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Portal cirrhosis

MedGen UID:
351440
•Concept ID:
C1622502
•
Disease or Syndrome
Synonyms: Laennec's cirrhosis; PC - Portal cirrhosis; Portal Cirrhosis
SNOMED CT: Portal cirrhosis (419728003); Laennec's cirrhosis (419728003); PC - Portal cirrhosis (419728003)

Definition

A nutritional cirrhosis that is characterized by an increase in connective tissue surrounding the portal spaces. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPortal cirrhosis

Professional guidelines

PubMed

High risks adverse events associated with trastuzumab emtansine and trastuzumab deruxtecan for the treatment of HER2-positive/mutated malignancies: a pharmacovigilance study based on the FAERS database.
Ma P, Tian H, Shi Q, Liu R, Zhang Y, Qi X, Chen Y
Expert Opin Drug Saf 2023 Jul-Dec;22(8):685-696. Epub 2023 Apr 20 doi: 10.1080/14740338.2023.2204228. PMID: 37068935
Emerging role of statin therapy in the prevention and management of cirrhosis, portal hypertension, and HCC.
Sharpton SR, Loomba R
Hepatology 2023 Dec 1;78(6):1896-1906. Epub 2023 Jan 3 doi: 10.1097/HEP.0000000000000278. PMID: 37013380
Non-invasive diagnosis and follow-up of primary biliary cholangitis.
Corpechot C, Heurgue A, Tanne F, Potier P, Hanslik B, Decraecker M, de Lédinghen V, Ganne-Carrié N, Bureau C, Bourlière M
Clin Res Hepatol Gastroenterol 2022 Jan;46(1):101770. Epub 2021 Jul 28 doi: 10.1016/j.clinre.2021.101770. PMID: 34332135

Recent clinical studies

Etiology

RETROSPECTIVE ASSESSMENT OF CLINICAL-MORPHOLOGICAL CHANGES OF THE HEPATOBILIARY SYSTEM IN LIVER CIRRHOSIS OF THE CHORNOBYL NPP ACCIDENT CLEAN-UP WORKERS.
Sarkisova EO, Sushko VO, Chumak AA, Ovsyannikova LM, Nosach OV, Alyokhina SM, Shyiko TO
Probl Radiac Med Radiobiol 2019 Dec;24:465-479. doi: 10.33145/2304-8336-2019-24-465-479. PMID: 31841488
A non-linear mathematical model for the in vivo evaluation of the RES phagocytic function.
Bondareva IB, Parfenov AS
Medinfo 1995;8 Pt 2:1091. PMID: 8591376
Hepatocellular carcinoma in patients with acute intermittent porphyria.
Lithner F, Wetterberg L
Acta Med Scand 1984;215(3):271-4. doi: 10.1111/j.0954-6820.1984.tb05005.x. PMID: 6328897
Hepatic metastases and portal cirrhosis.
Goldstein MJ, Frable WJ, Sherlock P
Am J Med Sci 1966 Jul;252(1):26-30. doi: 10.1097/00000441-196607000-00004. PMID: 5941702
A note on the distribution of ABO blood groups in bronchiectasis and portal cirrhosis.
BILLINGTON BP
Australas Ann Med 1956 Feb;5(1):20-2. doi: 10.1111/imj.1956.5.1.20. PMID: 13315130

Diagnosis

Hyponatremia: manifestations and treatment.
Williams AV
J S C Med Assoc 1992 Jun;88(6):285-90. PMID: 1625451
THE DIAGNOSIS OF PORTAL CIRRHOSIS.
VAKIL BJ, SHAH SJ, TULPULE TH, DESAI MG
J Assoc Physicians India 1963 Oct;11:795-808. PMID: 14071777
Portal cirrhosis and postnecrotic liver scarring.
HICKEY M
Ir J Med Sci 1956 Jul;(367):289-300. PMID: 13345524
Portal cirrhosis; diagnosis and management.
KONAR NR
J Indian Med Assoc 1955 Mar 1;24(11):425-8. PMID: 14367839
The diagnosis and treatment of portal cirrhosis of the liver.
KIEFER ED
Surg Clin North Am 1948 Jun;28:713-20. doi: 10.1016/s0039-6109(16)32446-x. PMID: 18861530

Therapy

RETROSPECTIVE ASSESSMENT OF CLINICAL-MORPHOLOGICAL CHANGES OF THE HEPATOBILIARY SYSTEM IN LIVER CIRRHOSIS OF THE CHORNOBYL NPP ACCIDENT CLEAN-UP WORKERS.
Sarkisova EO, Sushko VO, Chumak AA, Ovsyannikova LM, Nosach OV, Alyokhina SM, Shyiko TO
Probl Radiac Med Radiobiol 2019 Dec;24:465-479. doi: 10.33145/2304-8336-2019-24-465-479. PMID: 31841488
Juvenile Wilson disease: histologic and functional studies during penicillamine therapy.
Grand RJ, Vawter GF
J Pediatr 1975 Dec;87(6 Pt 2):1161-70. doi: 10.1016/s0022-3476(75)80131-4. PMID: 1185415
Assessment of aminopyrine metabolism in man by breath analysis after oral administration of 14C-aminopyrine. Effects of phenobarbital, disulfiram and portal cirrhosis.
Hepner GW, Vesell ES
N Engl J Med 1974 Dec 26;291(26):1384-8. doi: 10.1056/NEJM197412262912605. PMID: 4427643
Cobalt excretion test for the assessment of body iron stores.
Sorbie J, Olatunbosun D, Corbett WE, Valberg LS
Can Med Assoc J 1971 May 8;104(9):777-82. PMID: 5578125Free PMC Article
Decompensated portal cirrhosis. Effects of large doses of phytonadione.
Ballard HS, Marcus AJ
Arch Intern Med 1966 Feb;117(2):182-6. doi: 10.1001/archinte.117.2.182. PMID: 5901549

Prognosis

RETROSPECTIVE ASSESSMENT OF CLINICAL-MORPHOLOGICAL CHANGES OF THE HEPATOBILIARY SYSTEM IN LIVER CIRRHOSIS OF THE CHORNOBYL NPP ACCIDENT CLEAN-UP WORKERS.
Sarkisova EO, Sushko VO, Chumak AA, Ovsyannikova LM, Nosach OV, Alyokhina SM, Shyiko TO
Probl Radiac Med Radiobiol 2019 Dec;24:465-479. doi: 10.33145/2304-8336-2019-24-465-479. PMID: 31841488
Juvenile Wilson disease: histologic and functional studies during penicillamine therapy.
Grand RJ, Vawter GF
J Pediatr 1975 Dec;87(6 Pt 2):1161-70. doi: 10.1016/s0022-3476(75)80131-4. PMID: 1185415
ONE THOUSAND CASES OF PORTAL CIRRHOSIS OF THE LIVER. IMPLICATIONS OF ESOPHAGEAL VARICES AND THEIR MANAGEMENT.
BRICK IB, PALMER ED
Arch Intern Med 1964 Apr;113:501-11. doi: 10.1001/archinte.1964.00280100009003. PMID: 14109008
The low incidence of myocardial infarction in patients with portal cirrhosis of the liver: A review of 639 cases of cirrhosis of the liver from 17,731 autopsies.
HOWELL WL, MANION WC
Am Heart J 1960 Sep;60:341-4. doi: 10.1016/0002-8703(60)90192-7. PMID: 14403495
The incidence of portal cirrhosis and fatty metamorphosis in patients dying with diabetes mellitus.
JAQUES WE
N Engl J Med 1953 Sep 10;249(11):442-5. doi: 10.1056/NEJM195309102491104. PMID: 13087619

Clinical prediction guides

Juvenile Wilson disease: histologic and functional studies during penicillamine therapy.
Grand RJ, Vawter GF
J Pediatr 1975 Dec;87(6 Pt 2):1161-70. doi: 10.1016/s0022-3476(75)80131-4. PMID: 1185415
Hepatic lesions in pancreatitis. Clinicoexperimental data.
Tuzhilin SA, Podolsky AE, Dreiling DA
Am J Gastroenterol 1975 Aug;64(2):108-14. PMID: 1181913
Observations on portal cirrhosis of the liver; with special reference to the diagnosis of early and late cases.
KONAR NR
J Indian Med Assoc 1957 May 1;28(9):377-80. PMID: 13439180
Clinical observations on the severity of liver failure in portal cirrhosis.
RICKETTS WE, KIRSNER JB, PALMER WL
Gastroenterology 1950 Jun;15(2):245-56. PMID: 15427770
Hepatitis and its sequelae, including the development of portal cirrhosis; observations on 100 cases.
KOSZALKA MF, LINDERT MC
Arch Intern Med (Chic) 1949 Nov;84(5):782-97. doi: 10.1001/archinte.1949.00230050118006. PMID: 15406857

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