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Sleep myoclonus

MedGen UID:
155544
•Concept ID:
C0751352
•
Sign or Symptom
Synonyms: Myoclonus, Nocturnal; Myoclonus, Sleep; Nocturnal Myoclonus; Sleep Myoclonus
 
HPO: HP:0012323

Definition

Myoclonus that occurs during the initial phases of sleep. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Sleep myoclonus

Professional guidelines

PubMed

Differential diagnosis of epileptic seizures in infancy including the neonatal period.
Cross JH
Semin Fetal Neonatal Med 2013 Aug;18(4):192-5. Epub 2013 Apr 30 doi: 10.1016/j.siny.2013.04.003. PMID: 23642846
Treatment of sleep disturbances in depressed patients.
Neylan TC
J Clin Psychiatry 1995;56 Suppl 2:56-61. PMID: 7844108

Recent clinical studies

Etiology

Transient benign paroxysmal movement disorders in infancy.
Mosca S, Martins J, Temudo T
Rev Neurol 2022 Feb 16;74(4):135-140. doi: 10.33588/rn.7404.2021326. PMID: 35148422Free PMC Article
Transient benign paroxysmal movement disorders in infancy.
Fernández-Alvarez E
Eur J Paediatr Neurol 2018 Mar;22(2):230-237. Epub 2018 Jan 12 doi: 10.1016/j.ejpn.2018.01.003. PMID: 29366536
Synkinetic blepharoclonus.
Jacome DE
J Neuroophthalmol 2000 Dec;20(4):276-84. PMID: 11130758
Paroxysmal non-epileptic events in children: a retrospective study over a period of 10 years.
Bye AM, Kok DJ, Ferenschild FT, Vles JS
J Paediatr Child Health 2000 Jun;36(3):244-8. doi: 10.1046/j.1440-1754.2000.00496.x. PMID: 10849225
Myoclonus and epilepsies.
Fejerman N
Indian J Pediatr 1997 Sep-Oct;64(5):583-602. doi: 10.1007/BF02726110. PMID: 10771893

Diagnosis

Transient benign paroxysmal movement disorders in infancy.
Mosca S, Martins J, Temudo T
Rev Neurol 2022 Feb 16;74(4):135-140. doi: 10.33588/rn.7404.2021326. PMID: 35148422Free PMC Article
Paroxysmal non-epileptic events in infancy: five cases with typical features.
Nagy E, Hollody K
Epileptic Disord 2019 Oct 1;21(5):458-462. doi: 10.1684/epd.2019.1098. PMID: 31649006
Benign neonatal sleep myoclonus: frequently misdiagnosed as neonatal seizures.
Goraya JS, Singla G, Mahey H
Indian Pediatr 2015 Aug;52(8):713-4. PMID: 26388639
Clinical imitators of infantile spasms.
Donat JF, Wright FS
J Child Neurol 1992 Oct;7(4):395-9. doi: 10.1177/088307389200700412. PMID: 1469248
Benign neonatal sleep myoclonus.
Coulter DL, Allen RJ
Arch Neurol 1982 Mar;39(3):191-2. doi: 10.1001/archneur.1982.00510150061016. PMID: 7065938

Therapy

Benign neonatal sleep myoclonus: our experience of 15 Japanese cases.
Suzuki Y, Toshikawa H, Kimizu T, Kimura S, Ikeda T, Mogami Y, Yanagihara K
Brain Dev 2015 Jan;37(1):71-5. Epub 2014 Apr 18 doi: 10.1016/j.braindev.2014.03.010. PMID: 24750849
Benign neonatal sleep myoclonus: history and semiology.
Kaddurah AK, Holmes GL
Pediatr Neurol 2009 May;40(5):343-6. doi: 10.1016/j.pediatrneurol.2008.11.011. PMID: 19380069
Employing mirtazapine to aid benzodiazepine withdrawal.
Chandrasekaran PK
Singapore Med J 2008 Jun;49(6):e166-7. PMID: 18581012
Paroxysmal non-epileptic events in children: a retrospective study over a period of 10 years.
Bye AM, Kok DJ, Ferenschild FT, Vles JS
J Paediatr Child Health 2000 Jun;36(3):244-8. doi: 10.1046/j.1440-1754.2000.00496.x. PMID: 10849225
Clonazepam treatment of insomnia due to sleep myoclonus.
Oshtory MA, Vijayan N
Arch Neurol 1980 Feb;37(2):119-20. doi: 10.1001/archneur.1980.00500510077019. PMID: 7356405

Prognosis

Benign neonatal sleep myoclonus: a review of the literature.
Maurer VO, Rizzi M, Bianchetti MG, Ramelli GP
Pediatrics 2010 Apr;125(4):e919-24. Epub 2010 Mar 29 doi: 10.1542/peds.2009-1839. PMID: 20351003
Paroxysmal non-epileptic events in children: a retrospective study over a period of 10 years.
Bye AM, Kok DJ, Ferenschild FT, Vles JS
J Paediatr Child Health 2000 Jun;36(3):244-8. doi: 10.1046/j.1440-1754.2000.00496.x. PMID: 10849225
Myoclonus and epilepsies.
Fejerman N
Indian J Pediatr 1997 Sep-Oct;64(5):583-602. doi: 10.1007/BF02726110. PMID: 10771893
Benign neonatal sleep myoclonus.
Noone PG, King M, Loftus BG
Ir Med J 1995 Sep-Oct;88(5):172. PMID: 8575908
Benign neonatal sleep myoclonus.
Coulter DL, Allen RJ
Arch Neurol 1982 Mar;39(3):191-2. doi: 10.1001/archneur.1982.00510150061016. PMID: 7065938

Clinical prediction guides

Paroxysmal nonepileptic events in children with epilepsy.
Ito Y, Kidokoro H, Negoro T, Tanaka M, Okai Y, Sakaguchi Y, Ogawa C, Takeuchi T, Ohno A, Yamamoto H, Nakata T, Maesawa S, Watanabe K, Takahashi Y, Natsume J
Epilepsy Res 2017 May;132:59-63. Epub 2017 Feb 27 doi: 10.1016/j.eplepsyres.2017.02.009. PMID: 28315806
Benign neonatal sleep myoclonus: our experience of 15 Japanese cases.
Suzuki Y, Toshikawa H, Kimizu T, Kimura S, Ikeda T, Mogami Y, Yanagihara K
Brain Dev 2015 Jan;37(1):71-5. Epub 2014 Apr 18 doi: 10.1016/j.braindev.2014.03.010. PMID: 24750849
Benign convulsions in newborns and infants: occurrence, clinical course and prognosis.
Hrastovec A, Hostnik T, Neubauer D
Eur J Paediatr Neurol 2012 Jan;16(1):64-73. Epub 2011 Nov 23 doi: 10.1016/j.ejpn.2011.10.006. PMID: 22116015
Periodic leg movements during sleep and sleep disturbances in elders.
Youngstedt SD, Kripke DF, Klauber MR, Sepulveda RS, Mason WJ
J Gerontol A Biol Sci Med Sci 1998 Sep;53(5):M391-4. doi: 10.1093/gerona/53a.5.m391. PMID: 9754146
Clonazepam treatment of insomnia due to sleep myoclonus.
Oshtory MA, Vijayan N
Arch Neurol 1980 Feb;37(2):119-20. doi: 10.1001/archneur.1980.00500510077019. PMID: 7356405

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