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Psoriasis 7, susceptibility to(PSORS7)

MedGen UID:
343057
•Concept ID:
C1854124
•
Finding
Synonyms: Psoriasis susceptibility 7; PSORS7
 
Gene (location): IL23R (1p31.3)
 
Monarch Initiative: MONDO:0011573
OMIM®: 605606

Professional guidelines

PubMed

A safety evaluation of guselkumab for the treatment of psoriasis.
Galluzzo M, D'Adamio S, Campione E, Bianchi L, Talamonti M
Expert Opin Drug Saf 2018 Jul;17(7):741-751. Epub 2018 Jul 4 doi: 10.1080/14740338.2018.1488963. PMID: 29897790
Genetics of susceptibility and treatment response in psoriatic arthritis.
O'Rielly DD, Rahman P
Nat Rev Rheumatol 2011 Nov 8;7(12):718-32. doi: 10.1038/nrrheum.2011.169. PMID: 22064628
HIV-associated psoriasis: pathogenesis, clinical features, and management.
Morar N, Willis-Owen SA, Maurer T, Bunker CB
Lancet Infect Dis 2010 Jul;10(7):470-8. doi: 10.1016/S1473-3099(10)70101-8. PMID: 20610329

Recent clinical studies

Etiology

Exposure to Air Pollution, Genetic Susceptibility, and Psoriasis Risk in the UK.
Wu J, Ma Y, Yang J, Tian Y
JAMA Netw Open 2024 Jul 1;7(7):e2421665. doi: 10.1001/jamanetworkopen.2024.21665. PMID: 39012635Free PMC Article
EULAR study group on 'MHC-I-opathy': identifying disease-overarching mechanisms across disciplines and borders.
Kuiper JJ, Prinz JC, Stratikos E, Kuśnierczyk P, Arakawa A, Springer S, Mintoff D, Padjen I, Shumnalieva R, Vural S, Kötter I, van de Sande MG, Boyvat A, de Boer JH, Bertsias G, de Vries N, Krieckaert CL, Leal I, Vidovič Valentinčič N, Tugal-Tutkun I, El Khaldi Ahanach H, Costantino F, Glatigny S, Mrazovac Zimak D, Lötscher F, Kerstens FG, Bakula M, Viera Sousa E, Böhm P, Bosman K, Kenna TJ, Powis SJ, Breban M, Gul A, Bowes J, Lories RJ, Nowatzky J, Wolbink GJ, McGonagle DG, Turkstra F; EULAR studygroup MHC-I-opathies
Ann Rheum Dis 2023 Jul;82(7):887-896. Epub 2023 Mar 27 doi: 10.1136/ard-2022-222852. PMID: 36987655Free PMC Article
Efficacy of guselkumab, a selective IL-23 inhibitor, in Preventing Arthritis in a Multicentre Psoriasis At-Risk cohort (PAMPA): protocol of a randomised, double-blind, placebo controlled multicentre trial.
Haberman RH, MacFarlane KA, Catron S, Samuels J, Blank RB, Toprover M, Uddin Z, Hu J, Castillo R, Gong C, Qian K, Piguet V, Tausk F, Yeung J, Neimann AL, Gulliver W, Thiele RG, Merola JF, Ogdie A, Rahman P, Chakravarty SD, Eder L, Ritchlin CT, Scher JU
BMJ Open 2022 Dec 23;12(12):e063650. doi: 10.1136/bmjopen-2022-063650. PMID: 36564123Free PMC Article
HLA-Cw1 and Psoriasis.
Huang YW, Tsai TF
Am J Clin Dermatol 2021 May;22(3):339-347. Epub 2021 Jan 18 doi: 10.1007/s40257-020-00585-1. PMID: 33460021Free PMC Article
Autoantibodies in inflammatory arthritis.
Conigliaro P, Chimenti MS, Triggianese P, Sunzini F, Novelli L, Perricone C, Perricone R
Autoimmun Rev 2016 Jul;15(7):673-83. Epub 2016 Mar 9 doi: 10.1016/j.autrev.2016.03.003. PMID: 26970491

Diagnosis

Plasma proteins and inflammatory dermatoses: proteome-wide Mendelian randomization and colocalization analyses.
Liu M, Chen M, Tan J, Chen A, Guo J
Arch Dermatol Res 2024 Jul 1;316(7):443. doi: 10.1007/s00403-024-03191-x. PMID: 38951247
A Mendelian randomization study of genetic predisposition to autoimmune diseases and COVID-19.
Li S, Yuan S, Schooling CM, Larsson SC
Sci Rep 2022 Oct 21;12(1):17703. doi: 10.1038/s41598-022-22711-1. PMID: 36271292Free PMC Article
HLA-Cw1 and Psoriasis.
Huang YW, Tsai TF
Am J Clin Dermatol 2021 May;22(3):339-347. Epub 2021 Jan 18 doi: 10.1007/s40257-020-00585-1. PMID: 33460021Free PMC Article
Autoantibodies in inflammatory arthritis.
Conigliaro P, Chimenti MS, Triggianese P, Sunzini F, Novelli L, Perricone C, Perricone R
Autoimmun Rev 2016 Jul;15(7):673-83. Epub 2016 Mar 9 doi: 10.1016/j.autrev.2016.03.003. PMID: 26970491
Pathogenetic overview of psoriatic disease.
Haroon M, Fitzgerald O
J Rheumatol Suppl 2012 Jul;89:7-10. doi: 10.3899/jrheum.120232. PMID: 22751581

Therapy

Exposure to Air Pollution, Genetic Susceptibility, and Psoriasis Risk in the UK.
Wu J, Ma Y, Yang J, Tian Y
JAMA Netw Open 2024 Jul 1;7(7):e2421665. doi: 10.1001/jamanetworkopen.2024.21665. PMID: 39012635Free PMC Article
Efficacy of guselkumab, a selective IL-23 inhibitor, in Preventing Arthritis in a Multicentre Psoriasis At-Risk cohort (PAMPA): protocol of a randomised, double-blind, placebo controlled multicentre trial.
Haberman RH, MacFarlane KA, Catron S, Samuels J, Blank RB, Toprover M, Uddin Z, Hu J, Castillo R, Gong C, Qian K, Piguet V, Tausk F, Yeung J, Neimann AL, Gulliver W, Thiele RG, Merola JF, Ogdie A, Rahman P, Chakravarty SD, Eder L, Ritchlin CT, Scher JU
BMJ Open 2022 Dec 23;12(12):e063650. doi: 10.1136/bmjopen-2022-063650. PMID: 36564123Free PMC Article
A Mendelian randomization study of genetic predisposition to autoimmune diseases and COVID-19.
Li S, Yuan S, Schooling CM, Larsson SC
Sci Rep 2022 Oct 21;12(1):17703. doi: 10.1038/s41598-022-22711-1. PMID: 36271292Free PMC Article
Pharmacogenomics for the efficacy and side effects of antihistamines.
Li L, Liu R, Peng C, Chen X, Li J
Exp Dermatol 2022 Jul;31(7):993-1004. Epub 2022 May 17 doi: 10.1111/exd.14602. PMID: 35538735
A safety evaluation of guselkumab for the treatment of psoriasis.
Galluzzo M, D'Adamio S, Campione E, Bianchi L, Talamonti M
Expert Opin Drug Saf 2018 Jul;17(7):741-751. Epub 2018 Jul 4 doi: 10.1080/14740338.2018.1488963. PMID: 29897790

Prognosis

Plasma proteins and psoriatic arthritis: a proteome-wide Mendelian randomization study.
Zhao H, Zhou Y, Wang Z, Zhang X, Chen L, Hong Z
Front Immunol 2024;15:1417564. Epub 2024 Jul 4 doi: 10.3389/fimmu.2024.1417564. PMID: 39026678Free PMC Article
Exposure to Air Pollution, Genetic Susceptibility, and Psoriasis Risk in the UK.
Wu J, Ma Y, Yang J, Tian Y
JAMA Netw Open 2024 Jul 1;7(7):e2421665. doi: 10.1001/jamanetworkopen.2024.21665. PMID: 39012635Free PMC Article
EULAR study group on 'MHC-I-opathy': identifying disease-overarching mechanisms across disciplines and borders.
Kuiper JJ, Prinz JC, Stratikos E, Kuśnierczyk P, Arakawa A, Springer S, Mintoff D, Padjen I, Shumnalieva R, Vural S, Kötter I, van de Sande MG, Boyvat A, de Boer JH, Bertsias G, de Vries N, Krieckaert CL, Leal I, Vidovič Valentinčič N, Tugal-Tutkun I, El Khaldi Ahanach H, Costantino F, Glatigny S, Mrazovac Zimak D, Lötscher F, Kerstens FG, Bakula M, Viera Sousa E, Böhm P, Bosman K, Kenna TJ, Powis SJ, Breban M, Gul A, Bowes J, Lories RJ, Nowatzky J, Wolbink GJ, McGonagle DG, Turkstra F; EULAR studygroup MHC-I-opathies
Ann Rheum Dis 2023 Jul;82(7):887-896. Epub 2023 Mar 27 doi: 10.1136/ard-2022-222852. PMID: 36987655Free PMC Article
Retinoid stability and degradation kinetics in commercial cosmetic products.
Temova Rakuša Ž, Škufca P, Kristl A, Roškar R
J Cosmet Dermatol 2021 Jul;20(7):2350-2358. Epub 2020 Dec 2 doi: 10.1111/jocd.13852. PMID: 33206444
Autoantibodies in inflammatory arthritis.
Conigliaro P, Chimenti MS, Triggianese P, Sunzini F, Novelli L, Perricone C, Perricone R
Autoimmun Rev 2016 Jul;15(7):673-83. Epub 2016 Mar 9 doi: 10.1016/j.autrev.2016.03.003. PMID: 26970491

Clinical prediction guides

Exposure to Air Pollution, Genetic Susceptibility, and Psoriasis Risk in the UK.
Wu J, Ma Y, Yang J, Tian Y
JAMA Netw Open 2024 Jul 1;7(7):e2421665. doi: 10.1001/jamanetworkopen.2024.21665. PMID: 39012635Free PMC Article
Dissecting causal relationships between primary biliary cholangitis and extrahepatic autoimmune diseases based on Mendelian randomization.
Ma G, Yang J, Wang X, Xia E, Yu J, Zhang M, Hu Y, Ma S, Zhou X, Fan Q, Han Y, Wang J
Sci Rep 2024 May 21;14(1):11528. doi: 10.1038/s41598-024-62509-x. PMID: 38773317Free PMC Article
Efficacy of guselkumab, a selective IL-23 inhibitor, in Preventing Arthritis in a Multicentre Psoriasis At-Risk cohort (PAMPA): protocol of a randomised, double-blind, placebo controlled multicentre trial.
Haberman RH, MacFarlane KA, Catron S, Samuels J, Blank RB, Toprover M, Uddin Z, Hu J, Castillo R, Gong C, Qian K, Piguet V, Tausk F, Yeung J, Neimann AL, Gulliver W, Thiele RG, Merola JF, Ogdie A, Rahman P, Chakravarty SD, Eder L, Ritchlin CT, Scher JU
BMJ Open 2022 Dec 23;12(12):e063650. doi: 10.1136/bmjopen-2022-063650. PMID: 36564123Free PMC Article
Retinoid stability and degradation kinetics in commercial cosmetic products.
Temova Rakuša Ž, Škufca P, Kristl A, Roškar R
J Cosmet Dermatol 2021 Jul;20(7):2350-2358. Epub 2020 Dec 2 doi: 10.1111/jocd.13852. PMID: 33206444
The coexistence of psoriasis and vitiligo: a review.
Sawchuk M, Spano F, Loo WJ, Guenther L
J Cutan Med Surg 2012 Sep-Oct;16(5):300-5. doi: 10.1177/120347541201600505. PMID: 22971303

Recent systematic reviews

Association between mutation of interleukin 36 receptor antagonist and generalized pustular psoriasis: A PRISMA-compliant systematic review and meta-analysis.
Liu ZJ, Tian YT, Shi BY, Zhou Y, Jia XS
Medicine (Baltimore) 2020 Nov 6;99(45):e23068. doi: 10.1097/MD.0000000000023068. PMID: 33157966Free PMC Article
The prevalence of culture-confirmed toenail onychomycosis in at-risk patient populations.
Gupta AK, Daigle D, Foley KA
J Eur Acad Dermatol Venereol 2015 Jun;29(6):1039-44. Epub 2014 Nov 21 doi: 10.1111/jdv.12873. PMID: 25413984
Meta-analysis of IL12B polymorphisms (rs3212227, rs6887695) with psoriasis and psoriatic arthritis.
Zhu KJ, Zhu CY, Shi G, Fan YM
Rheumatol Int 2013 Jul;33(7):1785-90. Epub 2013 Jan 8 doi: 10.1007/s00296-012-2637-4. PMID: 23297015

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