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Kallikrein hypertension

MedGen UID:
257936
•Concept ID:
C1171349
•
Disease or Syndrome
Synonym: Kallikrein attenuated hypertension
 
Monarch Initiative: MONDO:0023530

Professional guidelines

PubMed

Long-term Prophylaxis with Androgens in the management of Hereditary Angioedema (HAE) in emerging countries.
Guo Y, Zhang H, Lai H, Wang H, Chong-Neto HJ, Valle SOR, Zhu R
Orphanet J Rare Dis 2022 Nov 2;17(1):399. doi: 10.1186/s13023-022-02536-x. PMID: 36324138Free PMC Article
Hematoma Expansion: Clinical and Molecular Predictors and Corresponding Pharmacological Treatment.
Wang G, Zhang J
Curr Drug Targets 2017;18(12):1367-1376. doi: 10.2174/1389450117666160712092224. PMID: 27411712
Novel potential treatment modalities for ocular hypertension: focus on angiotensin and bradykinin system axes.
Sharif NA
J Ocul Pharmacol Ther 2015 Apr;31(3):131-45. Epub 2015 Jan 19 doi: 10.1089/jop.2014.0114. PMID: 25599263

Recent clinical studies

Etiology

PRESTO: A Phase III, Open-Label Study of Intensification of Androgen Blockade in Patients With High-Risk Biochemically Relapsed Castration-Sensitive Prostate Cancer (AFT-19).
Aggarwal R, Heller G, Hillman DW, Xiao H, Picus J, Taplin ME, Dorff T, Appleman L, Weckstein D, Patnaik A, Bryce A, Shevrin D, Mohler J, Anderson D, Rao A, Tagawa S, Tan A, Halabi S, Dooley K, O'Brien P, Chen R, Ryan CJ, Eggener SE, Morris MJ; EORTC-55994 Study Group
J Clin Oncol 2024 Apr 1;42(10):1114-1123. Epub 2024 Jan 23 doi: 10.1200/JCO.23.01157. PMID: 38261983
Novel risk genes and mechanisms implicated by exome sequencing of 2572 individuals with pulmonary arterial hypertension.
Zhu N, Pauciulo MW, Welch CL, Lutz KA, Coleman AW, Gonzaga-Jauregui C, Wang J, Grimes JM, Martin LJ, He H; PAH Biobank Enrolling Centers’ Investigators, Shen Y, Chung WK, Nichols WC
Genome Med 2019 Nov 14;11(1):69. doi: 10.1186/s13073-019-0685-z. PMID: 31727138Free PMC Article
Hypotensive Snake Venom Components-A Mini-Review.
Péterfi O, Boda F, Szabó Z, Ferencz E, Bába L
Molecules 2019 Jul 31;24(15) doi: 10.3390/molecules24152778. PMID: 31370142Free PMC Article
Darolutamide in Nonmetastatic, Castration-Resistant Prostate Cancer.
Fizazi K, Shore N, Tammela TL, Ulys A, Vjaters E, Polyakov S, Jievaltas M, Luz M, Alekseev B, Kuss I, Kappeler C, Snapir A, Sarapohja T, Smith MR; ARAMIS Investigators
N Engl J Med 2019 Mar 28;380(13):1235-1246. Epub 2019 Feb 14 doi: 10.1056/NEJMoa1815671. PMID: 30763142
Prediction of preeclampsia.
Myatt L, Miodovnik M
Semin Perinatol 1999 Feb;23(1):45-57. doi: 10.1016/s0146-0005(99)80059-7. PMID: 10102170

Diagnosis

PRESTO: A Phase III, Open-Label Study of Intensification of Androgen Blockade in Patients With High-Risk Biochemically Relapsed Castration-Sensitive Prostate Cancer (AFT-19).
Aggarwal R, Heller G, Hillman DW, Xiao H, Picus J, Taplin ME, Dorff T, Appleman L, Weckstein D, Patnaik A, Bryce A, Shevrin D, Mohler J, Anderson D, Rao A, Tagawa S, Tan A, Halabi S, Dooley K, O'Brien P, Chen R, Ryan CJ, Eggener SE, Morris MJ; EORTC-55994 Study Group
J Clin Oncol 2024 Apr 1;42(10):1114-1123. Epub 2024 Jan 23 doi: 10.1200/JCO.23.01157. PMID: 38261983
Novel risk genes and mechanisms implicated by exome sequencing of 2572 individuals with pulmonary arterial hypertension.
Zhu N, Pauciulo MW, Welch CL, Lutz KA, Coleman AW, Gonzaga-Jauregui C, Wang J, Grimes JM, Martin LJ, He H; PAH Biobank Enrolling Centers’ Investigators, Shen Y, Chung WK, Nichols WC
Genome Med 2019 Nov 14;11(1):69. doi: 10.1186/s13073-019-0685-z. PMID: 31727138Free PMC Article
Familial hyperaldosteronism.
Stowasser M, Gordon RD
J Steroid Biochem Mol Biol 2001 Sep;78(3):215-29. doi: 10.1016/s0960-0760(01)00097-8. PMID: 11595502
Prediction of preeclampsia.
Myatt L, Miodovnik M
Semin Perinatol 1999 Feb;23(1):45-57. doi: 10.1016/s0146-0005(99)80059-7. PMID: 10102170
Renal kallikrein-kinin system.
Scicli AG, Carretero OA
Kidney Int 1986 Jan;29(1):120-30. doi: 10.1038/ki.1986.14. PMID: 3007849

Therapy

PRESTO: A Phase III, Open-Label Study of Intensification of Androgen Blockade in Patients With High-Risk Biochemically Relapsed Castration-Sensitive Prostate Cancer (AFT-19).
Aggarwal R, Heller G, Hillman DW, Xiao H, Picus J, Taplin ME, Dorff T, Appleman L, Weckstein D, Patnaik A, Bryce A, Shevrin D, Mohler J, Anderson D, Rao A, Tagawa S, Tan A, Halabi S, Dooley K, O'Brien P, Chen R, Ryan CJ, Eggener SE, Morris MJ; EORTC-55994 Study Group
J Clin Oncol 2024 Apr 1;42(10):1114-1123. Epub 2024 Jan 23 doi: 10.1200/JCO.23.01157. PMID: 38261983
Hypotensive Snake Venom Components-A Mini-Review.
Péterfi O, Boda F, Szabó Z, Ferencz E, Bába L
Molecules 2019 Jul 31;24(15) doi: 10.3390/molecules24152778. PMID: 31370142Free PMC Article
Darolutamide in Nonmetastatic, Castration-Resistant Prostate Cancer.
Fizazi K, Shore N, Tammela TL, Ulys A, Vjaters E, Polyakov S, Jievaltas M, Luz M, Alekseev B, Kuss I, Kappeler C, Snapir A, Sarapohja T, Smith MR; ARAMIS Investigators
N Engl J Med 2019 Mar 28;380(13):1235-1246. Epub 2019 Feb 14 doi: 10.1056/NEJMoa1815671. PMID: 30763142
Tissue kallikrein-kinin therapy in hypertension and organ damage.
Chao J, Bledsoe G, Chao L
Prog Drug Res 2014;69:37-57. doi: 10.1007/978-3-319-06683-7_3. PMID: 25130039
Familial hyperaldosteronism.
Stowasser M, Gordon RD
J Steroid Biochem Mol Biol 2001 Sep;78(3):215-29. doi: 10.1016/s0960-0760(01)00097-8. PMID: 11595502

Prognosis

PRESTO: A Phase III, Open-Label Study of Intensification of Androgen Blockade in Patients With High-Risk Biochemically Relapsed Castration-Sensitive Prostate Cancer (AFT-19).
Aggarwal R, Heller G, Hillman DW, Xiao H, Picus J, Taplin ME, Dorff T, Appleman L, Weckstein D, Patnaik A, Bryce A, Shevrin D, Mohler J, Anderson D, Rao A, Tagawa S, Tan A, Halabi S, Dooley K, O'Brien P, Chen R, Ryan CJ, Eggener SE, Morris MJ; EORTC-55994 Study Group
J Clin Oncol 2024 Apr 1;42(10):1114-1123. Epub 2024 Jan 23 doi: 10.1200/JCO.23.01157. PMID: 38261983
Identification of protein biomarkers associated with congenital diaphragmatic hernia in human amniotic fluid.
Bhutada S, Tran-Lundmark K, Kramer B, Conner P, Lowry AM, Blackstone E, Frenckner B, Mesas-Burgos C, Apte SS
Sci Rep 2023 Sep 19;13(1):15483. doi: 10.1038/s41598-023-42576-2. PMID: 37726509Free PMC Article
Hematoma Expansion: Clinical and Molecular Predictors and Corresponding Pharmacological Treatment.
Wang G, Zhang J
Curr Drug Targets 2017;18(12):1367-1376. doi: 10.2174/1389450117666160712092224. PMID: 27411712
Protective Role of Kallistatin in Vascular and Organ Injury.
Chao J, Bledsoe G, Chao L
Hypertension 2016 Sep;68(3):533-41. Epub 2016 Jul 18 doi: 10.1161/HYPERTENSIONAHA.116.07861. PMID: 27432868Free PMC Article
Prediction of preeclampsia.
Myatt L, Miodovnik M
Semin Perinatol 1999 Feb;23(1):45-57. doi: 10.1016/s0146-0005(99)80059-7. PMID: 10102170

Clinical prediction guides

Identification of protein biomarkers associated with congenital diaphragmatic hernia in human amniotic fluid.
Bhutada S, Tran-Lundmark K, Kramer B, Conner P, Lowry AM, Blackstone E, Frenckner B, Mesas-Burgos C, Apte SS
Sci Rep 2023 Sep 19;13(1):15483. doi: 10.1038/s41598-023-42576-2. PMID: 37726509Free PMC Article
Hematoma Expansion: Clinical and Molecular Predictors and Corresponding Pharmacological Treatment.
Wang G, Zhang J
Curr Drug Targets 2017;18(12):1367-1376. doi: 10.2174/1389450117666160712092224. PMID: 27411712
Tissue kallikrein, blood pressure regulation, and hypertension: insight from genetic kallikrein deficiency.
Potier L, Waeckel L, Richer C, Roussel R, Bouby N, Alhenc-Gelas F
Biol Chem 2013 Mar;394(3):329-33. doi: 10.1515/hsz-2012-0332. PMID: 23324381
Prediction of preeclampsia.
Myatt L, Miodovnik M
Semin Perinatol 1999 Feb;23(1):45-57. doi: 10.1016/s0146-0005(99)80059-7. PMID: 10102170
Renal kallikrein-kinin system.
Scicli AG, Carretero OA
Kidney Int 1986 Jan;29(1):120-30. doi: 10.1038/ki.1986.14. PMID: 3007849

Recent systematic reviews

The efficacy and adverse events of conventional and second-generation androgen receptor inhibitors for castration-resistant prostate cancer: A network meta-analysis.
Zhang X, Zhang G, Wang J, Bi J
Front Endocrinol (Lausanne) 2023;14:1131033. Epub 2023 Feb 10 doi: 10.3389/fendo.2023.1131033. PMID: 36843606Free PMC Article
Long-term safety outcomes of prekallikrein (Fletcher factor) deficiency: A systematic literature review of case reports.
Girolami A, Rolland C, Sexton D, Vardi M, Bernstein JA
Allergy Asthma Proc 2020 Jan 17;41(1):10-18. doi: 10.2500/aap.2020.41.190005. PMID: 31888778

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