE, Sim FH, Lucas DR, Ryan JR, Nadim YA, Nojima T, Fletcher CD
Histopathology 1999 Nov;35(5):411-7. doi: 10.1046/j.1365-2559.1999.035005411.x. PMID: 10583555

Therapy

Revision of total hip arthroplasty by long locking stem with fully hydroxyapatite-coated modular metaphysis (Reef™): A continuous series of 78 cases at a minimum 2-year follow-up.
de Leissegues T, Viste A, Fessy MH
Orthop Traumatol Surg Res 2024 Apr;110(2):103786. Epub 2023 Dec 7 doi: 10.1016/j.otsr.2023.103786. PMID: 38070731
Trans-Metaphyseal Screws Placed in Children: An Argument for Monitoring and Potentially Removing the Implants.
Gamble JG, Ziino C, Imrie MN, Young JL
J Pediatr Orthop 2019 Jan;39(1):e28-e31. doi: 10.1097/BPO.0000000000001280. PMID: 30379707
Parosteal osteosarcoma of the posterior aspect of the distal part of the femur. Oncological and functional results following a new resection technique.
Lewis VO, Gebhardt MC, Springfield DS
J Bone Joint Surg Am 2000 Aug;82(8):1083-8. doi: 10.2106/00004623-200008000-00003. PMID: 10954096
Distal loss of femoral bone following total knee arthroplasty. Measurement with visual and computer-processing of roentgenograms and dual-energy x-ray absorptiometry.
Robertson DD, Mintzer CM, Weissman BN, Ewald FC, LeBoff M, Spector M
J Bone Joint Surg Am 1994 Jan;76(1):66-76. doi: 10.2106/00004623-199401000-00009. PMID: 8288667

Prognosis

Revision of total hip arthroplasty by long locking stem with fully hydroxyapatite-coated modular metaphysis (Reef™): A continuous series of 78 cases at a minimum 2-year follow-up.
de Leissegues T, Viste A, Fessy MH
Orthop Traumatol Surg Res 2024 Apr;110(2):103786. Epub 2023 Dec 7 doi: 10.1016/j.otsr.2023.103786. PMID: 38070731
Intramedullary Well-differentiated Osteosarcoma: Imaging and Pathologic Findings in 17 Patients.
Han SM, Wu Y, Wen JX, Wu TH, Sun T, Yu BH, Wu WJ, Gao BL
Curr Med Imaging 2022;18(14):1453-1461. doi: 10.2174/1573405618666211222160039. PMID: 34951370
Total Hip Arthroplasty for Secondary Coxarthrosis in Patients with Hereditary Multiple Exostoses: Minimum 5-Year Follow-up Results and Surgical Considerations.
Yoon JY, Park CW, Park YS, Yoo JJ, Kim HJ
Clin Orthop Surg 2020 Dec;12(4):435-441. Epub 2020 Nov 18 doi: 10.4055/cios20044. PMID: 33274019Free PMC Article
The short stem: promises and pitfalls.
Stulberg SD, Patel RM
Bone Joint J 2013 Nov;95-B(11 Suppl A):57-62. doi: 10.1302/0301-620X.95B11.32936. PMID: 24187354
Diversity of proximal femoral medullary canal.
Laine HJ, Lehto MU, Moilanen T
J Arthroplasty 2000 Jan;15(1):86-92. doi: 10.1016/s0883-5403(00)91311-1. PMID: 10654468

Clinical prediction guides

Does the Clinical Presentation of Secondary Osteosarcoma in Patients Who Survive Retinoblastoma Differ From That of Conventional Osteosarcoma and How Do We Detect Them?
Kim Y, Park JW, Cho HS, Jang WY, Han I, Kim HS
Clin Orthop Relat Res 2023 Nov 1;481(11):2154-2163. Epub 2023 May 5 doi: 10.1097/CORR.0000000000002667. PMID: 37145140Free PMC Article
Novel WTX nonsense mutation in a family diagnosed with osteopathia striata with cranial sclerosis: Case report.
Jeong C, Kim M, Yim J, Park IJ, Lee J, Lee J
Medicine (Baltimore) 2021 Oct 8;100(40):e27346. doi: 10.1097/MD.0000000000027346. PMID: 34622833Free PMC Article
Total Hip Arthroplasty for Secondary Coxarthrosis in Patients with Hereditary Multiple Exostoses: Minimum 5-Year Follow-up Results and Surgical Considerations.
Yoon JY, Park CW, Park YS, Yoo JJ, Kim HJ
Clin Orthop Surg 2020 Dec;12(4):435-441. Epub 2020 Nov 18 doi: 10.4055/cios20044. PMID: 33274019Free PMC Article
Stable, dependable fixation of short-stem femoral implants at 5 years.
Patel RM, Lo WM, Cayo MA, Dolan MM, Stulberg SD
Orthopedics 2013 Mar;36(3):e301-7. doi: 10.3928/01477447-20130222-18. PMID: 23464949
Diversity of proximal femoral medullary canal.
Laine HJ, Lehto MU, Moilanen T
J Arthroplasty 2000 Jan;15(1):86-92. doi: 10.1016/s0883-5403(00)91311-1. PMID: 10654468

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