U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Lipidemia

MedGen UID:
317303
•Concept ID:
C1706412
•
Finding
Synonyms: Lipemia; Lipemias; Lipidemias

Definition

Abnormally high level of lipids in blood. [from MeSH]

Professional guidelines

PubMed

Antidiabetic treatment with gliptins: focus on cardiovascular effects and outcomes.
Fisman EZ, Tenenbaum A
Cardiovasc Diabetol 2015 Sep 29;14:129. doi: 10.1186/s12933-015-0294-0. PMID: 26415691Free PMC Article
Changes in lipidemia during chronic care treatment of childhood obesity.
Nielsen TR, Gamborg M, Fonvig CE, Kloppenborg J, Hvidt KN, Ibsen H, Holm JC
Child Obes 2012 Dec;8(6):533-41. doi: 10.1089/chi.2011.0098. PMID: 23181919
Pathophysiology and pharmacological treatment of insulin resistance.
Matthaei S, Stumvoll M, Kellerer M, Häring HU
Endocr Rev 2000 Dec;21(6):585-618. doi: 10.1210/edrv.21.6.0413. PMID: 11133066

Recent clinical studies

Etiology

GLP-1 receptor agonist-based therapies and cardiovascular risk: a review of mechanisms.
Mullur N, Morissette A, Morrow NM, Mulvihill EE
J Endocrinol 2024 Oct 1;263(1) Epub 2024 Sep 19 doi: 10.1530/JOE-24-0046. PMID: 39145614Free PMC Article
Galectin-3 Mediates Vascular Dysfunction in Obesity by Regulating NADPH Oxidase 1.
Padgett CA, Bátori RK, Speese AC, Rosewater CL, Bush WB, Derella CC, Haigh SB, Sellers HG, Corley ZL, West MA, Mintz JD, Ange BB, Harris RA, Brands MW, Fulton DJR, Stepp DW
Arterioscler Thromb Vasc Biol 2023 Oct;43(10):e381-e395. Epub 2023 Aug 10 doi: 10.1161/ATVBAHA.123.319476. PMID: 37586054Free PMC Article
Combined berberine and probiotic treatment as an effective regimen for improving postprandial hyperlipidemia in type 2 diabetes patients: a double blinded placebo controlled randomized study.
Wang S, Ren H, Zhong H, Zhao X, Li C, Ma J, Gu X, Xue Y, Huang S, Yang J, Chen L, Chen G, Qu S, Liang J, Qin L, Huang Q, Peng Y, Li Q, Wang X, Zou Y, Shi Z, Li X, Li T, Yang H, Lai S, Xu G, Li J, Zhang Y, Gu Y, Wang W
Gut Microbes 2022 Jan-Dec;14(1):2003176. doi: 10.1080/19490976.2021.2003176. PMID: 34923903Free PMC Article
Postprandial dysmetabolism and the heart.
Garber AJ
Heart Fail Clin 2012 Oct;8(4):563-73. Epub 2012 Aug 10 doi: 10.1016/j.hfc.2012.06.004. PMID: 22999240
Atherogenic nature of triglycerides, postprandial lipidemia, and triglyceride-rich remnant lipoproteins.
Zilversmit DB
Clin Chem 1995 Jan;41(1):153-8. PMID: 7813071

Diagnosis

Dyslipidemia Is Associated With Worse Asthma Clinical Outcomes: A Prospective Cohort Study.
Liu L, Liu Y, Zhang X, Yuan YL, Chen ZH, Chen-Yu Hsu A, Oliver BG, Xie M, Qin L, Li WM, Liu D, Wang G, Wood LG
J Allergy Clin Immunol Pract 2023 Mar;11(3):863-872.e8. Epub 2022 Dec 16 doi: 10.1016/j.jaip.2022.11.037. PMID: 36535523
Neurogenic stunned myocardium in acute ischemic stroke.
Ileri C, Dogan Z, Bulut B, Sunbul M, Sayar N, Midi I, Ozben B
Ideggyogy Sz 2022 Jan 30;75(1-02):15-22. doi: 10.18071/isz.75.0015. PMID: 35112517
Combined berberine and probiotic treatment as an effective regimen for improving postprandial hyperlipidemia in type 2 diabetes patients: a double blinded placebo controlled randomized study.
Wang S, Ren H, Zhong H, Zhao X, Li C, Ma J, Gu X, Xue Y, Huang S, Yang J, Chen L, Chen G, Qu S, Liang J, Qin L, Huang Q, Peng Y, Li Q, Wang X, Zou Y, Shi Z, Li X, Li T, Yang H, Lai S, Xu G, Li J, Zhang Y, Gu Y, Wang W
Gut Microbes 2022 Jan-Dec;14(1):2003176. doi: 10.1080/19490976.2021.2003176. PMID: 34923903Free PMC Article
Impact of multi-micronutrient supplementation on lipidemia of children and adolescents.
Chakrabarti A, Eiden M, Morin-Rivron D, Christinat N, Monteiro JP, Kaput J, Masoodi M
Clin Nutr 2020 Jul;39(7):2211-2219. Epub 2019 Oct 18 doi: 10.1016/j.clnu.2019.09.010. PMID: 31677804
Fibroblast growth factor-21, energy balance and obesity.
Giralt M, Gavaldà-Navarro A, Villarroya F
Mol Cell Endocrinol 2015 Dec 15;418 Pt 1:66-73. Epub 2015 Sep 26 doi: 10.1016/j.mce.2015.09.018. PMID: 26415590

Therapy

Healthy diet intervention reverses the progression of NASH through gut microbiota modulation.
Panyod S, Wu W-K, Hu M-Y, Huang H-S, Chen R-A, Chen Y-H, Shen T-CD, Ho C-T, Liu C-J, Chuang H-L, Huang C-C, Wu M-S, Sheen L-Y
Microbiol Spectr 2024 Jan 11;12(1):e0186823. Epub 2023 Nov 29 doi: 10.1128/spectrum.01868-23. PMID: 38018983Free PMC Article
Combined berberine and probiotic treatment as an effective regimen for improving postprandial hyperlipidemia in type 2 diabetes patients: a double blinded placebo controlled randomized study.
Wang S, Ren H, Zhong H, Zhao X, Li C, Ma J, Gu X, Xue Y, Huang S, Yang J, Chen L, Chen G, Qu S, Liang J, Qin L, Huang Q, Peng Y, Li Q, Wang X, Zou Y, Shi Z, Li X, Li T, Yang H, Lai S, Xu G, Li J, Zhang Y, Gu Y, Wang W
Gut Microbes 2022 Jan-Dec;14(1):2003176. doi: 10.1080/19490976.2021.2003176. PMID: 34923903Free PMC Article
Olive Leaf (Olea europaea L. folium): Potential Effects on Glycemia and Lipidemia.
Acar-Tek N, Ağagündüz D
Ann Nutr Metab 2020;76(1):10-15. Epub 2020 Jan 3 doi: 10.1159/000505508. PMID: 31901903
Postprandial dysmetabolism and the heart.
Garber AJ
Heart Fail Clin 2012 Oct;8(4):563-73. Epub 2012 Aug 10 doi: 10.1016/j.hfc.2012.06.004. PMID: 22999240
Atherogenic nature of triglycerides, postprandial lipidemia, and triglyceride-rich remnant lipoproteins.
Zilversmit DB
Clin Chem 1995 Jan;41(1):153-8. PMID: 7813071

Prognosis

Towards a consensus definition of allostatic load: a multi-cohort, multi-system, multi-biomarker individual participant data (IPD) meta-analysis.
McCrory C, McLoughlin S, Layte R, NiCheallaigh C, O'Halloran AM, Barros H, Berkman LF, Bochud M, M Crimmins E, T Farrell M, Fraga S, Grundy E, Kelly-Irving M, Petrovic D, Seeman T, Stringhini S, Vollenveider P, Kenny RA
Psychoneuroendocrinology 2023 Jul;153:106117. Epub 2023 Apr 19 doi: 10.1016/j.psyneuen.2023.106117. PMID: 37100008Free PMC Article
Neurogenic stunned myocardium in acute ischemic stroke.
Ileri C, Dogan Z, Bulut B, Sunbul M, Sayar N, Midi I, Ozben B
Ideggyogy Sz 2022 Jan 30;75(1-02):15-22. doi: 10.18071/isz.75.0015. PMID: 35112517
Moyamoya Disease and Syndrome: A National Inpatient Study of Ischemic Stroke Predictors.
Unda SR, Antoniazzi AM, Miller R, Klyde D, Javed K, Fluss R, Holland R, De la Garza Ramos R, Haranhalli N, Altschul DJ
J Stroke Cerebrovasc Dis 2021 Sep;30(9):105965. Epub 2021 Jul 8 doi: 10.1016/j.jstrokecerebrovasdis.2021.105965. PMID: 34247053
A meta-analysis of salicylates for type 2 diabetes mellitus.
Fang F, Lu Y, Ma DL, Du TT, Shao SY, Yu XF
J Huazhong Univ Sci Technolog Med Sci 2013 Feb;33(1):1-14. Epub 2013 Feb 8 doi: 10.1007/s11596-013-1063-5. PMID: 23392700
Physical activity and postprandial lipidemia: are energy expenditure and lipoprotein lipase activity the real modulators of the positive effect?
Peddie MC, Rehrer NJ, Perry TL
Prog Lipid Res 2012 Jan;51(1):11-22. Epub 2011 Nov 19 doi: 10.1016/j.plipres.2011.11.002. PMID: 22123195

Clinical prediction guides

GLP-1 receptor agonist-based therapies and cardiovascular risk: a review of mechanisms.
Mullur N, Morissette A, Morrow NM, Mulvihill EE
J Endocrinol 2024 Oct 1;263(1) Epub 2024 Sep 19 doi: 10.1530/JOE-24-0046. PMID: 39145614Free PMC Article
Towards a consensus definition of allostatic load: a multi-cohort, multi-system, multi-biomarker individual participant data (IPD) meta-analysis.
McCrory C, McLoughlin S, Layte R, NiCheallaigh C, O'Halloran AM, Barros H, Berkman LF, Bochud M, M Crimmins E, T Farrell M, Fraga S, Grundy E, Kelly-Irving M, Petrovic D, Seeman T, Stringhini S, Vollenveider P, Kenny RA
Psychoneuroendocrinology 2023 Jul;153:106117. Epub 2023 Apr 19 doi: 10.1016/j.psyneuen.2023.106117. PMID: 37100008Free PMC Article
Etiopathogenesis and Pharmacological Prevention of a Type-2 Diabetes Model in Male Mice.
Loizzo A, Spampinato SM, Campana G, Loizzo S
J Pharmacol Exp Ther 2018 Mar;364(2):347-358. Epub 2017 Nov 21 doi: 10.1124/jpet.117.244707. PMID: 29162628
Physical activity and postprandial lipidemia: are energy expenditure and lipoprotein lipase activity the real modulators of the positive effect?
Peddie MC, Rehrer NJ, Perry TL
Prog Lipid Res 2012 Jan;51(1):11-22. Epub 2011 Nov 19 doi: 10.1016/j.plipres.2011.11.002. PMID: 22123195
The potential of fenugreek (Trigonella foenum-graecum) as a functional food and nutraceutical and its effects on glycemia and lipidemia.
Roberts KT
J Med Food 2011 Dec;14(12):1485-9. Epub 2011 Aug 23 doi: 10.1089/jmf.2011.0002. PMID: 21861724

Recent systematic reviews

Effects of vitamin D supplementation on metabolic syndrome parameters in patients with obesity or diabetes in Brazil, Europe, and the United States: A systematic review and meta-analysis.
Oliveira INN, Macedo-Silva A, Coutinho-Cruz L, Sanchez-Almeida J, Tavares MPS, Majerowicz D
J Steroid Biochem Mol Biol 2024 Oct;243:106582. Epub 2024 Jul 9 doi: 10.1016/j.jsbmb.2024.106582. PMID: 38992391
A systematic review and meta-analysis of the effects of Hibiscus sabdariffa on blood pressure and cardiometabolic markers.
Ellis LR, Zulfiqar S, Holmes M, Marshall L, Dye L, Boesch C
Nutr Rev 2022 May 9;80(6):1723-1737. doi: 10.1093/nutrit/nuab104. PMID: 34927694Free PMC Article
Therapeutic efficacy of PCSK9 monoclonal antibodies in statin-nonresponsive patients with hypercholesterolemia and dyslipidemia: A systematic review and meta-analysis.
Peng W, Qiang F, Peng W, Qian Z, Ke Z, Yi L, Jian Z, Chongrong Q
Int J Cardiol 2016 Nov 1;222:119-129. Epub 2016 Jul 30 doi: 10.1016/j.ijcard.2016.07.239. PMID: 27494723
Whole-grain and blood lipid changes in apparently healthy adults: a systematic review and meta-analysis of randomized controlled studies.
Hollænder PL, Ross AB, Kristensen M
Am J Clin Nutr 2015 Sep;102(3):556-72. Epub 2015 Aug 12 doi: 10.3945/ajcn.115.109165. PMID: 26269373
A meta-analysis of salicylates for type 2 diabetes mellitus.
Fang F, Lu Y, Ma DL, Du TT, Shao SY, Yu XF
J Huazhong Univ Sci Technolog Med Sci 2013 Feb;33(1):1-14. Epub 2013 Feb 8 doi: 10.1007/s11596-013-1063-5. PMID: 23392700

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...