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Familial temporal lobe epilepsy

MedGen UID:
374964
Concept ID:
C1842564
Disease or Syndrome
Synonyms: Epilepsy, familial temporal lobe; Temporal epilepsy, familial
SNOMED CT: Familial temporal lobe epilepsy (783739005)
 
OMIM®: 608096

Definition

Rare genetic epilepsy with characteristics of mostly benign simple or complex partial seizures with autonomic or psychic auras. Seizures occur infrequently, are of short duration and are usually well controlled with medication. Development and cognition are normal. [from SNOMEDCT_US]

Recent clinical studies

Etiology

Ishida S, Picard F, Rudolf G, Noé E, Achaz G, Thomas P, Genton P, Mundwiller E, Wolff M, Marescaux C, Miles R, Baulac M, Hirsch E, Leguern E, Baulac S
Nat Genet 2013 May;45(5):552-5. Epub 2013 Mar 31 doi: 10.1038/ng.2601. PMID: 23542701Free PMC Article
Santos NF, Sousa SC, Kobayashi E, Torres FR, Sardinha JA, Cendes F, Lopes-Cendes I
Epilepsia 2002;43 Suppl 5:136. doi: 10.1046/j.1528-1157.43.s.5.23.x. PMID: 12121308
Ward N, Evanson J, Cockerell OC
Seizure 2002 Jan;11(1):16-9. doi: 10.1053/seiz.2001.0570. PMID: 11888255
Picard F, Baulac S, Kahane P, Hirsch E, Sebastianelli R, Thomas P, Vigevano F, Genton P, Guerrini R, Gericke CA, An I, Rudolf G, Herman A, Brice A, Marescaux C, LeGuern E
Brain 2000 Jun;123 ( Pt 6):1247-62. doi: 10.1093/brain/123.6.1247. PMID: 10825362
Cendes F, Lopes-Cendes I, Andermann E, Andermann F
Neurology 1998 Feb;50(2):554-7. doi: 10.1212/wnl.50.2.554. PMID: 9484399

Diagnosis

Zhang L, Jia Y, Wang Y
J Clin Neurosci 2020 Apr;74:268-270. Epub 2020 Feb 5 doi: 10.1016/j.jocn.2020.01.091. PMID: 32035795
Crompton DE, Scheffer IE, Taylor I, Cook MJ, McKelvie PA, Vears DF, Lawrence KM, McMahon JM, Grinton BE, McIntosh AM, Berkovic SF
Brain 2010 Nov;133(11):3221-31. Epub 2010 Sep 23 doi: 10.1093/brain/awq251. PMID: 20864493
Ward N, Evanson J, Cockerell OC
Seizure 2002 Jan;11(1):16-9. doi: 10.1053/seiz.2001.0570. PMID: 11888255
Berkovic SF, Scheffer IE
Brain Dev 1997 Jan;19(1):13-8. doi: 10.1016/s0387-7604(96)00060-5. PMID: 9071484
Berkovic SF, McIntosh A, Howell RA, Mitchell A, Sheffield LJ, Hopper JL
Ann Neurol 1996 Aug;40(2):227-35. doi: 10.1002/ana.410400214. PMID: 8773604

Therapy

Al-Asmi A, Jansen AC, Badhwar A, Dubeau F, Tampieri D, Shustik C, Mercho S, Savard G, Dobson-Stone C, Monaco AP, Andermann F, Andermann E
Epilepsia 2005 Aug;46(8):1256-63. doi: 10.1111/j.1528-1167.2005.65804.x. PMID: 16060937
Cendes F, Lopes-Cendes I, Andermann E, Andermann F
Neurology 1998 Feb;50(2):554-7. doi: 10.1212/wnl.50.2.554. PMID: 9484399

Prognosis

Eadie M
Seizure 2018 Jan;54:7-10. Epub 2017 Nov 14 doi: 10.1016/j.seizure.2017.11.010. PMID: 29172094
Striano P, Serioli E, Santulli L, Manna I, Labate A, Dazzo E, Pasini E, Gambardella A, Michelucci R, Striano S, Nobile C
Epilepsia 2015 Oct;56(10):e168-71. Epub 2015 Jul 27 doi: 10.1111/epi.13094. PMID: 26216793
Crompton DE, Scheffer IE, Taylor I, Cook MJ, McKelvie PA, Vears DF, Lawrence KM, McMahon JM, Grinton BE, McIntosh AM, Berkovic SF
Brain 2010 Nov;133(11):3221-31. Epub 2010 Sep 23 doi: 10.1093/brain/awq251. PMID: 20864493
Depondt C, Van Paesschen W, Matthijs G, Legius E, Martens K, Demaerel P, Wilms G
Neurology 2002 May 14;58(9):1429-33. doi: 10.1212/wnl.58.9.1429. PMID: 12011300
Ward N, Evanson J, Cockerell OC
Seizure 2002 Jan;11(1):16-9. doi: 10.1053/seiz.2001.0570. PMID: 11888255

Clinical prediction guides

Fabera P, Krijtova H, Tomasek M, Krysl D, Zamecnik J, Mohapl M, Jiruska P, Marusic P
Seizure 2015 Sep;31:120-3. Epub 2015 Jul 26 doi: 10.1016/j.seizure.2015.07.014. PMID: 26362388
Striano P, Serioli E, Santulli L, Manna I, Labate A, Dazzo E, Pasini E, Gambardella A, Michelucci R, Striano S, Nobile C
Epilepsia 2015 Oct;56(10):e168-71. Epub 2015 Jul 27 doi: 10.1111/epi.13094. PMID: 26216793
Chahine L, Abou-Khalil B, Siren A, Andermann F, Hedera P, Ge Q, Andermann E, Pandolfo M
Epilepsy Res 2013 Oct;106(3):338-44. Epub 2013 Aug 14 doi: 10.1016/j.eplepsyres.2013.07.007. PMID: 24021842
Crompton DE, Scheffer IE, Taylor I, Cook MJ, McKelvie PA, Vears DF, Lawrence KM, McMahon JM, Grinton BE, McIntosh AM, Berkovic SF
Brain 2010 Nov;133(11):3221-31. Epub 2010 Sep 23 doi: 10.1093/brain/awq251. PMID: 20864493
Santos NF, Sousa SC, Kobayashi E, Torres FR, Sardinha JA, Cendes F, Lopes-Cendes I
Epilepsia 2002;43 Suppl 5:136. doi: 10.1046/j.1528-1157.43.s.5.23.x. PMID: 12121308

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    Curated

    • NICE, 2022
      UK NICE Guideline NG217, Epilepsies in children, young people and adults, 2022

    Consumer resources

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