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Hyperalgesia, Primary

MedGen UID:
148257
•Concept ID:
C0751211
•
Sign or Symptom
Synonyms: Hyperalgia, Primary; Primary Hyperalgia; Primary Hyperalgias

Professional guidelines

PubMed

Evolving approaches in neonatal postoperative pain management.
Visoiu M
Semin Pediatr Surg 2022 Aug;31(4):151203. Epub 2022 Aug 1 doi: 10.1016/j.sempedsurg.2022.151203. PMID: 36038217
The evolution of primary hyperalgesia in orthopedic surgery: quantitative sensory testing and clinical evaluation before and after total knee arthroplasty.
Martinez V, Fletcher D, Bouhassira D, Sessler DI, Chauvin M
Anesth Analg 2007 Sep;105(3):815-21. doi: 10.1213/01.ane.0000278091.29062.63. PMID: 17717244Free PMC Article
Pain management: physiopathology, future research and endpoints.
Sosnowski M
Support Care Cancer 1993 Mar;1(2):79-88. doi: 10.1007/BF00366900. PMID: 8143105

Recent clinical studies

Etiology

Wound Infusion of 0.35% Levobupivacaine Reduces Mechanical Secondary Hyperalgesia and Opioid Consumption After Cesarean Delivery: A Prospective, Randomized, Triple-Blind, Placebo-Controlled Trial.
Gómez-Ríos MÁ, Codesido-Barreiro P, Seco-Vilariño C, Calvín-Lamas M, Curt-Nuño F, Nieto-Serradilla L, Rabuñal-Álvarez MT, Fernández-Rodríguez F, Peteiro-Cartelle J, Pensado-Boo R, Bou G, Pensado-Castiñeiras A, Casans-Francés R
Anesth Analg 2022 Apr 1;134(4):791-801. doi: 10.1213/ANE.0000000000005917. PMID: 35086112
Hyperalgesia induced by cutaneous freeze injury for testing analgesics in healthy volunteers.
Chassaing C, Schmidt J, Eschalier A, Cardot JM, Dubray C
Br J Clin Pharmacol 2006 Apr;61(4):389-97. doi: 10.1111/j.1365-2125.2006.02582.x. PMID: 16542199Free PMC Article

Diagnosis

Wound Infusion of 0.35% Levobupivacaine Reduces Mechanical Secondary Hyperalgesia and Opioid Consumption After Cesarean Delivery: A Prospective, Randomized, Triple-Blind, Placebo-Controlled Trial.
Gómez-Ríos MÁ, Codesido-Barreiro P, Seco-Vilariño C, Calvín-Lamas M, Curt-Nuño F, Nieto-Serradilla L, Rabuñal-Álvarez MT, Fernández-Rodríguez F, Peteiro-Cartelle J, Pensado-Boo R, Bou G, Pensado-Castiñeiras A, Casans-Francés R
Anesth Analg 2022 Apr 1;134(4):791-801. doi: 10.1213/ANE.0000000000005917. PMID: 35086112
Hyperalgesia induced by cutaneous freeze injury for testing analgesics in healthy volunteers.
Chassaing C, Schmidt J, Eschalier A, Cardot JM, Dubray C
Br J Clin Pharmacol 2006 Apr;61(4):389-97. doi: 10.1111/j.1365-2125.2006.02582.x. PMID: 16542199Free PMC Article

Therapy

Wound Infusion of 0.35% Levobupivacaine Reduces Mechanical Secondary Hyperalgesia and Opioid Consumption After Cesarean Delivery: A Prospective, Randomized, Triple-Blind, Placebo-Controlled Trial.
Gómez-Ríos MÁ, Codesido-Barreiro P, Seco-Vilariño C, Calvín-Lamas M, Curt-Nuño F, Nieto-Serradilla L, Rabuñal-Álvarez MT, Fernández-Rodríguez F, Peteiro-Cartelle J, Pensado-Boo R, Bou G, Pensado-Castiñeiras A, Casans-Francés R
Anesth Analg 2022 Apr 1;134(4):791-801. doi: 10.1213/ANE.0000000000005917. PMID: 35086112
Lack of effect of central nervous system-active doses of nabilone on capsaicin-induced pain and hyperalgesia.
Kalliomäki J, Philipp A, Baxendale J, Annas P, Karlsten R, Segerdahl M
Clin Exp Pharmacol Physiol 2012 Apr;39(4):336-42. doi: 10.1111/j.1440-1681.2012.05674.x. PMID: 22233155
Hyperalgesia induced by cutaneous freeze injury for testing analgesics in healthy volunteers.
Chassaing C, Schmidt J, Eschalier A, Cardot JM, Dubray C
Br J Clin Pharmacol 2006 Apr;61(4):389-97. doi: 10.1111/j.1365-2125.2006.02582.x. PMID: 16542199Free PMC Article

Clinical prediction guides

Lack of effect of central nervous system-active doses of nabilone on capsaicin-induced pain and hyperalgesia.
Kalliomäki J, Philipp A, Baxendale J, Annas P, Karlsten R, Segerdahl M
Clin Exp Pharmacol Physiol 2012 Apr;39(4):336-42. doi: 10.1111/j.1440-1681.2012.05674.x. PMID: 22233155

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