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Coma, Post-Traumatic, Prolonged

MedGen UID:
155930
•Concept ID:
C0751812
•
Disease or Syndrome
Synonyms: Coma, Post Concussive; Coma, Post-Concussive; Comas, Post-Concussive; Post-Concussive Coma; Post-Concussive Comas

Professional guidelines

PubMed

Which elements of hospital-based clinical decision support tools for the assessment and management of children with head injury can be adapted for use by paramedics in prehospital care? A systematic mapping review and narrative synthesis.
Proctor A, Lyttle M, Billing J, Shaw P, Simpson J, Voss S, Benger JR
BMJ Open 2024 Feb 13;14(2):e078363. doi: 10.1136/bmjopen-2023-078363. PMID: 38355171Free PMC Article
Multiple intracranial lesions in head injury: clinical considerations, prognostic factors, management, and results in 95 patients.
Caroli M, Locatelli M, Campanella R, Balbi S, Martinelli F, Arienta C
Surg Neurol 2001 Aug;56(2):82-8. doi: 10.1016/s0090-3019(01)00540-7. PMID: 11580939

Recent clinical studies

Etiology

Post Traumatic Hydrocephalus in Indian Subpopulation: An Institutional Experience.
Jha VC, Jha N
Turk Neurosurg 2023;33(1):10-17. doi: 10.5137/1019-5149.JTN.30032-20.2. PMID: 33759153
Risk Factors Associated with the Outcome of Post-Traumatic Hydrocephalus.
Sun S, Zhou H, Ding ZZ, Shi H
Scand J Surg 2019 Sep;108(3):265-270. Epub 2018 Nov 14 doi: 10.1177/1457496918812210. PMID: 30428813
Emotional reserve and prolonged post-concussive symptoms and disability: a Swedish prospective 1-year mild traumatic brain injury cohort study.
Oldenburg C, Lundin A, Edman G, Deboussard CN, Bartfai A
BMJ Open 2018 Jul 6;8(7):e020884. doi: 10.1136/bmjopen-2017-020884. PMID: 29982209Free PMC Article
Placebo-controlled trial of amantadine for severe traumatic brain injury.
Giacino JT, Whyte J, Bagiella E, Kalmar K, Childs N, Khademi A, Eifert B, Long D, Katz DI, Cho S, Yablon SA, Luther M, Hammond FM, Nordenbo A, Novak P, Mercer W, Maurer-Karattup P, Sherer M
N Engl J Med 2012 Mar 1;366(9):819-26. doi: 10.1056/NEJMoa1102609. PMID: 22375973
Epidemiological findings in traumatic post-comatose unawareness.
Sazbon L, Costeff H, Groswasser Z
Brain Inj 1992 Jul-Aug;6(4):359-62. doi: 10.3109/02699059209034950. PMID: 1638269

Diagnosis

Predisposing Factors and Outcome of Acute Kidney Injury After Blunt Trauma: A 10-Year Study.
Al-Thani H, Ramzee AF, Asim M, El-Menyar A
J Surg Res 2023 Apr;284:193-203. Epub 2022 Dec 29 doi: 10.1016/j.jss.2022.12.001. PMID: 36586312
Productive mental disorders in post-traumatic disturbances of consciousness.
Zaitsev OS
Zh Vopr Neirokhir Im N N Burdenko 2014;78(1):46-8; discussion 49. PMID: 24761596
Year in review 2008: Critical Care--trauma.
Metzger JC, Eastman AL, Pepe PE
Crit Care 2009;13(5):226. Epub 2009 Oct 21 doi: 10.1186/cc7960. PMID: 19863766Free PMC Article
Transient post-traumatic locked-in syndrome: a case report and a literature review.
Carrai R, Grippo A, Fossi S, Campolo MC, Lanzo G, Pinto F, Amantini A
Neurophysiol Clin 2009 Apr;39(2):95-100. Epub 2008 Dec 25 doi: 10.1016/j.neucli.2008.11.003. PMID: 19467439
Incidence and prognostic value of spindles in post-traumatic coma.
Rumpl E, Prugger M, Bauer G, Gerstenbrand F, Hackl JM, Pallua A
Electroencephalogr Clin Neurophysiol 1983 Nov;56(5):420-9. doi: 10.1016/0013-4694(83)90224-9. PMID: 6194958

Therapy

Elevated risk of venous thromboembolism among post-traumatic brain injury patients requiring pharmaceutical immobilization.
Zhang M, Parikh B, Dirlikov B, Cage T, Lee M, Singh H
J Clin Neurosci 2020 May;75:66-70. Epub 2020 Mar 31 doi: 10.1016/j.jocn.2020.03.028. PMID: 32245600Free PMC Article
Impact of anti-epileptic drug choice on discharge in acute traumatic brain injury patients.
Harris L, Hateley S, Tsang KT, Wilson M, Seemungal BM
J Neurol 2020 Jun;267(6):1774-1779. Epub 2020 Mar 4 doi: 10.1007/s00415-020-09769-5. PMID: 32130500Free PMC Article
Systematic review and meta-analysis found significant risk of brain injury and neurosurgery in alert children after a post-traumatic seizure.
Zanetto L, Da Dalt L, Daverio M, Dunning J, Frigo AC, Nigrovic LE, Bressan S
Acta Paediatr 2019 Oct;108(10):1841-1849. Epub 2019 Apr 29 doi: 10.1111/apa.14810. PMID: 30951221
Placebo-controlled trial of amantadine for severe traumatic brain injury.
Giacino JT, Whyte J, Bagiella E, Kalmar K, Childs N, Khademi A, Eifert B, Long D, Katz DI, Cho S, Yablon SA, Luther M, Hammond FM, Nordenbo A, Novak P, Mercer W, Maurer-Karattup P, Sherer M
N Engl J Med 2012 Mar 1;366(9):819-26. doi: 10.1056/NEJMoa1102609. PMID: 22375973
Posttraumatic amnesia and recall of a traumatic event following traumatic brain injury.
Feinstein A, Hershkop S, Ouchterlony D, Jardine A, McCullagh S
J Neuropsychiatry Clin Neurosci 2002 Winter;14(1):25-30. doi: 10.1176/jnp.14.1.25. PMID: 11884651

Prognosis

Risk Factors Associated with the Outcome of Post-Traumatic Hydrocephalus.
Sun S, Zhou H, Ding ZZ, Shi H
Scand J Surg 2019 Sep;108(3):265-270. Epub 2018 Nov 14 doi: 10.1177/1457496918812210. PMID: 30428813
Productive mental disorders in post-traumatic disturbances of consciousness.
Zaitsev OS
Zh Vopr Neirokhir Im N N Burdenko 2014;78(1):46-8; discussion 49. PMID: 24761596
Transient post-traumatic locked-in syndrome: a case report and a literature review.
Carrai R, Grippo A, Fossi S, Campolo MC, Lanzo G, Pinto F, Amantini A
Neurophysiol Clin 2009 Apr;39(2):95-100. Epub 2008 Dec 25 doi: 10.1016/j.neucli.2008.11.003. PMID: 19467439
Epidemiological findings in traumatic post-comatose unawareness.
Sazbon L, Costeff H, Groswasser Z
Brain Inj 1992 Jul-Aug;6(4):359-62. doi: 10.3109/02699059209034950. PMID: 1638269
Incidence, CT findings and rehabilitation outcome of patients with communicative hydrocephalus following severe head injury.
Groswasser Z, Cohen M, Reider-Groswasser I, Stern MJ
Brain Inj 1988 Oct-Dec;2(4):267-72. doi: 10.3109/02699058809150897. PMID: 3203174

Clinical prediction guides

Post Traumatic Hydrocephalus in Indian Subpopulation: An Institutional Experience.
Jha VC, Jha N
Turk Neurosurg 2023;33(1):10-17. doi: 10.5137/1019-5149.JTN.30032-20.2. PMID: 33759153
Risk Factors Associated with the Outcome of Post-Traumatic Hydrocephalus.
Sun S, Zhou H, Ding ZZ, Shi H
Scand J Surg 2019 Sep;108(3):265-270. Epub 2018 Nov 14 doi: 10.1177/1457496918812210. PMID: 30428813
Emotional reserve and prolonged post-concussive symptoms and disability: a Swedish prospective 1-year mild traumatic brain injury cohort study.
Oldenburg C, Lundin A, Edman G, Deboussard CN, Bartfai A
BMJ Open 2018 Jul 6;8(7):e020884. doi: 10.1136/bmjopen-2017-020884. PMID: 29982209Free PMC Article
Placebo-controlled trial of amantadine for severe traumatic brain injury.
Giacino JT, Whyte J, Bagiella E, Kalmar K, Childs N, Khademi A, Eifert B, Long D, Katz DI, Cho S, Yablon SA, Luther M, Hammond FM, Nordenbo A, Novak P, Mercer W, Maurer-Karattup P, Sherer M
N Engl J Med 2012 Mar 1;366(9):819-26. doi: 10.1056/NEJMoa1102609. PMID: 22375973
Year in review 2008: Critical Care--trauma.
Metzger JC, Eastman AL, Pepe PE
Crit Care 2009;13(5):226. Epub 2009 Oct 21 doi: 10.1186/cc7960. PMID: 19863766Free PMC Article

Recent systematic reviews

Which elements of hospital-based clinical decision support tools for the assessment and management of children with head injury can be adapted for use by paramedics in prehospital care? A systematic mapping review and narrative synthesis.
Proctor A, Lyttle M, Billing J, Shaw P, Simpson J, Voss S, Benger JR
BMJ Open 2024 Feb 13;14(2):e078363. doi: 10.1136/bmjopen-2023-078363. PMID: 38355171Free PMC Article
Systematic review and meta-analysis found significant risk of brain injury and neurosurgery in alert children after a post-traumatic seizure.
Zanetto L, Da Dalt L, Daverio M, Dunning J, Frigo AC, Nigrovic LE, Bressan S
Acta Paediatr 2019 Oct;108(10):1841-1849. Epub 2019 Apr 29 doi: 10.1111/apa.14810. PMID: 30951221

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