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Gastric cardia carcinoma

MedGen UID:
234295
•Concept ID:
C1333763
•
Neoplastic Process
Synonyms: Cancer of Gastric Cardia; cancer of gastric cardia; Cancer of the Gastric Cardia; cancer of the gastric cardia; Carcinoma of Cardia of Stomach; carcinoma of cardia of stomach; Carcinoma of Gastric Cardia; carcinoma of gastric cardia; Carcinoma of the Cardia of the Stomach; carcinoma of the cardia of the stomach; Carcinoma of the Gastric Cardia; carcinoma of the gastric cardia; cardia of stomach carcinoma; gastric cardia (stomach) cancer; Gastric Cardia Cancer; gastric cardia cancer; Gastric Cardia Carcinoma; gastric cardia carcinoma
 
Monarch Initiative: MONDO:0003834

Definition

A carcinoma that arises from the gastric cardia. [from NCI]

Professional guidelines

PubMed

Characterization of 500 Chinese patients with cervical esophageal cancer by clinicopathological and treatment outcomes.
Chen P, Zhao X, Zhou F, Song X, Hu S, Jin Y, Wang X, Han X, Fan Z, Wang R, Li B, Han W, Wang P, Li J, Wan L, Zhang L, Bao Q, Chang F, Qin Y, Chang Z, Ku J, Yang H, Yuan L, Ren J, Li X, Wang L
Cancer Biol Med 2020 Feb 15;17(1):219-226. doi: 10.20892/j.issn.2095-3941.2019.0268. PMID: 32296589Free PMC Article
Clinical relevance of iceA and babA2 genotypes of Helicobacter pylori in a Shanghai population.
Han YH, Liu WZ, Zhu HY, Xiao SD
Chin J Dig Dis 2004;5(4):181-5. doi: 10.1111/j.1443-9573.2004.00175.x. PMID: 15612889

Recent clinical studies

Etiology

Mucosal esophageal carcinoma following endoscopic submucosal dissection with giant gastric metastasis: A case report and review of literature.
Yang MQ, Sun MJ, Zhang HJ
World J Gastroenterol 2023 Nov 28;29(44):5935-5944. doi: 10.3748/wjg.v29.i44.5935. PMID: 38111508Free PMC Article
Combined risk factors and risk of upper gastrointestinal cancer mortality in the Linxian general population.
Yang H, Wang XK, Wang JB, Zhao FH, Fan JH, Qiao YL, Taylor PR, Abnet CC
Int J Cancer 2022 Nov 1;151(9):1462-1473. Epub 2022 Jun 25 doi: 10.1002/ijc.34160. PMID: 35689438
Oral leukoplakia and the long-term risk of upper gastrointestinal cancer deaths in the Linxian dysplasia population.
Yang H, Zhang S, Wang J, Fan J, Qiao Y, Taylor PR
Thorac Cancer 2020 Oct;11(10):2804-2811. Epub 2020 Aug 18 doi: 10.1111/1759-7714.13595. PMID: 32808454Free PMC Article
Delayed gastric emptying after esophagectomy for malignancy.
Li B, Zhang JH, Wang C, Song TN, Wang ZQ, Gou YJ, Yang JB, Wei XP
J Laparoendosc Adv Surg Tech A 2014 May;24(5):306-11. Epub 2014 Apr 17 doi: 10.1089/lap.2013.0416. PMID: 24742329
Nutrition in the prevention of gastrointestinal cancer.
van den Brandt PA, Goldbohm RA
Best Pract Res Clin Gastroenterol 2006;20(3):589-603. doi: 10.1016/j.bpg.2006.04.001. PMID: 16782531

Diagnosis

Primary gastric epithelioid angiosarcoma: A case report of diagnostic biopsy pitfall.
Zhou N, Yang L, Li T, Chen L, Jia R, Chen Y
Medicine (Baltimore) 2024 Oct 4;103(40):e39719. doi: 10.1097/MD.0000000000039719. PMID: 39465747Free PMC Article
Characterization of 500 Chinese patients with cervical esophageal cancer by clinicopathological and treatment outcomes.
Chen P, Zhao X, Zhou F, Song X, Hu S, Jin Y, Wang X, Han X, Fan Z, Wang R, Li B, Han W, Wang P, Li J, Wan L, Zhang L, Bao Q, Chang F, Qin Y, Chang Z, Ku J, Yang H, Yuan L, Ren J, Li X, Wang L
Cancer Biol Med 2020 Feb 15;17(1):219-226. doi: 10.20892/j.issn.2095-3941.2019.0268. PMID: 32296589Free PMC Article
Coexistence of gastrointestinal stromal tumor, esophageal and gastric cardia carcinomas.
Zhou Y, Wu XD, Shi Q, Jia J
World J Gastroenterol 2013 Mar 28;19(12):2005-8. doi: 10.3748/wjg.v19.i12.2005. PMID: 23569349Free PMC Article
Increased incidence and survival for oesophageal cancer but not for gastric cardia cancer in the Netherlands.
Dikken JL, Lemmens VE, Wouters MW, Wijnhoven BP, Siersema PD, Nieuwenhuijzen GA, van Sandick JW, Cats A, Verheij M, Coebergh JW, van de Velde CJ
Eur J Cancer 2012 Jul;48(11):1624-32. Epub 2012 Feb 6 doi: 10.1016/j.ejca.2012.01.009. PMID: 22317953
Unchanging trend of adenocarcinoma of the esophagus and gastric cardia in Taiwan: a 15-year experience in a single center.
Chang SS, Lu CL, Chao JY, Chao Y, Yen SH, Wang SS, Chang FY, Lee SD
Dig Dis Sci 2002 Apr;47(4):735-40. doi: 10.1023/a:1014771429546. PMID: 11991601

Therapy

Proportion of cancer in a Middle eastern country attributable to established risk factors.
Charafeddine MA, Olson SH, Mukherji D, Temraz SN, Abou-Alfa GK, Shamseddine AI
BMC Cancer 2017 May 18;17(1):337. doi: 10.1186/s12885-017-3304-7. PMID: 28521815Free PMC Article
Delayed gastric emptying after esophagectomy for malignancy.
Li B, Zhang JH, Wang C, Song TN, Wang ZQ, Gou YJ, Yang JB, Wei XP
J Laparoendosc Adv Surg Tech A 2014 May;24(5):306-11. Epub 2014 Apr 17 doi: 10.1089/lap.2013.0416. PMID: 24742329
Double contrast-enhanced two-dimensional and three-dimensional ultrasonography for evaluation of gastric lesions.
Shi H, Yu XH, Guo XZ, Guo Y, Zhang H, Qian B, Wei ZR, Li L, Wang XC, Kong ZX
World J Gastroenterol 2012 Aug 21;18(31):4136-44. doi: 10.3748/wjg.v18.i31.4136. PMID: 22919245Free PMC Article
Clinical application of layered anastomosis during esophagogastrostomy.
Zhu ZJ, Zhao YF, Chen LQ, Hu Y, Liu LX, Wang Y, Kou YL
World J Surg 2008 Apr;32(4):583-8. doi: 10.1007/s00268-007-9396-5. PMID: 18210181
Nutrition in the prevention of gastrointestinal cancer.
van den Brandt PA, Goldbohm RA
Best Pract Res Clin Gastroenterol 2006;20(3):589-603. doi: 10.1016/j.bpg.2006.04.001. PMID: 16782531

Prognosis

Mucosal esophageal carcinoma following endoscopic submucosal dissection with giant gastric metastasis: A case report and review of literature.
Yang MQ, Sun MJ, Zhang HJ
World J Gastroenterol 2023 Nov 28;29(44):5935-5944. doi: 10.3748/wjg.v29.i44.5935. PMID: 38111508Free PMC Article
Characterization of 500 Chinese patients with cervical esophageal cancer by clinicopathological and treatment outcomes.
Chen P, Zhao X, Zhou F, Song X, Hu S, Jin Y, Wang X, Han X, Fan Z, Wang R, Li B, Han W, Wang P, Li J, Wan L, Zhang L, Bao Q, Chang F, Qin Y, Chang Z, Ku J, Yang H, Yuan L, Ren J, Li X, Wang L
Cancer Biol Med 2020 Feb 15;17(1):219-226. doi: 10.20892/j.issn.2095-3941.2019.0268. PMID: 32296589Free PMC Article
Delayed gastric emptying after esophagectomy for malignancy.
Li B, Zhang JH, Wang C, Song TN, Wang ZQ, Gou YJ, Yang JB, Wei XP
J Laparoendosc Adv Surg Tech A 2014 May;24(5):306-11. Epub 2014 Apr 17 doi: 10.1089/lap.2013.0416. PMID: 24742329
Increased incidence and survival for oesophageal cancer but not for gastric cardia cancer in the Netherlands.
Dikken JL, Lemmens VE, Wouters MW, Wijnhoven BP, Siersema PD, Nieuwenhuijzen GA, van Sandick JW, Cats A, Verheij M, Coebergh JW, van de Velde CJ
Eur J Cancer 2012 Jul;48(11):1624-32. Epub 2012 Feb 6 doi: 10.1016/j.ejca.2012.01.009. PMID: 22317953
Clinicopathologic and protein expression differences between cardia carcinoma and noncardia carcinoma of the stomach.
Kim MA, Lee HS, Yang HK, Kim WH
Cancer 2005 Apr 1;103(7):1439-46. doi: 10.1002/cncr.20966. PMID: 15726543

Clinical prediction guides

Combined risk factors and risk of upper gastrointestinal cancer mortality in the Linxian general population.
Yang H, Wang XK, Wang JB, Zhao FH, Fan JH, Qiao YL, Taylor PR, Abnet CC
Int J Cancer 2022 Nov 1;151(9):1462-1473. Epub 2022 Jun 25 doi: 10.1002/ijc.34160. PMID: 35689438
Oral leukoplakia and the long-term risk of upper gastrointestinal cancer deaths in the Linxian dysplasia population.
Yang H, Zhang S, Wang J, Fan J, Qiao Y, Taylor PR
Thorac Cancer 2020 Oct;11(10):2804-2811. Epub 2020 Aug 18 doi: 10.1111/1759-7714.13595. PMID: 32808454Free PMC Article
Fresh fruit consumption may decrease the long-term risk of esophageal cancer mortality: A 30-year follow-up study in the Linxian Dysplasia Nutrition Intervention trial (NIT).
Yang H, Zhang S, Yan H, Wang J, Fan J, Qiao Y, Taylor PR
Thorac Cancer 2020 Jul;11(7):1918-1926. Epub 2020 May 29 doi: 10.1111/1759-7714.13482. PMID: 32469462Free PMC Article
Delayed gastric emptying after esophagectomy for malignancy.
Li B, Zhang JH, Wang C, Song TN, Wang ZQ, Gou YJ, Yang JB, Wei XP
J Laparoendosc Adv Surg Tech A 2014 May;24(5):306-11. Epub 2014 Apr 17 doi: 10.1089/lap.2013.0416. PMID: 24742329
Gastric cardia carcinoma is associated with the promoter -77T>C gene polymorphism of X-ray cross-complementing group 1 (XRCC1).
Corso G, Marrelli D, Pedrazzani C, Machado JC, Mancini S, Seruca R, Roviello F
J Gastrointest Surg 2009 Dec;13(12):2233-8. Epub 2009 Aug 7 doi: 10.1007/s11605-009-0980-x. PMID: 19662459

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