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Sensitivity, Insulin

MedGen UID:
452799
•Concept ID:
C0920563
•
Pathologic Function
Synonym: Insulin Sensitivity

Professional guidelines

PubMed

Gut microbiota: A new target for T2DM prevention and treatment.
Liu L, Zhang J, Cheng Y, Zhu M, Xiao Z, Ruan G, Wei Y
Front Endocrinol (Lausanne) 2022;13:958218. Epub 2022 Aug 11 doi: 10.3389/fendo.2022.958218. PMID: 36034447Free PMC Article
Potential of Creatine in Glucose Management and Diabetes.
Solis MY, Artioli GG, Gualano B
Nutrients 2021 Feb 9;13(2) doi: 10.3390/nu13020570. PMID: 33572228Free PMC Article
Diet and nutrition in polycystic ovary syndrome (PCOS): pointers for nutritional management.
Farshchi H, Rane A, Love A, Kennedy RL
J Obstet Gynaecol 2007 Nov;27(8):762-73. doi: 10.1080/01443610701667338. PMID: 18097891

Recent clinical studies

Therapy

Evaluation of safety and effectiveness of NAD in different clinical conditions: a systematic review.
Gindri IM, Ferrari G, Pinto LPS, Bicca J, Dos Santos IK, Dallacosta D, Roesler CRM
Am J Physiol Endocrinol Metab 2024 Apr 1;326(4):E417-E427. Epub 2023 Nov 16 doi: 10.1152/ajpendo.00242.2023. PMID: 37971292
Mechanisms of weight loss-induced remission in people with prediabetes: a post-hoc analysis of the randomised, controlled, multicentre Prediabetes Lifestyle Intervention Study (PLIS).
Sandforth A, von Schwartzenberg RJ, Arreola EV, Hanson RL, Sancar G, Katzenstein S, Lange K, Preißl H, Dreher SI, Weigert C, Wagner R, Kantartzis K, Machann J, Schick F, Lehmann R, Peter A, Katsouli N, Ntziachristos V, Dannecker C, Fritsche L, Perakakis N, Heni M, Nawroth PP, Kopf S, Pfeiffer AFH, Kabisch S, Stumvoll M, Schwarz PEH, Hauner H, Lechner A, Seissler J, Yurchenko I, Icks A, Solimena M, Häring HU, Szendroedi J, Schürmann A, de Angelis MH, Blüher M, Roden M, Bornstein SR, Stefan N, Fritsche A, Birkenfeld AL
Lancet Diabetes Endocrinol 2023 Nov;11(11):798-810. Epub 2023 Sep 25 doi: 10.1016/S2213-8587(23)00235-8. PMID: 37769677
Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women.
Yoshino M, Yoshino J, Kayser BD, Patti GJ, Franczyk MP, Mills KF, Sindelar M, Pietka T, Patterson BW, Imai SI, Klein S
Science 2021 Jun 11;372(6547):1224-1229. Epub 2021 Apr 22 doi: 10.1126/science.abe9985. PMID: 33888596Free PMC Article
Inositol as putative integrative treatment for PCOS.
Genazzani AD
Reprod Biomed Online 2016 Dec;33(6):770-780. Epub 2016 Sep 16 doi: 10.1016/j.rbmo.2016.08.024. PMID: 27717596
Very Low-Calorie Diet and 6 Months of Weight Stability in Type 2 Diabetes: Pathophysiological Changes in Responders and Nonresponders.
Steven S, Hollingsworth KG, Al-Mrabeh A, Avery L, Aribisala B, Caslake M, Taylor R
Diabetes Care 2016 May;39(5):808-15. Epub 2016 Mar 21 doi: 10.2337/dc15-1942. PMID: 27002059

Prognosis

Placental IGFBP1 levels during early pregnancy and the risk of insulin resistance and gestational diabetes.
Hivert MF, White F, Allard C, James K, Majid S, Aguet F, Ardlie KG, Florez JC, Edlow AG, Bouchard L, Jacques PÉ, Karumanchi SA, Powe CE
Nat Med 2024 Jun;30(6):1689-1695. Epub 2024 Apr 16 doi: 10.1038/s41591-024-02936-5. PMID: 38627562Free PMC Article
Time-restricted eating did not alter insulin sensitivity or β-cell function in adults with obesity: A randomized pilot study.
Bantle AE, Lau KJ, Wang Q, Malaeb S, Harindhanavudhi T, Manoogian ENC, Panda S, Mashek DG, Chow LS
Obesity (Silver Spring) 2023 Feb;31 Suppl 1(Suppl 1):108-115. Epub 2022 Dec 14 doi: 10.1002/oby.23620. PMID: 36518093Free PMC Article
Association of plasma acylcarnitines with insulin sensitivity, insulin secretion, and prediabetes in a biracial cohort.
Owei I, Umekwe N, Stentz F, Wan J, Dagogo-Jack S
Exp Biol Med (Maywood) 2021 Aug;246(15):1698-1705. Epub 2021 Apr 29 doi: 10.1177/15353702211009493. PMID: 33926260Free PMC Article
Mechanisms of improved glycaemic control after Roux-en-Y gastric bypass.
Bojsen-Møller KN
Dan Med J 2015 Apr;62(4):B5057. PMID: 25872541
Progress in development of an artificial pancreas.
Klonoff DC, Cobelli C, Kovatchev B, Zisser HC
J Diabetes Sci Technol 2009 Sep 1;3(5):1002-4. doi: 10.1177/193229680900300502. PMID: 20144412Free PMC Article

Clinical prediction guides

Placental IGFBP1 levels during early pregnancy and the risk of insulin resistance and gestational diabetes.
Hivert MF, White F, Allard C, James K, Majid S, Aguet F, Ardlie KG, Florez JC, Edlow AG, Bouchard L, Jacques PÉ, Karumanchi SA, Powe CE
Nat Med 2024 Jun;30(6):1689-1695. Epub 2024 Apr 16 doi: 10.1038/s41591-024-02936-5. PMID: 38627562Free PMC Article
Evaluation of safety and effectiveness of NAD in different clinical conditions: a systematic review.
Gindri IM, Ferrari G, Pinto LPS, Bicca J, Dos Santos IK, Dallacosta D, Roesler CRM
Am J Physiol Endocrinol Metab 2024 Apr 1;326(4):E417-E427. Epub 2023 Nov 16 doi: 10.1152/ajpendo.00242.2023. PMID: 37971292
Time-restricted eating did not alter insulin sensitivity or β-cell function in adults with obesity: A randomized pilot study.
Bantle AE, Lau KJ, Wang Q, Malaeb S, Harindhanavudhi T, Manoogian ENC, Panda S, Mashek DG, Chow LS
Obesity (Silver Spring) 2023 Feb;31 Suppl 1(Suppl 1):108-115. Epub 2022 Dec 14 doi: 10.1002/oby.23620. PMID: 36518093Free PMC Article
Association of plasma acylcarnitines with insulin sensitivity, insulin secretion, and prediabetes in a biracial cohort.
Owei I, Umekwe N, Stentz F, Wan J, Dagogo-Jack S
Exp Biol Med (Maywood) 2021 Aug;246(15):1698-1705. Epub 2021 Apr 29 doi: 10.1177/15353702211009493. PMID: 33926260Free PMC Article
Progress in development of an artificial pancreas.
Klonoff DC, Cobelli C, Kovatchev B, Zisser HC
J Diabetes Sci Technol 2009 Sep 1;3(5):1002-4. doi: 10.1177/193229680900300502. PMID: 20144412Free PMC Article

Recent systematic reviews

Evaluation of safety and effectiveness of NAD in different clinical conditions: a systematic review.
Gindri IM, Ferrari G, Pinto LPS, Bicca J, Dos Santos IK, Dallacosta D, Roesler CRM
Am J Physiol Endocrinol Metab 2024 Apr 1;326(4):E417-E427. Epub 2023 Nov 16 doi: 10.1152/ajpendo.00242.2023. PMID: 37971292
Effects of different insulin sensitisers in the management of polycystic ovary syndrome: A systematic review and meta-analysis.
Melin JM, Forslund M, Alesi SJ, Piltonen T, Romualdi D, Spritzer PM, Tay CT, Pena AS, Witchel SF, Mousa A, Teede HJ
Clin Endocrinol (Oxf) 2024 Feb;100(2):149-163. Epub 2023 Nov 7 doi: 10.1111/cen.14983. PMID: 37933831
Fat-free/lean body mass in children with insulin resistance or metabolic syndrome: a systematic review and meta-analysis.
Córdoba-Rodríguez DP, Iglesia I, Gomez-Bruton A, Rodríguez G, Casajús JA, Morales-Devia H, Moreno LA
BMC Pediatr 2022 Jan 22;22(1):58. doi: 10.1186/s12887-021-03041-z. PMID: 35065638Free PMC Article

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