Warning: The NCBI web site requires JavaScript to function. more...

MedGen

National Center for Biotechnology Information

Full Report

Format

Full Report
Summary (Text)
Summary (XML)

Send to:

Choose Destination

File
Clipboard
Collections

CHEK2-Associated Li-Fraumeni-Like Syndrome

MedGen UID:: 322930
•Concept ID:: C1836482
•: Disease or Syndrome

Synonym:

Li-Fraumeni Syndrome 2

Definition

An autosomal dominant cancer predisposition syndrome caused by germline mutations of the CHEK2 gene. It is associated with breast carcinoma, gastric carcinoma, colorectal carcinoma, thyroid gland carcinoma, kidney carcinoma, prostate carcinoma, and non-Hodgkin lymphoma. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVCHEK2-Associated Li-Fraumeni-Like Syndrome

Disease with Cushing syndrome as a major feature
- Li-Fraumeni syndrome
  - CHEK2-Associated Li-Fraumeni-Like Syndrome

Supplemental Content

Table of contents

Related information

MeSH
Related Medical Subject Headings
PMC Articles
Related information in PubMed Central Links
PubMed
Related literature resources in PubMed

Recent activity

Clear Turn Off Turn On

CHEK2-Associated Li-Fraumeni-Like Syndrome
CHEK2-Associated Li-Fraumeni-Like Syndrome

MedGen
C1836482[conceptid] (1)
MedGen
Characidium longum[orgn] (0)
Genome
Staphylococcus
Staphylococcus

Genome
Genome Links for Taxonomy (Select 2989771) (1)
Genome

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...