Succedaneous Teeth, Agenesis Of

MedGen UID:: 331990
•Concept ID:: C1835493
•: Disease or Syndrome

Synonym:	SUCCEDANEOUS TEETH, AGENESIS OF

OMIM®:	150400

Recent clinical studies

Etiology

Canine substitution of congenitally missing maxillary lateral incisors in Class I and Class III malocclusions by using skeletal anchorage.

Amm EW, Antoszewska-Smith J, Boley J
Am J Orthod Dentofacial Orthop 2019 Oct;156(4):512-521.e6. doi: 10.1016/j.ajodo.2018.10.027. PMID: 31582123

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Therapy

The WNT10A gene in ectodermal dysplasias and selective tooth agenesis.

Mues G, Bonds J, Xiang L, Vieira AR, Seymen F, Klein O, D'Souza RN
Am J Med Genet A 2014 Oct;164A(10):2455-60. Epub 2014 Apr 3 doi: 10.1002/ajmg.a.36520. PMID: 24700731 Free PMC Article

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Clinical prediction guides

Identification of likely pathogenic and known variants in TSPEAR, LAMB3, BCOR, and WNT10A in four Turkish families with tooth agenesis.

Du R, Dinckan N, Song X, Coban-Akdemir Z, Jhangiani SN, Guven Y, Aktoren O, Kayserili H, Petty LE, Muzny DM, Below JE, Boerwinkle E, Wu N, Gibbs RA, Posey JE, Lupski JR, Letra A, Uyguner ZO
Hum Genet 2018 Sep;137(9):689-703. Epub 2018 Jul 26 doi: 10.1007/s00439-018-1907-y. PMID: 30046887 Free PMC Article

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Succedaneous Teeth, Agenesis Of

Recent clinical studies

Etiology

Therapy

Clinical prediction guides

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