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Esophageal basaloid carcinoma

MedGen UID:
232156
•Concept ID:
C1333443
•
Neoplastic Process
Synonyms: Basaloid Squamous Carcinoma of Esophagus; basaloid squamous carcinoma of esophagus; basaloid squamous carcinoma of oesophagus; Basaloid Squamous Carcinoma of the Esophagus; basaloid squamous carcinoma of the esophagus; basaloid squamous carcinoma of the oesophagus; esophageal basaloid cancer; Esophageal Basaloid Carcinoma; esophageal basaloid carcinoma; Esophageal Basaloid Squamous Cell Carcinoma; esophageal basaloid squamous cell carcinoma
 
Monarch Initiative: MONDO:0004093

Definition

A rare morphologic variant of esophageal squamous cell carcinoma. Histologically, it is composed of closely packed cells with hyperchromatic nuclei and scant basophilic cytoplasm. It has a similar prognosis to the conventional squamous cell carcinoma of the esophagus. (WHO) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEsophageal basaloid carcinoma

Professional guidelines

PubMed

The importance of adjuvant treatment and primary anatomical site in head and neck basaloid squamous cell carcinoma survival: an analysis of the National Cancer Database.
Gootee J, Patel M, Aurit S, Silberstein P
Clin Transl Oncol 2020 Dec;22(12):2264-2274. Epub 2020 May 21 doi: 10.1007/s12094-020-02370-2. PMID: 32440914
Comparative Analysis of Clinical, Treatment, and Survival Characteristics of Basaloid and Squamous Cell Carcinoma of the Esophagus.
Salami A, Abbas AE, Petrov R, Jhala N, Bakhos CT
J Am Coll Surg 2018 Jun;226(6):1086-1092. Epub 2017 Nov 11 doi: 10.1016/j.jamcollsurg.2017.10.019. PMID: 29133264
Basaloid squamous cell carcinoma of the esophagus: assessment for high-risk human papillomavirus and related molecular markers.
Bellizzi AM, Woodford RL, Moskaluk CA, Jones DR, Kozower BD, Stelow EB
Am J Surg Pathol 2009 Nov;33(11):1608-14. doi: 10.1097/PAS.0b013e3181b46fd4. PMID: 19738459

Recent clinical studies

Diagnosis

A case of leptomeningeal carcinomatosis from esophageal basaloid carcinoma diagnosed by quantitative reverse transcription-polymerase chain reaction for carcinoembryonic antigen.
Okumura H, Natsugoe S, Yokomakura N, Mataki Y, Haraguchi Y, Sakita H, Mihara Y, Matsumoto M, Imamura S, Kuratsu J, Ishigami S, Takao S, Aikou T
J Gastroenterol 2005 Jan;40(1):87-93. doi: 10.1007/s00535-004-1498-3. PMID: 15692794

Prognosis

A case of leptomeningeal carcinomatosis from esophageal basaloid carcinoma diagnosed by quantitative reverse transcription-polymerase chain reaction for carcinoembryonic antigen.
Okumura H, Natsugoe S, Yokomakura N, Mataki Y, Haraguchi Y, Sakita H, Mihara Y, Matsumoto M, Imamura S, Kuratsu J, Ishigami S, Takao S, Aikou T
J Gastroenterol 2005 Jan;40(1):87-93. doi: 10.1007/s00535-004-1498-3. PMID: 15692794

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