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Drug-induced Stevens-Johnson syndrome

MedGen UID:
698245
•Concept ID:
C1274933
•
Disease or Syndrome
Synonyms: Drug Induced Stevens Johnson Syndrome; Drug-Induced Stevens Johnson Syndrome; Drug-Induced Stevens-Johnson Syndrome; Drug-Induced Stevens-Johnson Syndromes; Stevens-Johnson Syndrome, Drug-Induced; Stevens-Johnson Syndromes, Drug-Induced
SNOMED CT: Drug-induced Stevens-Johnson syndrome (403609001); Stevens-Johnson syndrome caused by drug (403609001)

Professional guidelines

PubMed

Management of Drug-Induced Epidermal Necrolysis (DEN) in Pediatric Patients: Moving from Drug-Induced Stevens-Johnson Syndrome, Overlap and Toxic Epidermal Necrolysis to a Single Unifying Diagnosis of DEN.
Ramien ML, Mansour D, Shear NH
Paediatr Drugs 2022 Jul;24(4):307-319. Epub 2022 Jun 9 doi: 10.1007/s40272-022-00515-0. PMID: 35676614
Clinical features, outcomes and treatment in children with drug induced Stevens-Johnson syndrome and toxic epidermal necrolysis.
Liotti L, Caimmi S, Bottau P, Bernardini R, Cardinale F, Saretta F, Mori F, Crisafulli G, Franceschini F, Caffarelli C
Acta Biomed 2019 Jan 29;90(3-S):52-60. doi: 10.23750/abm.v90i3-S.8165. PMID: 30830062Free PMC Article
A systematic review of treatment of drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in children.
Del Pozzo-Magana BR, Lazo-Langner A, Carleton B, Castro-Pastrana LI, Rieder MJ
J Popul Ther Clin Pharmacol 2011;18:e121-33. Epub 2011 Mar 21 PMID: 21467603

Recent clinical studies

Therapy

Drug-induced Stevens-Johnson syndrome in Post traumatic facial injury.
Samar A, Sahana GN, Deepak P, Nagaral JV, Saranyaa M
Indian J Pharmacol 2024 Jan 1;56(1):58-60. Epub 2024 Mar 8 doi: 10.4103/ijp.ijp_485_23. PMID: 38454591Free PMC Article
A Case of Drug-Induced Stevens-Johnson Syndrome.
Lyon DR, Akinboboye O, Jain PV, Jha P
WMJ 2022 Oct;121(3):E63-E65. PMID: 36301663
Drug-induced Stevens-Johnson syndrome: a disproportionality analysis from the pharmacovigilance database of the World Health Organization.
Zheng Y, Zhou W, Guo X, Chi L, Chen C, Guo Z, Liang J, Wei L, Chen X, Ye X, He J
Expert Opin Drug Saf 2022 Aug;21(8):1127-1133. Epub 2022 Mar 17 doi: 10.1080/14740338.2022.2045946. PMID: 35196201
Drug-induced Stevens-Johnson syndrome in Indian population: A multicentric retrospective analysis.
Hirapara HN, Patel TK, Barvaliya MJ, Tripathi C
Niger J Clin Pract 2017 Aug;20(8):978-983. doi: 10.4103/njcp.njcp_122_16. PMID: 28891542
Mycoplasma pneumoniae-induced rash and mucositis as a syndrome distinct from Stevens-Johnson syndrome and erythema multiforme: a systematic review.
Canavan TN, Mathes EF, Frieden I, Shinkai K
J Am Acad Dermatol 2015 Feb;72(2):239-45. doi: 10.1016/j.jaad.2014.06.026. PMID: 25592340

Prognosis

Stevens-Johnson syndrome-toxic epidermal necrolysis overlap in a patient taking quetiapine and famotidine: a case report.
Su CS, Kao CL
J Med Case Rep 2024 Jul 28;18(1):344. doi: 10.1186/s13256-024-04629-6. PMID: 39068499Free PMC Article
A Case of Drug-Induced Stevens-Johnson Syndrome.
Lyon DR, Akinboboye O, Jain PV, Jha P
WMJ 2022 Oct;121(3):E63-E65. PMID: 36301663
Drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in children: 20 years study in a tertiary care hospital.
Techasatian L, Panombualert S, Uppala R, Jetsrisuparb C
World J Pediatr 2017 Jun;13(3):255-260. Epub 2016 Sep 20 doi: 10.1007/s12519-016-0057-3. PMID: 27650525
Mycoplasma pneumoniae-induced rash and mucositis as a syndrome distinct from Stevens-Johnson syndrome and erythema multiforme: a systematic review.
Canavan TN, Mathes EF, Frieden I, Shinkai K
J Am Acad Dermatol 2015 Feb;72(2):239-45. doi: 10.1016/j.jaad.2014.06.026. PMID: 25592340
Association of HLA-B*1502 and *1511 allele with antiepileptic drug-induced Stevens-Johnson syndrome in central China.
Sun D, Yu CH, Liu ZS, He XL, Hu JS, Wu GF, Mao B, Wu SH, Xiang HH
J Huazhong Univ Sci Technolog Med Sci 2014 Feb;34(1):146-150. Epub 2014 Feb 6 doi: 10.1007/s11596-014-1247-7. PMID: 24496695

Clinical prediction guides

Drug-induced Stevens-Johnson syndrome: a disproportionality analysis from the pharmacovigilance database of the World Health Organization.
Zheng Y, Zhou W, Guo X, Chi L, Chen C, Guo Z, Liang J, Wei L, Chen X, Ye X, He J
Expert Opin Drug Saf 2022 Aug;21(8):1127-1133. Epub 2022 Mar 17 doi: 10.1080/14740338.2022.2045946. PMID: 35196201
Agreement Among Different Scales for Causality Assessment in Drug-Induced Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.
Sivagourounadin K, Rajendran P, Selvarajan S, Ganesapandian M
Curr Drug Saf 2022;17(1):40-46. doi: 10.2174/1574886316666210611160123. PMID: 34126908
Drug-induced Stevens-Johnson syndrome in Indian population: A multicentric retrospective analysis.
Hirapara HN, Patel TK, Barvaliya MJ, Tripathi C
Niger J Clin Pract 2017 Aug;20(8):978-983. doi: 10.4103/njcp.njcp_122_16. PMID: 28891542
A systematic review of the drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Indian population.
Patel TK, Barvaliya MJ, Sharma D, Tripathi C
Indian J Dermatol Venereol Leprol 2013 May-Jun;79(3):389-98. doi: 10.4103/0378-6323.110749. PMID: 23619444
A systematic review of treatment of drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in children.
Del Pozzo-Magana BR, Lazo-Langner A, Carleton B, Castro-Pastrana LI, Rieder MJ
J Popul Ther Clin Pharmacol 2011;18:e121-33. Epub 2011 Mar 21 PMID: 21467603

Recent systematic reviews

Unraveling the genetic link: an umbrella review on HLA-B*15:02 and antiepileptic drug-induced Stevens-Johnson syndrome/toxic epidermal necrolysis.
Tham KM, Yek JJL, Liu CWY
Pharmacogenet Genomics 2024 Jul 1;34(5):154-165. Epub 2024 Mar 22 doi: 10.1097/FPC.0000000000000531. PMID: 38527170
Mycoplasma pneumoniae-induced rash and mucositis as a syndrome distinct from Stevens-Johnson syndrome and erythema multiforme: a systematic review.
Canavan TN, Mathes EF, Frieden I, Shinkai K
J Am Acad Dermatol 2015 Feb;72(2):239-45. doi: 10.1016/j.jaad.2014.06.026. PMID: 25592340
A systematic review of the drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Indian population.
Patel TK, Barvaliya MJ, Sharma D, Tripathi C
Indian J Dermatol Venereol Leprol 2013 May-Jun;79(3):389-98. doi: 10.4103/0378-6323.110749. PMID: 23619444
A systematic review of treatment of drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in children.
Del Pozzo-Magana BR, Lazo-Langner A, Carleton B, Castro-Pastrana LI, Rieder MJ
J Popul Ther Clin Pharmacol 2011;18:e121-33. Epub 2011 Mar 21 PMID: 21467603

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