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Low Grade Myofibroblastic Sarcoma

MedGen UID:
317844
Concept ID:
C1708751
Neoplastic Process
Synonyms: Low grade myofibroblastic sarcoma; Low-Grade Myofibroblastic Sarcoma; Myofibroblastic Sarcoma; Myofibrosarcoma
SNOMED CT: Low grade myofibroblastic sarcoma (703615007); Low grade myofibroblastic sarcoma (1290828003)

Definition

A low-grade malignant neoplasm arising from the soft tissue and rarely bone. It is characterized by the presence of spindle-shaped myofibroblasts and collagenous stroma formation in a storiform growth pattern. Metastasis is very rare. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLow Grade Myofibroblastic Sarcoma

Professional guidelines

PubMed

Xu Y, Xu G, Wang X, Mao M, Wu H, Baklaushev VP, Chekhonin VP, Peltzer K, Wang G, Zhang C
Clin Transl Oncol 2021 Feb;23(2):344-352. Epub 2020 Jun 30 doi: 10.1007/s12094-020-02425-4. PMID: 32607812

Recent clinical studies

Etiology

Haseli S, Mansoori B, Christensen D, Abadi A, Pooyan A, Shomal Zadeh F, Mau B, Khalili N, Murphey M, Chalian M
Radiographics 2023 Aug;43(8):e230005. doi: 10.1148/rg.230005. PMID: 37440448
Georgantzoglou N, Linos K
Semin Diagn Pathol 2023 Jul;40(4):295-305. Epub 2023 Apr 25 doi: 10.1053/j.semdp.2023.04.018. PMID: 37150655Free PMC Article
Baranov E, Hornick JL
Head Neck Pathol 2020 Mar;14(1):43-58. Epub 2020 Jan 16 doi: 10.1007/s12105-019-01104-3. PMID: 31950474Free PMC Article
Chan JY, Gooi Z, Wong EW, Ng SK, Tong MC, Vlantis AC
Laryngoscope 2017 Jan;127(1):116-121. Epub 2016 Jul 5 doi: 10.1002/lary.26146. PMID: 27377169
Sargar KM, Sheybani EF, Shenoy A, Aranake-Chrisinger J, Khanna G
Radiographics 2016 Jul-Aug;36(4):1195-214. doi: 10.1148/rg.2016150191. PMID: 27399243

Diagnosis

Giraldo-Roldan D, Louredo BVR, Penafort PVM, Pontes HAR, Alves AP, Lima FCA, Fonseca TC, Abrahão AC, Romañach MJ, Fonseca FP, Delgado WA, Robinson L, Van Heerden WFP, de Almeida OP, Vargas PA
Head Neck Pathol 2023 Sep;17(3):832-850. Epub 2023 Aug 4 doi: 10.1007/s12105-023-01577-3. PMID: 37540486Free PMC Article
Haseli S, Mansoori B, Christensen D, Abadi A, Pooyan A, Shomal Zadeh F, Mau B, Khalili N, Murphey M, Chalian M
Radiographics 2023 Aug;43(8):e230005. doi: 10.1148/rg.230005. PMID: 37440448
Georgantzoglou N, Linos K
Semin Diagn Pathol 2023 Jul;40(4):295-305. Epub 2023 Apr 25 doi: 10.1053/j.semdp.2023.04.018. PMID: 37150655Free PMC Article
Wang L, Li LX, Chen DQ, Yang L, Li SK, Cheng C
BMC Med Imaging 2019 May 2;19(1):36. doi: 10.1186/s12880-018-0287-z. PMID: 31046697Free PMC Article
Chan JY, Gooi Z, Wong EW, Ng SK, Tong MC, Vlantis AC
Laryngoscope 2017 Jan;127(1):116-121. Epub 2016 Jul 5 doi: 10.1002/lary.26146. PMID: 27377169

Therapy

Giraldo-Roldán D, Dos Santos GC, Araújo ALD, Nakamura TCR, Pulido-Díaz K, Lopes MA, Santos-Silva AR, Kowalski LP, Moraes MC, Vargas PA
Head Neck Pathol 2024 Oct 28;18(1):117. doi: 10.1007/s12105-024-01723-5. PMID: 39466448Free PMC Article
González-Cámpora R, Escudero AG, Ríos Martín JJ, Armas Padrón JR, Vázquez AH, Vázquez Ramírez FJ
Ultrastruct Pathol 2003 Jan-Feb;27(1):7-11. doi: 10.1080/01913120309942. PMID: 12554531

Prognosis

Haseli S, Mansoori B, Christensen D, Abadi A, Pooyan A, Shomal Zadeh F, Mau B, Khalili N, Murphey M, Chalian M
Radiographics 2023 Aug;43(8):e230005. doi: 10.1148/rg.230005. PMID: 37440448
Magro G, Salvatorelli L, Puzzo L, Piombino E, Bartoloni G, Broggi G, Vecchio GM
Pathologica 2019 Dec;111(4):344-360. doi: 10.32074/1591-951X-31-19. PMID: 31965112Free PMC Article
Zhang S, Ma Y, Ma T, Wang Z
Medicine (Baltimore) 2017 Dec;96(51):e9172. doi: 10.1097/MD.0000000000009172. PMID: 29390454Free PMC Article
Chan JY, Gooi Z, Wong EW, Ng SK, Tong MC, Vlantis AC
Laryngoscope 2017 Jan;127(1):116-121. Epub 2016 Jul 5 doi: 10.1002/lary.26146. PMID: 27377169
Sargar KM, Sheybani EF, Shenoy A, Aranake-Chrisinger J, Khanna G
Radiographics 2016 Jul-Aug;36(4):1195-214. doi: 10.1148/rg.2016150191. PMID: 27399243

Clinical prediction guides

Haseli S, Mansoori B, Christensen D, Abadi A, Pooyan A, Shomal Zadeh F, Mau B, Khalili N, Murphey M, Chalian M
Radiographics 2023 Aug;43(8):e230005. doi: 10.1148/rg.230005. PMID: 37440448
Gao G, Liu Y, Ao Y, Wang J, Xu Y
Medicine (Baltimore) 2022 Nov 11;101(45):e31715. doi: 10.1097/MD.0000000000031715. PMID: 36397412Free PMC Article
Wang L, Li LX, Chen DQ, Yang L, Li SK, Cheng C
BMC Med Imaging 2019 May 2;19(1):36. doi: 10.1186/s12880-018-0287-z. PMID: 31046697Free PMC Article
Zhang S, Ma Y, Ma T, Wang Z
Medicine (Baltimore) 2017 Dec;96(51):e9172. doi: 10.1097/MD.0000000000009172. PMID: 29390454Free PMC Article
Yamada T, Yoshimura T, Kitamura N, Sasabe E, Ohno S, Yamamoto T
Int J Oral Sci 2012 Sep;4(3):170-3. Epub 2012 Aug 31 doi: 10.1038/ijos.2012.49. PMID: 22935748Free PMC Article

Recent systematic reviews

Mamikunian G, Ziegler A, Block A, Thorpe E
Am J Clin Oncol 2023 Sep 1;46(9):420-425. Epub 2023 Jun 26 doi: 10.1097/COC.0000000000001025. PMID: 37358303

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