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Grade 1 Colon Adenocarcinoma

MedGen UID:
272681
Concept ID:
C1333866
Neoplastic Process
Synonyms: Grade I Colon Adenocarcinoma; Well Differentiated Colon Adenocarcinoma

Definition

A colon adenocarcinoma characterized by the presence of a malignant cellular infiltrate with more than 95% glandular formation. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade 1 Colon Adenocarcinoma

Professional guidelines

PubMed

Rutter MD, East J, Rees CJ, Cripps N, Docherty J, Dolwani S, Kaye PV, Monahan KJ, Novelli MR, Plumb A, Saunders BP, Thomas-Gibson S, Tolan DJM, Whyte S, Bonnington S, Scope A, Wong R, Hibbert B, Marsh J, Moores B, Cross A, Sharp L
Gut 2020 Feb;69(2):201-223. Epub 2019 Nov 27 doi: 10.1136/gutjnl-2019-319858. PMID: 31776230Free PMC Article
Pimentel-Nunes P, Dinis-Ribeiro M, Ponchon T, Repici A, Vieth M, De Ceglie A, Amato A, Berr F, Bhandari P, Bialek A, Conio M, Haringsma J, Langner C, Meisner S, Messmann H, Morino M, Neuhaus H, Piessevaux H, Rugge M, Saunders BP, Robaszkiewicz M, Seewald S, Kashin S, Dumonceau JM, Hassan C, Deprez PH
Endoscopy 2015 Sep;47(9):829-54. Epub 2015 Aug 28 doi: 10.1055/s-0034-1392882. PMID: 26317585
Gonzalez QH, Heslin MJ, Dávila-Cervantes A, Alvarez-Tostado J, de los Monteros AE, Shore G, Vickers SM
Am Surg 2008 Mar;74(3):214-6. PMID: 18376684

Recent clinical studies

Etiology

Morton D, Seymour M, Magill L, Handley K, Glasbey J, Glimelius B, Palmer A, Seligmann J, Laurberg S, Murakami K, West N, Quirke P, Gray R; FOxTROT Collaborative Group
J Clin Oncol 2023 Mar 10;41(8):1541-1552. Epub 2023 Jan 19 doi: 10.1200/JCO.22.00046. PMID: 36657089Free PMC Article
Click B, Pinsky PF, Hickey T, Doroudi M, Schoen RE
JAMA 2018 May 15;319(19):2021-2031. doi: 10.1001/jama.2018.5809. PMID: 29800214Free PMC Article
Marisa L, de Reyniès A, Duval A, Selves J, Gaub MP, Vescovo L, Etienne-Grimaldi MC, Schiappa R, Guenot D, Ayadi M, Kirzin S, Chazal M, Fléjou JF, Benchimol D, Berger A, Lagarde A, Pencreach E, Piard F, Elias D, Parc Y, Olschwang S, Milano G, Laurent-Puig P, Boige V
PLoS Med 2013;10(5):e1001453. Epub 2013 May 21 doi: 10.1371/journal.pmed.1001453. PMID: 23700391Free PMC Article
André T, Boni C, Mounedji-Boudiaf L, Navarro M, Tabernero J, Hickish T, Topham C, Zaninelli M, Clingan P, Bridgewater J, Tabah-Fisch I, de Gramont A; Multicenter International Study of Oxaliplatin/5-Fluorouracil/Leucovorin in the Adjuvant Treatment of Colon Cancer (MOSAIC) Investigators
N Engl J Med 2004 Jun 3;350(23):2343-51. doi: 10.1056/NEJMoa032709. PMID: 15175436
Haggitt RC, Glotzbach RE, Soffer EE, Wruble LD
Gastroenterology 1985 Aug;89(2):328-36. doi: 10.1016/0016-5085(85)90333-6. PMID: 4007423

Diagnosis

Narayanan V, Pavithra V, Dhanapal D, Sundaram S, Narayanan CD
Indian J Pathol Microbiol 2022 Oct-Dec;65(4):791-795. doi: 10.4103/ijpm.ijpm_112_21. PMID: 36308182
Cuk P, Kjær MD, Mogensen CB, Nielsen MF, Pedersen AK, Ellebæk MB
Surg Endosc 2022 Jan;36(1):32-46. Epub 2021 Nov 1 doi: 10.1007/s00464-021-08782-7. PMID: 34724576Free PMC Article
Mañas A, Yao Q, Davis A, Basheer S, Beatty E, Zhang H, Li J, Nelson A, Zhang H, Xiang J
Histochem Cell Biol 2020 Jul;154(1):41-53. Epub 2020 Mar 21 doi: 10.1007/s00418-020-01874-w. PMID: 32200452Free PMC Article
Click B, Pinsky PF, Hickey T, Doroudi M, Schoen RE
JAMA 2018 May 15;319(19):2021-2031. doi: 10.1001/jama.2018.5809. PMID: 29800214Free PMC Article
Marisa L, de Reyniès A, Duval A, Selves J, Gaub MP, Vescovo L, Etienne-Grimaldi MC, Schiappa R, Guenot D, Ayadi M, Kirzin S, Chazal M, Fléjou JF, Benchimol D, Berger A, Lagarde A, Pencreach E, Piard F, Elias D, Parc Y, Olschwang S, Milano G, Laurent-Puig P, Boige V
PLoS Med 2013;10(5):e1001453. Epub 2013 May 21 doi: 10.1371/journal.pmed.1001453. PMID: 23700391Free PMC Article

Therapy

Yu M, Cai Z, Zhou H, Fingerhut A, He Z, Xue P, Song H, Yang X, Cheng X, Zhang S, Xu X, Zhong H, Abuduaini N, Liu J, Wang X, Feng B
Future Oncol 2023 Dec;19(40):2641-2650. Epub 2023 Dec 18 doi: 10.2217/fon-2023-0769. PMID: 38108112
Kato T, Kudo T, Kagawa Y, Murata K, Ota H, Noura S, Hasegawa J, Tamagawa H, Ohta K, Ikenaga M, Miyazaki S, Komori T, Uemura M, Nishimura J, Hata T, Matsuda C, Satoh T, Mizushima T, Ohno Y, Yamamoto H, Doki Y, Eguchi H
Sci Rep 2023 Feb 9;13(1):2331. doi: 10.1038/s41598-022-24057-0. PMID: 36759648Free PMC Article
Morton D, Seymour M, Magill L, Handley K, Glasbey J, Glimelius B, Palmer A, Seligmann J, Laurberg S, Murakami K, West N, Quirke P, Gray R; FOxTROT Collaborative Group
J Clin Oncol 2023 Mar 10;41(8):1541-1552. Epub 2023 Jan 19 doi: 10.1200/JCO.22.00046. PMID: 36657089Free PMC Article
Eaton JE, Talwalkar JA, Lazaridis KN, Gores GJ, Lindor KD
Gastroenterology 2013 Sep;145(3):521-36. Epub 2013 Jul 1 doi: 10.1053/j.gastro.2013.06.052. PMID: 23827861Free PMC Article
André T, Boni C, Mounedji-Boudiaf L, Navarro M, Tabernero J, Hickish T, Topham C, Zaninelli M, Clingan P, Bridgewater J, Tabah-Fisch I, de Gramont A; Multicenter International Study of Oxaliplatin/5-Fluorouracil/Leucovorin in the Adjuvant Treatment of Colon Cancer (MOSAIC) Investigators
N Engl J Med 2004 Jun 3;350(23):2343-51. doi: 10.1056/NEJMoa032709. PMID: 15175436

Prognosis

Wang Y, Zhang Y, Wang F, Li T, Song X, Shi H, Du J, Zhang H, Jing H, Han J, Tong D, Zhang J
Sci Rep 2022 Nov 2;12(1):18518. doi: 10.1038/s41598-022-21328-8. PMID: 36323715Free PMC Article
Click B, Pinsky PF, Hickey T, Doroudi M, Schoen RE
JAMA 2018 May 15;319(19):2021-2031. doi: 10.1001/jama.2018.5809. PMID: 29800214Free PMC Article
Omazic B, Remberger M, Barkholt L, Söderdahl G, Potácová Z, Wersäll P, Ericzon BG, Mattsson J, Ringdén O
Biol Blood Marrow Transplant 2016 Apr;22(4):676-681. Epub 2015 Dec 29 doi: 10.1016/j.bbmt.2015.12.017. PMID: 26740375
Marisa L, de Reyniès A, Duval A, Selves J, Gaub MP, Vescovo L, Etienne-Grimaldi MC, Schiappa R, Guenot D, Ayadi M, Kirzin S, Chazal M, Fléjou JF, Benchimol D, Berger A, Lagarde A, Pencreach E, Piard F, Elias D, Parc Y, Olschwang S, Milano G, Laurent-Puig P, Boige V
PLoS Med 2013;10(5):e1001453. Epub 2013 May 21 doi: 10.1371/journal.pmed.1001453. PMID: 23700391Free PMC Article
Chaurand P, Schwartz SA, Reyzer ML, Caprioli RM
Toxicol Pathol 2005;33(1):92-101. doi: 10.1080/01926230590881862. PMID: 15805060

Clinical prediction guides

Ma Z, Yang S, Yang Y, Luo J, Zhou Y, Yang H
Front Endocrinol (Lausanne) 2023;14:1073360. Epub 2023 Jul 31 doi: 10.3389/fendo.2023.1073360. PMID: 37583430Free PMC Article
Morton D, Seymour M, Magill L, Handley K, Glasbey J, Glimelius B, Palmer A, Seligmann J, Laurberg S, Murakami K, West N, Quirke P, Gray R; FOxTROT Collaborative Group
J Clin Oncol 2023 Mar 10;41(8):1541-1552. Epub 2023 Jan 19 doi: 10.1200/JCO.22.00046. PMID: 36657089Free PMC Article
Cuk P, Kjær MD, Mogensen CB, Nielsen MF, Pedersen AK, Ellebæk MB
Surg Endosc 2022 Jan;36(1):32-46. Epub 2021 Nov 1 doi: 10.1007/s00464-021-08782-7. PMID: 34724576Free PMC Article
Click B, Pinsky PF, Hickey T, Doroudi M, Schoen RE
JAMA 2018 May 15;319(19):2021-2031. doi: 10.1001/jama.2018.5809. PMID: 29800214Free PMC Article
Chaurand P, Schwartz SA, Reyzer ML, Caprioli RM
Toxicol Pathol 2005;33(1):92-101. doi: 10.1080/01926230590881862. PMID: 15805060

Recent systematic reviews

Hassan C, Rizkala T, Mori Y, Spadaccini M, Misawa M, Antonelli G, Rondonotti E, Dekker E, Houwen BBSL, Pech O, Baumer S, Li JW, von Renteln D, Haumesser C, Maselli R, Facciorusso A, Correale L, Menini M, Schilirò A, Khalaf K, Patel H, Radadiya DK, Bhandari P, Kudo SE, Sultan S, Vandvik PO, Sharma P, Rex DK, Foroutan F, Repici A; CADx analysis study group
Lancet Gastroenterol Hepatol 2024 Nov;9(11):1010-1019. Epub 2024 Sep 17 doi: 10.1016/S2468-1253(24)00222-X. PMID: 39303733
Piozzi GN, Rusli SM, Baek SJ, Kwak JM, Kim J, Kim SH
Eur J Surg Oncol 2022 Apr;48(4):718-726. Epub 2021 Dec 4 doi: 10.1016/j.ejso.2021.12.005. PMID: 34893366
Cuk P, Kjær MD, Mogensen CB, Nielsen MF, Pedersen AK, Ellebæk MB
Surg Endosc 2022 Jan;36(1):32-46. Epub 2021 Nov 1 doi: 10.1007/s00464-021-08782-7. PMID: 34724576Free PMC Article
Hassan C, Spadaccini M, Iannone A, Maselli R, Jovani M, Chandrasekar VT, Antonelli G, Yu H, Areia M, Dinis-Ribeiro M, Bhandari P, Sharma P, Rex DK, Rösch T, Wallace M, Repici A
Gastrointest Endosc 2021 Jan;93(1):77-85.e6. Epub 2020 Jun 26 doi: 10.1016/j.gie.2020.06.059. PMID: 32598963
Morano WF, Gleeson EM, Sullivan SH, Padmanaban V, Mapow BL, Shewokis PA, Esquivel J, Bowne WB
Am Surg 2018 Feb 1;84(2):273-281. PMID: 29580358

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