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Middle cerebral artery stenosis

MedGen UID:
760200
•Concept ID:
C1504568
•
Disease or Syndrome
Synonym: Stenosis of middle cerebral artery
SNOMED CT: Stenosis of middle cerebral artery (21290001000004104)
 
HPO: HP:0012493

Definition

Narrowing or constriction of the inner surface (lumen) of the middle cerebral artery. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Middle cerebral artery stenosis

Conditions with this feature

Aortic aneurysm, familial thoracic 4
MedGen UID:
338704
•Concept ID:
C1851504
•
Disease or Syndrome
Any familial thoracic aortic aneurysm and aortic dissection in which the cause of the disease is a mutation in the MYH11 gene.
See: Condition Record
Aortic aneurysm, familial thoracic 4

Professional guidelines

PubMed

Role of Advanced Hemodynamic Ultrasound Evaluation in the Differential Diagnosis of Middle Cerebral Artery Stenosis: Introducing Morphological Criteria.
Malferrari G, Merli N, Inchingolo V, Siniscalchi A, Laterza D, Monaco D, Arnone G, Zini A, Prada F, Azzini C, Pugliatti M
Ultrasound Med Biol 2023 Nov;49(11):2428-2435. Epub 2023 Aug 5 doi: 10.1016/j.ultrasmedbio.2023.07.004. PMID: 37550172
Transcranial Color-Coded Sonography Criteria for Moderate and Severe Middle Cerebral Artery Stenosis.
Liu R, Li J, Hua Y, Yang J, Zhao Y, Tian X, Ma Y, Zhao W
Ultrasound Med Biol 2021 Jan;47(1):25-32. Epub 2020 Oct 14 doi: 10.1016/j.ultrasmedbio.2020.09.008. PMID: 33069442
Balloon-expandable stents for treatment of symptomatic middle cerebral artery stenosis: Clinical outcomes during long-term follow-up.
Baik SH, Kwak HS, Chung GH, Hwang SB
Interv Neuroradiol 2018 Dec;24(6):666-673. Epub 2018 Jul 10 doi: 10.1177/1591019918786515. PMID: 29991311Free PMC Article

Recent clinical studies

Etiology

Hemodynamics combined with inflammatory indicators exploring relationships between ischemic stroke and symptomatic middle cerebral artery atherosclerotic stenosis.
Wu XB, Liu YA, Huang LX, Guo X, Cai WQ, Luo B, Wang SW
Eur J Med Res 2023 Sep 26;28(1):378. doi: 10.1186/s40001-023-01344-8. PMID: 37752519Free PMC Article
Five-Year Stroke Risk and Its Predictors in Asymptomatic Moyamoya Disease: Asymptomatic Moyamoya Registry (AMORE).
Kuroda S, Yamamoto S, Funaki T, Fujimura M, Kataoka H, Hishikawa T, Takahashi J, Endo H, Nariai T, Osato T, Saito N, Sato N, Hori E, Ito YM, Miyamoto S; AMORE Study Group
Stroke 2023 Jun;54(6):1494-1504. Epub 2023 May 22 doi: 10.1161/STROKEAHA.122.041932. PMID: 37216455
Diffusion spectrum imaging of patients with middle cerebral artery stenosis.
Wan X, Xiao Y, Liu Z
Neuroimage Clin 2022;36:103133. Epub 2022 Aug 5 doi: 10.1016/j.nicl.2022.103133. PMID: 35973283Free PMC Article
Microsurgical treatment of middle cerebral artery stenosis or occlusion: a single center experience and literature review.
Zhang L, Wu C, Wang H, Mao L
BMC Surg 2022 Mar 7;22(1):87. doi: 10.1186/s12893-022-01539-6. PMID: 35255875Free PMC Article
Intracranial arterial stenosis.
Carvalho M, Oliveira A, Azevedo E, Bastos-Leite AJ
J Stroke Cerebrovasc Dis 2014 Apr;23(4):599-609. Epub 2013 Jul 11 doi: 10.1016/j.jstrokecerebrovasdis.2013.06.006. PMID: 23850084

Diagnosis

Hemodynamics combined with inflammatory indicators exploring relationships between ischemic stroke and symptomatic middle cerebral artery atherosclerotic stenosis.
Wu XB, Liu YA, Huang LX, Guo X, Cai WQ, Luo B, Wang SW
Eur J Med Res 2023 Sep 26;28(1):378. doi: 10.1186/s40001-023-01344-8. PMID: 37752519Free PMC Article
Isolated middle cerebral artery stenosis caused by syphilitic vasculitis.
Zhang P, Chen L, Chen S, Wu T, Zhang Y
Sex Health 2023 Feb;20(1):80-82. doi: 10.1071/SH22147. PMID: 36455597
Diagnosis of Middle Cerebral Artery Stenosis Using Transcranial Doppler Images Based on Convolutional Neural Network.
Mei YJ, Hu RT, Lin J, Xu HY, Wu LY, Li HP, Ye ZM, Qin C
World Neurosurg 2022 May;161:e118-e125. Epub 2022 Jan 22 doi: 10.1016/j.wneu.2022.01.068. PMID: 35077885
Transcranial Color-Coded Sonography Criteria for Moderate and Severe Middle Cerebral Artery Stenosis.
Liu R, Li J, Hua Y, Yang J, Zhao Y, Tian X, Ma Y, Zhao W
Ultrasound Med Biol 2021 Jan;47(1):25-32. Epub 2020 Oct 14 doi: 10.1016/j.ultrasmedbio.2020.09.008. PMID: 33069442
Intracranial arterial stenosis.
Carvalho M, Oliveira A, Azevedo E, Bastos-Leite AJ
J Stroke Cerebrovasc Dis 2014 Apr;23(4):599-609. Epub 2013 Jul 11 doi: 10.1016/j.jstrokecerebrovasdis.2013.06.006. PMID: 23850084

Therapy

Long-Term Outcome of Balloon Angioplasty Without Stenting for Symptomatic Middle Cerebral Artery Stenosis.
Ueda T, Takada T, Nogoshi S, Yoshie T, Takaishi S, Fukano T
J Stroke Cerebrovasc Dis 2018 Jul;27(7):1870-1877. Epub 2018 Mar 9 doi: 10.1016/j.jstrokecerebrovasdis.2018.02.019. PMID: 29530461
Assessment of cerebrovascular reserve in unilateral middle cerebral artery stenosis using perfusion CT and CO(2) inhalation tests.
Yang F, Shi W, Shi J, Zhang Y, Yin Y, Shi H, Chen D
Int J Neurosci 2017 Apr;127(4):320-325. Epub 2016 Sep 25 doi: 10.1080/00207454.2016.1235044. PMID: 27619639
Wingspan stenting with modified predilation for symptomatic middle cerebral artery stenosis.
Li J, Zhao ZW, Gao GD, Cheng JM
Catheter Cardiovasc Interv 2011 Aug 1;78(2):286-93. Epub 2011 Apr 8 doi: 10.1002/ccd.22755. PMID: 20824757
Middle cerebral artery stenosis: stenting is one of the options: yes.
Liu M, Li W, Liu ZQ
Stroke 2007 Apr;38(4):1418-9. Epub 2007 Mar 1 doi: 10.1161/01.STR.0000259844.15195.e3. PMID: 17332459
Transluminal angioplasty for middle cerebral artery stenosis in patients with acute ischemic stroke.
Suh DC, Sung KB, Cho YS, Choi CG, Lee HK, Lee JH, Kim JS, Lee MC
AJNR Am J Neuroradiol 1999 Apr;20(4):553-8. PMID: 10319958Free PMC Article

Prognosis

Hemodynamics combined with inflammatory indicators exploring relationships between ischemic stroke and symptomatic middle cerebral artery atherosclerotic stenosis.
Wu XB, Liu YA, Huang LX, Guo X, Cai WQ, Luo B, Wang SW
Eur J Med Res 2023 Sep 26;28(1):378. doi: 10.1186/s40001-023-01344-8. PMID: 37752519Free PMC Article
Five-Year Stroke Risk and Its Predictors in Asymptomatic Moyamoya Disease: Asymptomatic Moyamoya Registry (AMORE).
Kuroda S, Yamamoto S, Funaki T, Fujimura M, Kataoka H, Hishikawa T, Takahashi J, Endo H, Nariai T, Osato T, Saito N, Sato N, Hori E, Ito YM, Miyamoto S; AMORE Study Group
Stroke 2023 Jun;54(6):1494-1504. Epub 2023 May 22 doi: 10.1161/STROKEAHA.122.041932. PMID: 37216455
Prevalence and outcome of young stroke patients with middle cerebral artery stenosis.
Xu W, Zhang X, Chen H, Zhao Z, Zhu M
BMC Neurol 2021 Mar 4;21(1):99. doi: 10.1186/s12883-021-02125-8. PMID: 33663425Free PMC Article
Stenosis length of middle cerebral artery and branch atheromatous disease associated infarct.
Wang J, Wang Y, Chai Z, Xin Y, Wang J, Qiu J
Int J Neurosci 2018 Feb;128(2):133-139. Epub 2017 Sep 22 doi: 10.1080/00207454.2017.1377710. PMID: 28882090
Cortical Microinfarcts in Patients with Middle Cerebral Artery Stenosis.
Leng X, Fang H, Pu Y, Zou X, Pan Y, Soo YOY, Xu Y, Wang C, Zhao X, Wang Y, Wang Y, Liebeskind DS, Wong LKS, Leung TW, Liu L
J Stroke Cerebrovasc Dis 2017 Aug;26(8):1760-1765. Epub 2017 May 15 doi: 10.1016/j.jstrokecerebrovasdis.2017.04.002. PMID: 28522230

Clinical prediction guides

Hemodynamics combined with inflammatory indicators exploring relationships between ischemic stroke and symptomatic middle cerebral artery atherosclerotic stenosis.
Wu XB, Liu YA, Huang LX, Guo X, Cai WQ, Luo B, Wang SW
Eur J Med Res 2023 Sep 26;28(1):378. doi: 10.1186/s40001-023-01344-8. PMID: 37752519Free PMC Article
Five-Year Stroke Risk and Its Predictors in Asymptomatic Moyamoya Disease: Asymptomatic Moyamoya Registry (AMORE).
Kuroda S, Yamamoto S, Funaki T, Fujimura M, Kataoka H, Hishikawa T, Takahashi J, Endo H, Nariai T, Osato T, Saito N, Sato N, Hori E, Ito YM, Miyamoto S; AMORE Study Group
Stroke 2023 Jun;54(6):1494-1504. Epub 2023 May 22 doi: 10.1161/STROKEAHA.122.041932. PMID: 37216455
Microsurgical treatment of middle cerebral artery stenosis or occlusion: a single center experience and literature review.
Zhang L, Wu C, Wang H, Mao L
BMC Surg 2022 Mar 7;22(1):87. doi: 10.1186/s12893-022-01539-6. PMID: 35255875Free PMC Article
Prevalence and outcome of young stroke patients with middle cerebral artery stenosis.
Xu W, Zhang X, Chen H, Zhao Z, Zhu M
BMC Neurol 2021 Mar 4;21(1):99. doi: 10.1186/s12883-021-02125-8. PMID: 33663425Free PMC Article
Stenosis length of middle cerebral artery and branch atheromatous disease associated infarct.
Wang J, Wang Y, Chai Z, Xin Y, Wang J, Qiu J
Int J Neurosci 2018 Feb;128(2):133-139. Epub 2017 Sep 22 doi: 10.1080/00207454.2017.1377710. PMID: 28882090

Recent systematic reviews

Statin treatment and accrual of covert cerebral ischaemia on neuroimaging: a systematic review and meta-analysis of randomized trials.
Katsanos AH, Lioutas VA, Charidimou A, Catanese L, Ng KKH, Perera K, de Sa Boasquevisque D, Tsivgoulis G, Smith EE, Sharma M, Selim MH, Shoamanesh A
Eur J Neurol 2020 Jun;27(6):1023-1027. Epub 2020 Mar 23 doi: 10.1111/ene.14196. PMID: 32133735
The accuracy of transcranial Doppler in the diagnosis of middle cerebral artery stenosis.
Navarro JC, Lao AY, Sharma VK, Tsivgoulis G, Alexandrov AV
Cerebrovasc Dis 2007;23(5-6):325-30. Epub 2007 Jan 30 doi: 10.1159/000099130. PMID: 17268162
Outcome in patients with symptomatic occlusion of the internal carotid artery or intracranial arterial lesions: a meta-analysis of the role of baseline characteristics and type of antithrombotic treatment.
Klijn CJ, Kappelle LJ, Algra A, van Gijn J
Cerebrovasc Dis 2001;12(3):228-34. doi: 10.1159/000047708. PMID: 11641588

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