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Basal Cell Cancers

MedGen UID:
155906
•Concept ID:
C0751676
•
Neoplastic Process
Synonyms: Basal Cell Cancer; Cancer, Basal Cell; Cancers, Basal Cell; Cell Cancer, Basal; Cell Cancers, Basal

Professional guidelines

PubMed

Recognising Skin Cancer in Primary Care.
Jones OT, Ranmuthu CKI, Hall PN, Funston G, Walter FM
Adv Ther 2020 Jan;37(1):603-616. Epub 2019 Nov 16 doi: 10.1007/s12325-019-01130-1. PMID: 31734824Free PMC Article
Evaluation and initial management of the patient with facial skin cancer.
Ho T, Byrne PJ
Facial Plast Surg Clin North Am 2009 Aug;17(3):301-7. doi: 10.1016/j.fsc.2009.04.002. PMID: 19698912
Risk assessment and early detection of skin cancers.
Maguire-Eisen M
Semin Oncol Nurs 2003 Feb;19(1):43-51. doi: 10.1053/sonu.2003.50003. PMID: 12638380

Recent clinical studies

Etiology

Superficial Basal Cell Cancers Demonstrate Higher Rates of Mixed Histology on High-Risk Anatomical Sites.
Petersen ET, Ahmed SR, Pradhan D, MacFarlane DF
Dermatol Surg 2020 Jun;46(6):747-751. doi: 10.1097/DSS.0000000000002162. PMID: 31652222
Psychosocial and Cultural Determinants of Interest and Uptake of Skin Cancer Genetic Testing in Diverse Primary Care.
Hay JL, Meyer White K, Sussman A, Kaphingst K, Guest D, Schofield E, Dailey YT, Robers E, Schwartz MR, Zielaskowski K, Li Y, Buller D, Hunley K, Berwick M
Public Health Genomics 2019;22(1-2):58-68. Epub 2019 Aug 22 doi: 10.1159/000501985. PMID: 31437847Free PMC Article
Cutaneous malignancies in HIV.
Chang AY, Doiron P, Maurer T
Curr Opin HIV AIDS 2017 Jan;12(1):57-62. doi: 10.1097/COH.0000000000000338. PMID: 27875372
The effect of sunscreen on melanoma risk.
Mulliken JS, Russak JE, Rigel DS
Dermatol Clin 2012 Jul;30(3):369-76. Epub 2012 Jun 15 doi: 10.1016/j.det.2012.04.002. PMID: 22800545
Radiation-sensitive genetically susceptible pediatric sub-populations.
Kleinerman RA
Pediatr Radiol 2009 Feb;39 Suppl 1(Suppl 1):S27-31. Epub 2008 Dec 16 doi: 10.1007/s00247-008-1015-6. PMID: 19083227Free PMC Article

Diagnosis

Non-Squamous, Non-Basal Cell Cancers of the Skin: Exploring Associations Between Site of Disease and Depression.
Almodallal Y, Lee MK, Le-Rademacher JG, Smith CJ, Carroll JL, Robinson SI, Jatoi A
Am J Hosp Palliat Care 2021 Aug;38(8):979-982. Epub 2020 Nov 15 doi: 10.1177/1049909120969605. PMID: 33191782
Superficial Basal Cell Cancers Demonstrate Higher Rates of Mixed Histology on High-Risk Anatomical Sites.
Petersen ET, Ahmed SR, Pradhan D, MacFarlane DF
Dermatol Surg 2020 Jun;46(6):747-751. doi: 10.1097/DSS.0000000000002162. PMID: 31652222
Radiation-sensitive genetically susceptible pediatric sub-populations.
Kleinerman RA
Pediatr Radiol 2009 Feb;39 Suppl 1(Suppl 1):S27-31. Epub 2008 Dec 16 doi: 10.1007/s00247-008-1015-6. PMID: 19083227Free PMC Article
Grenz ray-induced nonmelanoma skin cancer.
Frentz G
J Am Acad Dermatol 1989 Sep;21(3 Pt 1):475-8. doi: 10.1016/s0190-9622(89)70210-3. PMID: 2674211
Nevoid basal-cell carcinoma syndrome.
Gorlin RJ
Medicine (Baltimore) 1987 Mar;66(2):98-113. doi: 10.1097/00005792-198703000-00002. PMID: 3547011

Therapy

Sustained Suppression of Gorlin Syndrome-Associated Basal Cell Carcinomas with Vismodegib or Sonidegib: A Case Series.
Wescott R, Samlowski W
Curr Oncol 2023 Oct 16;30(10):9156-9167. doi: 10.3390/curroncol30100661. PMID: 37887561Free PMC Article
The effect of sunscreen on melanoma risk.
Mulliken JS, Russak JE, Rigel DS
Dermatol Clin 2012 Jul;30(3):369-76. Epub 2012 Jun 15 doi: 10.1016/j.det.2012.04.002. PMID: 22800545
Grenz ray-induced nonmelanoma skin cancer.
Frentz G
J Am Acad Dermatol 1989 Sep;21(3 Pt 1):475-8. doi: 10.1016/s0190-9622(89)70210-3. PMID: 2674211
Historical perspectives of tretinoin.
Stüttgen G
J Am Acad Dermatol 1986 Oct;15(4 Pt 2):735-40. doi: 10.1016/s0190-9622(86)70228-4. PMID: 3534016
Nevoid basal cell carcinoma syndrome. Profile of genetic and environmental factors in oncogenesis.
Howell JB
J Am Acad Dermatol 1984 Jul;11(1):98-104. doi: 10.1016/s0190-9622(84)70141-1. PMID: 6736355

Prognosis

Genomic Stability in Syndromic Basal Cell Carcinoma.
Chiang A, Jaju PD, Batra P, Rezaee M, Epstein EH Jr, Tang JY, Sarin KY
J Invest Dermatol 2018 May;138(5):1044-1051. Epub 2017 Oct 27 doi: 10.1016/j.jid.2017.09.048. PMID: 29111235
Cutaneous malignancies in HIV.
Chang AY, Doiron P, Maurer T
Curr Opin HIV AIDS 2017 Jan;12(1):57-62. doi: 10.1097/COH.0000000000000338. PMID: 27875372
NAV3 copy number changes and target genes in basal and squamous cell cancers.
Maliniemi P, Carlsson E, Kaukola A, Ovaska K, Niiranen K, Saksela O, Jeskanen L, Hautaniemi S, Ranki A
Exp Dermatol 2011 Nov;20(11):926-31. doi: 10.1111/j.1600-0625.2011.01358.x. PMID: 21995814
High incidence of second basal cell skin cancers.
Levi F, Randimbison L, Maspoli M, Te VC, La Vecchia C
Int J Cancer 2006 Sep 15;119(6):1505-7. doi: 10.1002/ijc.22000. PMID: 16642479
Squamous and basal cell cancers directly invading major salivary glands.
Talmi YP, Gal R, Finkelstein Y, Nobel M, Shvilli I, Zohar Y
Ann Plast Surg 1991 May;26(5):483-7. doi: 10.1097/00000637-199105000-00014. PMID: 1952725

Clinical prediction guides

Superficial Basal Cell Cancers Demonstrate Higher Rates of Mixed Histology on High-Risk Anatomical Sites.
Petersen ET, Ahmed SR, Pradhan D, MacFarlane DF
Dermatol Surg 2020 Jun;46(6):747-751. doi: 10.1097/DSS.0000000000002162. PMID: 31652222
Radiation-sensitive genetically susceptible pediatric sub-populations.
Kleinerman RA
Pediatr Radiol 2009 Feb;39 Suppl 1(Suppl 1):S27-31. Epub 2008 Dec 16 doi: 10.1007/s00247-008-1015-6. PMID: 19083227Free PMC Article
Expression of cell proliferation and apoptosis markers in papillomas and cancers of conjunctiva and eyelid.
Reszec J, Sulkowska M, Koda M, Kanczuga-Koda L, Sulkowski S
Ann N Y Acad Sci 2004 Dec;1030:419-26. doi: 10.1196/annals.1329.052. PMID: 15659825
Grenz ray-induced nonmelanoma skin cancer.
Frentz G
J Am Acad Dermatol 1989 Sep;21(3 Pt 1):475-8. doi: 10.1016/s0190-9622(89)70210-3. PMID: 2674211
Nevoid basal-cell carcinoma syndrome.
Gorlin RJ
Medicine (Baltimore) 1987 Mar;66(2):98-113. doi: 10.1097/00005792-198703000-00002. PMID: 3547011

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