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Urethra squamous cell carcinoma

MedGen UID:
234975
Concept ID:
C1336890
Neoplastic Process
Synonyms: Epidermoid Carcinoma of the Urethra; epidermoid carcinoma of the urethra; Epidermoid Carcinoma of Urethra; epidermoid carcinoma of urethra; Squamous Cell Carcinoma of the Urethra; squamous cell carcinoma of the urethra; Squamous Cell Carcinoma of Urethra; squamous cell carcinoma of urethra; Urethra Epidermoid Carcinoma; urethra epidermoid carcinoma; Urethra Squamous Cell Carcinoma; urethra squamous cell carcinoma; Urethral Epidermoid Carcinoma; urethral epidermoid carcinoma; urethral squamous cell cancer; Urethral Squamous Cell Carcinoma; urethral squamous cell carcinoma; USCC
 
Monarch Initiative: MONDO:0002764

Definition

A well differentiated, moderately differentiated, or poorly differentiated squamous cell carcinoma that arises from the male or female urethra. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUrethra squamous cell carcinoma

Professional guidelines

PubMed

Chung ASJ, Suarez OA
World J Urol 2020 Dec;38(12):3061-3067. Epub 2019 Dec 5 doi: 10.1007/s00345-019-03030-z. PMID: 31807846
Eng TY, Chen TW, Patel AJ, Vincent JN, Ha CS
Am J Clin Oncol 2018 Sep;41(9):905-908. doi: 10.1097/COC.0000000000000391. PMID: 28537991
Dayyani F, Hoffman K, Eifel P, Guo C, Vikram R, Pagliaro LC, Pettaway C
BJU Int 2014 Jul;114(1):25-31. Epub 2014 May 22 doi: 10.1111/bju.12630. PMID: 24447439

Recent clinical studies

Etiology

Castiglione F, Alnajjar HM, Christodoulidou M, Albersen M, Parnham A, Freeman A, Jameson C, Mitra A, Nigam R, Malone P, Muneer A; Trauma and Reconstructive Urology Working Party of the European Association of Urology Young Academic Urologists
Eur Urol Focus 2021 Jan;7(1):163-169. Epub 2019 Mar 7 doi: 10.1016/j.euf.2019.02.016. PMID: 30853605
Pleunis N, Leermakers MEJ, van der Wurff AA, Klinkhamer PJJM, Ezendam NPM, Boll D, de Hullu JA, Pijnenborg JMA
Eur J Surg Oncol 2018 Oct;44(10):1555-1561. Epub 2018 Jun 6 doi: 10.1016/j.ejso.2018.05.031. PMID: 29934053
Zhang M, Adeniran AJ, Vikram R, Tamboli P, Pettaway C, Bondaruk J, Liu J, Baggerly K, Czerniak B
Hum Pathol 2018 Feb;72:35-44. Epub 2017 Aug 18 doi: 10.1016/j.humpath.2017.08.006. PMID: 28827100Free PMC Article
Agrawal S, Lacy JM, Bagga H, Angermeier KW, Ciezki J, Tendulkar RD, Reddy CA, Wood HM
Urology 2017 Dec;110:172-176. Epub 2017 Sep 4 doi: 10.1016/j.urology.2017.08.036. PMID: 28882777
Salom EM, Penalver M
Curr Treat Options Oncol 2002 Apr;3(2):143-53. doi: 10.1007/s11864-002-0060-x. PMID: 12057077

Diagnosis

Zhang M, Adeniran AJ, Vikram R, Tamboli P, Pettaway C, Bondaruk J, Liu J, Baggerly K, Czerniak B
Hum Pathol 2018 Feb;72:35-44. Epub 2017 Aug 18 doi: 10.1016/j.humpath.2017.08.006. PMID: 28827100Free PMC Article
Zargar-Shoshtari K, Sexton WJ, Poch MA
Urol Clin North Am 2016 Nov;43(4):515-521. doi: 10.1016/j.ucl.2016.06.012. PMID: 27717437
Becker K
Dtsch Arztebl Int 2011 Jan;108(4):53-8. Epub 2011 Jan 28 doi: 10.3238/arztebl.2011.053. PMID: 21307992Free PMC Article
Wong JT, Wasserman NF, Padurean AM
Radiographics 2004 May-Jun;24(3):855-60. doi: 10.1148/rg.243035153. PMID: 15143234
Salom EM, Penalver M
Curr Treat Options Oncol 2002 Apr;3(2):143-53. doi: 10.1007/s11864-002-0060-x. PMID: 12057077

Therapy

Castiglione F, Alnajjar HM, Christodoulidou M, Albersen M, Parnham A, Freeman A, Jameson C, Mitra A, Nigam R, Malone P, Muneer A; Trauma and Reconstructive Urology Working Party of the European Association of Urology Young Academic Urologists
Eur Urol Focus 2021 Jan;7(1):163-169. Epub 2019 Mar 7 doi: 10.1016/j.euf.2019.02.016. PMID: 30853605
Gakis G, Witjes JA, Compérat E, Cowan NC, De Santis M, Lebret T, Ribal MJ, Sherif AM; European Association of Urology
Eur Urol 2013 Nov;64(5):823-30. Epub 2013 Apr 2 doi: 10.1016/j.eururo.2013.03.044. PMID: 23582479
Trabulsi EJ, Hoffman-Censits J
Urol Clin North Am 2010 Aug;37(3):467-74. doi: 10.1016/j.ucl.2010.04.010. PMID: 20674701
Salom EM, Penalver M
Curr Treat Options Oncol 2002 Apr;3(2):143-53. doi: 10.1007/s11864-002-0060-x. PMID: 12057077
Das S, Tunuguntla HS
World J Urol 2000 Dec;18(6):382-7. doi: 10.1007/PL00007083. PMID: 11204255

Prognosis

Gadducci A, Aletti GD
Gynecol Oncol 2020 Jul;158(1):208-217. Epub 2020 May 25 doi: 10.1016/j.ygyno.2020.05.021. PMID: 32460996
Pleunis N, Leermakers MEJ, van der Wurff AA, Klinkhamer PJJM, Ezendam NPM, Boll D, de Hullu JA, Pijnenborg JMA
Eur J Surg Oncol 2018 Oct;44(10):1555-1561. Epub 2018 Jun 6 doi: 10.1016/j.ejso.2018.05.031. PMID: 29934053
Corbishley CM, Rajab RM, Watkin NA
Semin Diagn Pathol 2015 May;32(3):238-44. Epub 2014 Dec 25 doi: 10.1053/j.semdp.2014.12.015. PMID: 25656527
Velazquez EF, Cubilla AL
Anal Quant Cytol Histol 2007 Aug;29(4):185-98. PMID: 17879626
Salom EM, Penalver M
Curr Treat Options Oncol 2002 Apr;3(2):143-53. doi: 10.1007/s11864-002-0060-x. PMID: 12057077

Clinical prediction guides

Deng F, Kong MX, Lai J
Anticancer Res 2022 Jul;42(7):3601-3605. doi: 10.21873/anticanres.15847. PMID: 35790255
Werntz RP, Riedinger CB, Fantus RJ, Smith ZL, Packiam VT, Adamsky MA, Smith N, Steinberg GD
Urol Oncol 2018 Dec;36(12):526.e1-526.e6. Epub 2018 Nov 13 doi: 10.1016/j.urolonc.2018.09.014. PMID: 30446445
Pleunis N, Leermakers MEJ, van der Wurff AA, Klinkhamer PJJM, Ezendam NPM, Boll D, de Hullu JA, Pijnenborg JMA
Eur J Surg Oncol 2018 Oct;44(10):1555-1561. Epub 2018 Jun 6 doi: 10.1016/j.ejso.2018.05.031. PMID: 29934053
Zhang M, Adeniran AJ, Vikram R, Tamboli P, Pettaway C, Bondaruk J, Liu J, Baggerly K, Czerniak B
Hum Pathol 2018 Feb;72:35-44. Epub 2017 Aug 18 doi: 10.1016/j.humpath.2017.08.006. PMID: 28827100Free PMC Article
Gakis G, Witjes JA, Compérat E, Cowan NC, De Santis M, Lebret T, Ribal MJ, Sherif AM; European Association of Urology
Eur Urol 2013 Nov;64(5):823-30. Epub 2013 Apr 2 doi: 10.1016/j.eururo.2013.03.044. PMID: 23582479

Recent systematic reviews

Andrews AR, Kakadekar A, Schmidt RL, Murugan P, Greene DN
Arch Pathol Lab Med 2022 Jan 2;146(2):252-261. doi: 10.5858/arpa.2020-0704-RA. PMID: 33983412
Janisch F, Abufaraj M, Fajkovic H, Kimura S, Iwata T, Nyirady P, Rink M, Shariat SF
Eur Urol Focus 2019 Sep;5(5):722-734. Epub 2019 Jul 13 doi: 10.1016/j.euf.2019.07.001. PMID: 31307949

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