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Unilateral headache

MedGen UID:
163765
•Concept ID:
C0877781
•
Sign or Symptom
Synonyms: Headache, Unilateral; Headaches, Unilateral; Hemicrania; Unilateral Headache; Unilateral Headaches
SNOMED CT: One sided headache (162300006); Unilateral headache (162300006)

Professional guidelines

PubMed

Genetics, pathophysiology, diagnosis, treatment, management, and prevention of migraine.
Khan J, Asoom LIA, Sunni AA, Rafique N, Latif R, Saif SA, Almandil NB, Almohazey D, AbdulAzeez S, Borgio JF
Biomed Pharmacother 2021 Jul;139:111557. Epub 2021 May 17 doi: 10.1016/j.biopha.2021.111557. PMID: 34243621
Retinal Migraine: Evaluation and Management.
Maher ME, Kingston W
Curr Neurol Neurosci Rep 2021 May 11;21(7):35. doi: 10.1007/s11910-021-01122-1. PMID: 33973068
Hemicrania Continua: a Clinical Perspective on Diagnosis and Management.
Mehta A, Chilakamarri P, Zubair A, Kuruvilla DE
Curr Neurol Neurosci Rep 2018 Oct 17;18(12):95. doi: 10.1007/s11910-018-0899-2. PMID: 30328517

Recent clinical studies

Etiology

Trigeminal Autonomic Cephalalgias.
Burish MJ, Rozen TD
Neurol Clin 2019 Nov;37(4):847-869. Epub 2019 Aug 24 doi: 10.1016/j.ncl.2019.07.001. PMID: 31563236
Cluster Headache and Other Trigeminal Autonomic Cephalalgias.
McGeeney BE
Semin Neurol 2018 Dec;38(6):603-607. Epub 2018 Dec 6 doi: 10.1055/s-0038-1673682. PMID: 30522134
Therapeutic Approaches for the Management of Trigeminal Autonomic Cephalalgias.
Wei DY, Jensen RH
Neurotherapeutics 2018 Apr;15(2):346-360. doi: 10.1007/s13311-018-0618-3. PMID: 29516437Free PMC Article
Neurobiology and sleep disorders in cluster headache.
Barloese MC
J Headache Pain 2015;16:562. Epub 2015 Aug 20 doi: 10.1186/s10194-015-0562-0. PMID: 26289164Free PMC Article
Headache in stroke.
Vestergaard K, Andersen G, Nielsen MI, Jensen TS
Stroke 1993 Nov;24(11):1621-4. doi: 10.1161/01.str.24.11.1621. PMID: 8236332

Diagnosis

Recent advances in diagnosing, managing, and understanding the pathophysiology of cluster headache.
Petersen AS, Lund N, Goadsby PJ, Belin AC, Wang SJ, Fronczek R, Burish M, Cho SJ, Peres MFP, Jensen RH
Lancet Neurol 2024 Jul;23(7):712-724. doi: 10.1016/S1474-4422(24)00143-1. PMID: 38876749
Hemicrania Continua: An Update.
Al-Khazali HM, Christensen RH, Lambru G, Dodick DW, Ashina H
Curr Pain Headache Rep 2023 Oct;27(10):543-550. Epub 2023 Aug 11 doi: 10.1007/s11916-023-01156-9. PMID: 37566220
Genetics, pathophysiology, diagnosis, treatment, management, and prevention of migraine.
Khan J, Asoom LIA, Sunni AA, Rafique N, Latif R, Saif SA, Almandil NB, Almohazey D, AbdulAzeez S, Borgio JF
Biomed Pharmacother 2021 Jul;139:111557. Epub 2021 May 17 doi: 10.1016/j.biopha.2021.111557. PMID: 34243621
Trigeminal Autonomic Cephalalgias.
Burish MJ, Rozen TD
Neurol Clin 2019 Nov;37(4):847-869. Epub 2019 Aug 24 doi: 10.1016/j.ncl.2019.07.001. PMID: 31563236
Diagnosing cervicogenic headache.
Antonaci F, Bono G, Chimento P
J Headache Pain 2006 Jun;7(3):145-8. Epub 2006 Mar 31 doi: 10.1007/s10194-006-0277-3. PMID: 16575502Free PMC Article

Therapy

Recent advances in diagnosing, managing, and understanding the pathophysiology of cluster headache.
Petersen AS, Lund N, Goadsby PJ, Belin AC, Wang SJ, Fronczek R, Burish M, Cho SJ, Peres MFP, Jensen RH
Lancet Neurol 2024 Jul;23(7):712-724. doi: 10.1016/S1474-4422(24)00143-1. PMID: 38876749
Hemicrania Continua: An Update.
Al-Khazali HM, Christensen RH, Lambru G, Dodick DW, Ashina H
Curr Pain Headache Rep 2023 Oct;27(10):543-550. Epub 2023 Aug 11 doi: 10.1007/s11916-023-01156-9. PMID: 37566220
Pharmacotherapy for Cluster Headache.
Brandt RB, Doesborg PGG, Haan J, Ferrari MD, Fronczek R
CNS Drugs 2020 Feb;34(2):171-184. doi: 10.1007/s40263-019-00696-2. PMID: 31997136Free PMC Article
Trigeminal Autonomic Cephalalgias.
Burish MJ, Rozen TD
Neurol Clin 2019 Nov;37(4):847-869. Epub 2019 Aug 24 doi: 10.1016/j.ncl.2019.07.001. PMID: 31563236
Cluster headache: present and future therapy.
Leone M, Giustiniani A, Cecchini AP
Neurol Sci 2017 May;38(Suppl 1):45-50. doi: 10.1007/s10072-017-2924-7. PMID: 28527055

Prognosis

The pathophysiology of the trigeminal autonomic cephalalgias, with clinical implications.
Barloese MCJ
Clin Auton Res 2018 Jun;28(3):315-324. Epub 2017 Sep 23 doi: 10.1007/s10286-017-0468-9. PMID: 28942483
Neurobiology and sleep disorders in cluster headache.
Barloese MC
J Headache Pain 2015;16:562. Epub 2015 Aug 20 doi: 10.1186/s10194-015-0562-0. PMID: 26289164Free PMC Article
Epidemiology of fixed unilateral headaches.
Leone M, Cecchini AP, Mea E, Tullo V, Bussone G
Cephalalgia 2008 Jul;28 Suppl 1:8-11. doi: 10.1111/j.1468-2982.2008.01607.x. PMID: 18494985
Cervicocranial arterial dissection.
Anson J, Crowell RM
Neurosurgery 1991 Jul;29(1):89-96. doi: 10.1097/00006123-199107000-00015. PMID: 1870693
Raeder's syndrome. A clinical review.
Grimson BS, Thompson HS
Surv Ophthalmol 1980 Jan-Feb;24(4):199-210. doi: 10.1016/0039-6257(80)90041-7. PMID: 6244681

Clinical prediction guides

Visual Processing During the Interictal Period Between Migraines: A Meta-Analysis.
Sezai T, Murphy MJ, Riddell N, Nguyen V, Crewther SG
Neuropsychol Rev 2023 Dec;33(4):765-782. Epub 2022 Sep 17 doi: 10.1007/s11065-022-09562-3. PMID: 36115887Free PMC Article
The locus of Action of CGRPergic Monoclonal Antibodies Against Migraine: Peripheral Over Central Mechanisms.
González-Hernández A, Marichal-Cancino BA, García-Boll E, Villalón CM
CNS Neurol Disord Drug Targets 2020;19(5):344-359. doi: 10.2174/1871527319666200618144637. PMID: 32552657
Subbasal Nerve Plexus Changes in Chronic Migraine.
Shetty R, Deshmukh R, Shroff R, Dedhiya C, Jayadev C
Cornea 2018 Jan;37(1):72-75. doi: 10.1097/ICO.0000000000001403. PMID: 28990996
Deep brain stimulation in headache.
Leone M, Proietti Cecchini A
Cephalalgia 2016 Oct;36(12):1143-1148. Epub 2016 Jul 20 doi: 10.1177/0333102415607176. PMID: 26646787
Prevalence and clinical characteristics of headache in adolescents: a Croatian epidemiological study.
Cvetković VV, Plavec D, Lovrenčić-Huzjan A, Strineka M, Ažman D, Bene R
Cephalalgia 2014 Apr;34(4):289-97. Epub 2013 Oct 14 doi: 10.1177/0333102413507636. PMID: 24126946

Recent systematic reviews

The critical role of neuroimaging in hemicrania continua: A systematic review and case series.
Yildiz Goksel H, Bilgin S, Digre K, Cortez MM, Ozudogru SN
Headache 2024 Jun;64(6):674-684. Epub 2024 May 23 doi: 10.1111/head.14728. PMID: 38780233
Comprehensive analysis of genes associated with migraine in the Indian population: a meta-analysis of genetic association studies with trial sequential analysis.
Sudershan A, Pushap AC, Bhagat M, Sharma I, Kumar H, Digra SK, Kumar P
Sci Rep 2023 Nov 4;13(1):19070. doi: 10.1038/s41598-023-45531-3. PMID: 37925562Free PMC Article
A Systematic Review of the Diagnostic Criteria Used to Select Participants in Randomised Controlled Trials of Interventions Used to Treat Cervicogenic Headache.
Avijgan M, Thomas LC, Osmotherly PG, Bolton PS
Headache 2020 Jan;60(1):15-27. Epub 2019 Dec 9 doi: 10.1111/head.13719. PMID: 31820439
Occipital Condyle Syndrome: A Red Flag for Malignancy. Comprehensive Literature Review and New Case Report.
Rodríguez-Pardo J, Lara-Lara M, Sanz-Cuesta BE, Fuentes B, Díez-Tejedor E
Headache 2017 May;57(5):699-708. Epub 2016 Dec 21 doi: 10.1111/head.13008. PMID: 28000214

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