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Atherogenesis

MedGen UID:
327644
•Concept ID:
C1563937
•
Pathologic Function
Synonym: Atherogeneses

Professional guidelines

PubMed

Nanomedicine for Diagnosis and Treatment of Atherosclerosis.
Cheng J, Huang H, Chen Y, Wu R
Adv Sci (Weinh) 2023 Dec;10(36):e2304294. Epub 2023 Oct 28 doi: 10.1002/advs.202304294. PMID: 37897322Free PMC Article
Exogenous NO Therapy for the Treatment and Prevention of Atherosclerosis.
Gori T
Int J Mol Sci 2020 Apr 13;21(8) doi: 10.3390/ijms21082703. PMID: 32295055Free PMC Article
Treatment of hyperlipidemia.
Kane JP, Malloy MJ
Annu Rev Med 1990;41:471-82. doi: 10.1146/annurev.me.41.020190.002351. PMID: 2184745

Recent clinical studies

Etiology

LncRNA DANCR promotes macrophage lipid accumulation through modulation of membrane cholesterol transporters.
Zhao GJ, Wang Y, An JH, Tang WY, Xu XD, Ren K
Aging (Albany NY) 2024 Jul 2;16(18):12510-12524. doi: 10.18632/aging.205992. PMID: 38968577Free PMC Article

Therapy

LP(a): Structure, Genetics, Associated Cardiovascular Risk, and Emerging Therapeutics.
Tasdighi E, Adhikari R, Almaadawy O, Leucker TM, Blaha MJ
Annu Rev Pharmacol Toxicol 2024 Jan 23;64:135-157. Epub 2023 Jul 28 doi: 10.1146/annurev-pharmtox-031023-100609. PMID: 37506332
Sclerostin and Cardiovascular Disease.
Tobias JH
Curr Osteoporos Rep 2023 Oct;21(5):519-526. Epub 2023 Jul 25 doi: 10.1007/s11914-023-00810-w. PMID: 37490188Free PMC Article
When to lower triglycerides?
Ganda OP
Curr Opin Lipidol 2020 Aug;31(4):238-245. doi: 10.1097/MOL.0000000000000694. PMID: 32520780
Apolipoprotein B Particles and Cardiovascular Disease: A Narrative Review.
Sniderman AD, Thanassoulis G, Glavinovic T, Navar AM, Pencina M, Catapano A, Ference BA
JAMA Cardiol 2019 Dec 1;4(12):1287-1295. doi: 10.1001/jamacardio.2019.3780. PMID: 31642874Free PMC Article
Atherosclerosis and inflammation: overview and updates.
Geovanini GR, Libby P
Clin Sci (Lond) 2018 Jun 29;132(12):1243-1252. Epub 2018 Jun 21 doi: 10.1042/CS20180306. PMID: 29930142

Prognosis

Hegemony of inflammation in atherosclerosis and coronary artery disease.
Attiq A, Afzal S, Ahmad W, Kandeel M
Eur J Pharmacol 2024 Mar 5;966:176338. Epub 2024 Jan 17 doi: 10.1016/j.ejphar.2024.176338. PMID: 38242225
Telomere Length: Implications for Atherogenesis.
Yin H, Pickering JG
Curr Atheroscler Rep 2023 Mar;25(3):95-103. Epub 2023 Jan 23 doi: 10.1007/s11883-023-01082-6. PMID: 36689071Free PMC Article
Triglyceride-Rich Lipoprotein Cholesterol, Small Dense LDL Cholesterol, and Incident Cardiovascular Disease.
Duran EK, Aday AW, Cook NR, Buring JE, Ridker PM, Pradhan AD
J Am Coll Cardiol 2020 May 5;75(17):2122-2135. doi: 10.1016/j.jacc.2020.02.059. PMID: 32354380Free PMC Article
Hypoxia in Atherogenesis.
Ferns GAA, Heikal L
Angiology 2017 Jul;68(6):472-493. Epub 2016 Aug 27 doi: 10.1177/0003319716662423. PMID: 27568384
Inflammation and atherosclerosis.
Libby P, Ridker PM, Maseri A
Circulation 2002 Mar 5;105(9):1135-43. doi: 10.1161/hc0902.104353. PMID: 11877368

Clinical prediction guides

Blood Monocyte Phenotype Is A Marker of Cardiovascular Risk in Type 2 Diabetes.
Julla JB, Girard D, Diedisheim M, Saulnier PJ, Tran Vuong B, Blériot C, Carcarino E, De Keizer J, Orliaguet L, Nemazanyy I, Potier C, Khider K, Tonui DC, Ejlalmanesh T, Ballaire R, Mambu Mambueni H, Germain S, Gaborit B, Vidal-Trécan T, Riveline JP, Garchon HJ, Fenaille F, Lemoine S, Carlier A, Castelli F, Potier L, Masson D, Roussel R, Vandiedonck C, Hadjadj S, Alzaid F, Gautier JF, Venteclef N
Circ Res 2024 Jan 19;134(2):189-202. Epub 2023 Dec 28 doi: 10.1161/CIRCRESAHA.123.322757. PMID: 38152893
Exosome-derived circ_0001785 delays atherogenesis through the ceRNA network mechanism of miR-513a-5p/TGFBR3.
Tong X, Dang X, Liu D, Wang N, Li M, Han J, Zhao J, Wang Y, Huang M, Yang Y, Yang Y, Wang W, Kou Y, Kou J
J Nanobiotechnology 2023 Oct 4;21(1):362. doi: 10.1186/s12951-023-02076-x. PMID: 37794449Free PMC Article
Cationic proteins from eosinophils bind bone morphogenetic protein receptors promoting vascular calcification and atherogenesis.
Meng Z, Zhang S, Li W, Wang Y, Wang M, Liu X, Liu CL, Liao S, Liu T, Yang C, Lindholt JS, Rasmussen LM, Obel LM, Stubbe J, Diederichsen AC, Sun Y, Chen Y, Yu PB, Libby P, Shi GP, Guo J
Eur Heart J 2023 Aug 1;44(29):2763-2783. doi: 10.1093/eurheartj/ehad262. PMID: 37279475Free PMC Article
Telomere Length: Implications for Atherogenesis.
Yin H, Pickering JG
Curr Atheroscler Rep 2023 Mar;25(3):95-103. Epub 2023 Jan 23 doi: 10.1007/s11883-023-01082-6. PMID: 36689071Free PMC Article
Mechanisms and therapy of atherosclerosis and its clinical complications.
Barton M
Curr Opin Pharmacol 2013 Apr;13(2):149-53. Epub 2013 May 28 doi: 10.1016/j.coph.2013.05.001. PMID: 23721738

Recent systematic reviews

Recent advances and controversial issues in the optimal management of asymptomatic carotid stenosis.
Paraskevas KI, Brown MM, Lal BK, Myrcha P, Lyden SP, Schneider PA, Poredos P, Mikhailidis DP, Secemsky EA, Musialek P, Mansilha A, Parikh SA, Silvestrini M, Lavie CJ, Dardik A, Blecha M, Liapis CD, Zeebregts CJ, Nederkoorn PJ, Poredos P, Gurevich V, Jawien A, Lanza G, Gray WA, Gupta A, Svetlikov AV, Fernandes E Fernandes J, Nicolaides AN, White CJ, Meschia JF, Cronenwett JL, Schermerhorn ML, AbuRahma AF
J Vasc Surg 2024 Mar;79(3):695-703. Epub 2023 Nov 7 doi: 10.1016/j.jvs.2023.11.004. PMID: 37939746
Role of Blood-Based Biomarkers in Ischemic Stroke Prognosis: A Systematic Review.
Montellano FA, Ungethüm K, Ramiro L, Nacu A, Hellwig S, Fluri F, Whiteley WN, Bustamante A, Montaner J, Heuschmann PU
Stroke 2021 Jan;52(2):543-551. Epub 2021 Jan 12 doi: 10.1161/STROKEAHA.120.029232. PMID: 33430636
Association Between Obesity and Cardiovascular Outcomes: A Systematic Review and Meta-analysis of Mendelian Randomization Studies.
Riaz H, Khan MS, Siddiqi TJ, Usman MS, Shah N, Goyal A, Khan SS, Mookadam F, Krasuski RA, Ahmed H
JAMA Netw Open 2018 Nov 2;1(7):e183788. doi: 10.1001/jamanetworkopen.2018.3788. PMID: 30646365Free PMC Article
Hepatitis C and Its Metabolic Complications in Kidney Disease.
Fabrizi F, Donato FM, Messa P
Ann Hepatol 2017 November-December,;16(6):851-861. doi: 10.5604/01.3001.0010.5275. PMID: 29055921
A role for autoantibodies in atherogenesis.
Iseme RA, McEvoy M, Kelly B, Agnew L, Walker FR, Handley T, Oldmeadow C, Attia J, Boyle M
Cardiovasc Res 2017 Aug 1;113(10):1102-1112. doi: 10.1093/cvr/cvx112. PMID: 28899001

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