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Central Nervous System Kaposi Sarcoma

MedGen UID:
232677
•Concept ID:
C1334318
•
Neoplastic Process
Synonyms: CNS Kaposi Sarcoma; Kaposi Sarcoma of Central Nervous System; Kaposi Sarcoma of CNS; Kaposi Sarcoma of the Central Nervous System; Kaposi Sarcoma of the CNS

Definition

A Kaposi sarcoma arising from the brain, spinal cord, or meninges. [from NCI]

Professional guidelines

PubMed

Medical management of AIDS patients. Ophthalmic problems.
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Recent clinical studies

Etiology

Care of Patients With HIV Infection: Medical Complications and Comorbidities.
Bolduc P, Roder N, Colgate E, Cheeseman SH
FP Essent 2016 Apr;443:16-22. PMID: 27092563
Malignancies in HIV/AIDS: from epidemiology to therapeutic challenges.
Rubinstein PG, Aboulafia DM, Zloza A
AIDS 2014 Feb 20;28(4):453-65. doi: 10.1097/QAD.0000000000000071. PMID: 24401642Free PMC Article
Cancer biomarkers in HIV patients.
Ambinder RF, Bhatia K, Martinez-Maza O, Mitsuyasu R
Curr Opin HIV AIDS 2010 Nov;5(6):531-7. doi: 10.1097/COH.0b013e32833f327e. PMID: 20978397Free PMC Article
Human herpesvirus 6: An emerging pathogen.
Campadelli-Fiume G, Mirandola P, Menotti L
Emerg Infect Dis 1999 May-Jun;5(3):353-66. doi: 10.3201/eid0503.990306. PMID: 10341172Free PMC Article
Acquired immunodeficiency syndrome (AIDS).
Gong V
Am J Emerg Med 1984 Jul;2(4):336-46. doi: 10.1016/0735-6757(84)90131-1. PMID: 6097278

Diagnosis

Care of Patients With HIV Infection: Medical Complications and Comorbidities.
Bolduc P, Roder N, Colgate E, Cheeseman SH
FP Essent 2016 Apr;443:16-22. PMID: 27092563
Kaposi sarcoma in unusual locations.
Pantanowitz L, Dezube BJ
BMC Cancer 2008 Jul 7;8:190. doi: 10.1186/1471-2407-8-190. PMID: 18605999Free PMC Article
Immunodeficiency-associated lymphoproliferative disorders.
Knowles DM
Mod Pathol 1999 Feb;12(2):200-17. PMID: 10071343
Human herpesvirus 6.
Braun DK, Dominguez G, Pellett PE
Clin Microbiol Rev 1997 Jul;10(3):521-67. doi: 10.1128/CMR.10.3.521. PMID: 9227865Free PMC Article
Acquired immunodeficiency syndrome (AIDS).
Gong V
Am J Emerg Med 1984 Jul;2(4):336-46. doi: 10.1016/0735-6757(84)90131-1. PMID: 6097278

Therapy

Flavonoids Target Human Herpesviruses That Infect the Nervous System: Mechanisms of Action and Therapeutic Insights.
Šudomová M, Berchová-Bímová K, Mazurakova A, Šamec D, Kubatka P, Hassan STS
Viruses 2022 Mar 13;14(3) doi: 10.3390/v14030592. PMID: 35336999Free PMC Article
HIV-associated lymphomas and gamma-herpesviruses.
Carbone A, Cesarman E, Spina M, Gloghini A, Schulz TF
Blood 2009 Feb 5;113(6):1213-24. Epub 2008 Oct 27 doi: 10.1182/blood-2008-09-180315. PMID: 18955561
Human herpesvirus 6.
Caserta MT, Mock DJ, Dewhurst S
Clin Infect Dis 2001 Sep 15;33(6):829-33. Epub 2001 Aug 10 doi: 10.1086/322691. PMID: 11512088
Immunodeficiency-associated lymphoproliferative disorders.
Knowles DM
Mod Pathol 1999 Feb;12(2):200-17. PMID: 10071343
Acquired immunodeficiency syndrome (AIDS).
Gong V
Am J Emerg Med 1984 Jul;2(4):336-46. doi: 10.1016/0735-6757(84)90131-1. PMID: 6097278

Prognosis

Malignancies in HIV/AIDS: from epidemiology to therapeutic challenges.
Rubinstein PG, Aboulafia DM, Zloza A
AIDS 2014 Feb 20;28(4):453-65. doi: 10.1097/QAD.0000000000000071. PMID: 24401642Free PMC Article
Human immunodeficiency virus-associated malignancies: a therapeutic update.
Malfitano A, Barbaro G, Perretti A, Barbarini G
Curr HIV Res 2012 Mar;10(2):123-32. doi: 10.2174/157016212799937227. PMID: 22329518
HIV-associated lymphomas and gamma-herpesviruses.
Carbone A, Cesarman E, Spina M, Gloghini A, Schulz TF
Blood 2009 Feb 5;113(6):1213-24. Epub 2008 Oct 27 doi: 10.1182/blood-2008-09-180315. PMID: 18955561
HIV infection and AIDS.
Lloyd A
P N G Med J 1996 Sep;39(3):174-80. PMID: 9795558
Acquired immune deficiency syndrome: review.
Scully C, Cawson RA, Porter SR
Br Dent J 1986 Jul 19;161(2):53-60. doi: 10.1038/sj.bdj.4805895. PMID: 3524629

Clinical prediction guides

Epidemiology of Cancers in Zambia: A significant variation in Cancer incidence and prevalence across the nation.
Kalubula M, Shen H, Makasa M, Liu L
Malawi Med J 2021 Sep;33(3):186-195. doi: 10.4314/mmj.v33i3.6. PMID: 35233276Free PMC Article
Human immunodeficiency virus-associated malignancies: a therapeutic update.
Malfitano A, Barbaro G, Perretti A, Barbarini G
Curr HIV Res 2012 Mar;10(2):123-32. doi: 10.2174/157016212799937227. PMID: 22329518
HIV, EBV and KSHV: viral cooperation in the pathogenesis of human malignancies.
da Silva SR, de Oliveira DE
Cancer Lett 2011 Jun 28;305(2):175-85. Epub 2011 Mar 12 doi: 10.1016/j.canlet.2011.02.007. PMID: 21402436
Interactions between endothelial cells and HIV-1.
Bussolino F, Mitola S, Serini G, Barillari G, Ensoli B
Int J Biochem Cell Biol 2001 Apr;33(4):371-90. doi: 10.1016/s1357-2725(01)00024-3. PMID: 11312107
HHV-8/KSHV is not associated with AIDS-related primary central nervous system lymphoma.
Antinori A, Larocca LM, Fassone L, Cattani P, Capello D, Cingolani A, Saglio G, Fadda G, Gaidano G, Ortona L
Brain Pathol 1999 Apr;9(2):199-208. doi: 10.1111/j.1750-3639.1999.tb00218.x. PMID: 10219737Free PMC Article

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