U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Idiopathic thrombocytopenia

MedGen UID:
182524
•Concept ID:
C0920163
•
Disease or Syndrome

Professional guidelines

PubMed

Update on diagnosis and treatment of immune thrombocytopenia.
Sandal R, Mishra K, Jandial A, Sahu KK, Siddiqui AD
Expert Rev Clin Pharmacol 2021 May;14(5):553-568. Epub 2021 Mar 30 doi: 10.1080/17512433.2021.1903315. PMID: 33724124
Thrombocytopenia in pregnancy with different diagnoses: Differential clinical features, treatments, and outcomes.
Wang X, Xu Y, Luo W, Feng H, Luo Y, Wang Y, Liao H
Medicine (Baltimore) 2017 Jul;96(29):e7561. doi: 10.1097/MD.0000000000007561. PMID: 28723784Free PMC Article
Treatment options for chronic immune (idiopathic) thrombocytopenia purpura in children.
Tarantino MD
Semin Hematol 2000 Jan;37(1 Suppl 1):35-41. doi: 10.1016/s0037-1963(00)90117-3. PMID: 10676923

Recent clinical studies

Etiology

Neonatal Outcome of Pregnancies Complicated with Idiopathic Thrombocytopenia.
Zahid S, Asmat R, Ehsan N, Asmat S, Asmat TM
J Coll Physicians Surg Pak 2020 Jul;30(7):745-748. doi: 10.29271/jcpsp.2020.07.745. PMID: 32811607
Consequences of Helicobacter pylori infection in children.
Pacifico L, Anania C, Osborn JF, Ferraro F, Chiesa C
World J Gastroenterol 2010 Nov 7;16(41):5181-94. doi: 10.3748/wjg.v16.i41.5181. PMID: 21049552Free PMC Article
Pediatric laparoscopic splenectomy: benefits of the anterior approach.
de Lagausie P, Bonnard A, Benkerrou M, Rorlich P, de Ribier A, Aigrain Y
Surg Endosc 2004 Jan;18(1):80-2. Epub 2003 Nov 21 doi: 10.1007/s00464-003-9048-2. PMID: 14625739
Management of refractory idiopathic thrombocytopenia.
Firkin BG, Hunt HA, Jane SM
Blood Rev 1988 Sep;2(3):149-56. doi: 10.1016/0268-960x(88)90020-3. PMID: 3052660
Intravenous immunoglobulins as therapeutic agents.
Stiehm ER, Ashida E, Kim KS, Winston DJ, Haas A, Gale RP
Ann Intern Med 1987 Sep;107(3):367-82. doi: 10.7326/0003-4819-107-2-367. PMID: 3304051

Diagnosis

Role of platelets in neonatal necrotizing enterocolitis.
Maheshwari A
Pediatr Res 2021 Apr;89(5):1087-1093. Epub 2020 Jun 29 doi: 10.1038/s41390-020-1038-8. PMID: 32601461Free PMC Article
Clinical applicability of reticulated platelets.
Dusse LM, Freitas LG
Clin Chim Acta 2015 Jan 15;439:143-7. Epub 2014 Oct 23 doi: 10.1016/j.cca.2014.10.024. PMID: 25451948
Evan's syndrome revisited.
Dave P, Krishna K, Diwan AG
J Assoc Physicians India 2012 Apr;60:60-1. PMID: 23029746
Radiology of the spleen.
Robertson F, Leander P, Ekberg O
Eur Radiol 2001;11(1):80-95. doi: 10.1007/s003300000528. PMID: 11194923
Hematologic disorders.
Harrington W
Vox Sang 1986;51 Suppl 2:18-21. doi: 10.1111/j.1423-0410.1986.tb02002.x. PMID: 3765548

Therapy

Clinical applicability of reticulated platelets.
Dusse LM, Freitas LG
Clin Chim Acta 2015 Jan 15;439:143-7. Epub 2014 Oct 23 doi: 10.1016/j.cca.2014.10.024. PMID: 25451948
Autoimmunity: from black water fever to regulatory function.
Chang C
J Autoimmun 2014 Feb-Mar;48-49:1-9. Epub 2014 Feb 1 doi: 10.1016/j.jaut.2013.12.019. PMID: 24491820
Treatment of Helicobacter pylori infection.
Cavallaro LG, Egan B, O'Morain C, Di Mario F
Helicobacter 2006 Oct;11 Suppl 1:36-9. doi: 10.1111/j.1478-405X.2006.00428.x. PMID: 16925610
Intravenous immunoglobulins as therapeutic agents.
Stiehm ER, Ashida E, Kim KS, Winston DJ, Haas A, Gale RP
Ann Intern Med 1987 Sep;107(3):367-82. doi: 10.7326/0003-4819-107-2-367. PMID: 3304051
Hematologic disorders.
Harrington W
Vox Sang 1986;51 Suppl 2:18-21. doi: 10.1111/j.1423-0410.1986.tb02002.x. PMID: 3765548

Prognosis

Thrombocytopenia and Cornelia de Lange syndrome: Still an enigma?
Cavalleri V, Bettini LR, Barboni C, Cereda A, Mariani M, Spinelli M, Gervasini C, Russo S, Biondi A, Jankovic M, Selicorni A
Am J Med Genet A 2016 Jan;170A(1):130-4. Epub 2015 Oct 5 doi: 10.1002/ajmg.a.37390. PMID: 26437745
Clinical applicability of reticulated platelets.
Dusse LM, Freitas LG
Clin Chim Acta 2015 Jan 15;439:143-7. Epub 2014 Oct 23 doi: 10.1016/j.cca.2014.10.024. PMID: 25451948
Evan's syndrome revisited.
Dave P, Krishna K, Diwan AG
J Assoc Physicians India 2012 Apr;60:60-1. PMID: 23029746
Treatment of Helicobacter pylori infection.
Cavallaro LG, Egan B, O'Morain C, Di Mario F
Helicobacter 2006 Oct;11 Suppl 1:36-9. doi: 10.1111/j.1478-405X.2006.00428.x. PMID: 16925610
Radiology of the spleen.
Robertson F, Leander P, Ekberg O
Eur Radiol 2001;11(1):80-95. doi: 10.1007/s003300000528. PMID: 11194923

Clinical prediction guides

A meta-analysis of neonatal outcomes in pregnant women with immune thrombocytopenic purpura.
Luo H, Li D, Gao F, Hong P, Feng W
J Obstet Gynaecol Res 2021 Sep;47(9):2941-2953. Epub 2021 Jun 16 doi: 10.1111/jog.14890. PMID: 34137128
Neonatal Outcome of Pregnancies Complicated with Idiopathic Thrombocytopenia.
Zahid S, Asmat R, Ehsan N, Asmat S, Asmat TM
J Coll Physicians Surg Pak 2020 Jul;30(7):745-748. doi: 10.29271/jcpsp.2020.07.745. PMID: 32811607
Thrombocytopenia in pregnancy with different diagnoses: Differential clinical features, treatments, and outcomes.
Wang X, Xu Y, Luo W, Feng H, Luo Y, Wang Y, Liao H
Medicine (Baltimore) 2017 Jul;96(29):e7561. doi: 10.1097/MD.0000000000007561. PMID: 28723784Free PMC Article
Clinical applicability of reticulated platelets.
Dusse LM, Freitas LG
Clin Chim Acta 2015 Jan 15;439:143-7. Epub 2014 Oct 23 doi: 10.1016/j.cca.2014.10.024. PMID: 25451948
Radiology of the spleen.
Robertson F, Leander P, Ekberg O
Eur Radiol 2001;11(1):80-95. doi: 10.1007/s003300000528. PMID: 11194923

Recent systematic reviews

Lessons Learned From the Clinical Presentation of Common Variable Immunodeficiency Disorders: A Systematic Review and Meta-Analysis.
Janssen LMA, van der Flier M, de Vries E
Front Immunol 2021;12:620709. Epub 2021 Mar 23 doi: 10.3389/fimmu.2021.620709. PMID: 33833753Free PMC Article
Medical treatments for idiopathic thrombocytopenic purpura during pregnancy.
Martí-Carvajal AJ, Peña-Martí GE, Comunián-Carrasco G
Cochrane Database Syst Rev 2009 Oct 7;2009(4):CD007722. doi: 10.1002/14651858.CD007722.pub2. PMID: 19821437Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...