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Human herpesvirus 8 infection

MedGen UID:
268211
•Concept ID:
C1512508
•
Disease or Syndrome
Synonyms: HHV8 Infection; HHV8 infection; Human Herpes Virus 8 infection; Human Herpesvirus 8 Infection; human herpesvirus 8 infection; Human Herpesvirus 8 infection
 
Monarch Initiative: MONDO:0005187

Definition

An infectious process caused by the human herpesvirus 8. This infection is associated with Kaposi sarcoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHuman herpesvirus 8 infection

Professional guidelines

PubMed

Iron: a target for the management of Kaposi's sarcoma?
Simonart T
BMC Cancer 2004 Jan 15;4:1. doi: 10.1186/1471-2407-4-1. PMID: 14725718Free PMC Article
Guidelines for preventing opportunistic infections among HIV-infected persons--2002. Recommendations of the U.S. Public Health Service and the Infectious Diseases Society of America.
Masur H, Kaplan JE, Holmes KK; U.S. Public Health Service; Infectious Diseases Society of America
Ann Intern Med 2002 Sep 3;137(5 Pt 2):435-78. doi: 10.7326/0003-4819-137-5_part_2-200209031-00002. PMID: 12617574
Guidelines for preventing opportunistic infections among HIV-infected persons--2002. Recommendations of the U.S. Public Health Service and the Infectious Diseases Society of America.
Kaplan JE, Masur H, Holmes KK; USPHS; Infectious Disease Society of America
MMWR Recomm Rep 2002 Jun 14;51(RR-8):1-52. PMID: 12081007

Recent clinical studies

Etiology

Human herpesvirus-8 infection in Tunisian adult acute leukemia patients.
Handous I, Hannachi N, Achour B, Marzouk M, Hazgui O, Yacoub S, Khelif A, Boukadida J
Afr Health Sci 2023 Mar;23(1):504-510. doi: 10.4314/ahs.v23i1.52. PMID: 37545962Free PMC Article
Human herpesvirus 8 infection is associated with prostate cancer among IFNL4-ΔG carriers.
Jenkins FJ, Minas TZ, Tang W, Dorsey TH, Ambs S
Prostate Cancer Prostatic Dis 2023 Jun;26(2):338-346. Epub 2022 Apr 25 doi: 10.1038/s41391-022-00546-1. PMID: 35468990Free PMC Article
Seroepidemiology of the human herpesvirus 8 infection among people living with HIV in Taiwan, 2014-2018.
Tsai MJ, Sun HY, Hsieh SM, Sheng WH, Chuang YC, Huang YS, Huang SH, Su LH, Su YC, Liu WC, Chang SY, Hung CC
J Microbiol Immunol Infect 2021 Oct;54(5):934-943. Epub 2020 Dec 9 doi: 10.1016/j.jmii.2020.11.005. PMID: 33349600
Is human herpesvirus 8 infection more common in men than in women? Systematic review and meta-analysis.
Begré L, Rohner E, Mbulaiteye SM, Egger M, Bohlius J
Int J Cancer 2016 Aug 15;139(4):776-83. Epub 2016 Apr 26 doi: 10.1002/ijc.30129. PMID: 27062038Free PMC Article
Transmission of human herpesvirus 8: an update.
Pica F, Volpi A
Curr Opin Infect Dis 2007 Apr;20(2):152-6. doi: 10.1097/QCO.0b013e3280143919. PMID: 17496573

Diagnosis

Lymphoproliferative Disorders of the Lung.
Borie R, Wislez M, Antoine M, Cadranel J
Respiration 2017;94(2):157-175. Epub 2017 Jun 14 doi: 10.1159/000477740. PMID: 28609772
Primary effusion lymphoma.
Patel S, Xiao P
Arch Pathol Lab Med 2013 Aug;137(8):1152-4. doi: 10.5858/arpa.2012-0294-RS. PMID: 23899073
Transmission of human herpesvirus 8: an update.
Pica F, Volpi A
Curr Opin Infect Dis 2007 Apr;20(2):152-6. doi: 10.1097/QCO.0b013e3280143919. PMID: 17496573
Diagnosis and epidemiology of human herpesvirus 8 infection.
Martin JN
Semin Hematol 2003 Apr;40(2):133-42. doi: 10.1053/shem.2003.50013. PMID: 12704590
Human herpesvirus 8 infection.
Jenson HB
Curr Opin Pediatr 2003 Feb;15(1):85-91. doi: 10.1097/00008480-200302000-00014. PMID: 12544277

Therapy

Hemophagocytic lymphohistiocytosis occurring after liver transplantation: A case series and review of the literature.
Chesner J, Schiano TD, Fiel MI, Crismale JF
Clin Transplant 2021 Aug;35(8):e14392. Epub 2021 Jul 8 doi: 10.1111/ctr.14392. PMID: 34159642
Is human herpesvirus 8 infection more common in men than in women? Systematic review and meta-analysis.
Begré L, Rohner E, Mbulaiteye SM, Egger M, Bohlius J
Int J Cancer 2016 Aug 15;139(4):776-83. Epub 2016 Apr 26 doi: 10.1002/ijc.30129. PMID: 27062038Free PMC Article
Oral HIV-associated Kaposi sarcoma.
Pantanowitz L, Khammissa RA, Lemmer J, Feller L
J Oral Pathol Med 2013 Mar;42(3):201-7. Epub 2012 Jun 5 doi: 10.1111/j.1600-0714.2012.01180.x. PMID: 22672182
The role of human herpesvirus 8 in the pathogenesis of Kaposi's sarcoma.
Blauvelt A
Adv Dermatol 1999;14:167-206; discussion 207. PMID: 10643499
Transmission of human herpesvirus 8 infection from renal-transplant donors to recipients.
Regamey N, Tamm M, Wernli M, Witschi A, Thiel G, Cathomas G, Erb P
N Engl J Med 1998 Nov 5;339(19):1358-63. doi: 10.1056/NEJM199811053391903. PMID: 9801396

Prognosis

Is human herpesvirus 8 infection more common in men than in women? an updated meta-analysis.
Gong H, Zhang S, Dou J, Chen J
BMC Infect Dis 2024 Apr 29;24(1):454. doi: 10.1186/s12879-024-09346-5. PMID: 38684967Free PMC Article
Seroepidemiology of the human herpesvirus 8 infection among people living with HIV in Taiwan, 2014-2018.
Tsai MJ, Sun HY, Hsieh SM, Sheng WH, Chuang YC, Huang YS, Huang SH, Su LH, Su YC, Liu WC, Chang SY, Hung CC
J Microbiol Immunol Infect 2021 Oct;54(5):934-943. Epub 2020 Dec 9 doi: 10.1016/j.jmii.2020.11.005. PMID: 33349600
Lymphoproliferative Disorders of the Lung.
Borie R, Wislez M, Antoine M, Cadranel J
Respiration 2017;94(2):157-175. Epub 2017 Jun 14 doi: 10.1159/000477740. PMID: 28609772
Oral HIV-associated Kaposi sarcoma.
Pantanowitz L, Khammissa RA, Lemmer J, Feller L
J Oral Pathol Med 2013 Mar;42(3):201-7. Epub 2012 Jun 5 doi: 10.1111/j.1600-0714.2012.01180.x. PMID: 22672182
Laboratory diagnosis of human herpesvirus 8 infection in humans.
Tedeschi R, Dillner J, De Paoli P
Eur J Clin Microbiol Infect Dis 2002 Dec;21(12):831-44. Epub 2002 Dec 11 doi: 10.1007/s10096-002-0836-8. PMID: 12525917

Clinical prediction guides

Is human herpesvirus 8 infection more common in men than in women? an updated meta-analysis.
Gong H, Zhang S, Dou J, Chen J
BMC Infect Dis 2024 Apr 29;24(1):454. doi: 10.1186/s12879-024-09346-5. PMID: 38684967Free PMC Article
Seroepidemiology of the human herpesvirus 8 infection among people living with HIV in Taiwan, 2014-2018.
Tsai MJ, Sun HY, Hsieh SM, Sheng WH, Chuang YC, Huang YS, Huang SH, Su LH, Su YC, Liu WC, Chang SY, Hung CC
J Microbiol Immunol Infect 2021 Oct;54(5):934-943. Epub 2020 Dec 9 doi: 10.1016/j.jmii.2020.11.005. PMID: 33349600
Human Herpesvirus 8 infection may contribute to oxidative stress in diabetes type 2 patients.
Incani A, Marras L, Serreli G, Ingianni A, Pompei R, Deiana M, Angius F
BMC Res Notes 2020 Feb 13;13(1):75. doi: 10.1186/s13104-020-4935-3. PMID: 32054515Free PMC Article
Is human herpesvirus 8 infection more common in men than in women? Systematic review and meta-analysis.
Begré L, Rohner E, Mbulaiteye SM, Egger M, Bohlius J
Int J Cancer 2016 Aug 15;139(4):776-83. Epub 2016 Apr 26 doi: 10.1002/ijc.30129. PMID: 27062038Free PMC Article
Laboratory diagnosis of human herpesvirus 8 infection in humans.
Tedeschi R, Dillner J, De Paoli P
Eur J Clin Microbiol Infect Dis 2002 Dec;21(12):831-44. Epub 2002 Dec 11 doi: 10.1007/s10096-002-0836-8. PMID: 12525917

Recent systematic reviews

Is human herpesvirus 8 infection more common in men than in women? Systematic review and meta-analysis.
Begré L, Rohner E, Mbulaiteye SM, Egger M, Bohlius J
Int J Cancer 2016 Aug 15;139(4):776-83. Epub 2016 Apr 26 doi: 10.1002/ijc.30129. PMID: 27062038Free PMC Article

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