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Mercurial Neuroanesthenia

MedGen UID:
155943
•Concept ID:
C0751857
•
Disease or Syndrome
Synonym: Neuroanesthenia, Mercurial

Professional guidelines

PubMed

Epidemiology, clinical presentation, treatment, and follow-up of chronic mercury poisoning in China: a retrospective analysis.
Yawei S, Jianhai L, Junxiu Z, Xiaobo P, Zewu Q
BMC Pharmacol Toxicol 2021 May 3;22(1):25. doi: 10.1186/s40360-021-00493-y. PMID: 33941274Free PMC Article
Human health risk assessment of mercury vapor around artisanal small-scale gold mining area, Palu city, Central Sulawesi, Indonesia.
Nakazawa K, Nagafuchi O, Kawakami T, Inoue T, Yokota K, Serikawa Y, Cyio B, Elvince R
Ecotoxicol Environ Saf 2016 Feb;124:155-162. Epub 2015 Oct 26 doi: 10.1016/j.ecoenv.2015.09.042. PMID: 26513531
Neurodevelopmental toxicity of methylmercury: Laboratory animal data and their contribution to human risk assessment.
Castoldi AF, Onishchenko N, Johansson C, Coccini T, Roda E, Vahter M, Ceccatelli S, Manzo L
Regul Toxicol Pharmacol 2008 Jul;51(2):215-29. Epub 2008 Mar 25 doi: 10.1016/j.yrtph.2008.03.005. PMID: 18482784

Recent clinical studies

Etiology

Neurotoxic effects of heavy metal pollutants in the environment: Focusing on epigenetic mechanisms.
Yu G, Wu L, Su Q, Ji X, Zhou J, Wu S, Tang Y, Li H
Environ Pollut 2024 Mar 15;345:123563. Epub 2024 Feb 13 doi: 10.1016/j.envpol.2024.123563. PMID: 38355086
Functional consequences of lead and mercury exposomes in the heart.
Ferreira G, Santander A, Chavarría L, Cardozo R, Savio F, Sobrevia L, Nicolson GL
Mol Aspects Med 2022 Oct;87:101048. Epub 2021 Nov 14 doi: 10.1016/j.mam.2021.101048. PMID: 34785060
Special issue on fish, mercury and health.
Cranmer JS
Neurotoxicology 2020 Jul;79:209-210. Epub 2020 May 7 doi: 10.1016/j.neuro.2020.04.001. PMID: 32387194
Toxicity of mercury: Molecular evidence.
Yang L, Zhang Y, Wang F, Luo Z, Guo S, Strähle U
Chemosphere 2020 Apr;245:125586. Epub 2019 Dec 16 doi: 10.1016/j.chemosphere.2019.125586. PMID: 31881386
Neurotoxicity of metals.
Caito S, Aschner M
Handb Clin Neurol 2015;131:169-89. doi: 10.1016/B978-0-444-62627-1.00011-1. PMID: 26563789

Diagnosis

Special issue on fish, mercury and health.
Cranmer JS
Neurotoxicology 2020 Jul;79:209-210. Epub 2020 May 7 doi: 10.1016/j.neuro.2020.04.001. PMID: 32387194
Gender differences in the neurotoxicity of metals in children.
Llop S, Lopez-Espinosa MJ, Rebagliato M, Ballester F
Toxicology 2013 Sep 6;311(1-2):3-12. Epub 2013 Apr 28 doi: 10.1016/j.tox.2013.04.015. PMID: 23632092
Kawasaki's disease, acrodynia, and mercury.
Mutter J, Yeter D
Curr Med Chem 2008;15(28):3000-10. doi: 10.2174/092986708786848712. PMID: 19075648
Neurophysiological evidence of methylmercury neurotoxicity.
Murata K, Grandjean P, Dakeishi M
Am J Ind Med 2007 Oct;50(10):765-71. doi: 10.1002/ajim.20471. PMID: 17450510
Overview of the clinical toxicity of mercury.
Magos L, Clarkson TW
Ann Clin Biochem 2006 Jul;43(Pt 4):257-68. doi: 10.1258/000456306777695654. PMID: 16824275

Therapy

Special issue on fish, mercury and health.
Cranmer JS
Neurotoxicology 2020 Jul;79:209-210. Epub 2020 May 7 doi: 10.1016/j.neuro.2020.04.001. PMID: 32387194
Chronic Neurological Disease Due to Methylmercury Poisoning.
Jackson AC
Can J Neurol Sci 2018 Nov;45(6):620-623. Epub 2018 Oct 3 doi: 10.1017/cjn.2018.323. PMID: 30278852
Neurotoxicity of Metal Mixtures.
Andrade VM, Aschner M, Marreilha Dos Santos AP
Adv Neurobiol 2017;18:227-265. doi: 10.1007/978-3-319-60189-2_12. PMID: 28889271
Gender differences in the neurotoxicity of metals in children.
Llop S, Lopez-Espinosa MJ, Rebagliato M, Ballester F
Toxicology 2013 Sep 6;311(1-2):3-12. Epub 2013 Apr 28 doi: 10.1016/j.tox.2013.04.015. PMID: 23632092
Toxicology of alkylmercury compounds.
Aschner M, Onishchenko N, Ceccatelli S
Met Ions Life Sci 2010;7:403-34. Epub 2010 Jan 30 doi: 10.1039/BK9781847551771-00403. PMID: 20877814

Prognosis

Mercury Involvement in Neuronal Damage and in Neurodegenerative Diseases.
Cariccio VL, Samà A, Bramanti P, Mazzon E
Biol Trace Elem Res 2019 Feb;187(2):341-356. Epub 2018 May 18 doi: 10.1007/s12011-018-1380-4. PMID: 29777524
Metal chelators and neurotoxicity: lead, mercury, and arsenic.
Bjørklund G, Mutter J, Aaseth J
Arch Toxicol 2017 Dec;91(12):3787-3797. Epub 2017 Oct 24 doi: 10.1007/s00204-017-2100-0. PMID: 29063135
Mercury exposure: effects across the lifespan.
Taber KH, Hurley RA
J Neuropsychiatry Clin Neurosci 2008 Fall;20(4):iv-389. doi: 10.1176/jnp.2008.20.4.iv. PMID: 19196923
Thimerosal and autism? A plausible hypothesis that should not be dismissed.
Blaxill MF, Redwood L, Bernard S
Med Hypotheses 2004;62(5):788-94. doi: 10.1016/j.mehy.2003.11.033. PMID: 15082108
Glutamate uptake.
Danbolt NC
Prog Neurobiol 2001 Sep;65(1):1-105. doi: 10.1016/s0301-0082(00)00067-8. PMID: 11369436

Clinical prediction guides

Mercury Involvement in Neuronal Damage and in Neurodegenerative Diseases.
Cariccio VL, Samà A, Bramanti P, Mazzon E
Biol Trace Elem Res 2019 Feb;187(2):341-356. Epub 2018 May 18 doi: 10.1007/s12011-018-1380-4. PMID: 29777524
Mercury Exposure and Heart Rate Variability: a Systematic Review.
Gribble MO, Cheng A, Berger RD, Rosman L, Guallar E
Curr Environ Health Rep 2015 Sep;2(3):304-14. doi: 10.1007/s40572-015-0053-0. PMID: 26231507Free PMC Article
Environmental toxicity and poor cognitive outcomes in children and adults.
Liu J, Lewis G
J Environ Health 2014 Jan-Feb;76(6):130-8. PMID: 24645424Free PMC Article
Neurophysiological evidence of methylmercury neurotoxicity.
Murata K, Grandjean P, Dakeishi M
Am J Ind Med 2007 Oct;50(10):765-71. doi: 10.1002/ajim.20471. PMID: 17450510
Overview of the clinical toxicity of mercury.
Magos L, Clarkson TW
Ann Clin Biochem 2006 Jul;43(Pt 4):257-68. doi: 10.1258/000456306777695654. PMID: 16824275

Recent systematic reviews

Human exposure to mercury and its hematological effects: a systematic review.
Vianna ADS, Matos EP, Jesus IM, Asmus CIRF, Câmara VM
Cad Saude Publica 2019 Feb 11;35(2):e00091618. doi: 10.1590/0102-311X00091618. PMID: 30758455
Mercury Exposure and Heart Rate Variability: a Systematic Review.
Gribble MO, Cheng A, Berger RD, Rosman L, Guallar E
Curr Environ Health Rep 2015 Sep;2(3):304-14. doi: 10.1007/s40572-015-0053-0. PMID: 26231507Free PMC Article
Defining a lowest observable adverse effect hair concentrations of mercury for neurodevelopmental effects of prenatal methylmercury exposure through maternal fish consumption: a systematic review.
Schoeman K, Bend JR, Hill J, Nash K, Koren G
Ther Drug Monit 2009 Dec;31(6):670-82. doi: 10.1097/FTD.0b013e3181bb0ea1. PMID: 19865003

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