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Pseudomembranous Colitis

MedGen UID:
263446
•Concept ID:
C1257843
•
Disease or Syndrome
Synonym: Colitis, Pseudomembranous

Professional guidelines

PubMed

Management of Clostridioides difficile Infection: Diagnosis, Treatment, and Future Perspectives.
Cymbal M, Chatterjee A, Baggott B, Auron M
Am J Med 2024 Jul;137(7):571-576. Epub 2024 Mar 18 doi: 10.1016/j.amjmed.2024.03.024. PMID: 38508330
Clostridioides difficile Infection: Update on Management.
Mounsey A, Lacy Smith K, Reddy VC, Nickolich S
Am Fam Physician 2020 Feb 1;101(3):168-175. PMID: 32003951
The Differential Diagnosis of Acute Colitis: Clues to a Specific Diagnosis.
Jessurun J
Surg Pathol Clin 2017 Dec;10(4):863-885. doi: 10.1016/j.path.2017.07.008. PMID: 29103537

Recent clinical studies

Etiology

Clostridioides difficile Infection: Update on Management.
Mounsey A, Lacy Smith K, Reddy VC, Nickolich S
Am Fam Physician 2020 Feb 1;101(3):168-175. PMID: 32003951
Faecal microbiota transplantation: a regulatory hurdle?
Verbeke F, Janssens Y, Wynendaele E, De Spiegeleer B
BMC Gastroenterol 2017 Nov 28;17(1):128. doi: 10.1186/s12876-017-0687-5. PMID: 29179687Free PMC Article
Pseudomembranous colitis.
Farooq PD, Urrunaga NH, Tang DM, von Rosenvinge EC
Dis Mon 2015 May;61(5):181-206. Epub 2015 Mar 11 doi: 10.1016/j.disamonth.2015.01.006. PMID: 25769243Free PMC Article
Postoperative fever.
Dionigi R, Dionigi G, Rovera F, Boni L
Surg Infect (Larchmt) 2006;7 Suppl 2:S17-20. doi: 10.1089/sur.2006.7.s2-17. PMID: 16895496
Clostridium difficile infection.
Gröschel DH
Crit Rev Clin Lab Sci 1996;33(3):203-45. doi: 10.3109/10408369609083061. PMID: 8828001

Diagnosis

Management of Clostridioides difficile Infection: Diagnosis, Treatment, and Future Perspectives.
Cymbal M, Chatterjee A, Baggott B, Auron M
Am J Med 2024 Jul;137(7):571-576. Epub 2024 Mar 18 doi: 10.1016/j.amjmed.2024.03.024. PMID: 38508330
Clostridioides difficile Infection: Update on Management.
Mounsey A, Lacy Smith K, Reddy VC, Nickolich S
Am Fam Physician 2020 Feb 1;101(3):168-175. PMID: 32003951
The Differential Diagnosis of Acute Colitis: Clues to a Specific Diagnosis.
Jessurun J
Surg Pathol Clin 2017 Dec;10(4):863-885. doi: 10.1016/j.path.2017.07.008. PMID: 29103537
Clostridium difficile infection.
Alcalá Hernández L, Reigadas Ramírez E, Bouza Santiago E
Med Clin (Barc) 2017 May 23;148(10):456-463. Epub 2017 Apr 8 doi: 10.1016/j.medcli.2017.01.033. PMID: 28396132
Pseudomembranous colitis.
Farooq PD, Urrunaga NH, Tang DM, von Rosenvinge EC
Dis Mon 2015 May;61(5):181-206. Epub 2015 Mar 11 doi: 10.1016/j.disamonth.2015.01.006. PMID: 25769243Free PMC Article

Therapy

Clostridioides Difficile: A Concise Review of Best Practices and Updates.
Yakout A, Bi Y, Harris DM
J Prim Care Community Health 2024 Jan-Dec;15:21501319241249645. doi: 10.1177/21501319241249645. PMID: 38726585Free PMC Article
Management of Clostridioides difficile Infection: Diagnosis, Treatment, and Future Perspectives.
Cymbal M, Chatterjee A, Baggott B, Auron M
Am J Med 2024 Jul;137(7):571-576. Epub 2024 Mar 18 doi: 10.1016/j.amjmed.2024.03.024. PMID: 38508330
Phentermine-Associated Pseudomembranous Colitis.
Gollol Raju NS, Jayananda S, Ali E, Harvin G
Am J Ther 2021 Jul-Aug 01;28(4):e492-e493. doi: 10.1097/MJT.0000000000001068. PMID: 34228655
Clostridium difficile colitis: A clinical review.
Ong GK, Reidy TJ, Huk MD, Lane FR
Am J Surg 2017 Mar;213(3):565-571. Epub 2017 Jan 3 doi: 10.1016/j.amjsurg.2016.10.035. PMID: 28131326
Pseudomembranous colitis.
Price AB, Davies DR
J Clin Pathol 1977 Jan;30(1):1-12. doi: 10.1136/jcp.30.1.1. PMID: 838865Free PMC Article

Prognosis

Clostridium difficile infection.
Alcalá Hernández L, Reigadas Ramírez E, Bouza Santiago E
Med Clin (Barc) 2017 May 23;148(10):456-463. Epub 2017 Apr 8 doi: 10.1016/j.medcli.2017.01.033. PMID: 28396132
Pseudomembranous colitis.
Farooq PD, Urrunaga NH, Tang DM, von Rosenvinge EC
Dis Mon 2015 May;61(5):181-206. Epub 2015 Mar 11 doi: 10.1016/j.disamonth.2015.01.006. PMID: 25769243Free PMC Article
Host recognition of Clostridium difficile and the innate immune response.
Cowardin CA, Petri WA Jr
Anaerobe 2014 Dec;30:205-9. Epub 2014 Sep 16 doi: 10.1016/j.anaerobe.2014.08.014. PMID: 25223264Free PMC Article
Intra-abdominal manifestations of Henoch-Schönlein purpura.
Choong CK, Beasley SW
J Paediatr Child Health 1998 Oct;34(5):405-9. doi: 10.1046/j.1440-1754.1998.00263.x. PMID: 9767498
Antibiotic-induced colitis.
Devenyi AG
Semin Pediatr Surg 1995 Nov;4(4):215-20. PMID: 8548209

Clinical prediction guides

Glucosyltransferase-dependent and independent effects of Clostridioides difficile toxins during infection.
Peritore-Galve FC, Shupe JA, Cave RJ, Childress KO, Washington MK, Kuehne SA, Lacy DB
PLoS Pathog 2022 Feb;18(2):e1010323. Epub 2022 Feb 17 doi: 10.1371/journal.ppat.1010323. PMID: 35176123Free PMC Article
Tests for the diagnosis of Clostridium difficile infection: the next generation.
Carroll KC
Anaerobe 2011 Aug;17(4):170-4. Epub 2011 Mar 3 doi: 10.1016/j.anaerobe.2011.01.002. PMID: 21376826
Clostridium difficile infection.
Gröschel DH
Crit Rev Clin Lab Sci 1996;33(3):203-45. doi: 10.3109/10408369609083061. PMID: 8828001
Antibiotic-induced colitis.
Devenyi AG
Semin Pediatr Surg 1995 Nov;4(4):215-20. PMID: 8548209
Metronidazole (Flagyl IV, Searle).
Stranz MH, Bradley WE
Drug Intell Clin Pharm 1981 Nov;15(11):838-46. doi: 10.1177/106002808101501101. PMID: 7028437

Recent systematic reviews

Association of Gastric Acid Suppression With Recurrent Clostridium difficile Infection: A Systematic Review and Meta-analysis.
Tariq R, Singh S, Gupta A, Pardi DS, Khanna S
JAMA Intern Med 2017 Jun 1;177(6):784-791. doi: 10.1001/jamainternmed.2017.0212. PMID: 28346595Free PMC Article
Antimicrobial prophylaxis for colorectal surgery.
Nelson RL, Gladman E, Barbateskovic M
Cochrane Database Syst Rev 2014 May 9;2014(5):CD001181. doi: 10.1002/14651858.CD001181.pub4. PMID: 24817514Free PMC Article
Systematic review: faecal transplantation for the treatment of Clostridium difficile-associated disease.
Guo B, Harstall C, Louie T, Veldhuyzen van Zanten S, Dieleman LA
Aliment Pharmacol Ther 2012 Apr;35(8):865-75. Epub 2012 Feb 23 doi: 10.1111/j.1365-2036.2012.05033.x. PMID: 22360412
Systematic review of intestinal microbiota transplantation (fecal bacteriotherapy) for recurrent Clostridium difficile infection.
Gough E, Shaikh H, Manges AR
Clin Infect Dis 2011 Nov;53(10):994-1002. doi: 10.1093/cid/cir632. PMID: 22002980
Antimicrobial prophylaxis for colorectal surgery.
Nelson RL, Glenny AM, Song F
Cochrane Database Syst Rev 2009 Jan 21;(1):CD001181. doi: 10.1002/14651858.CD001181.pub3. PMID: 19160191

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