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Fatal infectious mononucleosis

MedGen UID:
688835
•Concept ID:
C1264624
•
Disease or Syndrome
SNOMED CT: Fatal infectious mononucleosis (128872002)

Recent clinical studies

Etiology

The apoptosis modulating role of SAP (SLAM associated protein) contributes to the symptomatology of the X linked lymphoproliferative disease.
Nagy N, Matskova L, Hellman U, Klein G, Klein E
Cell Cycle 2009 Oct 1;8(19):3086-90. Epub 2009 Oct 27 doi: 10.4161/cc.8.19.9636. PMID: 19738428
The pathology of NK-cell lymphomas and leukemias.
Nava VE, Jaffe ES
Adv Anat Pathol 2005 Jan;12(1):27-34. doi: 10.1097/01.pap.0000151318.34752.80. PMID: 15614162
The molecular characterization of fatal infectious mononucleosis.
Wick MJ, Woronzoff-Dashkoff KP, McGlennen RC
Am J Clin Pathol 2002 Apr;117(4):582-8. doi: 10.1309/b3wh-qwby-yv61-ce46. PMID: 11939733
Evaluation of families wherein a single male manifests a phenotype of X-linked lymphoproliferative disease (XLP).
Grierson HL, Skare J, Church J, Silberman T, Davis JR, Kobrinsky N, McGregor R, Israels S, McCarty J, Andrews LG
Am J Med Genet 1993 Sep 15;47(4):458-63. doi: 10.1002/ajmg.1320470404. PMID: 8256804
Immunopathology of the X-linked lymphoproliferative syndrome.
Purtilo DT
Haematol Blood Transfus 1981;26:207-14. doi: 10.1007/978-3-642-67984-1_34. PMID: 6274747

Diagnosis

The pathology of NK-cell lymphomas and leukemias.
Nava VE, Jaffe ES
Adv Anat Pathol 2005 Jan;12(1):27-34. doi: 10.1097/01.pap.0000151318.34752.80. PMID: 15614162
Benign and malignant Epstein-Barr virus-associated B-cell lymphoproliferative diseases.
Cohen JI
Semin Hematol 2003 Apr;40(2):116-23. doi: 10.1053/shem.2003.50018. PMID: 12704588
Hepatitis in fatal infectious mononucleosis.
Markin RS, Linder J, Zuerlein K, Mroczek E, Grierson HL, Brichacek B, Purtilo DT
Gastroenterology 1987 Dec;93(6):1210-7. doi: 10.1016/0016-5085(87)90246-0. PMID: 3678738
Fatal infectious mononucleosis.
Ozsoylu S, Koldaş M, Gürgey A, Tel N
Turk J Pediatr 1976 Jul-Oct;18(3-4):116-9. PMID: 1052592
Fatal infectious mononucleosis: a critical review.
Penman HG
J Clin Pathol 1970 Dec;23(9):765-71. doi: 10.1136/jcp.23.9.765. PMID: 4926819Free PMC Article

Therapy

Fatal infectious mononucleosis with evidence suggestive of the development of B cell lymphoma.
Hiroshima K, Iyoda A, Isobe K, Ishii G, Toyozaki T, Shibuya K, Shimamura F, Haga Y, Okimoto Y, Horie H, Harigaya K, Ohwada H
Pathol Int 2003 Sep;53(9):642-8. doi: 10.1046/j.1440-1827.2003.01522.x. PMID: 14507324
Fatal infectious mononucleosis: a severe complication in the treatment of Crohn's disease with azathioprine.
Posthuma EF, Westendorp RG, van der Sluys Veer A, Kluin-Nelemans JC, Kluin PM, Lamers CB
Gut 1995 Feb;36(2):311-3. doi: 10.1136/gut.36.2.311. PMID: 7883236Free PMC Article
Immunovirological studies of fatal infectious mononucleosis in a patient with X-linked lymphoproliferative syndrome treated with intravenous immunoglobulin and interferon-alpha.
Okano M, Pirruccello SJ, Grierson HL, Johnson DR, Thiele GM, Purtilo DT
Clin Immunol Immunopathol 1990 Mar;54(3):410-8. doi: 10.1016/0090-1229(90)90054-t. PMID: 2302842
Prevention and treatment of Epstein-Barr virus (EBV)-associated lymphoproliferative diseases in immune deficient patients.
Purtilo DT
AIDS Res 1986 Dec;2 Suppl 1:S177-81. PMID: 2435295
Immunopathology of the X-linked lymphoproliferative syndrome.
Purtilo DT
Haematol Blood Transfus 1981;26:207-14. doi: 10.1007/978-3-642-67984-1_34. PMID: 6274747

Prognosis

Systemic type Epstein-Barr virus-related lymphoproliferative diseases in children and young adults: challenges for pediatric hemato-oncologists and infectious disease specialists.
Imashuku S
Pediatr Hematol Oncol 2007 Dec;24(8):563-8. doi: 10.1080/08880010701640499. PMID: 18092246
Fatal infectious mononucleosis with evidence suggestive of the development of B cell lymphoma.
Hiroshima K, Iyoda A, Isobe K, Ishii G, Toyozaki T, Shibuya K, Shimamura F, Haga Y, Okimoto Y, Horie H, Harigaya K, Ohwada H
Pathol Int 2003 Sep;53(9):642-8. doi: 10.1046/j.1440-1827.2003.01522.x. PMID: 14507324
Benign and malignant Epstein-Barr virus-associated B-cell lymphoproliferative diseases.
Cohen JI
Semin Hematol 2003 Apr;40(2):116-23. doi: 10.1053/shem.2003.50018. PMID: 12704588
X-linked lymphoproliferative disease is caused by deficiency of a novel SH2 domain-containing signal transduction adaptor protein.
Schuster V, Kreth HW
Immunol Rev 2000 Dec;178:21-8. doi: 10.1034/j.1600-065x.2000.17819.x. PMID: 11213803
Malignant lymphoma in the X-linked lymphoproliferative syndrome.
Harrington DS, Weisenburger DD, Purtilo DT
Cancer 1987 Apr 15;59(8):1419-29. doi: 10.1002/1097-0142(19870415)59:8<1419::aid-cncr2820590807>3.0.co;2-p. PMID: 3815312

Clinical prediction guides

Fatal infectious mononucleosis with evidence suggestive of the development of B cell lymphoma.
Hiroshima K, Iyoda A, Isobe K, Ishii G, Toyozaki T, Shibuya K, Shimamura F, Haga Y, Okimoto Y, Horie H, Harigaya K, Ohwada H
Pathol Int 2003 Sep;53(9):642-8. doi: 10.1046/j.1440-1827.2003.01522.x. PMID: 14507324
The molecular characterization of fatal infectious mononucleosis.
Wick MJ, Woronzoff-Dashkoff KP, McGlennen RC
Am J Clin Pathol 2002 Apr;117(4):582-8. doi: 10.1309/b3wh-qwby-yv61-ce46. PMID: 11939733
Malignant lymphoma in the X-linked lymphoproliferative syndrome.
Harrington DS, Weisenburger DD, Purtilo DT
Cancer 1987 Apr 15;59(8):1419-29. doi: 10.1002/1097-0142(19870415)59:8<1419::aid-cncr2820590807>3.0.co;2-p. PMID: 3815312
Thymic lesions in fatal infectious mononucleosis.
Mroczek EC, Seemayer TA, Grierson HL, Markin RS, Linder J, Brichacek B, Purtilo DT
Clin Immunol Immunopathol 1987 May;43(2):243-55. doi: 10.1016/0090-1229(87)90132-2. PMID: 3568458
X-linked lymphoproliferative syndrome registry report.
Hamilton JK, Paquin LA, Sullivan JL, Maurer HS, Cruzi FG, Provisor AJ, Steuber CP, Hawkins E, Yawn D, Cornet JA, Clausen K, Finkelstein GZ, Landing B, Grunnet M, Purtilo DT
J Pediatr 1980 Apr;96(4):669-73. doi: 10.1016/s0022-3476(80)80735-9. PMID: 7188959

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