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Eccrine dermal cylindroma

MedGen UID:
220995
•Concept ID:
C1305968
•
Neoplastic Process
Synonyms: Eccrine dermal cylindroma of skin; Spiegler's tumor
SNOMED CT: Eccrine dermal cylindroma (64773009); Eccrine dermal cylindroma of skin (274903001); Spiegler's tumor (274903001); Eccrine dermal cylindroma (274903001)

Recent clinical studies

Etiology

Expression of stem-cell markers (cytokeratin 15 and nestin) in primary adnexal neoplasms-clues to etiopathogenesis.
Mahalingam M, Srivastava A, Hoang MP
Am J Dermatopathol 2010 Dec;32(8):774-9. doi: 10.1097/DAD.0b013e3181dafd8c. PMID: 20700038
Isoantigens A, B, H in normal skin and tumors of the epidermal appendages.
England DM, Solie B, Winkelmann RK
Arch Pathol Lab Med 1979 Oct;103(11):586-90. PMID: 226027

Diagnosis

Cylindroma of head and neck: review of the literature and report of two rare cases.
Singh DD, Naujoks C, Depprich R, Schulte KW, Jankowiak F, Kübler NR, Handschel J
J Craniomaxillofac Surg 2013 Sep;41(6):516-21. Epub 2012 Dec 21 doi: 10.1016/j.jcms.2012.11.016. PMID: 23260808
Expression of stem-cell markers (cytokeratin 15 and nestin) in primary adnexal neoplasms-clues to etiopathogenesis.
Mahalingam M, Srivastava A, Hoang MP
Am J Dermatopathol 2010 Dec;32(8):774-9. doi: 10.1097/DAD.0b013e3181dafd8c. PMID: 20700038
Cylindroma (dermal analog tumor) of the breast: a comparison with cylindroma of the skin and adenoid cystic carcinoma of the breast.
Albores-Saavedra J, Heard SC, McLaren B, Kamino H, Witkiewicz AK
Am J Clin Pathol 2005 Jun;123(6):866-73. doi: 10.1309/CRWU-A3K0-MPQH-QC4W. PMID: 15899777
Dermal cylindroma and eccrine spiradenoma.
Lee MW, Kelly JW
Australas J Dermatol 1996 Feb;37(1):48-9. doi: 10.1111/j.1440-0960.1996.tb00995.x. PMID: 8936072
Benign dermal eccrine cylindroma. A pitfall in the cytologic diagnosis of adenoid cystic carcinoma.
Bondeson L, Lindholm K, Thorstenson S
Acta Cytol 1983 May-Jun;27(3):326-8. PMID: 6306974

Prognosis

Expression of stem-cell markers (cytokeratin 15 and nestin) in primary adnexal neoplasms-clues to etiopathogenesis.
Mahalingam M, Srivastava A, Hoang MP
Am J Dermatopathol 2010 Dec;32(8):774-9. doi: 10.1097/DAD.0b013e3181dafd8c. PMID: 20700038
Dermal eccrine cylindroma (turban tumour).
Irwin LR, Bainbridge LC, Reid CA, Piggot TA, Brown HG
Br J Plast Surg 1990 Nov;43(6):702-5. doi: 10.1016/0007-1226(90)90194-5. PMID: 2175228

Clinical prediction guides

Expression of stem-cell markers (cytokeratin 15 and nestin) in primary adnexal neoplasms-clues to etiopathogenesis.
Mahalingam M, Srivastava A, Hoang MP
Am J Dermatopathol 2010 Dec;32(8):774-9. doi: 10.1097/DAD.0b013e3181dafd8c. PMID: 20700038
Epithelial markers and differentiation in adnexal neoplasms of the skin: an immunohistochemical study including individual cytokeratins.
Demirkesen C, Hoede N, Moll R
J Cutan Pathol 1995 Dec;22(6):518-35. doi: 10.1111/j.1600-0560.1995.tb01147.x. PMID: 8835171
Malignant transformation of eccrine spiradenoma.
Cooper PH, Frierson HF Jr, Morrison AG
Arch Dermatol 1985 Nov;121(11):1445-8. PMID: 2996443

Recent systematic reviews

Cylindroma of head and neck: review of the literature and report of two rare cases.
Singh DD, Naujoks C, Depprich R, Schulte KW, Jankowiak F, Kübler NR, Handschel J
J Craniomaxillofac Surg 2013 Sep;41(6):516-21. Epub 2012 Dec 21 doi: 10.1016/j.jcms.2012.11.016. PMID: 23260808

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