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Acute apical abscess

MedGen UID:
713002
•Concept ID:
C1290646
•
Disease or Syndrome
Synonyms: Acute alveolar abscess; Acute dentoalveolar abscess; Acute periapical abscess
SNOMED CT: Acute apical abscess (109602002); Acute alveolar abscess (109602002); Acute dentoalveolar abscess (109602002); Acute periapical abscess (109602002)

Professional guidelines

PubMed

Evidence-based clinical practice guideline on antibiotic use for the urgent management of pulpal- and periapical-related dental pain and intraoral swelling: A report from the American Dental Association.
Lockhart PB, Tampi MP, Abt E, Aminoshariae A, Durkin MJ, Fouad AF, Gopal P, Hatten BW, Kennedy E, Lang MS, Patton LL, Paumier T, Suda KJ, Pilcher L, Urquhart O, O'Brien KK, Carrasco-Labra A
J Am Dent Assoc 2019 Nov;150(11):906-921.e12. doi: 10.1016/j.adaj.2019.08.020. PMID: 31668170Free PMC Article
Microbiology and treatment of acute apical abscesses.
Siqueira JF Jr, Rôças IN
Clin Microbiol Rev 2013 Apr;26(2):255-73. doi: 10.1128/CMR.00082-12. PMID: 23554416Free PMC Article
Emergency management of acute apical abscesses in the permanent dentition: a systematic review of the literature.
Matthews DC, Sutherland S, Basrani B
J Can Dent Assoc 2003 Nov;69(10):660. PMID: 14611715

Recent clinical studies

Etiology

Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults.
Cope AL, Francis N, Wood F, Thompson W, Chestnutt IG
Cochrane Database Syst Rev 2024 May 7;5(5):CD010136. doi: 10.1002/14651858.CD010136.pub4. PMID: 38712714Free PMC Article
Antibiotics for the urgent management of symptomatic irreversible pulpitis, symptomatic apical periodontitis, and localized acute apical abscess: Systematic review and meta-analysis-a report of the American Dental Association.
Tampi MP, Pilcher L, Urquhart O, Kennedy E, O'Brien KK, Lockhart PB, Abt E, Aminoshariae A, Durkin MJ, Fouad AF, Gopal P, Hatten BW, Lang MS, Patton LL, Paumier T, Suda KJ, Cho H, Carrasco-Labra A
J Am Dent Assoc 2019 Dec;150(12):e179-e216. doi: 10.1016/j.adaj.2019.09.011. PMID: 31761029Free PMC Article
Evidence-based clinical practice guideline on antibiotic use for the urgent management of pulpal- and periapical-related dental pain and intraoral swelling: A report from the American Dental Association.
Lockhart PB, Tampi MP, Abt E, Aminoshariae A, Durkin MJ, Fouad AF, Gopal P, Hatten BW, Kennedy E, Lang MS, Patton LL, Paumier T, Suda KJ, Pilcher L, Urquhart O, O'Brien KK, Carrasco-Labra A
J Am Dent Assoc 2019 Nov;150(11):906-921.e12. doi: 10.1016/j.adaj.2019.08.020. PMID: 31668170Free PMC Article
Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults.
Cope AL, Francis N, Wood F, Chestnutt IG
Cochrane Database Syst Rev 2018 Sep 27;9(9):CD010136. doi: 10.1002/14651858.CD010136.pub3. PMID: 30259968Free PMC Article
Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults.
Cope A, Francis N, Wood F, Mann MK, Chestnutt IG
Cochrane Database Syst Rev 2014 Jun 26;(6):CD010136. doi: 10.1002/14651858.CD010136.pub2. PMID: 24967571

Diagnosis

Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults.
Cope AL, Francis N, Wood F, Thompson W, Chestnutt IG
Cochrane Database Syst Rev 2024 May 7;5(5):CD010136. doi: 10.1002/14651858.CD010136.pub4. PMID: 38712714Free PMC Article
Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults.
Cope AL, Francis N, Wood F, Chestnutt IG
Cochrane Database Syst Rev 2018 Sep 27;9(9):CD010136. doi: 10.1002/14651858.CD010136.pub3. PMID: 30259968Free PMC Article
Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults.
Cope A, Francis N, Wood F, Mann MK, Chestnutt IG
Cochrane Database Syst Rev 2014 Jun 26;(6):CD010136. doi: 10.1002/14651858.CD010136.pub2. PMID: 24967571
Microbiology and treatment of acute apical abscesses.
Siqueira JF Jr, Rôças IN
Clin Microbiol Rev 2013 Apr;26(2):255-73. doi: 10.1128/CMR.00082-12. PMID: 23554416Free PMC Article
Dental caries and pulpal disease.
Zero DT, Zandona AF, Vail MM, Spolnik KJ
Dent Clin North Am 2011 Jan;55(1):29-46. doi: 10.1016/j.cden.2010.08.010. PMID: 21094717

Therapy

Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults.
Cope AL, Francis N, Wood F, Thompson W, Chestnutt IG
Cochrane Database Syst Rev 2024 May 7;5(5):CD010136. doi: 10.1002/14651858.CD010136.pub4. PMID: 38712714Free PMC Article
Antibiotics for the urgent management of symptomatic irreversible pulpitis, symptomatic apical periodontitis, and localized acute apical abscess: Systematic review and meta-analysis-a report of the American Dental Association.
Tampi MP, Pilcher L, Urquhart O, Kennedy E, O'Brien KK, Lockhart PB, Abt E, Aminoshariae A, Durkin MJ, Fouad AF, Gopal P, Hatten BW, Lang MS, Patton LL, Paumier T, Suda KJ, Cho H, Carrasco-Labra A
J Am Dent Assoc 2019 Dec;150(12):e179-e216. doi: 10.1016/j.adaj.2019.09.011. PMID: 31761029Free PMC Article
Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults.
Cope AL, Francis N, Wood F, Chestnutt IG
Cochrane Database Syst Rev 2018 Sep 27;9(9):CD010136. doi: 10.1002/14651858.CD010136.pub3. PMID: 30259968Free PMC Article
Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults.
Cope A, Francis N, Wood F, Mann MK, Chestnutt IG
Cochrane Database Syst Rev 2014 Jun 26;(6):CD010136. doi: 10.1002/14651858.CD010136.pub2. PMID: 24967571
Microbiology and treatment of acute apical abscesses.
Siqueira JF Jr, Rôças IN
Clin Microbiol Rev 2013 Apr;26(2):255-73. doi: 10.1128/CMR.00082-12. PMID: 23554416Free PMC Article

Prognosis

Medication-Related Osteonecrosis of the Jaw (MRONJ) Mistaken for Acute Apical Abscess.
Meshkin M, McDermott C, Pryles RL, Blicher B
Compend Contin Educ Dent 2024 May;45(5):248-251. PMID: 38900463
Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults.
Cope AL, Francis N, Wood F, Thompson W, Chestnutt IG
Cochrane Database Syst Rev 2024 May 7;5(5):CD010136. doi: 10.1002/14651858.CD010136.pub4. PMID: 38712714Free PMC Article
A prospective cohort study evaluating the outcome of root canal retreatment in symptomatic mandibular first molars with periapical lesions.
Serefoglu B, Miçooğulları Kurt S, Kandemir Demirci G, Kaval ME, Çalışkan MK
Int Endod J 2021 Dec;54(12):2173-2183. Epub 2021 Sep 24 doi: 10.1111/iej.13631. PMID: 34516682
The prescribing of antibiotics for endodontic infections by dentists in Turkey: a comprehensive survey.
Deniz-Sungur D, Aksel H, Karaismailoglu E, Sayin TC
Int Endod J 2020 Dec;53(12):1715-1727. Epub 2020 Sep 18 doi: 10.1111/iej.13390. PMID: 32805741
Treatment of an Acute Apical Abscess in a Patient With Autoimmune Hepatitis Taking Alendronate: A Case Report.
de Albuquerque MS, Rizuto AV, de Araújo Silva Tavares ÁF, Nascimento AS, de Souza Araújo PR, de Lima EA, Braz da Silva R
J Endod 2019 Dec;45(12):1550-1555. doi: 10.1016/j.joen.2019.09.010. PMID: 31757341

Clinical prediction guides

Evaluation of Serum Levels of Cytokines in Acute Apical Abscess: A Longitudinal Observational Study.
Palafox-Sánchez CA, Cruz A, Salazar-Camarena DC, Gascón LG, Cintra LTA, Muñoz-Valle JF, García-Arellano S, Estrela C, Menchaca-Tapia PA
J Endod 2023 Sep;49(9):1090-1098. Epub 2023 Jul 8 doi: 10.1016/j.joen.2023.07.001. PMID: 37423583
Endodontics Specialists' Practice during the Initial Outbreak of Coronavirus Disease 2019.
Nosrat A, Dianat O, Verma P, Yu P, Wu D, Fouad AF
J Endod 2022 Jan;48(1):102-108. Epub 2021 Oct 6 doi: 10.1016/j.joen.2021.09.015. PMID: 34626613Free PMC Article
Comparison between isolated and associated with codeine acetaminophen in pain control of acute apical abscess: a randomized clinical trial.
da Silva PB, Mendes AT, Cardoso MBF, da Rosa RA, do Nascimento AL, Pereira JR, Só MVR
Clin Oral Investig 2021 Mar;25(3):875-882. Epub 2020 Jul 10 doi: 10.1007/s00784-020-03374-6. PMID: 32651644
Characteristics of Endodontic Emergencies during Coronavirus Disease 2019 Outbreak in Wuhan.
Yu J, Zhang T, Zhao D, Haapasalo M, Shen Y
J Endod 2020 Jun;46(6):730-735. Epub 2020 Apr 10 doi: 10.1016/j.joen.2020.04.001. PMID: 32360053Free PMC Article
Potential role of TP63 in apical periodontitis development.
Souza LC, Crozeta BM, Guajardo L, Brasil da Costa FH, Sousa-Neto MD, Letra A, Silva RM
Int Endod J 2019 Sep;52(9):1344-1353. Epub 2019 May 20 doi: 10.1111/iej.13133. PMID: 31025362

Recent systematic reviews

Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults.
Cope AL, Francis N, Wood F, Thompson W, Chestnutt IG
Cochrane Database Syst Rev 2024 May 7;5(5):CD010136. doi: 10.1002/14651858.CD010136.pub4. PMID: 38712714Free PMC Article
Antibiotics for the urgent management of symptomatic irreversible pulpitis, symptomatic apical periodontitis, and localized acute apical abscess: Systematic review and meta-analysis-a report of the American Dental Association.
Tampi MP, Pilcher L, Urquhart O, Kennedy E, O'Brien KK, Lockhart PB, Abt E, Aminoshariae A, Durkin MJ, Fouad AF, Gopal P, Hatten BW, Lang MS, Patton LL, Paumier T, Suda KJ, Cho H, Carrasco-Labra A
J Am Dent Assoc 2019 Dec;150(12):e179-e216. doi: 10.1016/j.adaj.2019.09.011. PMID: 31761029Free PMC Article
Evidence-based clinical practice guideline on antibiotic use for the urgent management of pulpal- and periapical-related dental pain and intraoral swelling: A report from the American Dental Association.
Lockhart PB, Tampi MP, Abt E, Aminoshariae A, Durkin MJ, Fouad AF, Gopal P, Hatten BW, Kennedy E, Lang MS, Patton LL, Paumier T, Suda KJ, Pilcher L, Urquhart O, O'Brien KK, Carrasco-Labra A
J Am Dent Assoc 2019 Nov;150(11):906-921.e12. doi: 10.1016/j.adaj.2019.08.020. PMID: 31668170Free PMC Article
Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults.
Cope AL, Francis N, Wood F, Chestnutt IG
Cochrane Database Syst Rev 2018 Sep 27;9(9):CD010136. doi: 10.1002/14651858.CD010136.pub3. PMID: 30259968Free PMC Article
Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults.
Cope A, Francis N, Wood F, Mann MK, Chestnutt IG
Cochrane Database Syst Rev 2014 Jun 26;(6):CD010136. doi: 10.1002/14651858.CD010136.pub2. PMID: 24967571

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