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Complete luxation of lens

MedGen UID:
741477
•Concept ID:
C1827700
•
Anatomical Abnormality
Synonyms: Complete dislocation of lens; Displacement of lens; Luxation of lens
SNOMED CT: Complete luxation of lens (424416009); Luxation of lens (424416009); Complete dislocation of lens (424416009); Displacement of lens (424416009)

Professional guidelines

PubMed

Genetic testing results of children suspected to have Stickler syndrome type collagenopathy after ocular examination.
Khan AO, AlAbdi L, Patel N, Helaby R, Hashem M, Abdulwahab F, AlBadr FB, Alkuraya FS
Mol Genet Genomic Med 2021 May;9(5):e1628. Epub 2021 May 5 doi: 10.1002/mgg3.1628. PMID: 33951325Free PMC Article
Management of Severely Subluxated Cataracts Using Femtosecond Laser-Assisted Cataract Surgery.
Chee SP, Wong MH, Jap A
Am J Ophthalmol 2017 Jan;173:7-15. Epub 2016 Sep 23 doi: 10.1016/j.ajo.2016.09.021. PMID: 27670621
Glaucoma in microspherophakia: presenting features and treatment outcomes.
Senthil S, Rao HL, Hoang NT, Jonnadula GB, Addepalli UK, Mandal AK, Garudadari CS
J Glaucoma 2014 Apr-May;23(4):262-7. doi: 10.1097/IJG.0b013e3182707437. PMID: 23059485

Recent clinical studies

Etiology

Surgeries and Outcomes in Subluxated and Dislocated Lens in Eastern Nepal.
Shrestha P, Sharma S, Suwal R, Joshi P, Subedi P
Nepal J Ophthalmol 2023 Jul;15(30):8-16. doi: 10.3126/nepjoph.v15i2.56396. PMID: 38976332
Evaluation of functional vision and eye-related quality of life in children with congenital ectopia lentis: a prospective cross-sectional study.
Liang X, Zheng D, Young CA, Ma Y, Ling L, Zou M, Liu S, Zhang X, Jin G
BMJ Open 2023 Dec 21;13(12):e075222. doi: 10.1136/bmjopen-2023-075222. PMID: 38135313Free PMC Article
Effect of sutureless scleral fixed intraocular lens implantation on aphakic eyes: a system review and meta-analysis.
Liu Z, Xie Q, Chen X, Xie B, Cai S
BMC Ophthalmol 2023 Dec 6;23(1):493. doi: 10.1186/s12886-023-03223-6. PMID: 38053049Free PMC Article
Clinical profile and outcome of ocular manifestation in Marfans syndrome in India.
Shah S, Shah M, Chandane P, Makhloga S, Thorat D, Sanghani M
Indian J Ophthalmol 2022 Feb;70(2):626-629. doi: 10.4103/ijo.IJO_1651_21. PMID: 35086250Free PMC Article
Outcomes of trabeculectomy in microspherophakia.
Senthil S, Rao HL, Babu JG, Mandal AK, Addepalli UK, Garudadri CS
Indian J Ophthalmol 2014 May;62(5):601-5. doi: 10.4103/0301-4738.129785. PMID: 24881609Free PMC Article

Diagnosis

Zonule-Associated Gene Variants in Isolated Ectopia Lentis and Glaucoma.
Huang L, Xu T, Gan J, Mao Y, Zhao L, Jiao X, Fan M, Wang T, Zhang D, Xu M, Zhu Y, Hejtmancik JF, Liu X
J Glaucoma 2023 Jul 1;32(7):e80-e89. Epub 2023 Mar 20 doi: 10.1097/IJG.0000000000002209. PMID: 36946977
Clinical profile and outcome of ocular manifestation in Marfans syndrome in India.
Shah S, Shah M, Chandane P, Makhloga S, Thorat D, Sanghani M
Indian J Ophthalmol 2022 Feb;70(2):626-629. doi: 10.4103/ijo.IJO_1651_21. PMID: 35086250Free PMC Article
Ultrasound Biomicroscopy Diagnosis Analysis and Fine Care of Anterior Segment Injury of Traumatic Anterior Chamber Based on Intelligent Virtual Reality Technology.
Li X
J Healthc Eng 2021;2021:9930686. Epub 2021 May 11 doi: 10.1155/2021/9930686. PMID: 34055276Free PMC Article
Modified technique of endocapsular lens aspiration for severely subluxated lenses.
Khokhar S, Aron N, Yadav N, Pillay G, Agarwal E
Eye (Lond) 2018 Jan;32(1):128-135. Epub 2017 Aug 11 doi: 10.1038/eye.2017.160. PMID: 28799565Free PMC Article
Pathologic evidence of pseudoexfoliation in cases of in-the-bag intraocular lens subluxation or dislocation.
Liu E, Cole S, Werner L, Hengerer F, Mamalis N, Kohnen T
J Cataract Refract Surg 2015 May;41(5):929-35. Epub 2015 Apr 29 doi: 10.1016/j.jcrs.2014.08.037. PMID: 25935341

Therapy

Long-term surgical outcomes of primary retropupillary iris claw intraocular lens implantation for the treatment of intraocular lens dislocation.
Choi EY, Lee CH, Kang HG, Han JY, Byeon SH, Kim SS, Koh HJ, Kim M
Sci Rep 2021 Jan 12;11(1):726. doi: 10.1038/s41598-020-80292-3. PMID: 33436860Free PMC Article
Complications of femtosecond laser-assisted cataract surgery combined with vitrectomy.
Kubota M, Watanabe A, Watanabe T, Kono H, Hayashi T, Nakano T
Int Ophthalmol 2020 Apr;40(4):943-949. Epub 2020 Jan 8 doi: 10.1007/s10792-019-01266-7. PMID: 31916059
Modified technique of endocapsular lens aspiration for severely subluxated lenses.
Khokhar S, Aron N, Yadav N, Pillay G, Agarwal E
Eye (Lond) 2018 Jan;32(1):128-135. Epub 2017 Aug 11 doi: 10.1038/eye.2017.160. PMID: 28799565Free PMC Article
Scleral-fixated intraocular lens implantation in microspherophakia.
Subbiah S, Thomas PA, Jesudasan CA
Indian J Ophthalmol 2014 May;62(5):596-600. doi: 10.4103/0301-4738.129787. PMID: 24881608Free PMC Article
Glaucoma in microspherophakia: presenting features and treatment outcomes.
Senthil S, Rao HL, Hoang NT, Jonnadula GB, Addepalli UK, Mandal AK, Garudadari CS
J Glaucoma 2014 Apr-May;23(4):262-7. doi: 10.1097/IJG.0b013e3182707437. PMID: 23059485

Prognosis

Surgeries and Outcomes in Subluxated and Dislocated Lens in Eastern Nepal.
Shrestha P, Sharma S, Suwal R, Joshi P, Subedi P
Nepal J Ophthalmol 2023 Jul;15(30):8-16. doi: 10.3126/nepjoph.v15i2.56396. PMID: 38976332
Zonule-Associated Gene Variants in Isolated Ectopia Lentis and Glaucoma.
Huang L, Xu T, Gan J, Mao Y, Zhao L, Jiao X, Fan M, Wang T, Zhang D, Xu M, Zhu Y, Hejtmancik JF, Liu X
J Glaucoma 2023 Jul 1;32(7):e80-e89. Epub 2023 Mar 20 doi: 10.1097/IJG.0000000000002209. PMID: 36946977
Retinal break associated with traumatic lens dislocation or subluxation requiring vitrectomy.
Ke G, Zhou E, Zhu K, Wei Y, Wang Z, Jia Y, Wang S, Gu Y
Graefes Arch Clin Exp Ophthalmol 2020 Mar;258(3):693-697. Epub 2019 Nov 28 doi: 10.1007/s00417-019-04530-9. PMID: 31781882
Outcomes of trabeculectomy in microspherophakia.
Senthil S, Rao HL, Babu JG, Mandal AK, Addepalli UK, Garudadri CS
Indian J Ophthalmol 2014 May;62(5):601-5. doi: 10.4103/0301-4738.129785. PMID: 24881609Free PMC Article
Scleral-fixated intraocular lens implantation in microspherophakia.
Subbiah S, Thomas PA, Jesudasan CA
Indian J Ophthalmol 2014 May;62(5):596-600. doi: 10.4103/0301-4738.129787. PMID: 24881608Free PMC Article

Clinical prediction guides

Evaluation of functional vision and eye-related quality of life in children with congenital ectopia lentis: a prospective cross-sectional study.
Liang X, Zheng D, Young CA, Ma Y, Ling L, Zou M, Liu S, Zhang X, Jin G
BMJ Open 2023 Dec 21;13(12):e075222. doi: 10.1136/bmjopen-2023-075222. PMID: 38135313Free PMC Article
Zonule-Associated Gene Variants in Isolated Ectopia Lentis and Glaucoma.
Huang L, Xu T, Gan J, Mao Y, Zhao L, Jiao X, Fan M, Wang T, Zhang D, Xu M, Zhu Y, Hejtmancik JF, Liu X
J Glaucoma 2023 Jul 1;32(7):e80-e89. Epub 2023 Mar 20 doi: 10.1097/IJG.0000000000002209. PMID: 36946977
Retinal break associated with traumatic lens dislocation or subluxation requiring vitrectomy.
Ke G, Zhou E, Zhu K, Wei Y, Wang Z, Jia Y, Wang S, Gu Y
Graefes Arch Clin Exp Ophthalmol 2020 Mar;258(3):693-697. Epub 2019 Nov 28 doi: 10.1007/s00417-019-04530-9. PMID: 31781882
Pathologic evidence of pseudoexfoliation in cases of in-the-bag intraocular lens subluxation or dislocation.
Liu E, Cole S, Werner L, Hengerer F, Mamalis N, Kohnen T
J Cataract Refract Surg 2015 May;41(5):929-35. Epub 2015 Apr 29 doi: 10.1016/j.jcrs.2014.08.037. PMID: 25935341
The clinical spectrum of complete FBN1 allele deletions.
Hilhorst-Hofstee Y, Hamel BC, Verheij JB, Rijlaarsdam ME, Mancini GM, Cobben JM, Giroth C, Ruivenkamp CA, Hansson KB, Timmermans J, Moll HA, Breuning MH, Pals G
Eur J Hum Genet 2011 Mar;19(3):247-52. Epub 2010 Nov 10 doi: 10.1038/ejhg.2010.174. PMID: 21063442Free PMC Article

Recent systematic reviews

Effect of sutureless scleral fixed intraocular lens implantation on aphakic eyes: a system review and meta-analysis.
Liu Z, Xie Q, Chen X, Xie B, Cai S
BMC Ophthalmol 2023 Dec 6;23(1):493. doi: 10.1186/s12886-023-03223-6. PMID: 38053049Free PMC Article

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