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Infectious disease of abdomen

MedGen UID:
205112
Concept ID:
C1112209
Disease or Syndrome
Synonyms: Infection, Intra-Abdominal; Infection, Intraabdominal; Infections, Intra-Abdominal; Infections, Intraabdominal; Intra Abdominal Infections; Intra-Abdominal Infection; Intra-Abdominal Infections; Intraabdominal Infection; Intraabdominal Infections
SNOMED CT: Infectious disease of abdomen (128070006); Infectious disorder of abdomen (128070006); Infection of abdomen (128070006); Abdominal infection (128070006); Abdominal sepsis (128070006)

Definition

Infection in the abdominal cavity resulting from injury, acute intestinal inflammation (e.g., acute appendicitis), intestinal perforation, or complication of abdominal surgery. [from NCI]

Professional guidelines

PubMed

Di Saverio S, Podda M, De Simone B, Ceresoli M, Augustin G, Gori A, Boermeester M, Sartelli M, Coccolini F, Tarasconi A, De' Angelis N, Weber DG, Tolonen M, Birindelli A, Biffl W, Moore EE, Kelly M, Soreide K, Kashuk J, Ten Broek R, Gomes CA, Sugrue M, Davies RJ, Damaskos D, Leppäniemi A, Kirkpatrick A, Peitzman AB, Fraga GP, Maier RV, Coimbra R, Chiarugi M, Sganga G, Pisanu A, De' Angelis GL, Tan E, Van Goor H, Pata F, Di Carlo I, Chiara O, Litvin A, Campanile FC, Sakakushev B, Tomadze G, Demetrashvili Z, Latifi R, Abu-Zidan F, Romeo O, Segovia-Lohse H, Baiocchi G, Costa D, Rizoli S, Balogh ZJ, Bendinelli C, Scalea T, Ivatury R, Velmahos G, Andersson R, Kluger Y, Ansaloni L, Catena F
World J Emerg Surg 2020 Apr 15;15(1):27. doi: 10.1186/s13017-020-00306-3. PMID: 32295644Free PMC Article
Snyder MJ, Guthrie M, Cagle S
Am Fam Physician 2018 Jul 1;98(1):25-33. PMID: 30215950
Bhangu A, Søreide K, Di Saverio S, Assarsson JH, Drake FT
Lancet 2015 Sep 26;386(10000):1278-1287. doi: 10.1016/S0140-6736(15)00275-5. PMID: 26460662

Recent clinical studies

Etiology

Huston JM, Barie PS, Dellinger EP, Forrester JD, Duane TM, Tessier JM, Sawyer RG, Cainzos MA, Rasa K, Chipman JG, Kao LS, Pieracci FM, Colling KP, Heffernan DS, Lester J; Therapeutics and Guidelines Committee
Surg Infect (Larchmt) 2024 Aug;25(6):419-435. Epub 2024 Jul 11 doi: 10.1089/sur.2024.137. PMID: 38990709
Bonomo RA, Chow AW, Edwards MS, Humphries R, Tamma PD, Abrahamian FM, Bessesen M, Dellinger EP, Goldstein E, Hayden MK, Kaye KS, Potoski BA, Rodríguez-Baño J, Sawyer R, Skalweit M, Snydman DR, Pahlke S, Donnelly K, Loveless J
Clin Infect Dis 2024 Oct 4;79(Supplement_3):S81-S87. doi: 10.1093/cid/ciae346. PMID: 38965057
Hecker A, Reichert M, Reuß CJ, Schmoch T, Riedel JG, Schneck E, Padberg W, Weigand MA, Hecker M
Langenbecks Arch Surg 2019 May;404(3):257-271. Epub 2019 Jan 26 doi: 10.1007/s00423-019-01752-7. PMID: 30685836
Mazuski JE, Tessier JM, May AK, Sawyer RG, Nadler EP, Rosengart MR, Chang PK, O'Neill PJ, Mollen KP, Huston JM, Diaz JJ Jr, Prince JM
Surg Infect (Larchmt) 2017 Jan;18(1):1-76. doi: 10.1089/sur.2016.261. PMID: 28085573
Sawyer RG, Claridge JA, Nathens AB, Rotstein OD, Duane TM, Evans HL, Cook CH, O'Neill PJ, Mazuski JE, Askari R, Wilson MA, Napolitano LM, Namias N, Miller PR, Dellinger EP, Watson CM, Coimbra R, Dent DL, Lowry SF, Cocanour CS, West MA, Banton KL, Cheadle WG, Lipsett PA, Guidry CA, Popovsky K; STOP-IT Trial Investigators
N Engl J Med 2015 May 21;372(21):1996-2005. doi: 10.1056/NEJMoa1411162. PMID: 25992746Free PMC Article

Diagnosis

Napolitano LM
Semin Respir Crit Care Med 2022 Feb;43(1):10-27. Epub 2022 Feb 16 doi: 10.1055/s-0041-1741053. PMID: 35172355
Szeto CC, Li PK
Clin J Am Soc Nephrol 2019 Jul 5;14(7):1100-1105. Epub 2019 May 8 doi: 10.2215/CJN.14631218. PMID: 31068338Free PMC Article
Hecker A, Reichert M, Reuß CJ, Schmoch T, Riedel JG, Schneck E, Padberg W, Weigand MA, Hecker M
Langenbecks Arch Surg 2019 May;404(3):257-271. Epub 2019 Jan 26 doi: 10.1007/s00423-019-01752-7. PMID: 30685836
Boldingh QJ, de Vries FE, Boermeester MA
Curr Opin Crit Care 2017 Apr;23(2):159-166. doi: 10.1097/MCC.0000000000000388. PMID: 28107224
Bhangu A, Søreide K, Di Saverio S, Assarsson JH, Drake FT
Lancet 2015 Sep 26;386(10000):1278-1287. doi: 10.1016/S0140-6736(15)00275-5. PMID: 26460662

Therapy

Huston JM, Barie PS, Dellinger EP, Forrester JD, Duane TM, Tessier JM, Sawyer RG, Cainzos MA, Rasa K, Chipman JG, Kao LS, Pieracci FM, Colling KP, Heffernan DS, Lester J; Therapeutics and Guidelines Committee
Surg Infect (Larchmt) 2024 Aug;25(6):419-435. Epub 2024 Jul 11 doi: 10.1089/sur.2024.137. PMID: 38990709
Sartelli M, Coccolini F, Kluger Y, Agastra E, Abu-Zidan FM, Abbas AES, Ansaloni L, Adesunkanmi AK, Atanasov B, Augustin G, Bala M, Baraket O, Baral S, Biffl WL, Boermeester MA, Ceresoli M, Cerutti E, Chiara O, Cicuttin E, Chiarugi M, Coimbra R, Colak E, Corsi D, Cortese F, Cui Y, Damaskos D, De' Angelis N, Delibegovic S, Demetrashvili Z, De Simone B, de Jonge SW, Dhingra S, Di Bella S, Di Marzo F, Di Saverio S, Dogjani A, Duane TM, Enani MA, Fugazzola P, Galante JM, Gachabayov M, Ghnnam W, Gkiokas G, Gomes CA, Griffiths EA, Hardcastle TC, Hecker A, Herzog T, Kabir SMU, Karamarkovic A, Khokha V, Kim PK, Kim JI, Kirkpatrick AW, Kong V, Koshy RM, Kryvoruchko IA, Inaba K, Isik A, Iskandar K, Ivatury R, Labricciosa FM, Lee YY, Leppäniemi A, Litvin A, Luppi D, Machain GM, Maier RV, Marinis A, Marmorale C, Marwah S, Mesina C, Moore EE, Moore FA, Negoi I, Olaoye I, Ordoñez CA, Ouadii M, Peitzman AB, Perrone G, Pikoulis M, Pintar T, Pipitone G, Podda M, Raşa K, Ribeiro J, Rodrigues G, Rubio-Perez I, Sall I, Sato N, Sawyer RG, Segovia Lohse H, Sganga G, Shelat VG, Stephens I, Sugrue M, Tarasconi A, Tochie JN, Tolonen M, Tomadze G, Ulrych J, Vereczkei A, Viaggi B, Gurioli C, Casella C, Pagani L, Baiocchi GL, Catena F
World J Emerg Surg 2021 Sep 25;16(1):49. doi: 10.1186/s13017-021-00387-8. PMID: 34563232Free PMC Article
Sartelli M, Chichom-Mefire A, Labricciosa FM, Hardcastle T, Abu-Zidan FM, Adesunkanmi AK, Ansaloni L, Bala M, Balogh ZJ, Beltrán MA, Ben-Ishay O, Biffl WL, Birindelli A, Cainzos MA, Catalini G, Ceresoli M, Che Jusoh A, Chiara O, Coccolini F, Coimbra R, Cortese F, Demetrashvili Z, Di Saverio S, Diaz JJ, Egiev VN, Ferrada P, Fraga GP, Ghnnam WM, Lee JG, Gomes CA, Hecker A, Herzog T, Kim JI, Inaba K, Isik A, Karamarkovic A, Kashuk J, Khokha V, Kirkpatrick AW, Kluger Y, Koike K, Kong VY, Leppaniemi A, Machain GM, Maier RV, Marwah S, McFarlane ME, Montori G, Moore EE, Negoi I, Olaoye I, Omari AH, Ordonez CA, Pereira BM, Pereira Júnior GA, Pupelis G, Reis T, Sakakhushev B, Sato N, Segovia Lohse HA, Shelat VG, Søreide K, Uhl W, Ulrych J, Van Goor H, Velmahos GC, Yuan KC, Wani I, Weber DG, Zachariah SK, Catena F
World J Emerg Surg 2017;12:29. Epub 2017 Jul 10 doi: 10.1186/s13017-017-0141-6. PMID: 28702076Free PMC Article
Mazuski JE, Tessier JM, May AK, Sawyer RG, Nadler EP, Rosengart MR, Chang PK, O'Neill PJ, Mollen KP, Huston JM, Diaz JJ Jr, Prince JM
Surg Infect (Larchmt) 2017 Jan;18(1):1-76. doi: 10.1089/sur.2016.261. PMID: 28085573
Sawyer RG, Claridge JA, Nathens AB, Rotstein OD, Duane TM, Evans HL, Cook CH, O'Neill PJ, Mazuski JE, Askari R, Wilson MA, Napolitano LM, Namias N, Miller PR, Dellinger EP, Watson CM, Coimbra R, Dent DL, Lowry SF, Cocanour CS, West MA, Banton KL, Cheadle WG, Lipsett PA, Guidry CA, Popovsky K; STOP-IT Trial Investigators
N Engl J Med 2015 May 21;372(21):1996-2005. doi: 10.1056/NEJMoa1411162. PMID: 25992746Free PMC Article

Prognosis

Blot S, Antonelli M, Arvaniti K, Blot K, Creagh-Brown B, de Lange D, De Waele J, Deschepper M, Dikmen Y, Dimopoulos G, Eckmann C, Francois G, Girardis M, Koulenti D, Labeau S, Lipman J, Lipovestky F, Maseda E, Montravers P, Mikstacki A, Paiva JA, Pereyra C, Rello J, Timsit JF, Vogelaers D; Abdominal Sepsis Study (AbSeS) group on behalf of the Trials Group of the European Society of Intensive Care Medicine
Intensive Care Med 2019 Dec;45(12):1703-1717. Epub 2019 Oct 29 doi: 10.1007/s00134-019-05819-3. PMID: 31664501Free PMC Article
Perez KS, Allen SR
JAAPA 2018 Sep;31(9):35-41. doi: 10.1097/01.JAA.0000544304.30954.40. PMID: 30153202
Montravers P, Tubach F, Lescot T, Veber B, Esposito-Farèse M, Seguin P, Paugam C, Lepape A, Meistelman C, Cousson J, Tesniere A, Plantefeve G, Blasco G, Asehnoune K, Jaber S, Lasocki S, Dupont H; DURAPOP Trial Group
Intensive Care Med 2018 Mar;44(3):300-310. Epub 2018 Feb 26 doi: 10.1007/s00134-018-5088-x. PMID: 29484469
Boldingh QJ, de Vries FE, Boermeester MA
Curr Opin Crit Care 2017 Apr;23(2):159-166. doi: 10.1097/MCC.0000000000000388. PMID: 28107224
Sawyer RG, Claridge JA, Nathens AB, Rotstein OD, Duane TM, Evans HL, Cook CH, O'Neill PJ, Mazuski JE, Askari R, Wilson MA, Napolitano LM, Namias N, Miller PR, Dellinger EP, Watson CM, Coimbra R, Dent DL, Lowry SF, Cocanour CS, West MA, Banton KL, Cheadle WG, Lipsett PA, Guidry CA, Popovsky K; STOP-IT Trial Investigators
N Engl J Med 2015 May 21;372(21):1996-2005. doi: 10.1056/NEJMoa1411162. PMID: 25992746Free PMC Article

Clinical prediction guides

Torres A, Wible M, Tawadrous M, Irani P, Stone GG, Quintana A, Debabov D, Burroughs M, Bradford PA, Kollef M
J Antimicrob Chemother 2023 Nov 6;78(11):2672-2682. doi: 10.1093/jac/dkad280. PMID: 37700689Free PMC Article
Kong W, Deng T, Li S, Shu Y, Wu Y
BMC Infect Dis 2023 Apr 21;23(1):256. doi: 10.1186/s12879-023-08209-9. PMID: 37085768Free PMC Article
Awayshih MMA, Nofal MN, Yousef AJ
Pan Afr Med J 2019;34:15. Epub 2019 Sep 6 doi: 10.11604/pamj.2019.34.15.17803. PMID: 31762884Free PMC Article
Montravers P, Tubach F, Lescot T, Veber B, Esposito-Farèse M, Seguin P, Paugam C, Lepape A, Meistelman C, Cousson J, Tesniere A, Plantefeve G, Blasco G, Asehnoune K, Jaber S, Lasocki S, Dupont H; DURAPOP Trial Group
Intensive Care Med 2018 Mar;44(3):300-310. Epub 2018 Feb 26 doi: 10.1007/s00134-018-5088-x. PMID: 29484469
Glass CC, Rangel SJ
Semin Pediatr Surg 2016 Aug;25(4):198-203. Epub 2016 May 10 doi: 10.1053/j.sempedsurg.2016.05.001. PMID: 27521708

Recent systematic reviews

Huston JM, Barie PS, Dellinger EP, Forrester JD, Duane TM, Tessier JM, Sawyer RG, Cainzos MA, Rasa K, Chipman JG, Kao LS, Pieracci FM, Colling KP, Heffernan DS, Lester J; Therapeutics and Guidelines Committee
Surg Infect (Larchmt) 2024 Aug;25(6):419-435. Epub 2024 Jul 11 doi: 10.1089/sur.2024.137. PMID: 38990709
Kumar SS, Collings AT, Lamm R, Haskins IN, Scholz S, Nepal P, Train AT, Athanasiadis DI, Pucher PH, Bradley JF 3rd, Hanna NM, Quinteros F, Narula N, Slater BJ
Surg Endosc 2024 Jun;38(6):2974-2994. Epub 2024 May 13 doi: 10.1007/s00464-024-10813-y. PMID: 38740595
Issaiy M, Zarei D, Saghazadeh A
World J Emerg Surg 2023 Dec 19;18(1):59. doi: 10.1186/s13017-023-00527-2. PMID: 38114983Free PMC Article
de Almeida Leite RM, Seo DJ, Gomez-Eslava B, Hossain S, Lesegretain A, de Souza AV, Bay CP, Zilberstein B, Marchi E, Machado RB, Barchi LC, Ricciardi R
JAMA Surg 2022 Sep 1;157(9):828-834. doi: 10.1001/jamasurg.2022.2937. PMID: 35895073Free PMC Article
Gorter RR, Eker HH, Gorter-Stam MA, Abis GS, Acharya A, Ankersmit M, Antoniou SA, Arolfo S, Babic B, Boni L, Bruntink M, van Dam DA, Defoort B, Deijen CL, DeLacy FB, Go PM, Harmsen AM, van den Helder RS, Iordache F, Ket JC, Muysoms FE, Ozmen MM, Papoulas M, Rhodes M, Straatman J, Tenhagen M, Turrado V, Vereczkei A, Vilallonga R, Deelder JD, Bonjer J
Surg Endosc 2016 Nov;30(11):4668-4690. Epub 2016 Sep 22 doi: 10.1007/s00464-016-5245-7. PMID: 27660247Free PMC Article

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