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Lentiglobus

MedGen UID:
488978
•Concept ID:
C1622439
•
Congenital Abnormality
Synonym: Bulging of eye lens
SNOMED CT: Lentiglobus (419281007)
 
HPO: HP:0011527

Definition

Exaggerated curvature of the lens of the eye, producing an anterior or posterior spherical bulging. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLentiglobus

Professional guidelines

PubMed

Preoperative considerations and outcomes of primary intraocular lens implantation in children with posterior polar and posterior lentiglobus cataract.
Mistr SK, Trivedi RH, Wilson ME
J AAPOS 2008 Feb;12(1):58-61. Epub 2007 Oct 29 doi: 10.1016/j.jaapos.2007.08.003. PMID: 18029213

Recent clinical studies

Etiology

A Novel Congenital Cataract Category System Based on Lens Opacity Locations and Relevant Anterior Segment Characteristics.
Lin H, Lin D, Liu Z, Long E, Wu X, Cao Q, Chen J, Lin Z, Li X, Zhang L, Chen H, Zhang X, Li J, Chen W, Liu Y
Invest Ophthalmol Vis Sci 2016 Nov 1;57(14):6389-6395. doi: 10.1167/iovs.16-20280. PMID: 27898985
Preoperative considerations and outcomes of primary intraocular lens implantation in children with posterior polar and posterior lentiglobus cataract.
Mistr SK, Trivedi RH, Wilson ME
J AAPOS 2008 Feb;12(1):58-61. Epub 2007 Oct 29 doi: 10.1016/j.jaapos.2007.08.003. PMID: 18029213
Coloboma of the crystalline lens.
Ilsen PF, Patel S
Optometry 2003 Dec;74(12):765-74. PMID: 14677728
Long-term visual results and complications in children with aphakia. A function of cataract type.
Parks MM, Johnson DA, Reed GW
Ophthalmology 1993 Jun;100(6):826-40; discussion 840-1. doi: 10.1016/s0161-6420(93)31566-6. PMID: 8510894

Diagnosis

Bilateral Cataracts and Posterior Lentiglobus in USP9X Syndrome.
Hwang ES, Harrie RP, Desautels J
Ophthalmology 2024 Oct;131(10):1245. Epub 2023 Dec 15 doi: 10.1016/j.ophtha.2023.10.023. PMID: 38099911
A Novel Congenital Cataract Category System Based on Lens Opacity Locations and Relevant Anterior Segment Characteristics.
Lin H, Lin D, Liu Z, Long E, Wu X, Cao Q, Chen J, Lin Z, Li X, Zhang L, Chen H, Zhang X, Li J, Chen W, Liu Y
Invest Ophthalmol Vis Sci 2016 Nov 1;57(14):6389-6395. doi: 10.1167/iovs.16-20280. PMID: 27898985
Intraoperative posterior capsule flutter in posterior lentiglobus.
Praveen MR, Vasavada AR, Koul A, Ravat FA, Trivedi RH, Shah SK, Vasavada VA
J AAPOS 2010 Aug;14(4):367-8. Epub 2010 Jul 3 doi: 10.1016/j.jaapos.2010.02.008. PMID: 20598928
Intraocular lens implantation in pediatric eyes with posterior lentiglobus.
Wilson ME, Trivedi RH
Trans Am Ophthalmol Soc 2006;104:176-82. PMID: 17471338Free PMC Article
Coloboma of the crystalline lens.
Ilsen PF, Patel S
Optometry 2003 Dec;74(12):765-74. PMID: 14677728

Prognosis

Intraoperative posterior capsule flutter in posterior lentiglobus.
Praveen MR, Vasavada AR, Koul A, Ravat FA, Trivedi RH, Shah SK, Vasavada VA
J AAPOS 2010 Aug;14(4):367-8. Epub 2010 Jul 3 doi: 10.1016/j.jaapos.2010.02.008. PMID: 20598928
Preoperative considerations and outcomes of primary intraocular lens implantation in children with posterior polar and posterior lentiglobus cataract.
Mistr SK, Trivedi RH, Wilson ME
J AAPOS 2008 Feb;12(1):58-61. Epub 2007 Oct 29 doi: 10.1016/j.jaapos.2007.08.003. PMID: 18029213
Long-term visual results and complications in children with aphakia. A function of cataract type.
Parks MM, Johnson DA, Reed GW
Ophthalmology 1993 Jun;100(6):826-40; discussion 840-1. doi: 10.1016/s0161-6420(93)31566-6. PMID: 8510894

Clinical prediction guides

Intraocular lens implantation in pediatric eyes with posterior lentiglobus.
Wilson ME, Trivedi RH
Trans Am Ophthalmol Soc 2006;104:176-82. PMID: 17471338Free PMC Article
Long-term visual results and complications in children with aphakia. A function of cataract type.
Parks MM, Johnson DA, Reed GW
Ophthalmology 1993 Jun;100(6):826-40; discussion 840-1. doi: 10.1016/s0161-6420(93)31566-6. PMID: 8510894

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