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Hypertonic dehydration

MedGen UID:
205119
Concept ID:
C1112601
Disease or Syndrome
Synonym: Hyperosmolar dehydration
 
HPO: HP:0001986

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHypertonic dehydration

Conditions with this feature

Congenital glucose-galactose malabsorption
MedGen UID:
78647
Concept ID:
C0268186
Disease or Syndrome
Glucose/galactose malabsorption (GGM) is a rare autosomal recessive disorder caused by a defect in glucose and galactose transport across the intestinal brush border. Patients with GGM present with neonatal onset of severe life-threatening watery diarrhea and dehydration. If diagnosed and treated properly, patients can fully recover and show normal growth and development (summary by Xin and Wang, 2011).
Diabetes insipidus, nephrogenic, X-linked
MedGen UID:
288785
Concept ID:
C1563705
Disease or Syndrome
Hereditary nephrogenic diabetes insipidus (NDI) is characterized by inability to concentrate the urine, which results in polyuria (excessive urine production) and polydipsia (excessive thirst). Affected untreated infants usually have poor feeding and failure to thrive, and rapid onset of severe dehydration with illness, hot environment, or the withholding of water. Short stature and secondary dilatation of the ureters and bladder from the high urine volume is common in untreated individuals.
Diabetes insipidus, nephrogenic, autosomal
MedGen UID:
289643
Concept ID:
C1563706
Disease or Syndrome
Hereditary nephrogenic diabetes insipidus (NDI) is characterized by inability to concentrate the urine, which results in polyuria (excessive urine production) and polydipsia (excessive thirst). Affected untreated infants usually have poor feeding and failure to thrive, and rapid onset of severe dehydration with illness, hot environment, or the withholding of water. Short stature and secondary dilatation of the ureters and bladder from the high urine volume is common in untreated individuals.

Professional guidelines

PubMed

Frith J
Age Ageing 2023 Oct 2;52(10) doi: 10.1093/ageing/afad193. PMID: 37847795Free PMC Article
Levine SN, Sanson TH
Drugs 1989 Sep;38(3):462-72. doi: 10.2165/00003495-198938030-00007. PMID: 2680438

Recent clinical studies

Etiology

Lacey J, Corbett J, Forni L, Hooper L, Hughes F, Minto G, Moss C, Price S, Whyte G, Woodcock T, Mythen M, Montgomery H
Ann Med 2019 May-Jun;51(3-4):232-251. Epub 2019 Jun 17 doi: 10.1080/07853890.2019.1628352. PMID: 31204514Free PMC Article
Rinder M, Tran AN, Bennet R, Brytting M, Cassel T, Eriksson M, Frithiof D, Gothefors L, Storsaeter J, Trollfors B, Valdimarsson S, Wennerström M, Johansen K
Scand J Infect Dis 2014 Apr;46(4):294-302. Epub 2014 Feb 3 doi: 10.3109/00365548.2013.876511. PMID: 24484415
Manz F
J Am Coll Nutr 2007 Oct;26(5 Suppl):535S-541S. doi: 10.1080/07315724.2007.10719655. PMID: 17921462
Venkatraman R, Singhi SC
Indian J Pediatr 2006 Jan;73(1):55-60. doi: 10.1007/BF02758261. PMID: 16444062
Manz F, Wentz A
Nutr Rev 2005 Jun;63(6 Pt 2):S2-5. doi: 10.1111/j.1753-4887.2005.tb00150.x. PMID: 16028566

Diagnosis

Lacey J, Corbett J, Forni L, Hooper L, Hughes F, Minto G, Moss C, Price S, Whyte G, Woodcock T, Mythen M, Montgomery H
Ann Med 2019 May-Jun;51(3-4):232-251. Epub 2019 Jun 17 doi: 10.1080/07853890.2019.1628352. PMID: 31204514Free PMC Article
Madea B, Lachenmeier DW
Forensic Sci Int 2005 Dec 1;155(1):1-6. Epub 2004 Dec 18 doi: 10.1016/j.forsciint.2004.10.014. PMID: 16216704
Papadimitriou A, Kipourou K, Manta C, Tapaki G, Philippidis P
J Pediatr Endocrinol Metab 1997 Sep-Oct;10(5):547-50. doi: 10.1515/jpem.1997.10.5.547. PMID: 9401914
Driggers DA
Am Fam Physician 1982 Nov;26(5):189-94. PMID: 7148628
Poole CA, Rowe MI
J Pediatr Surg 1976 Dec;11(6):1011-22. doi: 10.1016/s0022-3468(76)80083-8. PMID: 1003293

Therapy

Kahn A, Blum D, Casimir G, Brachet E
Eur J Pediatr 1981 Feb;135(3):293-6. doi: 10.1007/BF00442106. PMID: 7227384
Birenbaum E, Shahar E, Aladjem M, Brish M
Clin Pediatr (Phila) 1981 Oct;20(10):627-9. doi: 10.1177/000992288102001003. PMID: 6895056
Taitz LS
J Hum Nutr 1977 Oct;31(5):325-8. PMID: 562378
Abrams CA, Phillips LL, Berkowitz C, Blackett PR, Priebe CJ
JAMA 1975 Jun 16;232(11):1136-40. PMID: 1173615
WEIL WB, WALLACE WM
Pediatrics 1956 Feb;17(2):171-83. PMID: 13289208

Prognosis

Sri-On J, Thong-On K, Kredarunsooksree T, Paksopis T, Ruangsiri R
Gerontology 2023;69(8):953-960. Epub 2023 Apr 3 doi: 10.1159/000530359. PMID: 37011597
Lacey J, Corbett J, Forni L, Hooper L, Hughes F, Minto G, Moss C, Price S, Whyte G, Woodcock T, Mythen M, Montgomery H
Ann Med 2019 May-Jun;51(3-4):232-251. Epub 2019 Jun 17 doi: 10.1080/07853890.2019.1628352. PMID: 31204514Free PMC Article
Rinder M, Tran AN, Bennet R, Brytting M, Cassel T, Eriksson M, Frithiof D, Gothefors L, Storsaeter J, Trollfors B, Valdimarsson S, Wennerström M, Johansen K
Scand J Infect Dis 2014 Apr;46(4):294-302. Epub 2014 Feb 3 doi: 10.3109/00365548.2013.876511. PMID: 24484415
Udoshi MB, Trivedi AD, Desai RC, Lichtenstein E
J Natl Med Assoc 1981 Sep;73(9):797-800. PMID: 7277513Free PMC Article
Finberg L
N Engl J Med 1973 Jul 26;289(4):196-8. doi: 10.1056/NEJM197307262890407. PMID: 4576533

Clinical prediction guides

Rinder M, Tran AN, Bennet R, Brytting M, Cassel T, Eriksson M, Frithiof D, Gothefors L, Storsaeter J, Trollfors B, Valdimarsson S, Wennerström M, Johansen K
Scand J Infect Dis 2014 Apr;46(4):294-302. Epub 2014 Feb 3 doi: 10.3109/00365548.2013.876511. PMID: 24484415
Blum D, Brasseur D, Kahn A, Brachet E
J Pediatr Gastroenterol Nutr 1986 Mar-Apr;5(2):232-5. PMID: 3958850
Udoshi MB, Trivedi AD, Desai RC, Lichtenstein E
J Natl Med Assoc 1981 Sep;73(9):797-800. PMID: 7277513Free PMC Article
Kahn A, Blum D, Casimir G, Brachet E
Eur J Pediatr 1981 Feb;135(3):293-6. doi: 10.1007/BF00442106. PMID: 7227384
Birenbaum E, Shahar E, Aladjem M, Brish M
Clin Pediatr (Phila) 1981 Oct;20(10):627-9. doi: 10.1177/000992288102001003. PMID: 6895056

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